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Incidence and in-hospital mortality of acute aortic dissection in {1.： analysis of {1. Health Insurance Research （CHIRA） Data 201.

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Journal of Geriatric Cardiology 2015年第5期12卷 502-506页

作者： Lei XIA Jing-Hu li Kun {1. Hai-Yun WU The Administrating Office Chinese PLA General Hospital Beijing China institute of Geriatric Cardiology Chinese PLA General Hospital Beijing China china Health Insurance Research Association Beijing China Brainpower Phama Consulting Co. Ltd. Beijing China

Objective Acute aortic dissection （AAD） is a catastrophic event with high early mortality rate, but to date, no data on the incidence of AAD in {1.'s Mainland is available. This study aimed to estimate the inciden... 详细信息

Objective Acute aortic dissection （AAD） is a catastrophic event with high early mortality rate, but to date, no data on the incidence of AAD in china's Mainland is available. This study aimed to estimate the incidence of AAD in china and characterize the clinical profile, management and in-hospital outcomes of this vascular event. Methods We used the china Health Insurance Research Data （the CHIRA Data） 2011 which comprises all inpatient hospital records （300,886） during the period of Jan. 1st 2011 to Dec. 31.2011 of 3,335,000 randomly sampled beneficiaries （1,718,500 men and 1,616,500 women） from 25 cities and counties in different economic-geographic regions of china's Mainland. Patients with acute aortic dissection were identified according to International Classification of Disease 10m Revision （ICD-10） of I71.0, The estimated incidence of AAD was calculated using the equation： estimated incidence = 2.0 × （40% × hospital admission rate）＋ 60% × hospital admission rate. Results The hospital admission rate was 2.0/100,000 （65/3,325,000, 95% CI： 1.2-2.8）. The estimated annual incidence of AAD was 2.8/100,000 （95% CI： 1.9-3.6） and was higher in male than in female （3.7 vs. 1.5, P 〈 0.001）. The mean age was 58.9 ± 13.4 years. During the mean hospital stay of 23 ±6 days, the overall in-hospital mortality was 13.9% （9/65）. Conclusions Our study showed relatively lower but not negligible incidence and in-hospital mortality of AAD in the mainland of china. The mean age of patients with AAD in chinese was younger than that reported by researches from west countries, while the male to female incidence ratio is similar to those reported by other studies.

关键词： Acute aortic dissection china health insurance research Incidence rate

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High-Quality InSb Grown on Semi-Insulting GaAs Substrates by Metalorganic Chemical Vapor Deposition for Hall Sensor Application

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chinese Physics Letters 2019年第1期36卷 52-55页

作者： Xin li Yu {1. Min Xiong Qi-Hua Wu Yan Teng Xiu-Jun Hao Yong Huang Shuang-Yuan Hu Xin Zhu School of Nano Technology and Nano Bionics University of Science and Technology of China Key Laboratory of Nanodevices and Applications Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of Sciences School of Physical Science and Technology Shanghai Tech University Suzhou Matrix Opto Co. Ltd

High-quality InSb epilayers are grown on semi-insulting GaAs substrates by metalorganic chemical vapor deposition using an indium pre-deposition technique. The influence of Ⅴ/Ⅲ ratio and indium pre-deposition time on the surface morphology, crystalline quality and electrical properties of the InSb epilayer is systematically investigated using Nomarski microscopy, atomic force microscopy, high-resolution x-ray diffraction, Hall measurement and contactless sheet resistance measurement. It is found that a 2-μm-thick InSb epilayer grown at 450℃ with a Ⅴ/Ⅲ ratio of 5 and an indium pre-deposition time of 2.5s exhibits the optimum material quality, with a root-meansquare surface roughness of only 1.2 nm, an XRD rocking curve with full width at half maximum of 358 arcsec and a room-temperature electron mobility of 4.6 × 1.~4 cm^2/V·s. These values are comparable with those grown by molecular beam epitaxy. Hall sensors are fabricated utilizing a 600-nm-thick InSb epilayer. The output Hall voltages of these sensors exceed 1. mV with the input voltage of 1.V at 9.3 mT and the electron mobility of 3.2 × 1.~4 cm^2/V·s is determined, which indicates a strong potential for Hall applications.

关键词： Hall Sensor Application Metal organic chemical vapor deposition Gallium arsenide

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Enrichment factors of movable hydrocarbons in lacustrine shale oil and exploration potential of shale oil in Gulong Sag,Songliao Basin,NE {1.

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Petroleum Exploration and Development 2023年第3期50卷 520-533页

作者： zhao Wenzhi BIAN Congsheng {1. Yongxin ZHANG Jinyou HE Kun {1.U Wei ZHANG Bin LEI Zhengdong {1.U Chang ZHANG Jingya GUAN Ming {1.U Shijul ZWZ Academician Research Studio PetroChina Research Institute of Petroleum Exploration&DevelopmentBeijing 100083China Petrochina Research {1. of Petroleum Exploration&Development Beijing 100083China Exploration and Development Research institute of Petro{1. Daqing Oilfield Company Daqing 163712China

The geological characteristics and production practices of the major middle-and high-maturity shale oil exploration areas in china are *** with laboratory results,it is clear that three essential conditions,*** initial production,commercial cumulative oil production of single well,and large-scale recoverable reserves confirmed by the testing production,determine whether the continental shale oil can be put into large-scale commercial *** quantity and qua{1.ty of movable hydrocarbons are confirmed to be crucial to economic development of shale oil,and focuses in evaluation of shale oil enrichment area/*** evaluation indexes of movable hydrocarbon enrichment include:(1.the material basis for forming retained hydrocarbon,including TOC>2%(preferentially 3%-4%),and typeⅠ-Ⅱkerogens;(2)the mobi{1.ty of retained hydrocarbon,which is closely related to the hydrocarbon composition and flow behaviors of {1.ght/heavy components,and can be evaluated from the perspectives of thermal maturity(Ro),gas-oil ratio(GOR),crude oil density,qua{1.ty of hydrocarbon components,preservation conditions;and(3)the reservoir characteristics associated with the engineering reconstruction,including the main pore throat distribution zone,reservoir physical properties(including fractures),lamellation feature and diagenetic stage,***,1. evaluation indexes in three categories and their reference values are *** evaluation indicates that the {1.ght shale oil zones in the Gulong Sag of Song{1.ao Basin have the most favorable enrichment conditions of movable hydrocarbons,followed by {1.ght oil and black oil zones,containing 20.8×1.^(8) t {1.ght oil resources in reservoirs with R_(0)>1.2%,pressure coefficient greater than 1.4,effective porosity greater than 6%,crude oil density less than 0.82 g/cm^(3),and GOR>1.0 m/m^(3).The shale oil in the Gulong Sag can be explored and developed separately by the categories(resource sweet spot,engineering sweet

关键词： Gulong Sag continental shale oil movable hydrocarbon enrichment factor enrichment zone/interval evaluation material basis component flow engineering-associated factor

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基于光学微血流成像技术的相干光断层扫描血流成像对视网膜血流定量分析的可重复性评价

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眼科 2018年第2期27卷 107-110页

作者：赵琦王霄娜杨文利魏文斌 WANG Ruikang K. 游启生楚仲頔辛晨首都医科大学附属北京同仁医院北京同仁眼科中心眼科学与视觉科学北京市重点实验室北京市眼科研究所 100730 华盛顿大学生物工程系 98195

目的评价基于光学微血流成像技术(OMAG)的相干光断层扫描血流成像(OCTA)在正常眼视网膜血流定量分析的可重复性。设计诊断试验。研究对象 40名(40眼)健康志愿者,年龄22~55岁,平均(33.0±8.8)岁。方法使用Zeiss Cirrus HD-OCT 5000扫描,... 详细信息

目的评价基于光学微血流成像技术(OMAG)的相干光断层扫描血流成像(OCTA)在正常眼视网膜血流定量分析的可重复性。设计诊断试验。研究对象 40名(40眼)健康志愿者,年龄22~55岁,平均(33.0±8.8)岁。方法使用Zeiss Cirrus HD-OCT 5000扫描,以基于OMAG技术的AngioPlex^(TM)软件对视网膜浅层3 mm×3 mm OCTA图像的血流长度密度(VLD)、灌注密度(PD)及黄斑中心凹无血流信号区(FAZ)面积、周长、圆形度进行自动定量分析。采用变异系数(CV)评价观察日内及观察日间重复性,组内相关系数(ICC)评价观察者间再现性。主要指标变异系数(CV)和组内相关系数(ICC)。结果各血流参数观察日内CV(1.2±1.0)%^(4.2±5.5)%,均≤4.2%,观察日间CV(1.4±0.8)%^(4.6±4.9)%,均≤4.6%,观察日间CV高于观察日内CV,而中心凹、FAZ各参数CV高于旁中心凹CV;各血流参数观察者间ICC(0.923~0.994),均≥0.923,中心凹、FAZ各参数ICC高于旁中心凹。结论基于OMAG技术的OCTA对正常眼视网膜浅层血流各参数测量均具有较好的重复性和再现性。

关键词：相干光断层扫描血流成像光学微血流成像重复性再现性视网膜浅层血流血流定量

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江蓠中类菌孢素氨基酸(MAAs)分离纯化及其成分分析

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水产学报 2011年第12期35卷 1829-1836页

作者：金宁宁张朝辉李八方严芳芳孙京沙中国海洋大学食品科学与工程学院

存在于海洋生物中,尤其是藻类中的类菌孢素氨基酸(mycosporine-like amino acids,MAAs),是一种吸收紫外线的物质,可用于紫外线防护品的原料,具有商业开发的前景。对湛江沿海产江蓠中MAAs进行了分离和结构鉴定,确定江蓠MAAs的主要组成及... 详细信息

存在于海洋生物中,尤其是藻类中的类菌孢素氨基酸(mycosporine-like amino acids,MAAs),是一种吸收紫外线的物质,可用于紫外线防护品的原料,具有商业开发的前景。对湛江沿海产江蓠中MAAs进行了分离和结构鉴定,确定江蓠MAAs的主要组成及比例。利用C-1. Sep-Pak固相萃取柱和半制备型HPLC对湛江产江蓠中MAAs成分进行分离纯化。根据化合物的特征、紫外吸收波长和波谱数据鉴定其主要成分的结构,并结合参考文献确定湛江产江蓠MAAs的4种主要成分是palythine、shinorine、palythinol和porphyra-334,其比例约为4.9∶1.{1.∶9.9。同时,比较了UV法和HPLC法对湛江产江蓠MAAs主要成分porphyra-334含量检测的准确度,建立了两种检测方法的拟合曲线,并通过试验验证,最终确立了HPLC对MAAs主要组成成分的检测方法。

关键词：江蓠类菌孢素氨基酸 ESI-TOF/MS 检测方法

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氨基酸功能化二硫化钼/环氧树脂复合材料耐水性能的研究

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中国胶粘剂 2024年第8期33卷 29-34页

作者：曹宇鑫吴绵园赵明张斌孙明明张绪刚张雪李坚辉黑龙江省科学院石油化学研究院黑龙江哈尔滨150040 哈尔滨工程大学黑龙江哈尔滨150001 哈尔滨理工大学黑龙江哈尔滨150040

环氧树脂因其优异物理化学性能在各种高新领域得到了重要发展。近年来随着材料科学在某些极端环境下的需求越来越多,对提高环氧树脂的耐水性需求日渐迫切。本文首先制备了氨基乙酸(Gly)改性二硫化钼(MoS_(2))纳米片,然后用其改性环氧树... 详细信息

环氧树脂因其优异物理化学性能在各种高新领域得到了重要发展。近年来随着材料科学在某些极端环境下的需求越来越多,对提高环氧树脂的耐水性需求日渐迫切。本文首先制备了氨基乙酸(Gly)改性二硫化钼(MoS_(2))纳米片,然后用其改性环氧树脂,制备了Gly-MoS_(2)/环氧树脂复合材料。对其结构、微观形貌、力学性能、热机械性能和吸水率等指标进行表征。研究结果表明:(1.成功制备了目标产物,经氨基乙酸剥离和改性的MoS_(2)纳米片在树脂基体中分散更均匀,在保证适宜的横向尺寸的同时厚度更薄,与基体树脂相容性更好。(2)随着纳米片添加量的增加,树脂体系水煮后的常温和高温剪切强度、拉伸强度和抗冲击强度均有提升。这是由于改性后纳米片在基体中分散均匀,且与环氧基形成更稳定的海岛结构,从而提升了材料本身的耐水性。(3)热机械性能测试表明,Gly-MoS_(2)纳米片对增强材料水煮后的耐温性有着重要的作用。吸水率测试表明,Gly-MoS_(2)极大地改善了环氧树脂的耐水性能,并且随着Gly-MoS_(2)纳米片的增加,吸水率随之降低。其中1.00%Gly-MoS_(2)/环氧树脂体系的耐水效果最好,水煮1.2 h后最终吸水率仅为1.2%。

关键词：纳米复合材料聚合物基复合材料耐水性机械性能

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Azvudine is a thymus-homing anti-SARS-CoV-2 drug effective in treating COVID-1. patients

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Signal Transduction and Targeted Therapy 2022年第1期7卷 228-242页

作者： Jin-Lan Zhang Yu-Huan li Lu-Lu Wang Hong-Qi liu Shuai-Yao Lu Yong liu Ke li Bin liu Su-Yun li Feng-Min Shao Kun Wang Ning Sheng Rui li Jin-Jin Cui Pei-Chun Sun Chun-Xia Ma Bo Zhu Zhe Wang Yuan-Hao Wan Shi-Shan Yu Yongsheng Che Chao-Yang Wang Chen Wang Qiangqian Zhang li-Min zhao Xiao-Zhong Peng Zhenshun Cheng Jun-Biao Chang Jian-Dong Jiang State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100050China institute of Medicinal Biotechnology Chinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100050China institute of Medical Biology Chinese Academy of Medical Science and Peking Union Medical CollegeKunming 650031 YunnanChina Genuine Biotech.Inc. Pingdingshan 467000 HenanChina Department of Respiratory Medicine Zhongnan Hospital of Wuhan UniversityWuhan Research Center for Infectious Diseases and CancerWuhan 430071 HubeiChina The First Affiliated Hospital of Henan University of {1. Medicine Zhengzhou 450000 HenanChina Department of Internal Medicine Henan Provincial Peoples HospitalZhengzhou 450003 HenanChina Henan Key Laboratory of Organic Functional Molecule and Drug Innovation School of Chemistry and Chemical EngineeringHenan Normal UniversityXinxiang 453007 HenanChina National Clinical Research Center for Respiratory Diseases Chinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100005China School of Chemistry Zhengzhou UniversityZhengzhou 450001 HenanChina

Azvudine(FNC)is a nucleoside analog that inhibits HIV-1.RNA-dependent RNA polymerase(RdRp).Recently,we discovered FNC an agent against SARS-CoV-2,and have taken it into Phase III trial for COVID-1. *** monophosphate analog inhibited SARS-CoV-2 and HCoV-OC43 coronavirus with an EC_(50) between 1.2 and 4.3 μM,depending on viruses or cells,and selective index(SI)in 1.-83 *** administration of FNC in rats revealed a substantial thymus-homing feature,with FNC triphosphate(the active form)concentrated in the thymus and peripheral blood mononuclear cells(PBMC).Treating SARS-CoV-2 infected rhesus macaques with FNC(0.07 mg/kg, qd,orally)reduced viral load,recuperated the thymus,improved lymphocyte profiles,alleviated in flammation and orga n damage,and lessened grou nd・glass opacities in chest *** gle-cell seque ncing suggested the promotion of thymus function by FNC.A randomized,single-arm c{1.nical trial of FNC on compassionate use(n=31.showed that oral FNC(5 mg,qd)cured all COVID-1. patients,with 1.0%viral ribonucleic acid negative conversion in 3.29±2.22 days(range:1.9 days)and 1.0%hospital discharge rate in 9.00±4.93 days(range:2-25 days).The side-effect of FNC is minor and transient dizziness and nausea in 1..1.%(5/31.***,FNC might cure COVID-1. through its anti-SARS-CoV-2 activity concentrated in the thymus,followed by promoted immunity.

关键词： patients inhibited concentrated

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Surface modification with oxygen vacancy in li-rich layered oxide li1.2Mn0.54Ni0.1.Co0.1.O2 for lithium-ion batteries

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Journal of Materials Science & Technology 2019年第6期35卷 994-1002页

作者： Bozhou Chen Bangchuan zhao Jiafeng Zhou Zhitang Fang Yanan Huang Xuebin Zhu Yuping Sun Key Laboratory of Materials Physics Institute of Solid State Physics Chinese Academy of Sciences Hefei 230031 China University of Science and Technology of china Hefei 230026 China High Magnetic Field Laboratory Chinese Academy of Sciences Hefei 230031 China

A couple of layered li-rich cathode materials li1.2Mn0.54Ni0.1.Co0.1.O2 without any carbon modification are successfully synthesized by solvothermal and hydrothermal methods followed by a calcination process. The sample synthesized by the solvothermal method(S-NCM) possesses more homogenous microstructure, lower cation mixing degree and more oxygen vacancies on the surface, compared to the sample prepared by the hydrothermal method(H-NCM). The S-NCM sample exhibits much better cycling performance, higher discharge capacity and more excellent rate performance than H-NCM. At 0.2 C rate,the S-NCM sample delivers a much higher initial discharge capacity of 292.3 mAh g^-1.and the capacity maintains 235 m Ah g^-1.after 1.0 cycles(80.4% retention), whereas the corresponding capacity values are only 269.2 and 1.8.5 m Ah g^-1.40.3% retention) for the H-NCM sample. The S-NCM sample also shows the higher rate performance with discharge capacity of 1.8.3 mAh g^-1.even at a high rate of 1. C, superior to that(46.5 m Ah g^-1. of the H-NCM sample. The superior electrochemical performance of the S-NCM sample can be ascribed to its well-ordered structure, much larger specific surface area and much more oxygen vacancies located on the surface.

关键词： li-rich cathode oxide material Oxygen vacancy Solvothermal method Electrochemical performance

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Extraction of the Structure Functions in τ→3πv Decay Using li Model

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chinese Physics Letters 1998年第12期15卷 868-870页

作者： XIONG zhao-hua CHEN Guo-ming CHEN He-sheng institute of High Energy Physics Chinese Academy of SciencesBeijing 100039

The structure functions in theτ→3πv decay are extracted using the model proposed by *** predictions of li model are compared with KS ones and the data from OPAL *** is found that predictions by the model forωA(Q2)are consistent with the data except for in the high energy region(Q2>{1. GeV2),andωC,ωD,ωE normalized toωA are in reasonable agreement with the experimental *** factors to the Breit-Wigner distribution of a1.and the Lagrangian of this decay are proposed to the model.

关键词： experiment. decay model.

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TS-50304对氯乙烯转化器热水循环系统腐蚀的控制

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聚氯乙烯 2001年第5期29卷 58-60页

作者：王芳李冰许锦华王润宇宁建英佟守义李兆曼天津化工研究设计院天津300131 唐山三友集团冀东化工有限公司河北唐山063021

通过静态腐蚀阻垢实验、动态旋转挂片腐蚀试验、电化学性能测试试验和现场应用等数据证明 ,使用缓蚀阻垢剂TS - 5 0 30 4能够有效控制氯乙烯转化器列管的腐蚀 ,腐蚀泄漏率由使用前的 3 .5次 /月下降到目前的 1.2次

关键词：氯乙烯转化器电石法聚氯乙烯缓蚀阻垢剂转化器列管热水循环系统腐蚀控制

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