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High Power Quasi-Continuous-Wave Diode-End-Pumped Nd:YAG Slab Amplifier at 1319 nm

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Chinese Physics Letters 2013年第7期30卷 79-83页

作者： ZHENG Jian-Kui BO Yong XIE Shi-Yong ZUO Jun-Wei WANG Peng-Yuan GUO Ya-Ding LIU Biao-Long PENG Qin-Jun CUI Da-Fu lei wen-qiang XU Zu-Yan RCLPT Key Lab of Functional Crystal and Laser TechnologyTechnical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190 The University of Chinese Academy of Sciences Beijing 100190

We report a high power high beam quality quasi-continuous-wave(QCW)diode-end-pumped Nd:YAG slab amplifier at 1319 *** strongest 1064 nm parasitic oscillation has been successfully suppressed by reasonable coating *** a five-pass configuration,the amplifier yields a 42.3 W linearly polarized 1319 nm output at repetition rate of 1 kHz with pulse duration of 75μs and beam quality factors of M^(2)_(x)=1.13 and M^(2)_(y)=2.16 in the orthogonal *** fluctuation of the amplifier output power is measured to be±0.6%.Furthermore,a computational model of QCW pulse amplification is employed to examine the amplification process.

关键词： Nd:YAG amplifier pumped

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径向非均匀磁场下的磁控管工作性能模拟

强激光与粒子束 2005年第9期17卷 1409-1413页

作者：陈彦杨中海雷文强电子科技大学物理电子学院高能电子学研究所四川成都610054 中国工程物理研究院应用电子学研究所四川绵阳621900

为了改善磁控管的输出频谱,使模拟结构更接近实际情况,考虑了磁钢和极靴的实际尺寸。用MAFIA对磁控管内的磁系统进行建模和模拟。得到的磁场纵向分布有随着径向半径的增大而增大的趋势,这种径向不均匀性与实验测试结果一致。将非均匀的... 详细信息

为了改善磁控管的输出频谱,使模拟结构更接近实际情况,考虑了磁钢和极靴的实际尺寸。用MAFIA对磁控管内的磁系统进行建模和模拟。得到的磁场纵向分布有随着径向半径的增大而增大的趋势,这种径向不均匀性与实验测试结果一致。将非均匀的径向阶梯形变化磁场分布带入腔体热测计算,模拟得到的π模工作频率2.437 GHz,实际工作频率2.450 GHz,相对偏差0.5%,并在高频谐波的抑制上获得了输出频谱的显著改善,使微波炉磁控管具有更好的电磁防护和实际应用。

关键词：磁控管径向非均匀性磁场腔体热测计算 π模频率电磁防护

二次谐波回旋行波管Cusp电子枪的模拟与实验研究

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强激光与粒子束 2007年第1期19卷 107-111页

作者：雷文强赵军平张恩官赵军中国工程物理研究院应用电子学研究所四川绵阳621900 宽达微波通讯公司成都611731

利用3D PIC软件和乌克兰开发的电子光学计算软件TAU对二次谐波回旋行波管Cusp电子枪进行模拟,提取电子的3维运动速度计算横纵速度比。在阳极电压和阴极电流变化的条件下,对电子速度比和速度零散随之而变化的情况进行了模拟,得到平均速度... 详细信息

利用3D PIC软件和乌克兰开发的电子光学计算软件TAU对二次谐波回旋行波管Cusp电子枪进行模拟,提取电子的3维运动速度计算横纵速度比。在阳极电压和阴极电流变化的条件下,对电子速度比和速度零散随之而变化的情况进行了模拟,得到平均速度比1.1和平均速度零散9.5%的结果。基于电子平均半径,并根据电子平均半径与横向速度、纵向速度的关系提出了一种实验测量速度比的方法。当电子轰击荧光屏玻璃时,玻璃上的荧光物质感应到光斑,测量空心光斑的平均半径可计算得到电子速度比,其结果与模拟值误差15%。

关键词：二次谐波回旋行波管 Cusp电子枪 3D PIC软件 TAU软件速度比速度零散

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智能电能表技术及其运行管理方案研究

电力系统装备 2021年第13期 177-178页

作者：温磊强国网邯郸市永年区供电公司河北邯郸057150

随着我国科学技术的不断进步,智能电网也随之发展,智能电能表的重要性不断提升,且得到了广泛的运用。智能电能表是科学发展进步的要求,同时也代表了社会生活发展的必然趋势,在用电信息采集与用电计算方面发挥了重要的作用。智能电能表... 详细信息

随着我国科学技术的不断进步,智能电网也随之发展,智能电能表的重要性不断提升,且得到了广泛的运用。智能电能表是科学发展进步的要求,同时也代表了社会生活发展的必然趋势,在用电信息采集与用电计算方面发挥了重要的作用。智能电能表技术替代了传统的人工抄表,采用信息采集、网络技术、电量监控等技术,实现了全自动化管理,节省了人力物力,大大提高了电网的工作效率,是电网现代化的里程碑式的进步。

关键词：智能电能表运行管理方案研究

Effects of the extrusion parameters on microstructure,texture and room temperature mechanical properties of extruded Mg-2.49Nd-1.82Gd-0.2Zn-0.2Zr alloy

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 136-146页

作者： Chenjin Zhang Guangyu Yang lei Xiao Zhiyong Kan Jing Guo qiang Li Wanqi Jie State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China College of Materials Science and Engineering Fuzhou UniversityFuzhou 350108China College of Chemistry and Environmental Science Qujing Normal UniversityQujing 655011China

Microstructure,texture,and mechanical properties of the extruded Mg-2.49Nd-1.82Gd-0.2Zn-0.2Zr alloy were investigated at different extrusion temperatures(260 and 320℃),extrusion ratios(10:1,15:1,and 30:1),and extrusion speeds(3 and 6 mm/s).The experimental results exhibited that the grain sizes after extrusion were much finer than that of the homogenized alloy,and the second phase showed streamline distribution along the extrusion direction(ED).With extrusion temperature increased from 260 to 320℃,the microstructure,texture,and mechanical properties of alloys changed *** dynamic recrystallization(DRX)degree and grain sizes enhanced as the extrusion ratio increased from 10:1 to 30:1,and the strength gradually decreased but elongation(EL)*** the extrusion speed increased from 3 to 6 mm/s,the grain sizes and DRX degree increased significantly,and the samples presented the typical-rare-earth(RE)*** alloy extruded at 260℃ with extrusion ratio of 10:1 and extrusion speed of 3 mm/s showed the tensile yield strength(TYS)of 213 MPa and EL of 30.6%.After quantitatively analyzing the contribution of strengthening mechanisms,it was found that the grain boundary strengthening and dislocation strengthening played major roles among strengthening *** results provide some guidelines for enlarging the industrial application of extruded Mg-RE alloy.

关键词： Mg-rare earth alloys extrusion temperature extrusion ratio extrusion speed strengthening mechanisms

MAFIA在行波管多级降压收集极模拟中的应用

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电子与信息学报 2005年第3期27卷 483-486页

作者：廖平杨中海李斌雷文强廖莉高迅鸿电子科技大学物理电子学院成都610054

评述了传统二维稳态轨迹程序模拟多级降压收集极计算方法,同时提出了使用MAFIA+大信号分析软件对多级降压收集极进行全三维动态PIC模拟的方法和收集极效率简化计算公式。初步模拟实例表明该方法与实验结果吻合较好,为收集极的精确模拟... 详细信息

评述了传统二维稳态轨迹程序模拟多级降压收集极计算方法,同时提出了使用MAFIA+大信号分析软件对多级降压收集极进行全三维动态PIC模拟的方法和收集极效率简化计算公式。初步模拟实例表明该方法与实验结果吻合较好,为收集极的精确模拟和优化设计提供了新的途径。同时也指出了该方法存在的不足。

关键词：多级降压收集极行波管粒子模拟 MAFIA软件计算机辅助设计

The potential mechanism and clinical application value of remote ischemic conditioning in stroke

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Neural Regeneration Research 2025年第6期20卷 1613-1627页

作者： Yajun Zhu Xiaoguo Li Xingwei lei Liuyang Tang Daochen wen Bo Zeng Xiaofeng Zhang Zichao Huang Zongduo Guo The First Affiliated Hospital of Chongqing Medical University ChongqingChina

Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may be related to neuroinflammation, cellular immunity, apoptosis, and autophagy, the exact underlying molecular mechanisms are unclear. This review summarizes the current status of different types of remote ischemic conditioning methods in animal and clinical studies and analyzes their commonalities and differences in neuroprotective mechanisms and signaling pathways. Remote ischemic conditioning has emerged as a potential therapeutic approach for improving stroke-induced brain injury owing to its simplicity, non-invasiveness, safety, and patient tolerability. Different forms of remote ischemic conditioning exhibit distinct intervention patterns, timing, and application range. Mechanistically, remote ischemic conditioning can exert neuroprotective effects by activating the Notch1/phosphatidylinositol 3-kinase/Akt signaling pathway, improving cerebral perfusion, suppressing neuroinflammation, inhibiting cell apoptosis, activating autophagy, and promoting neural regeneration. While remote ischemic conditioning has shown potential in improving stroke outcomes, its full clinical translation has not yet been achieved.

关键词： Akt apoptosis autophagy cerebral perfusion cerebral vascular stenosis clinical transformation hemorrhagic stroke ischemic stroke neuroinflammation neuroprotection Notch1 PI3K remote ischemic conditioning stroke

BIBR1532 inhibits proliferation and metastasis of esophageal squamous cancer cells by inducing telomere dysregulation

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 214-225页

作者： Qin Wang Qing-Rong Li lei Xu Zi-Chun Yuan Xiao Liu Mao-Ju Tang Man Luo Xiao-Wu Zhong qiang Ma Xiao-Lan Guo Department of Clinical Laboratory Affiliated Hospital of North Sichuan Medical CollegeNanchong 637000Sichuan ProvinceChina School of Laboratory Medicine&Translational Medicine Research Center North Sichuan Medical CollegeNanchong 637000Sichuan ProvinceChina

BACKGROUND Esophageal squamous cell carcinoma(ESCC)is a malignant tumor with high morbidity and mortality,and easy to develop resistance to chemotherapeutic *** are DNA-protein complexes located at the termini of chro-mosomes in eukaryotic cells,which are unreplaceable in maintaining the stability and integrity of ***,an RNA-dependent DNA polymerase,play vital role in telomere length maintain,targeting telomerase is a promising therapeutic strategy for ***150 and KYSE410 cells were cultured and exposed to various concentrations of *** viability was assessed at 48 hours and 72 hours to determine the IC50 *** effects of BIBR1532 on ESCC cell proliferation,migration,and cellular senescence were evaluated using the cell counting kit-8 assay,plate colony formation assay,scratch assay,transwell assay,andβ-galactosidase staining,*** blotting was performed to detect the expression of RESULTS The IC50 values for KYSE150 and KYSE410 cells after 48 hours of BIBR1532 exposure were 48.53μM and 39.59μM,*** values decreased to 37.22μM and 22.71μM,respectively,following a longer exposure of 72 ***1532 exhibited dose-dependent effects on KYSE150 and KYSE410 cells,including decreased hTERT expression,inhibition of proliferation and metastasis,and induction of cellular ***,BIBR1532 upregulated the expression of the DDR protein,γ-H2AX,and activated the ataxia telangiectasia and Rad3-related protein(ATR)/check point kinase 1(CHK-1)and ataxia-telangiectasia mutated gene(ATM)/CHK2 ***1532 downregulated the expression of telomere-binding proteins,including telomeric-repeat binding factor 1(TRF1),TRF2,protection of telomeres 1,and TIN2-interacting protein *** a nude mouse xenograft model,BIBR1532 significantly suppressed tumor growth,reduced hTERT expression,and increasedγ-H2AX protein *** and eosin staining of various organs,including the heart,liver,s

关键词： Esophageal squamous cell carcinoma BIBR1532 Human telomerase reverse transcriptase DNA damage response Telomere-binding proteins

毫米波/太赫兹扩展互作用速调管放大器的应用及研究进展

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电子学报 2019年第1期47卷 211-219页

作者：胡林林曾造金陈洪斌马国武雷文强孟凡宝中国工程物理研究院应用电子学研究所四川绵阳621900

作者对毫米波与太赫兹频段的扩展互作用速调管放大器的应用需求和发展现状进行了详细的调研,介绍了该器件在空间探测、主动拒止、生物医学等研究领域的应用,说明了该器件在毫米波及太赫兹技术研究中的科学价值和良好的应用前景;同时,作... 详细信息

作者对毫米波与太赫兹频段的扩展互作用速调管放大器的应用需求和发展现状进行了详细的调研,介绍了该器件在空间探测、主动拒止、生物医学等研究领域的应用,说明了该器件在毫米波及太赫兹技术研究中的科学价值和良好的应用前景;同时,作者对该器件的发展趋势、主要技术难点和遇到的挑战进行了分析.

关键词：扩展互作用速调管分布作用速调管太赫兹