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Formation of X-shaped hydraulic fractures in deep thick glutenite reservoirs:A case study in Bohai Bay Basin,East China

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Journal of Central South University 2021年第9期28卷 2814-2829页

作者： li Zhi-chao li lian-chong WANG Shu-ren MA Shou ZHANG Zi-lin li ai-shan HUANG Bo ZHANG liao-yuan WANG Zeng-lin ZHANG Quan-sheng School of Civil Engineering Henan Polytechnic UniversityJiaozuo 454003China School of Resources and Civil Engineering Northeastern UniversityShenyang 110819China SinoFTS Petroleum Services Ltd. Beijing 100101China Oil Production Technology Research Institute Shengli Oilfield Branch CompanyDongying 257000China

Tight glutenite reservoirs are widely developed in Bohai Bay Basin,East *** are mostly huge thick and rely on hydraulic fracturing treatment for commercial *** investigate the propagation behavior of hydraulic fractures in these glutenite reservoirs,the geological feature of reservoirs in Bohai Bay Basin is studied firstly,including the reservoir vertical distribution feature and the heterogeneous ***,hydraulic fracturing treatments in block Yan 222 are carried out and the fracturing processes are monitored by the microseismic *** show the hydraulic fractures generated in the reservoirs are mostly in X *** cause of X-shaped hydraulic fractures in this study is mainly ascribed to(I)the reservoir heterogeneity and(II)the stress shadow effect of two close hydraulic fractures propagating in the same orientation,which is confirmed by the following numerical simulation and related research in *** study can provide a reference for the research on the fracturing behavior of the deep thick glutenite reservoirs.

关键词： glutenite hydraulic fracture X shape reservoir heterogeneity gravel

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满足临床合理用药之信息化教学资源的制作模式

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中国临床药理学杂志 2020年第22期36卷 3814-3817页

作者：秦志华王丽袁鹏李艾珊天津医学高等专科学校药理学教研室天津300222 天津医学高等专科学校微生物免疫教研室天津300222 天津医学高等专科学校解剖教研室天津300222 天津医学高等专科学校病理教研室天津300222

为提高医学生泛在式学习能力,增强学习的主体性、能动性、独立性,加强师生互动,提高学生的综合素质,本文建议构建以学生为主体、以患者为中心、以疾病为基础,以专业为指导的医学基础课程专业化、信息化教学资源的制作模式。

关键词：教学资源合理用药信息化

透过仪礼看皇太极时期对蒙关系以及“外藩(tulergi golo)”概念的形成

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吉林师范大学学报（人文社会科学版） 2017年第1期45卷 47-57页

作者：李善爱高丽大学民族文化研究院韩国首尔02799

随着皇太极占据了凌驾于蒙古各部之上的优势地位,以往暗示满蒙平等关系的仪礼步骤朝着突出皇太极优势地位的方向演变。后金汗与蒙古王公之间的接见礼有了更为复杂的步骤,并被划分等级。满蒙关系的变化成为"tulergi golo"一词开始拥有政... 详细信息

随着皇太极占据了凌驾于蒙古各部之上的优势地位,以往暗示满蒙平等关系的仪礼步骤朝着突出皇太极优势地位的方向演变。后金汗与蒙古王公之间的接见礼有了更为复杂的步骤,并被划分等级。满蒙关系的变化成为"tulergi golo"一词开始拥有政治含义的背景。"tulergi golo"一词后来被汉译为"外藩",并固定下来。对于tulergi golo概念与以中国为中心的天下秩序思想中派生的"藩"概念,应当在不同的背景中加以解释。即受皇太极统治时期的满蒙关系影响,后金(清)的对蒙政策与对蒙认识发生改变,这成为清代"外藩"的初步概念得以形成的背景。

关键词：入关前满蒙关系仪礼的政治作用 tulergigolo 理藩院清代外藩概念

Synergistic effect of bonding heterogeneity and phonon localization in introducing excellent thermoelectric properties in layered heteroanionic NdZnSbO material

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Journal of Energy Chemistry 2025年第1期100卷 259-272页

作者： Da Wan Shuwei Tang Shulin Bai Xiaodong li Peng ai Wanrong Guo Tuo Zheng College of Materials Science and Engineering Liaoning Technical University Faculty of Chemistry Northeast Normal University

Layered rare-earth metal oxides, harnessing the dual properties of oxides and two-dimensional layered materials, exhibit remarkable thermal stability and quantum confinement effects. Therefore, this work adopts the first-principles calculation combined with the Boltzmann transport theory to predict the thermoelectric properties of NdZnSbO compound. The coexistence of weak interlayer van der Waals interactions, robust intralayer ionic bonding, and partial covalent bonding leads to remarkable bonding heterogeneity, which engenders pronounced phonon scattering and imposes constraints on thermal transport along the out-of-plane direction. The weakened chemical bonds induced by the antibonding states, together with the rattling-like behavior of the Zn atom, culminate in the profound anharmonicity in the layered NdZnSbO compound. The weakening bond and heavy element contribute to the softness of phonon modes, which significantly diminishes the phonon group velocity. The redistribution-dominated four-phonon scattering process spans a large optical gap, which effectively reduces the lattice thermal conductivity. The NdZnSbO compound exhibits direct semiconductor characteristic with a bandgap of 0.73 e V by adopting the Heyd-Scuseria-Ernzerhof(HSE06) functional in combination with spin–orbit coupling(SOC) effect. The multi-valley feature of NdZnSbO compound augur favorably for band degeneracy, thus amplifying the power factor. Consequently, an optimal figure-of-merit(ZT) of 3.40 at 900 K is achieved for the n-type NdZnSbO compound. The present study delves deeply insights into the origins for the low thermal conductivity of NdZnSbO compound and proposes an optimization scheme to enhance overall thermoelectric performance.

关键词： Bond strength (chemical)

两个角度弹性阻抗反演在中深层含气储层预测中的应用

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石油地球物理勘探 2009年第1期44卷 87-92页

作者：李爱山印兴耀陆娜张广智中海石油研究中心北京市100027 中国石油大学(华东)地球资源与信息学院山东东营257061 中海石油有限公司上海分公司上海200030

在东营北带中深层天然气藏勘探中,由于盐膏岩目标层埋藏较深,无法获取大角度(大炮检距)信息,导致不能利用常规方法从大、中、小三个弹性阻抗数据体中提取岩性参数。为此,通过引入近似式,开展了从中、小角度两个弹性阻抗数据体中提取岩... 详细信息

在东营北带中深层天然气藏勘探中,由于盐膏岩目标层埋藏较深,无法获取大角度(大炮检距)信息,导致不能利用常规方法从大、中、小三个弹性阻抗数据体中提取岩性参数。为此,通过引入近似式,开展了从中、小角度两个弹性阻抗数据体中提取岩石物性参数的方法研究,并进行了数值试算。结果表明:文中所讨论的参数提取方法能够从模型数据中准确地提取纵、横波阻抗等岩性参数,利用该方法在研究区内进行岩性参数提取,进而开展储层预测,取得了良好的效果。

关键词：角道集弹性阻抗反演中深层气藏储层预测

小细胞肺癌组织中c-kit蛋白的表达及其原癌基因的检测

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中华肿瘤防治杂志 2007年第12期14卷 917-919页

作者：李艾珊孙蕾娜战忠利天津医学高等专科学校病理学教研室天津300222 天津医科大学附属肿瘤医院病理科天津300060

目的:探讨c-kit蛋白在小细胞肺癌(Small cell lung cancer,SCLC)组织中的表达及c-kit原癌基因第9和11号外显子突变状态,及其与临床病理特点之间的关系。方法:采用免疫组化方法检测13例手术切除SCLC组织标本中c-kit蛋白的表达,并用PCR扩... 详细信息

目的:探讨c-kit蛋白在小细胞肺癌(Small cell lung cancer,SCLC)组织中的表达及c-kit原癌基因第9和11号外显子突变状态,及其与临床病理特点之间的关系。方法:采用免疫组化方法检测13例手术切除SCLC组织标本中c-kit蛋白的表达,并用PCR扩增和基因测序的方法检测其第9和11号外显子序列。结果:c-kit蛋白的阳性表达率为69·2%(9/13)。13例SCLC组织中,1例(7·7%)c-kit基因9号外显子突变,5例(38·5%)c-kit基因11号外显子突变。突变方式有点突变和插入突变。结论:c-kit蛋白表达与SCLC发生发展密切相关,c-kit原癌基因第9和11号外显子均检测到突变,为临床靶向治疗SCLC提供依据。

关键词：癌,小细胞肺原癌基因蛋白质c-kit 突变

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能量高效的WSNs分簇路由协议

计算机工程与设计 2021年第2期42卷 324-330页

作者：王宗山丁洪伟李波李浩李艾珊云南大学信息学院云南昆明650500 复旦大学电子信息科学与技术上海200433

针对无线传感器网络中能耗不均衡、生命周期较短的问题,提出一种能量高效的分簇路由协议(GAKMDCR)。采用遗传算法优化的K-Medoids聚类方法对网络节点聚类分簇,综合考虑簇内节点的剩余能量、地理位置、担任过簇首的轮数等因素选举簇首,... 详细信息

针对无线传感器网络中能耗不均衡、生命周期较短的问题,提出一种能量高效的分簇路由协议(GAKMDCR)。采用遗传算法优化的K-Medoids聚类方法对网络节点聚类分簇,综合考虑簇内节点的剩余能量、地理位置、担任过簇首的轮数等因素选举簇首,使簇首节点分布均匀,均衡网络能耗。在稳定阶段,将轮询控制机制引入簇内通信,提高网络吞吐量。仿真结果表明,GAKMDCR协议能够有效均衡网络能耗,提高网络吞吐量,延长网络生存期。

关键词：无线传感器网络遗传算法 K-Medoids聚类路由轮询机制网络生存期

Interfacial Zn2+-solvation regulator towards reversible and stable Zn anode

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Journal of Energy Chemistry 2025年第1期100卷 684-692页

作者： Miao Zhou Xiongbin Luo Hang li shan Guo Zhuang Tong Xiaotao Zhou Xu li Zhaohui Hou Shuquan liang Guozhao Fang College of Mechanical Engineering Key Laboratory of Hunan Province for Advanced Carbon-based Functional Materials Hunan Institute of Science and Technology School of Materials Science and Engineering Key Laboratory of Electronic Packaging and Advanced Functional Materials of Hunan Province Central South University College of Materials and Metallurgy Guizhou University National Energy Metal Resources and New Materials Key Laboratory Central South University

Aqueous zinc-ion batteries （AZIBs） are fundamentally challenged by the instability of the electrode/electrolyte interface,predominantly due to irreversible zinc （Zn） deposition and hydrogen ***,the intricate mechanisms behind the electrochemical discrepancies induced by interfacial Zn2+-solvation and deposition behavior demand comprehensive *** molecules endowed with special functional groups （such as hydroxyl,carboxyl,etc.） have the potential to significantly optimize the solvation structure of Zn2+and regulate the interfacial electric double layer （EDL）.By increasing nucleation overpotential and decreasing interfacial free energy,these functional groups facilitate a lower critical nucleation radius,thereby forming an asymptotic nucleation model to promote uniform Zn ***,this study presents a pioneering approach by introducing trace amounts of n-butanol as solvation regulators to engineer the homogenized Zn （H-Zn） anode with a uniform and dense *** interfacial reaction and structure evolution are explored by in/ex-situ experimental techniques,indicating that the H-Zn anode exhibits dendrite-free growth,no by-products,and weak hydrogen evolution,in sharp contrast to the bare ***,the H-Zn anode achieves a remarkable Zn utilization rate of approximately 20% and simultaneously sustains a prolonged cycle life exceeding 500 ***,the H-Zn//NH4V4O10（NVO） full battery showcases exceptional cycle stability,retaining 95.04%capacity retention after 400 cycles at a large current density of 5 A *** study enlightens solvation-regulated additives to develop Zn anode with superior utilization efficiency and extended operational lifespan.

关键词： Aqueous zinc-ion batteries Interfacial reaction Asymptotic nucleation model Reversible and stable Zn anode

Treadmill exercise in combination with acousto-optic and olfactory stimulation improves cognitive function in APP/PS1 mice through the brain-derived neurotrophic factor-and Cygb-associated signaling pathways

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Neural Regeneration Research 2025年第9期20卷 2706-2726页

作者： Biao Xiao Chaoyang Chu Zhicheng lin Tianyuan Fang Yuyu Zhou Chuxia Zhang Jianghui shan Shiyu Chen liping li Department of Physiology and Pharmacology Health Science CenterNingbo UniversityNingboZhejiang ProvinceChina Ningbo Key Laboratory of Behavioral Neuroscience Health Science CenterNingbo UniversityNingboZhejiang ProvinceChina Key Laboratory of Addiction Research of Zhejiang Province NingboZhejiang ProvinceChina

A reduction in adult neurogenesis is associated with behavioral abnormalities in patients with Alzheimer's ***,enhancing adult neurogenesis represents a promising therapeutic approach for mitigating disease symptoms and ***,nonpharmacological interventions aimed at inducing adult neurogenesis are currently *** individual non-pharmacological interventions,such as aerobic exercise,acousto-optic stimulation,and olfactory stimulation,have shown limited capacity to improve neurogenesis and cognitive function in patients with Alzheimer's disease,the therapeutic effect of a strategy that combines these interventions has not been fully *** this study,we observed an age-dependent decrease in adult neurogenesis and a concurrent increase in amyloid-beta accumulation in the hippocampus of amyloid precursor protein/presenilin 1 mice aged 2-8 *** deposition became evident at 4 months,while neurogenesis declined by 6 months,further deteriorating as the disease ***,following a 4-week multifactor stimulation protocol,which encompassed treadmill running(46 min/d,10 m/min,6 days per week),40 Hz acousto-optic stimulation(1 hour/day,6 days/week),and olfactory stimulation(1 hour/day,6 days/week),we found a significant increase in the number of newborn cells(5'-bromo-2'-deoxyuridine-positive cells),immature neurons(doublecortin-positive cells),newborn immature neurons(5'-bromo-2'-deoxyuridine-positive/doublecortin-positive cells),and newborn astrocytes(5'-bromo-2'-deoxyuridine-positive/glial fibrillary acidic protein-positive cells).Additionally,the amyloid-beta load in the hippocampus *** findings suggest that multifactor stimulation can enhance adult hippocampal neurogenesis and mitigate amyloid-beta neuropathology in amyloid precursor protein/presenilin 1 ***,cognitive abilities were improved,and depressive symptoms were alleviated in amyloid precursor protein/presenilin 1 mice

关键词： acousto-optic stimulation adult neurogenesis Alzheimer's disease amyloid precursor protein/presenilin 1 mice amyloid-beta deposition brain cell apoptosis cognitive impairment depression-like behavior involuntary treadmill exercise olfactory stimulation serum metabolites