检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

基于2KNTT的多项式乘法单元设计

电子学报 2024年第2期52卷 455-467页

作者：陈韬李慧琴吴艾青李伟南龙梅中国人民解放军战略支援部队信息工程大学河南郑州450000

在格基抗量子公钥密码算法的基础运算中,多项式乘法在硬件实现上消耗大量的时间.为提高实际运算性能,本文通过分析多项式乘法运算中数论变换的快速实现算法,提出一种面向CRYSTALS-Kyber算法、适应硬件实现的2n次单位根预处理型快速数论... 详细信息

在格基抗量子公钥密码算法的基础运算中,多项式乘法在硬件实现上消耗大量的时间.为提高实际运算性能,本文通过分析多项式乘法运算中数论变换的快速实现算法,提出一种面向CRYSTALS-Kyber算法、适应硬件实现的2n次单位根预处理型快速数论变换算法架构,利用小位宽数论变换的并行处理与复杂度低的计算形式来减少运算时间.整体运算架构在结合算法特殊性质后,确定了32路并行的设计模型.在此基础上,设计了一种与该架构匹配的统一化运算单元和数据读写不冲突、地址分配最优的存储单元.实验结果表明,在65 nm的互补金属氧化物半导体(CMOS)工艺下,97 ns完成一组项数为256、模数为3329的多项式乘法运算,花费108个周期,最高工作频率可达到1.1 GHz,面积时间积为20.7(kGE·μs).

关键词：格基抗量子公钥密码算法 CRYSTALS-Kyber 多项式乘法 2KNTT 硬件实现

同方期刊数据库

在线全文

学校读者我要写书评

暂无评论

积极心理学背景下提升高校心理育人实效

湖北开放职业学院学报 2024年第8期37卷 44-45,51页

作者：李慧芹宿迁学院江苏宿迁223800

心理育人作为高校综合教育教学体系的核心组成部分之一,对于预防学生的心理危机、引导高校大学生树立正向积极的价值观念,培养学生强大的心理承受能力和意志力有着极为重要的意义。在积极心理学的背景下,高校应通过构建科学的积极心理... 详细信息

心理育人作为高校综合教育教学体系的核心组成部分之一,对于预防学生的心理危机、引导高校大学生树立正向积极的价值观念,培养学生强大的心理承受能力和意志力有着极为重要的意义。在积极心理学的背景下,高校应通过构建科学的积极心理学育人体系、创设浓郁氛围的校园心理育人环境、确立积极心理育人方向和目的等对策,不断提升高校心理育人质量,为培养时代新人服务。

关键词：积极心理学高校心理育人实效

在线全文

学校读者我要写书评

暂无评论

钐对P92钢涂层组织及质量的影响

稀土 2024年第3期45卷 153-158,I0006页

作者：赵勇桃马洪浩李慧琴姜亚君任慧平内蒙古科技大学材料与冶金学院内蒙古包头014010

稀土在渗铝过程中不仅起到催渗促渗作用,还可以提升渗层的质量。通过配置不同稀土含量的渗铝剂6%Al-2%NH_(4)Cl-xSmCl_(3)-(92%-x)Al_(2)O_(3)(x为0,2%,4%,6%SmCl_(3)),凭借包埋法,采用合适的工艺条件在超超临界P92钢表面制备得到不同... 详细信息

稀土在渗铝过程中不仅起到催渗促渗作用,还可以提升渗层的质量。通过配置不同稀土含量的渗铝剂6%Al-2%NH_(4)Cl-xSmCl_(3)-(92%-x)Al_(2)O_(3)(x为0,2%,4%,6%SmCl_(3)),凭借包埋法,采用合适的工艺条件在超超临界P92钢表面制备得到不同稀土含量的涂层。利用OM、SEM对涂层进行组织观察,通过SEM的能谱分析对涂层截面元素分布进行分析,通过XRD对涂层表面进行物相分析。结果表明,无稀土元素的涂层厚度不均且涂层中存在孔洞、裂纹等缺陷;加入稀土,可不同程度增加渗层的厚度,且适量稀土可提升涂层质量。对比可知,2%稀土含量的渗层稍厚,且厚度均匀。不同涂层表面物相均为AlCrFe_(2)。此研究可为优化渗铝剂中稀土含量、制备质量较好的涂层提供数据支持。

关键词： P92 SmCl_(3) 渗铝实验涂层厚度包埋法

在线全文

学校读者我要写书评

暂无评论

102例临床应用卡瑞利珠单抗的安全性分析

中国合理用药探索 2024年第5期21卷 36-41页

作者：王勤李会琴王莹杰李佳音张柳艳姚丽鸽郑州市第三人民医院乳腺肿瘤内科郑州450000

目的:探究卡瑞利珠单抗治疗恶性肿瘤患者的用药安全性,为临床安全合理用药提供参考。方法:回顾性分析2021年3月4日~2023年10月30日期间于某院使用注射用卡瑞利珠单抗治疗的102例肿瘤患者,统计其基本资料、用药信息、联合用药情况、免疫... 详细信息

目的:探究卡瑞利珠单抗治疗恶性肿瘤患者的用药安全性,为临床安全合理用药提供参考。方法:回顾性分析2021年3月4日~2023年10月30日期间于某院使用注射用卡瑞利珠单抗治疗的102例肿瘤患者,统计其基本资料、用药信息、联合用药情况、免疫相关不良事件(irAEs)发生情况、处理措施与转归等。结果:患者年龄32~86岁;男性66例,女性36例;男女比例为11∶6;60例(58.82%)合并基础疾病,52例(50.98%)联合使用抗血管生成药物(如仑伐替尼、安罗替尼、阿帕替尼)。共49例患者发生irAEs,其中以反应性毛细血管增生症(RCCEP)最为常见,大多为G1~G2级。卡瑞利珠单抗联合抗血管生成药物可显著降低irAEs的发生率(P<0.05)。卡瑞利珠单抗治疗合并基础疾病患者的irAEs发生率高于无基础疾病的患者(P<0.05)。结论:临床应用卡瑞利珠单抗时,irAEs发生率较高,但严重程度均较轻,大多为G1~G2级,且多数在治疗后可缓解。

关键词：恶性肿瘤卡瑞利珠单抗反应性毛细血管增生症免疫相关不良事件安全性

Height and body mass index trajectories from 1975 to 2015 and prevalence of stunting,underweight and obesity in 2016 among children in Chinese cities:findings from five rounds of a national survey

在线全文

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2024年第4期20卷 404-412页

作者： Xin‑Nan Zong hui li Ya‑qin Zhang Department of Growth and Development Capital Institute of PediatricsBeijing 100020China

Background A more comprehensive assessment of growth and nutrition in children is required in China due to rapid socioeconomic *** aimed to investigate height and body mass index(BMI)trajectories from 1975 to 2015 and the prevalence of stunting and obesity in 2016 among children in Chinese *** A total of 904,263 children from birth to 6.9 years were collected from a series of nationally representative surveys in *** and BMI trajectories and prevalence of stunting,underweight,overweight and obesity were *** The average height level of Chinese urban children under 7 years presented a positive secular trend from 1975 to 2015;however,a slowing tendency occurred in 2005‒*** apparent increase was observed at the 5th,50th and 95th percentiles of BMI in urban children aged 3 years and older,with a more prominent increase at the 95th *** total prevalence of stunting and underweight under 7 years was 1.4%and 2.0%,*** total prevalence of overweight and obesity under 7 years was 12.6%and 4.3%,respectively,with 12.7%and 4.9%for boys,12.6%and 3.6%for girls,12.1%and 4.0%in urban areas and 13.1%and 4.5%in suburban rural *** The average height level of Chinese urban children has reached World Health Organization child growth standards since 2005 and presented a slowing tendency in secular trend in 2005‒*** attention and efforts and public health interventions should be urgently made to combat overweight and obesity among preschool children.

关键词： Body mass index Children Height Obesity Stunting

Cancer organoids:A platform in basic and translational research

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第2期11卷 614-632页

作者： Xin Ma qin Wang Guozheng li hui li Shouping Xu Da Pang Department of Breast Surgery Harbin Medical University Cancer HospitalHarbinHeilongjiang 150081China Sino-Russian Medical Research Center Harbin Medical University Cancer HospitalHarbinHeilongjiang 150081China Heilongjiang Academy of Medical Sciences HarbinHeilongjiang 150086China Department of Pharmacology (The State-Province Key Laboratories of Biomedicine-Pharmaceutics of China) College of Pharmacy of Harbin Medical UniversityHarbinHeilongjiang 150086China

An accumulation of previous work has established organoids as good preclinical models of human tumors,facilitating translation from basic research to clinical *** are changing the paradigm of preclinical cancer research because they can recapitulate the heterogeneity and pathophysiology of human cancers and more closely approximate the complex tissue environment and structure found in clinical tumors than in vitro cell lines and animal ***,the potential applications of cancer organoids remain to be comprehensively *** the review,we firstly describe what is currently known about cancer organoid culture and then discuss in depth the basic mechanisms,including tumorigenesis and tumor metastasis,and describe recent advances in patient-derived tumor organoids(PDOs)for drug screening and immunological ***,the present challenges faced by organoid technology in clinical practice and its prospects are *** review highlights that organoids may offer a novel therapeutic strategy for cancer research.

关键词： Drug assays Immunotherapy Mechanism research Organoids Precision medicine

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

亚洲棉主要农艺性状的遗传多样性分析

安徽农业科学 2024年第7期52卷 19-23页

作者：苗鹏飞李慧琴马亚杰张霞秦文强中国农业科学院棉花研究所/棉花生物育种与综合利用全国重点实验室河南安阳455000 三亚中国农业科学院国家南繁研究院海南三亚572000 石河子农业科学研究院新疆石河子832000

[目的]旨在通过对150份亚洲棉种质资源的7个农艺性状和5个纤维品质性状进行遗传多样性、相关性、主成分和聚类分析,以期为棉花遗传改良和种质利用提供一定的理论参考依据。[方法]选取150份亚洲棉种质资源,采用随机区组设计种植于试验田... 详细信息

[目的]旨在通过对150份亚洲棉种质资源的7个农艺性状和5个纤维品质性状进行遗传多样性、相关性、主成分和聚类分析,以期为棉花遗传改良和种质利用提供一定的理论参考依据。[方法]选取150份亚洲棉种质资源,采用随机区组设计种植于试验田,在整个生育期内调查株高、第一果枝长度、果枝数、结铃数、第一果枝节位、单铃重、衣分、上半部平均长度、整齐度指数、断裂比强度、马克隆值、伸长率12个性状,进行变异分析、相关性分析、主成分分析和聚类分析。[结果]该批棉花种质资源具有丰富的遗传多样性,12个农艺性状的变异系数从大到小依次为衣分(29.2%)、结铃数(23.0%)、第一果枝长度(22.6%)、单铃重(19.8%)、第一果枝节位(15.6%)、株高(15.5%)、果枝数(10.0%)、马克隆值(7.6%)、上半部平均长度(6.4%)、伸长率(5.7%)、断裂比强度(4.4%)和整齐度指数(2.3%);相关性分析表明,株高与第一果枝长度、果枝数、结铃数、第一果枝节位及单铃重呈显著正相关,第一果枝长度与结铃数、单铃重及衣分呈显著正相关,果枝数与结铃数呈显著正相关,单铃重与衣分呈显著正相关,衣分与伸长率呈显著正相关,上半部平均长度与断裂比强度呈显著负相关;主成分分析表明前5个主成分累计贡献率达到64.536%,第Ⅰ主成分主要和纤维品质有关,第Ⅱ主成分主要与结铃数有关,第Ⅲ和第Ⅳ主成分主要与果枝数有关,第Ⅴ主成分主要与第一果枝节位有关;通过聚类分析将150份亚洲棉种质资源在遗传距离为41.3时划分为4类,第Ⅰ类群和第Ⅳ类群的棉花材料可作为改良棉花衣分的材料加以利用,最具有代表性的材料分别为江苏常熟鸡脚棉和乐业逻西中棉1-3;第Ⅱ类群和第Ⅲ类群的棉花材料可作为株型改良的材料加以利用,最具有代表性的材料分别为河南商丘灰籽和山东惠民德平县一窝猴。[结论]该研究结合多个指标综合评价棉花种质资源,可为棉花育种工作中优良品种的选育提供理论依据。

关键词：亚洲棉种质资源农艺性状遗传多样性

Characteristics of transfer zones under the influence of preexisting faults and regional stress transformation:Wenchang A subsag,Zhujiang River Mouth Basin,northern South China Sea

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Journal of Oceanology and limnology 2024年第3期42卷 744-759页

作者： Wei li Mingyue CAO Meifang MENG Caiwei FAN hui li Jia li Wanqiu WU Ruiqing qin Xingan li Yiming liU State Key Laboratory of Deep Oil and Gas China University of Petroleum(East China)Qingdao 266580China School of Geosciences China University of Petroleum(East China)Qingdao 266580China Zhanjiang Branch China National Offshore Oil Corporation CompanyZhanjiang 524057China

A transfer zone in rift basins preserves important information on regional tectonic evolution and plays significant roles in hydrocarbon *** on the systematic analysis of 3D seismic data and hydrocarbon accumulation conditions,the geometry,kinematics,and reservoir control of a large synthetic overlapping transfer zone in the south of the Wenchang A subsag in the Zhujiang(Pearl)River Mouth basin were *** indicate that the development and evolution of the transfer zone was controlled by the interaction between pre-existing faults and regional stress *** intense rifting of the main faults of the transfer zone controlled the development of source rocks and faultcontrolled slope break *** strike-slip overprint since the Oligocene is conducive to the formation of a large-scale fault-anticline trap,and the secondary faults in the transfer zone contribute to the hydrocarbon *** conjugate intersection area of the NE-and NW-trending faults offers more opportunity for hydrocarbon migration and accumulation.

关键词： transfer zone pre-existing fault regional stress transformation Cenozoic Wenchang A Subsag Zhujiang(Pearl)River Mouth Basin

Associative Tasks Computing Offloading Scheme in Internet of Medical Things with Deep Reinforcement Learning

在线全文

学校读者我要写书评

暂无评论

China Communications 2024年第4期21卷 38-52页

作者： Jiang Fan qin Junwei liu Lei Tian hui School of Communications and Information Engineering Xi’an University of Posts and TelecommunicationsXi’an 710121China State Key Laboratory of Networking and Switching Technology Beijing University of Posts and TelecommunicationsBeijing 100876China

The Internet of Medical Things(Io MT) is regarded as a critical technology for intelligent healthcare in the foreseeable 6G era. Nevertheless, due to the limited computing power capability of edge devices and task-related coupling relationships, Io MT faces unprecedented challenges. Considering the associative connections among tasks, this paper proposes a computing offloading policy for multiple-user devices(UDs) considering device-to-device(D2D) communication and a multi-access edge computing(MEC)technique under the scenario of Io MT. Specifically,to minimize the total delay and energy consumption concerning the requirement of Io MT, we first analyze and model the detailed local execution, MEC execution, D2D execution, and associated tasks offloading exchange model. Consequently, the associated tasks’ offloading scheme of multi-UDs is formulated as a mixed-integer nonconvex optimization problem. Considering the advantages of deep reinforcement learning(DRL) in processing tasks related to coupling relationships, a Double DQN based associative tasks computing offloading(DDATO) algorithm is then proposed to obtain the optimal solution, which can make the best offloading decision under the condition that tasks of UDs are associative. Furthermore, to reduce the complexity of the DDATO algorithm, the cacheaided procedure is intentionally introduced before the data training process. This avoids redundant offloading and computing procedures concerning tasks that previously have already been cached by other UDs. In addition, we use a dynamic ε-greedy strategy in the action selection section of the algorithm, thus preventing the algorithm from falling into a locally optimal solution. Simulation results demonstrate that compared with other existing methods for associative task models concerning different structures in the Io MT network, the proposed algorithm can lower the total cost more effectively and efficiently while also providing a tradeoff between delay and energy co

关键词： associative tasks cache-aided procedure double deep Q-network Internet of Medical Things(IoMT) multi-access edge computing(MEC)