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H340LAD+Z电阻点焊接头疲劳性能研究

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汽车工艺与材料 2024年第6期 44-50页

作者：赵奕炳王光耀方刚罗三峰程西西李晓瑜中国汽车工程研究院股份有限公司重庆401122

开展了H340LAD+Z(1.2 mm)-H340LAD+Z(1.2 mm)点焊十字接头和点焊剥离接头疲劳性能及失效模式的研究工作。研究发现,点焊十字接头拉伸试验的最大力为9.0 kN,点焊剥离接头拉伸试验的最大力为1.9 kN,点焊接头硬度最大值为348 HV 1.位于熔... 详细信息

开展了H340LAD+Z(1.2 mm)-H340LAD+Z(1.2 mm)点焊十字接头和点焊剥离接头疲劳性能及失效模式的研究工作。研究发现,点焊十字接头拉伸试验的最大力为9.0 kN,点焊剥离接头拉伸试验的最大力为1.9 kN,点焊接头硬度最大值为348 HV 1.位于熔核区内,点焊十字接头和点焊剥离接头的最大力-疲劳寿命曲线在双对数坐标轴下呈线性关系,且点焊十字接头的疲劳性能优于点焊剥离接头的疲劳性能。最后观察了点焊十字接头和点焊剥离接头的疲劳失效模式及疲劳断口形貌特征,2种接头的失效模式略有差别,疲劳断口形貌均由裂纹源和扩展区组成。

关键词：电阻点焊剥离接头十字接头高强钢疲劳性能

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青蒿琥酯和蒿甲醚的Ⅰ期临床药代动力学研究

中国临床药理学杂志 1988年第2期4卷 76-81页

作者：赵凯存陈芝喜林炳流郭兴伯李国桥宋振玉中国医学科学院药物研究所广州中医学院

本文报道用放射免疫测定法研究青蒿琥酯和蒿甲醚Ⅰ期临床药代动力学结果。静脉注射青蒿琥酯2.0和3.8mg/kg后,血药时程为二房室模型,t_(1.2)β分别为0.5h和O.6—0.8h,稳态分布容积分别为0.1.0.6和0.3—0.4L/kg,整体清除率分别为0.4—1.2... 详细信息

本文报道用放射免疫测定法研究青蒿琥酯和蒿甲醚Ⅰ期临床药代动力学结果。静脉注射青蒿琥酯2.0和3.8mg/kg后,血药时程为二房室模型,t_(1.2)β分别为0.5h和O.6—0.8h,稳态分布容积分别为0.1.0.6和0.3—0.4L/kg,整体清除率分别为0.4—1.2和0.2—0.5L/kg·h。给药后7h累积从尿中排出的药物只有剂量的0.1.6.8％。肌内注射蒿甲醚油剂3.2、6.0和1..0mg/kg后,血药浓度达峰时间约为4—9h,MRT值分别为1..2±0.8、1..6±3.8和1..0±5.8h。结果表明蒿甲醚油剂经肌内注射后在体内存留时间较长。

关键词：青蒿琥酯蒿甲醚临床药代动力学

CHES: A Space-borne Astrometric Mission for the Detection of Habitable Planets of the Nearby Solar-type Stars

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Research in Astronomy and Astrophysics 2022年第7期22卷 32-59页

作者： Jiang-Hui Ji Hai-Tao li Jun-Bo Zhang liang Fang Dong li Su Wang Yang Cao Lei Deng Bao-Quan li Hao Xian Xiao-Dong Gao Ang Zhang Fei li Jia-Cheng liu zhao-Xiang Qi Sheng Jin Ya-Ning liu Guo Chen Ming-Tao li Yao Dong Zi Zhu CAS Key Laboratory of Planetary sciences Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China Key Laboratory of Electronics and Information Technology for Space Systems National Space Science CenterChinese Academy of SciencesBeijing 100190China University of chinese academy of sciences Beijing 100049China institute of Optics and Electronics Chinese Academy of SciencesChengdu 610209China Key Laboratory on Adaptive Optics Chinese Academy of SciencesChengdu 610209China Key Laboratory of Science and Technology on Space Optoelectronic Precision Measurement Chinese Academy of SciencesChengdu 610209China Innovation academy for Microsatel{1.tes of chinese academy of sciences Shanghai 201306China School of Astronomy and Space Science Nanjing UniversityNanjing 210046China Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China

The Closeby Habitable Exoplanet Survey(CHES) mission is proposed to discover habitable-zone Earth-like planets of nearby solar-type stars(~1. pc away from our solar system) via microarcsecond relative *** major scientific objectives of CHES are:to search for Earth Twins or terrestrial planets in habitable zones orbiting1.0 FGK nearby stars;further to conduct a comprehensive survey and extensively characterize nearby planetary *** primary payload is a high-quality,low-distortion,high-stability *** optical subsystem is a coaxial three-mirror anastigmat(TMA) with a 1.2 m-aperture,0°.44 × 0°.44 field of view and 500 nm-900 nm working wave *** camera focal plane is composed of a mosaic of 81.scientific CMOS detectors each with4 k × 4 k *** heterodyne laser interferometric calibration technology is employed to ensure microarcsecond level(1.μas) relative astrometry precision to meet the requirements for detection of Earth-like *** CHES satellite operates at the Sun-Earth L2 point and observes all the target stars for 5 *** will offer the first direct measurements of true masses and inclinations of Earth Twins and super-Earths orbiting our neighbor stars based on microarcsecond astrometry from *** will definitely enhance our understanding of the formation of diverse nearby planetary systems and the emergence of other worlds for solar-type stars,and finally provide insights to the evolution of our own solar system.

关键词： Astrometry and Celestial Mechanics planets and satellites:detection planets and satellites:terrestrial planets stars:solar-type

Electromagnetic wave absorption properties of Ba(CoTi)_(x)Fe_(1.-2x)O_(1.)@BiFeO_(3)in hundreds of megahertz band

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chinese Physics B 2022年第8期31卷 612-620页

作者： Zhi-Biao Xu zhao-Hui Qi Guo-Wu Wang Chang {1.u Jing-Hao Cui Wen-{1.ang {1. Tao Wang Key Laboratory of Magnetism and Magnetic Materials of the Ministry of Education Lanzhou UniversityLanzhou 730000China The institute of Effectiveness Evaluation of Flying Vehicle Beijing 100089China

The high-performance electromagnetic(EM)wave absorption material Ba(Co Ti)_(x)Fe_(1.-2x)O1.@Bi Fe O_(3)was prepared by solid-state reaction,and its EM wave absorption properties were deeply *** results revealed that Ba(Co Ti)x Fe1.-2x O1.@Bi Fe O_(3)could obtain excellent absorption properties in hundreds of megahertz by adjusting the Co^(2+)-Ti^(4+)*** best comprehensive property was obtained for x={1.,where the optimal reflection loss(RL)value reaches-30.42 d B at about 600 MHz with thickness of 3.5 mm,and the corresponding effective absorption band covers the frequency range of 437 MHz-1.***,the EM wave absorption mechanism was studied based on the simulation *** simulated results showed that the excellent EM wave absorption properties of Ba(Co Ti)_(x)Fe_(1.-2x)O1.@Bi Fe O_(3)mainly originated from the internal loss caused by natural resonance,and the interface cancelation further improved the absorption properties and resulted in RL peaks.

关键词： microwave absorption M-type ferrite high permeability impedance matching

Tumor regression grades:Potential outcome predictor of locally advanced rectal adenocarcinoma after preoperative radiotherapy

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World Journal of Gastroenterology 2015年第6期21卷 1851-1856页

作者： Yi-Fan Peng Wei-Dong Yu Hong-Da Pan lin Wang Ming li Yun-Feng Yao Jun zhao Jin Gu Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Department of Colorectal Surgery Peking University Cancer Hospital and Institute institute of C{1.nical Molecular Biology People’s Hospital Peking University

AIM:To analyze tumor regression grade(TRG)for prognosis of locally advanced rectal adenocarcinoma(LARA)treated with preoperative ***:One hundred and ninety patients with clinical stageⅡ/ⅢLARA were *** patients underwent radical surgery(between 2004 and 201.)after 30-Gy/1.-fraction preoperative radiotherapy(preRT).All 1.0 patients received a short course of preRT and were reassessed for disease recurrence and survival;the slides of surgical specimens were reviewed and classified according to Mandard *** compared patients with good response(Mandard TRG1.or TRG2)vs patients with bad/poor response(Mandard TRG3-5).Outcomes evaluated were 5-year overall survival(OS),5-year disease-free survival(DFS),and local,distant and mixed ***’s exact test orχ2 test,logrank test and proportional hazards regression analysis were used to calculate the probability that Mandard TRG was associated with patient ***:One hundred and sixty-six of 1.0 patients(87.4%)were identified as Mandard bad responders(TRG3-5).High Mandard grade was correlated with tumor height(41.7%1.P=0.031..In univariate survival analysis,Mandard grade bad responders had significantly worse OS and DFSthan good responders(TRG1.2)(OS,83.1.vs 96.4%,P=0.000;DFS,72.3%vs 92.0%,P=0.002).In multivariate survival analysis,Mandard bad responders had significantly worse DFS than Mandard good responders(DFS 3.8 years(95%CI:1.2-1..2 years,P=0.026).CONCLUSION:Mandard grade good responders had a favorable *** may be a potential predictor for DFS in LARA after pre-RT.

关键词： Tumor regression grade Preoperative radiotherapy R

磷石膏转化法制硫酸钾第一阶段反应条件的研究

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沈阳化工学院学报 2001年第2期15卷 85-88页

作者：赵长伟赵妍郭瓦力沈阳化工学院辽宁沈阳110021

通过正交试验对磷石膏转化法生产硫酸钾第一阶段反应过程中的影响因素进行研究 ,通过极差分析 ,确定过程的适宜工艺条件 :反应温度 5 0℃ ,反应时间 2 0min ,固液比 0 .7,配料比(SO4 2 - ∶2NH4 + ) =1.1 .

关键词：磷石膏转化法正交法硫酸钾反应条件

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剑麻斑马纹病抗病新品种——热麻1.剑麻

热带作物学报 2024年第7期45卷 1371-1377页

作者：张燕梅李俊峰陆军迎赵艳龙鹿志伟杨子平柯智周文钊中国热带农业科学院南亚热带作物研究所/海南省热带作物营养重点实验室/湛江市热带作物遗传改良重点实验室广东湛江524091

斑马纹病是剑麻的主要病害之一,严重影响了剑麻产业的发展,目前关于斑马纹病的致病机制尚不清楚。为了培育出剑麻斑马纹病抗病新品种,本研究分别以剑麻斑马纹病抗病品种粤西1.4和感病品种H.1.648为父母本进行回交,获得回交后代热麻1.... 详细信息

斑马纹病是剑麻的主要病害之一,严重影响了剑麻产业的发展,目前关于斑马纹病的致病机制尚不清楚。为了培育出剑麻斑马纹病抗病新品种,本研究分别以剑麻斑马纹病抗病品种粤西1.4和感病品种H.1.648为父母本进行回交,获得回交后代热麻1.剑麻。利用常规方法对热麻1.剑麻叶形、叶色、叶缘刺有无、叶缘刺类型、叶顶刺类型、叶长、叶宽、叶基厚度、顶刺长、顶刺基部宽、株高、花序形状、花轴高、花梗数、花、果实、种子、年展叶数、周期展叶数、生命周期、纤维率等进行分析,采用壁低渗火焰干燥法、流式细胞术结合菌斑接种法对热麻1.剑麻倍性、基因组大小以及对烟草疫霉的抗性等进行鉴定。结果表明:热麻1.剑麻叶片剑形、肉质、刚硬、叶片灰绿,叶面平整有蜡粉,叶顶有1.2~2.0 cm锐刺,叶缘无刺,叶片绕茎呈螺旋状排列上升;叶长约1.0 cm,叶宽约1. cm,叶基厚度约3.5 cm。株高1.8~2.5 m,圆锥形花序,花轴高3~7 m,花梗数20~32个,完全花、花黄色、花瓣6枚;蒴果、长圆形、成熟时黑褐色,种子半月形,黑色、纸质;周期展叶360~400片;纤维率约3.5%,纤维长约1.0 cm;生命周期6~9 a;热麻1.剑麻为四倍体(2X=4n),染色体数目为1.4~1.8,2C DNA含量为1..69 pg,对烟草疫霉高度抗病或免疫,有望成为剑麻斑马纹病发病区的先锋品种。

关键词：热麻1.剑麻斑马纹病抗性

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基于多动物模型药效评价体系研究羚羊感冒口服液儿童用药剂量

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中国药物警戒 2024年第2期21卷 121-126页

作者：孙绮悦赵荣华包蕾郭姗姗耿子涵李舒冉徐英莉张敬升崔晓兰孙静中国中医科学院中药研究所北京100029

目的确定羚羊感冒口服液儿童用药的有效性和最佳剂量范围,增加其儿童用法用量,为儿童临床应用提供参考。方法基于多动物模型药效评价体系,采用反映主要功能主治的5种相应幼龄动物模型,包括甲型H1.1流感病毒感染致小鼠肺炎模型;冰醋酸致... 详细信息

目的确定羚羊感冒口服液儿童用药的有效性和最佳剂量范围,增加其儿童用法用量,为儿童临床应用提供参考。方法基于多动物模型药效评价体系,采用反映主要功能主治的5种相应幼龄动物模型,包括甲型H1.1流感病毒感染致小鼠肺炎模型;冰醋酸致小鼠腹腔毛细血管通透性增加急性炎症模型;氨水雾化致小鼠咳嗽模型;冰醋酸致小鼠疼痛模型;脂多糖(LPS)致家兔发热模型,分别观察羚羊感冒口服液的人用剂量(儿童)0.1.0.2、0.4、0.6、0.8、1.0mL·kg^(-1.·d^(-1.6个剂量组抗病毒、抗炎、止咳、镇痛及解热的有效性,按体表面积换算公式换算为动物用量:小鼠用量分别为{1.、4、6、8、1. mL·kg^(-1.·d^(-1.;家兔用量分别为0.3、0.6、{1.、1.8、2.4、3.0 mL·kg^(-1.·d^(-1.。最终根据结果确定儿童最佳剂量范围。结果羚羊感冒口服液在所试剂量范围内均可在一定程度上降低小鼠肺指数、抑制小鼠毛细血管通透性、减少小鼠咳嗽次数及扭体次数、降低家兔体温,其中发挥稳定药效的剂量范围分别为4.0~8.0 mL·kg^(-1.·d^(-1.和{1.~2.4m L·kg^(-1.·d^(-1.,相当于人用剂量0.4~0.8 m L·kg^(-1.·d^(-1.。结论羚羊感冒口服液在0.4~0.8 mL·kg^(-1.·d^(-1.剂量范围内产生稳定有效的抗病毒、抗炎、止咳、镇痛及解热作用,换算成不同年龄小儿临床推荐用量为1.3岁:每次5 mL、每日{1.次;4~6岁:每次5 mL、每日1.3次;7~1.岁:每次5 mL、每日2~4次。

关键词：羚羊感冒口服液儿童抗病毒抗炎镇痛止咳解热多动物模型小鼠家兔

Manipulation of successive crystalline transformations to control electron transfer and switchable functions

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National Science Review 2018年第4期5卷 507-515页

作者： Cheng-Qi Jiao Wen-Jing Jiang Yin-Shan Meng Wen Wen liang {1. Jun-li Wang Ji-Xiang Hu Gagik G.Gurzadyan Chun-Ying Duan Tao liu State Key Laboratory of Fine Chemicals Dalian University of Technology institute of Artificial Photosynthesis State Key Laboratory of Fine Chemicals Dalian University of Technology

Electron transfer in solid is crucial to switchable magnetic,electrical,optical and mechanical ***,it is a formidable challenge to control electron-transfer behaviors via manipulation of crystalline phases,especially through dynamic crystalline ***,three crystalline phases of an{Fe2Co2}compound were obtained via enhancement of intermolecularπ···πinteractions inducingsuccessive single-crystal-to-single-crystal transformations,from solvated 1.2CH3OH·4H2O,to desolvated1.and its polymorph 1. accompanying electron transfer.1.2CH3OH·4H2O showed thermally inducedreversible intermetallic electron transfer in mother *** electron-transfer behavior was observed in 1.1a showed reversible intermetallic electron transfer upon thermal treatment or alternative irradiation with808-and 532-nm lasers at cryogenic *** electron-transfer behaviors significantly change the magnetic and optical properties,providing a strategy to realize different electron-transfer behaviors andswitchable functions viaπ···πinteractions manipulated dynamic crystalline transformation.

关键词： electron-transfer dynamic structural transformation successive crystalline transformations reversible polymorphs