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Variability and trends of near-surface wind speed over the Tibetan Plateau:The role played by the westerly and Asian monsoon

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Advances in Climate Change Research 2024年第3期15卷 525-536页

作者： Gang-Feng ZHANG Cesar AZORIN-MOLINA Deliang CHEN tim RMCVICAR Jose AGUIJARRO Kai-Qiang DENG Lorenzo MINOLA Jaeyeon lee Seok-Woo SON Heng MA Pei-Jun SHI State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal UniversityBeijing 100875China Engineering Center of Desertification and Blown-Sand Control of Ministry of Education Faculty of Geographical ScienceBeijing Normal UniversityBeijing 100875China Key Laboratory of Environmental Change and Natural Disaster of Ministry of Education Beijing Normal UniversityBeijing 100875China Centro de Investigaciones Sobre Desertificaci'on Consejo Superior de Investigaciones Cientı'ficas(CIDECSIC-UV-Generalitat alenciana)ClimateAtmosphere and Ocean Laboratory(Climatoc-Lab)Moncada 46113Spain Regional Climate Group Department of Earth SciencesUniversity of GothenburgGothenburg 40530Sweden CSIRO Environment CanberraACT 2600Australia Australian Research Council Centre of Excellence for Climate Extremes CanberraACT 2600Australia State Meteorological Agency Balearic Islands OfficePalma de Mallorca 07015Spain School of Atmospheric Sciences Sun Yat-sen UniversityZhuhai 519082China Interuniversity Department of Regional and Urban Studies and Planning(DIST) Politecnico and University of TurinTurin 10125Italy School of Earth and Environmental Sciences Seoul National UniversitySeoul 08826South Korea Atmospheric and Oceanic Sciences Program Princeton UniversityPrinceton NJ 08544USA Geophysical Fluid Dynamics Laboratory NOAAPrinceton NJ 08544USA

Near-surface wind speed exerts profound impacts on many environmental issues,while the long-term(≥60 years)trend and multidecadal variability in the wind speed and its underlying causes in global high-elevation and mountainous areas(e.g.,Tibetan Plateau)remain largely ***,by examining homogenized wind speed data from 104 meteorological stations over the Tibetan Plateau for 1961-2020 and ERA5 reanalysis datasets,we investigated the variability and long-term trend in the near-surface wind speed and revealed the role played by the westerly and Asian *** results show that the homogenized annual wind speed displays a decreasing trend(-0.091 m s^(−1)per decade,p<0.05),with the strongest in spring(-0.131 m s^(−1)per decade,p<0.05),and the weakest in autumn(-0.071 m s^(−1)per decade,p<0.05).There is a distinct multidecadal variability of wind speed,which manifested in an prominent increase in 1961-1970,a sustained decrease in 1970-2002,and a consistent increase in *** observed decadal variations are likely linked to large-scale atmospheric circulation,and the correlation analysis unveiled a more important role of westerly and East Asian winter monsoon in modulating near-surface wind changes over the Tibetan *** potential physical processes associated with westerly and Asian monsoon changes are in concordance with wind speed change,in terms of overall weakened horizontal air flow(i.e.,geostrophic wind speed),declined vertical thermal and dynamic momentum transfer(i.e.,atmospheric stratification thermal instability and vertical wind shear),and varied Tibetan Plateau *** indicates that to varying degrees these processes may have contributed to the changes in near-surface wind speed over the Tibetan *** study has implications for wind power production and soil wind erosion prevention in the Tibetan Plateau.

关键词： Tibetan Plateau Wind speed Decadal change Atmospheric circulation Physical processes

Impact of Renewable Energy Sources on Steady-state Stability of Weak AC/DC Systems

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CSEE Journal of Power and Energy Systems 2017年第4期3卷 419-430页

作者： Denis lee hau Aik Göran Andersson Sarawak Electricity Supply Corporation SarawakMalaysia Swiss Federal Institute of Technology ETHZürichSwitzerland

In recent years,the penetration of renewable resources into AC power systems has increased tremendously,creating a significantly impact on the latter’s operations and *** this respect,it is also important to gain a basic analytical understanding of such impact on the steady-state stability of power systems with electrically weak AC/DC interconnections,but such works are not very evident in the ***,a classical analytic model of the single and multi-infeed HVDC system which now incorporates renewable resources is *** the well-established concept of voltage sensitivity of the AC/DC interconnection is applied to analyze the impact of the renewable resources on the steady-state stability of these composite system models,as well as on the influence of system conditions and *** impact is also compared with that arising from other types of shunt devices alternatively connected at the same AC/DC interconnection,therefore their relative beneficial or negative impacts will also be benchmarked.

关键词： Single and multi-infeed HVDC system model incorporating renewable sources steady-state stability voltage sensitivity method weak AC/DC interconnection

Assembly of a parts list ofthe human mitotic cell cycle machinery

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Journal of Molecular Cell Biology 2019年第8期11卷 703-718页

作者： Bruno Giott Sz-hau Chen Mark W.Barnett tim Regan Tony Ly Stefan Wiemann David A.Hume Tom C.Freeman The Roslin Institute University of Edinburgh Easter Bush Midlothian EH25 9RG Scotland UK Biosciences and Biotechnology Institute EDyP Department CEA Grenoble 17 rue des Martyrs 38054 Grenoble France Wellcome Centre for Cell Biology University of Edinburgh Swann Building Edinburgh EH9 3BF Scotland UK Molecular Genome Analysis (B050) Deutsches Krebsforschungszentrum Im Neuenheimer Feld 580 69120 Heidelberg Germany Mater Research Institute University of Queensland Level 3 Aubigny Place Raymond Terrace South Brisbane Qld 4101 Australia

The set of proteins required for mitotic division remains poorly characterized. Here, an extensive series of correlation analyses of human and mouse transcriptomics data were performed to identify genes strongly and reproducibly associated with cells undergoing S/G2-M phases of the cell cycle. In so doing, 701 cell cycle-associated genes were defined and while it was shown that many are only expressed during these phases, the expression of others is also driven by alternative promoters. Of this list, 496 genes have known cell cycle functions, whereas 205 were assigned as putative cell cycle genes, 53 of which are functionally uncharacterized. Among these, 27 were screened for subcellular localization revealing many to be nuclear localized and at least three to be novel centrosomal proteins. Furthermore, 10 others inhibited cell proliferation upon siRNA knockdown. This study presents the first comprehensive list of human cell cycle proteins, identifying many new candidate proteins.

关键词： cell cycle systems biology gene expression transcriptome network analysis

CT Brain Image:Abnormalities Recognition and Segmentation

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Journal of Donghua University(English Edition) 2010年第2期27卷 246-249页

作者： TONG hau-lee Mohammad Faizal Ahmad Fauzi Ryoichi Komiya HAW Su-Cheng Faculty of Information Technology Multimedia UniversityJalan Multimedia Faculty of Engineering Multimedia UniversityJalan Multimedia

In order to develop an automated segmentation system for Computed Tomography （CT） brain images, a new approach which consists of several unsupervised segmcotation techniques was introduced. The system segments the CT brain images into three partitions, i. e., abnormalities, cerebrospinal fluid （CSF）, and brain matter. Our approach consists of two phase-segmentation methods. In the first phase segmentation, k-means and fuzzy cmeans （FCM） methods were implemented to segment and transform the images into the binary images. Based on the connected component in binary images, a decision tree was employed for the annotation of normal or abnormal regions. In the second phase segmentation, the modified FCM with population-diameter independent （PDI） segmentation was applied to segment the images into CSF and brain matter. The experimental results have shown that our proposed system is feasible and yield satisfactory results.

关键词： computed tomography ursupervised segmentation k-means fuzzy c-means population-diameter indepentdent

Supply chain and logistics innovations with the Belt and Road Initiative

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Journal of Management Science and Engineering 2020年第2期5卷 77-86页

作者： hau Llee Zuo-Jun(Max)Shen Graduate School of Business Stanford UniversityStanfordCA94305-5015USA Department of Industrial Engineering and Operations Research and Department of Civil and Environmental EngineeringUniversity of CaliforniaBerkeleyCA94720USA

The Belt and Road Initiative(BRI)is a massive,ambitious,long-term project initiated by the Chinese government,with participation from many other countries,to facilitate trade and improve logistics in an effort to promote global economic *** this paper,we identified the supply chain and logistics innovations linked to the *** innovations include new routes and modes for global trade,new supply chain design,reduction of cross-border logistics frictions,and entrepreneurial *** of some of these innovations are emerging,while new ones are being *** innovations can enable businesses to improve their operational performances and create economic *** the same time,to realize the full potentials of BRI,new work processes and technologies,incentive alignment,collaborations among businesses,and optimized plan-ning are *** provides great opportunities for researchers to explore how to overcome barriers and achieve the full values of BRI.

关键词： Belt and road initiative Supply chain management Logistics

New insights into carbon-based and MXene anodes for Na and K-ion storage: A review

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Journal of Energy Chemistry 2021年第11期30卷 660-691,I0016页

作者： Zhensheng Hong Hajar Maleki tim Ludwig Yichao Zhen Michael Wilhelm Damin lee Kwang-Ho Kim Sanjay Mathur Fujian Provincial Key Laboratory of Quantum Manipulation and New Energy Materials College of Physics and EnergyFujian Normal UniversityFuzhou 350117FujianChina Institute of Inorganic Chemistry University of CologneGreinstr.650939 CologneGermany Fujian Provincial Collaborative Innovation Center for Advanced High-Field Superconducting Materials and Engineering Fuzhou 350117FujianChina Global Frontiers of Hybrid Interfacial Materials Pusan National UniversitySouth Korea

Na-ion batteries and K-ion batteries are promising alternatives to vastly used lithium-ion batteries mainly due to the larger natural abundance of sodium and potassium resources. Carbon-based and MXene materials have received increasing attention due to their unique layered structure to accommodate the larger sodium and potassium ions. It’s proposed that ionic size disparity (K^(+): 1.38 Å;Na^(+): 0.97 Å;Li^(+): 0.76 Å) leads to sluggish intercalation and extraction kinetics in larger alkali metal ions (AMIs). Nevertheless, the electrochemical inactivity of sodium intercalation in graphite suggests that different chemical properties of AMs and their interactions with carbon host and electrolytes is crucial for interfacial instability and irreversible capacity loss. Structural modifications by expanding interlayer spacing and defect engineering enable reduced diffusion barriers and enhanced insertion of sodium or potassium, but it blurs the electrochemical performance between battery and capacitor. This review provides insight into 2D carbon materials and their architectures for Na and K-ion batteries through an in-depth analysis of structure–property interdependence and different electrochemical mechanisms supported by both experimental and theoretical data to discuss the promises and challenges of post-lithium batteries. Finally, the perspectives and potential directions regarding material design concepts for 2D carbon-based nanomaterials and MXene phases for metal-ion storage are proposed.

关键词： Na-ion batteries K-ion batteries Anode Carbon materials Structure design

Prediction of early-stage hepatocellular carcinoma using Onco Scan chromosomal copy number aberration data

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World Journal of Gastroenterology 2017年第44期23卷 7818-7829页

作者： Ming-Chin Yu Chao-Wei lee Yun-Shien lee Jang-hau Lian Chia-Lung Tsai Yi-Ping Liu Chun-Hsing Wu Chi-Neu Tsai Department of Surgery Chang Gung Memorial Hospital Department of Surgery Xiamen Chang Gung Hospital Graduate Institute of Clinical Medical Sciences Chang Gung University Genomic Medicine Core Laboratory Chang Gung Memorial Hospital Department of Biotechnology Ming-Chuan University Department of Pediatrics Chang Gung Memorial Hospital

AIM To identify chromosomal copy number aberrations(CNAs) in early-stage hepatocellular carcinoma(HCC) and analyze whether they are correlated with patient *** One hundred and twenty patients with early-stage HCC were enrolled in our study, with the collection of formalin fixed, paraffin-embedded(FFPE) specimens and clinicopathological data. Tumor areas were marked by certified pathologists on a hematoxylin and eosinstained slide, and cancer and adjacent non-cancerous tissues underwent extraction of DNA, which was analyzed with the Affymetrix Onco Scan platform to assess CNAs and loss of heterozygosity(LOH). Ten individuals with nonmalignant disease were used as the control group. Another cohort consisting of 40 patients with stage Ⅰ/Ⅱ HCC were enrolled to analyze gene expression and to correlate findings with the Onco Scan *** Copy number amplifications occurred at chromosomes 1 q21.1-q44 and 8 q12.3-24.3 and deletions were found at 4 q13.1-q35.2, 8 p 23.2-21.1, 16 q23.3-24.3, and 17 p13.3-12, while LOH commonly occurred at 1 p32.3, 3 p21.31, 8 p23.2-21.1, 16 q22.1-24.3, and 17 p 13.3-11 in early-stage HCC. Using Cox regression analysis, we also found that a higher percentage of genome change(≥ 60%) was an independent factor for worse prognosis in early-stage HCC(P = 0.031). Among the 875 genes in the Onco Scan Gene Chip, six were independent predictors of worse disease-free survival, of which three were amplified(MYC, ELAC2, and SYK) and three were deleted(GAK, MECOM, and WRN). Further, patients with HCC who exhibited ≥ 3 CNAs involving these six genes have worse outcomes compared to those who had < 3 CNAs(P < 0.001). Similarly, Asian patients with stage I HCC from The Cancer Genome Atlas harboring CNAs with these genes were also predicted to have poorer *** Patients with early-stage HCC and increased genome change or CNAs involving MYC, ELAC2, SYK, GAK, MECOM, or WRN are at risk for poorer outcome after resection.

关键词： Early-stage hepatocellular carcinoma Copy number aberration Prognosis Onco Scan Molecular inversion probe

VETA:Visual eye-tracking analytics for the exploration of gaze patterns and behaviours

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Visual Informatics 2022年第2期6卷 1-13页

作者： Sarah Goodwin Arnaud Prouzeau Ryan Whitelock-Jones Christophe Hurter lee Lawrence Umair Afzal tim Dwyer Monash University ClaytonAustralia Inria&LaBRI(University of Bordeaux CNRSBordeaux-INP)BordeauxFrance ENAC UniversitédeToulouseToulouseFrance Swinburne University of Technology MelbourneAustralia

Eye tracking is growing in popularity for multiple application areas,yet analysing and exploring the large volume of complex data remains difficult for most *** present a comprehensive eye tracking visual analytics system to enable the exploration and presentation of eye-tracking data across time and space in an efficient *** application allows the user to gain an overview of general patterns and perform deep visual analysis of local gaze *** ability to link directly to the video of the underlying scene allows the visualisation insights to be verified on the *** system was motivated by the need to analyse eye-tracking data collected from an‘in the wild’study with energy network operators and has been further evaluated via interviews with 14 eye-tracking experts in multiple *** suggest that,thanks to state-of-the-art visualisation techniques and by providing context with videos,our system could enable an improved analysis of eye-tracking data through interactive exploration,facilitating comparison between different participants or conditions,thus enhancing the presentation of complex data analysis to *** research paper provides four contributions:(1)analysis of a motivational use case demonstrating the need for rich visual-analytics workflow tools for eye-tracking data;(2)a highly dynamic system to visually explore and present complex eye-tracking data;(3)insights from our applied use case evaluation and interviews with experienced users demonstrating the potential for the system and visual analytics for the wider eye-tracking community.

关键词： Eye tracking Visual analytics Spatial-temporal visualisation

Techno-Economic and Sustainability Analysis of Potential Cooling Methods in Irish Data Centres

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Journal of Electronics Cooling and Thermal Control 2021年第3期10卷 35-54页

作者： lee Gibbons tim Persoons Sajad Alimohammadi School of Mechanical and Design Engineering Technological University Dublin Dublin Ireland Department of Mechanical Manufacturing & Biomedical Engineering Trinity College Dublin Dublin Ireland

11% of Irish electricity was consumed by data centres in 2020. The Irish data centre industry and the cooling methods utilised require reformative actions in the coming years to meet EU Energy policies. The resell of heat, alternative cooling methods or carbon reduction methods are all possibilities to conform to these policies. This study aims to determine the viability of the resell of waste heat from data centres both technically and economically. This was determined using a novel application of thermodynamics to determine waste heat recovery potential in Irish data centres, and the current methods of heat generation for economical comparison. This paper also explores policy surrounding waste heat recovery within the industry. The Recoverable Carnot Equivalent Power (RCEP) is theoretically calculated for the three potential cooling methods for Irish data centres. These are air, hybrid, and immersion cooling techniques. This is the maximum useable heat that can be recovered from a data centre rack. This study is established under current operating conditions which are optimised for cooling performance, that air cooling has the highest potential RCEP of 0.39 kW/rack. This is approximately 8% of the input electrical power that can be captured as useable heat. Indicating that Irish data centres have the energy potential to be heat providers in the Irish economy. This study highlighted the technical and economic aspects of prevalent cooling techniques and determined air cooling heat recovery cost can be reduced to 0.01 €/kWhth using offsetting. This is financially competitive with current heating solutions in Ireland.

关键词： Ireland Data Centres Techno-Economic Novel Cooling Methods Heat Resell Sustainability Energy Demand