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红色文化在人的现代化中的情感价值分析

湖北科技学院学报 2024年第6期44卷 23-30页

作者：裴艳丽李琳娜黄冈师范学院马克思主义学院湖北黄冈438000

红色文化作为中国特色社会主义文化的核心组成部分,不仅承载着丰富的历史内涵,更在推动人的现代化进程中发挥着不可替代的作用。本文从情感价值的角度出发,探讨了红色文化在中国社会的现代化进程中的情感价值,特别强调了红色文化如何影... 详细信息

红色文化作为中国特色社会主义文化的核心组成部分,不仅承载着丰富的历史内涵,更在推动人的现代化进程中发挥着不可替代的作用。本文从情感价值的角度出发,探讨了红色文化在中国社会的现代化进程中的情感价值,特别强调了红色文化如何影响人们的情感需求、国家认同和社会凝聚力,并提出了如何更好地传承和弘扬红色文化、提高人的现代化水平的对策建议。

关键词：红色文化人的现代化情感价值

N-cadherin knock-down decreases invasiveness of esophageal squamous cell carcinoma in vitro

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World Journal of Gastroenterology 2009年第6期15卷 697-704页

作者： Ke li Wei He na lin Xin Wang Qing-Xia Fan Department of Oncology the First Affiliated Hospital Zhengzhou University Zhengzhou 450052 Henan Province China

AIM： To examine the expressions of N-cadherin and E-cadherin in specimens of 62 normal esophageal epithela, 31 adjacent atypical hyperplastic epithelia and 62 esophageal squamous cell carcinomas （ESCCs）, and to investigate the roles of N-cadherin in the invasiveness of ESCC cell line EC9706 transfected by N-cadherin shRna.METHODS： PV immunohistochemistry was used to detect the expression pattern of N-cadherin and E-cadherin in specimens of 62 normal esophageal epithelia, 31 adjacent atypical hyperplastic epithelia and 62 ESCCs. The invasiveness of ESCC line EC9706 was determined by transwell assay after EC9706 was transfected by N-cadherin shRna.RESULTS： The positive rotes of N-cadherin decreased in the carcinoma, adjacent atypical hyperplastic and normal esophageal tissues （75.8%, 61.3% and 29.0%, P 〈 0.05）, respectively, while those of E-cadherin increased （40.3%, 71.0% and 95.2%, P 〈 0.05）. The increased expression of N-cadherin and decreased expression of E-cadherin were related to invasion, differentiation, and lymph node metastasis （P 〈 0.05）. The expression level of N-cadherin decreased in the N-cadherin knocked down cells, and the invasiveness of those cells decreased significantly as well. The number of cells which crossed the basement membrane filter decreased from 123.40 ± 8.23 to 49.60 ±6.80 （P 〈 0.05）.CONCLUSION： E-cadherin and N-cadherin expression is correlated with the invasion and aggravation of ESCC. The down-regulation of N-cadherin lowers the invasiveness of EC9706 cell line.

关键词： Esophageal squamous cell carcinoma Rnai N-cadherin EC9706

UiO-66-NH_(2)nanoparticles supported on layered double hydroxides as an excellent adsorbent for levofloxacin capture

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Particuology 2024年第9期92卷 155-165页

作者： Yan li Heng lin Qiaolan Yu na Ma Wei Dai College of Geography and Environmental Sciences Zhejiang Normal UniversityJinhua321004China Key Laboratory of the Ministry of Education for Advanced Catalysis Materials College of Chemistry and Materials ScienceZhejiang Normal UniversityJinhua321004China

The adsorption performances of individual adsorbent such as UiO-66-NH_(2)and MgAl-layered double hydroxides(MgAl-LDH)toward levofloxacin(LVX)is less satisfactory due to the disappointing uptake capacity and adsorption ***,a 3D flower-like composite adsorbent prepared via iterative hydrothermal synthesis method anchoring UiO-66-NH_(2)nanoparticles onto the MgAl-LDH *** to the synergistic effects of UiO-66-NH_(2),and MgAl-LDH,the MgAl-LDH@UiO-66-NH_(2)exhibits an outstanding adsorption performance toward ***,the maximum LVX uptake capacity over MgAl-LDH@UiO-66-NH_(2)reached 268 mg/g,which was higher than that of the individual adsorption materials UiO-66-NH_(2)(41 mg/g),MgAl-LDH(140 mg/g),and some adsorbents reported in previous *** rapid adsorption process can reach equilibrium within 20 min,which conformed well to the pseudo-second-order kinetics and the Langmuir isotherm *** thermodynamic result also indicated that the adsorption was spontaneous and exothermic,simultaneous coexisting physical and chemical adsorption ***,the MgAl-LDH@UiO-66-NH_(2)still maintained excellent adsorption capacity with a slightly decrease after fifth cycle,exhibiting a remarkable reuse and stable *** work provides a highly novel strategy to prepare recyclable composite adsorbent for the LVX capture from aqueous solution.

关键词： Layered double hydroxides UiO-66-NH_(2) LVX Adsorption

Microstructure and room temperature fracture toughness of Nb-Si-based alloys with Sr addition

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Rare Metals 2024年第8期43卷 3904-3912页

作者： Yong-lin Huang li-na Jia Bin Kong Yue-ling Guo na Wang School of Materials Science and Engineering Beihang UniversityBeijing 100191China

Nb-Si-based alloys show great potential to surpass the widely used Ni-based *** element Sr is widely applied in aluminum and magnesium alloys,but reports about the effects of Sr on Nb-Si-based alloys are quite ***,Nb-Si-based alloys with nominal compositions of Nb-15Si-24Ti-4Cr-2Al-2Hf-0/0.05/0.15Sr(at%)were prepared by directional solidification and heat *** microstructural characterization and room temperature fracture toughness of Nb-Si-based alloy were systematically *** show that all these alloys consist of Nb_5Si_3 phase embedded within Nb solid solution(Nb_(ss)) *** Nb_(5)Si_(3) phase becomes refined and more discontinuous after adding minor *** for the fracture toughness,0.05 at% and 0.15 at% Sr additions do not cause significant *** discontinuous and refining mechanism of Sr element was studied,and the analysis of toughness decreasing with Sr addition reveals that the size of Nb_(ss) phase plays a crucial role in determining the fracture toughness.

关键词： Nb-Si alloy Refinement Discontinuous Fracture toughness Nb_(ss)

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重叠社区发现算法评价指标综述

计算机技术与发展 2024年第5期34卷 1-9页

作者：韩红旗徐紫燕李琳娜周则旭中国科学技术信息研究所北京100038 富媒体数字出版内容组织与知识服务重点实验室(国家新闻出版署) 北京100038

重叠社区发现算法对于理解复杂系统、发现复杂网络中隐藏的规律等具有很强的应用价值,而评价指标是算法发现高质量重叠社区的一个关键要素,算法的进步常常依赖于评价指标的进步。现有研究对非重叠社区发现算法的评价指标有较多的总结,... 详细信息

重叠社区发现算法对于理解复杂系统、发现复杂网络中隐藏的规律等具有很强的应用价值,而评价指标是算法发现高质量重叠社区的一个关键要素,算法的进步常常依赖于评价指标的进步。现有研究对非重叠社区发现算法的评价指标有较多的总结,而没有对重叠社区发现算法的评价指标进行总结。对重叠社区发现算法的评价指标进行了系统的总结和回顾,将指标分为事先知道社区结构、事先不知道社区结构和其它三大类。事先知道社区结构的评价指标包括基于混淆矩阵、基于ARI、基于NMI三个子类评价指标,事先不知道社区结构的评价指标包括基于模块度、基于密度、基于元数据三个子类评价指标,其它类主要介绍算法可扩展性评价指标。深入理解各种评价指标对于开发和优化重叠社区发现算法、在实际应用中发现高质量社区具有重要价值。

关键词：重叠社区评价指标社区发现社区结构复杂网络

Insights into sensitizing and eliciting capacity of gastric and gastrointestinal digestion products of shrimp(Penaeus vannamei)proteins in BALB/c mice

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Food Science and Human Wellness 2024年第1期13卷 339-348页

作者： Yao liu Songyi lin Kexin liu Shan Wang Wang li na Sun national Engineering Research Center of Seafood School of Food Science and TechnologyDalian Polytechnic UniversityDalian 116034China Collaborative Innovation Center of Seafood Deep Processing Dalian Polytechnic UniversityDalian 116034China

Shrimp(Penaeus vannamei)proteins have been shown an allergenic potential;however,little information is available on the sensitizing and eliciting capacity of shrimp protein digestion *** this study,a BALB/c mice model was used to explore the allergenicity of shrimp protein sample(SPS)and their gastric and gastrointestinal digestion products(GDS/GIDS).As compared with the SPS groups,the GDS/GIDS groups caused lower specific immunoglobulins(Ig E/Ig G1)levels(Plity and histopathological changes of tissues were ***,the allergenicity of digestion products cannot be eliminated and still cause systemic allergic reactions in *** study showed that the digestion products of shrimp still had high sensitizing and eliciting capacity.

关键词： Penaeus vannamei Allergenicity Digestion BALB/c mice model

Effect of Maternal DEHP Exposure on lipid Metabolism in Adult Male Rats and the Antagonistic Effect of Genistein

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Biomedical and Environmental Sciences 2024年第3期37卷 315-319页

作者： ZHANG Yun Bo li Jiang li TIAN Jie na Xiao lin Department of Environmental Hygiene Public Health CollegeHarbin Medical UniversityHarbin 150081HeilongjiangChina

lipid metabolism refers to the biochemical processes involved in synthesising,storing,utilising,and breaking down lipids in living *** are essential for various physiological functions,including energy storage,insulation,protection of organs,and the formation of cell *** in lipid metabolism can lead to a number of health issues,such as atherosclerosis,obesity,and type 2 diabetes,etc.[1].Environmental factors,genetics,and lifestyle factors are some of the factors that can contribute to the development of ***,there is a growing academic interest in the impact of environmental factors.

关键词： lipid metabolism organs

Preparation of Indium Tin Oxide films deposited by reactive evaporation at different substrate-temperature and the properties

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Optoelectronics Letters 2007年第6期3卷 438-440页

作者： li lin-na XUE Jun-ming ZHAO Ying li Yang-xian GENG Xin-hua Institute of Optoelectronic Thin Film Devices and Technique of nankai University Key Laboratory of OptoelectronicThin Film Devices and Technique of Tianfin Key Laboratory of Optoelectronic Information Science and Technology ofChinese Ministry of Education Tianjin 300071 China School of Material Science ＆ Engineering Hebei University of Technology Tianjin 300130 China

The Indium Tin Oxide films have been prepared at different substrate-temperamre on glass substrates by reactive evaporation of In-Sn alloy with an oxygen pressure of 1.3 × 10^-1Pa and a deposition rate of 10.2 nrrds. The best ITO films obtained have an electrical resistivity of 4.35 × 10^4 Ω.cm, a carrier concentration of 4,02 × 10^2o cm^-3 and a Hall mobility of 67.5 cm2wlsI. The influence of the substrate-temperamre on the structural, optical and electrical properties of the obtained films has been investigated.

关键词：薄膜生长基片电抗蒸发温度

Prox1 Suppresses Proliferation and Drug Resistance of Retinoblastoma Cells via Targeting Notch1

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Current Medical Science 2024年第1期44卷 223-231页

作者： Hong-li ZHANG na li lin DONG Hong-xia MA Mo-chi YANG Department of Ophthalmology General Hospital of Ningxia Medical UniversityYinchuan 750004China

Objective Retinoblastoma(RB)is a prevalent type of eye cancer in *** homeobox 1(Prox1)is a homeobox transcriptional repressor and downstream target of the proneural gene that is relevant in lymphatic,hepatocyte,pancreatic,heart,lens,retinal,and cancer *** goal of this study was to investigate the role of Prox1 in RB cell proliferation and drug resistance,as well as to explore the underlying Notch1 *** Human RB cell lines(SO-RB50 and Y79)and a primary human retinal microvascular endothelial cell line(ACBRI-181)were used in this *** expression of Prox1 and Notch1 mRna and protein in RB cells was detected using quantitative real time-polymerase chain reaction(RT-qPCR)and Western *** proliferation was assessed after Prox1 overexpression using the Cell Counting Kit-8 and the MTS ***-resistant cell lines(SO-RB50/vincristine)were generated and treated with Prox1 to investigate the role of Prox1 in drug *** employed pcDna-Notch1 to overexpress Notch1 to confirm the role of Notch1 in the protective function of ***,a xenograft model was constructed to assess the effect of Prox1 on RB in *** Prox1 was significantly downregulated in RB *** of Prox1 effectively decreased RB cell growth while increasing the sensitivity of drug-resistant cells to ***1 was involved in Prox1’s regulatory ***1 was identified as a target gene of Prox1,which was found to be upregulated in RB cells and repressed by increased Prox1 *** pcDna-Notch1 was transfected,the effect of Prox1 overexpression on RB was ***,by downregulating Notch1,Prox1 overexpression slowed tumor development and increased vincristine sensitivity in *** These data show that Prox1 decreased RB cell proliferation and drug resistance by targeting Notch1,implying that Prox1 could be a potential therapeutic target for RB.

关键词： Proxl Notch1 retinoblastoma cells proliferation drug resistance