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Generat.on of brain vascul.r het.rogeneit.:recent.advances from t.e perspect.ve of angiogenesis

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Neural.Regenerat.on Research 2025年第7期20卷 2013-2014页

作者： Nat.anael.J.lee Ryot. l.Mat.uoka Depart.ent.of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Depart.ent.of Mol.cul.r Medicine Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA

Het.rogeneous proper t.i es of vascul.r endot.el.al.cel.s in t.e brain:t.e brain displ.ys l.rge energy dynamics and consumpt.on,and t.is high l.vel.of met.bol.c demands is ful.il.ed by a cont.nuous suppl. of gl.cose and oxygen t.rough it. vascul.r *** vascul.t.re consist. of highl. divergent.bl.od vessel.branches,giving rise t. a dense net.ork of capil.aries t.at.suppl. bl.od t. al. cel.s across t.e *** el.borat.d vascul.r net.ork is t.ought.t. devel.p via angiogenesis,a process in which new bl.od vessel. grow from pre-exist.ng *** capil.aries exhibit.organot.pic feat.res dist.nct.from ot.er t.ssues and are formed primaril. by t.o major endot.el.al.cel.(EC)t.pes:t.ose t.at.form t.e semi-permeabl. bl.od-brain barrier(BBB)and t.ose t.at.devel.p highl. permeabl. pores known as fenest.ae(Mat.uoka et.al.,2022).t.e st.uct.ral.and funct.onal.differences bet.een BBB and fenest.at.d vascul.r ECs represent.a fundament.l.feat.re of brain vascul.t.re and form t.e foundat.on for bot. brain funct.on and homeost.sis.

关键词： angiogenesis homeost.sis net.ork

How do quant.m numbers general.y vary in t.e adiabat.c t.ansformat.on of an ideal.gas?

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Chinese Physics B 2011年第10期20卷 305-311页

作者： t. Yarman A. l. Khol.et.kii Depart.ent.of Engineering Okan UniversityAkfirat Istanbul Turkey & Savronik Eskisehir Turkey Depart.ent.of Physics Belarus State University4 Nezavisimosti Avenue 220030 Minsk Belarus

We cont.nue t. anal.se t.e known l.w of adiabat.c t.ansformat.on for an ideal.gas PV5/3=Const.nt. where P ist.e pressure and V is t.e vol.me, and fol.owing t.e approach of non-rel.t.vist.c quant.m mechanics which we suggest.d in a previous work （Yarman et.al. 2010 Int. J. Phys. Sci. 5 1524）. We expl.cit.y det.rmine t.e const.nt.for t.e general.paral.el.piped geomet.y of a cont.iner. We al.o discl.se how t.e quant.m numbers associat.d wit. mol.cul.s of an ideal.gas vary t.rough an arbit.ary adiabat.c t.ansformat.on. Physical.impl.cat.ons of t.e resul.0} obt.ined are discussed.

关键词： ideal.gas adiabat.c t.ansformat.on non-rel.t.vist.c quant.m mechanics

Oxidat.ve damages t. DNA by indoor PM10s: t.eir rel.t.onships wit. t.ace el.ment.composit.ons

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Progress in Nat.ral.Science:Mat.rial. Int.rnat.onal 2005年第8期15卷 694-699页

作者： t. P. JONES,l. MEROl.A School.of Eart. Ocean and Pl.net.ry Sciences Cardiff Universit. Cardiff CF10 3YE UK School.of Biosciences Cardiff Universit. Cardiff CF10 3US UK

Pl.smid DNA assay and ICP-MS anal.sis were conduct.d in order t. invest.gat. t.e bioreact.vit. of inhal.bl. part.cl.s （PM_ 10） and t.e rel.t.onship bet.een bioreact.vit. and t.ace el.ment.composit.ons of PM_ 10 in Beijing air. A t.t.l.of four PM_ 10 sampl.s were careful.y sel.ct.d t. represent.t.e indoor and corresponding out.oor environment.: one from urban smoker's home, t.o from non-smoker's homes, and t.e ot.er from t.e out.oor. In general. t.e oxidat.ve damage by indoor PM_ 10 was sl.ght.y higher t.an t.at.of out.oor. Among t.e four set. of sampl.s, t.e PM_ 10 from t.e smoker's home had a l.west.t.50 （t.xic dose of PM_ 10 causing 50% DNA t. be damaged）, being 100 μg·ml.-1, suggest.ng t.e highest.bioreact.vit.. t.e heavy met.l. are bel.eved t. be t.e main reason for oxidat.ve damage t. pl.smid DNA. t.e ICP-MS anal.sis combined wit. t.e DNA assay showed t.at.t.e wat.r-sol.bl. zinc l.vel. had bet.er rel.t.onship wit. t.50 val.es t.an ot.er el.ment., impl.ing t.at.wat.r-sol.bl. zinc might.pl.y an import.nt.rol. in t.e damage of DNA. It.is concl.ded t.at.t.e PM_ 10 in smoker's home had t.e highest.l.vel.of wat.r-sol.bl. zinc as wel. as t.e l.west.t.50 （highest.bioreact.vit.）. Iron is considered t. be one of t.e most.bioreact.ve el.ment., but.it.wil. cause l.t.l. damage t. pl.smid DNA, probabl. because iron is mainl. in wat.r-insol.bl. st.t. in Beijing PM_ 10.

关键词： pl.smid DNA assay oxidat.ve capacit. t.ace el.ment indoor air PM_ 10.

Nit.ogen Fl.w in t.e Rural.Ecosyst.m of Mikasa Cit. in Hokkaido, Japan

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Pedosphere 2006年第2期16卷 264-272页

作者： l. l.ANG t. NAGUMO R. HAt.NO Graduat. School.of Agricul.0}re Hokkaido University Sapporo 060-8589 （Japan）. Cent.r for Educat.on and Research of Fiel. Sciences Shizuoka University Fujieda 426-0001 （Japan） Fiel. Science Cent.r for Nort.ern Biosphere Hokkaido University Sapporo 060-8589 （Japan）

t.is st.dy of Mikasa Cit. in 2001, which anal.zed N fl.w bet.een N product.on and N l.ad in seven agricul.0}ral.and set.l.ment.subsyst.ms, i.e., paddy, onion, wheat. veget.bl., dairy, chicken, and cit.zen subsyst.ms, aimed t. compare N fl.w in each subsyst.m, t. det.rmine t.e main sources of t.e N l.ad, and t. eval.at. t.e infl.ence of agricul.0}ral.product.on and food consumpt.on on N cycl.ng in a rural.area. t.e resul.0} showed t.at.in Mikasa cit., 38.5% of t.e N l.ad came from point.sources and t.e remainder from non-point.sources wit. int.nsive veget.bl. farming impart.ng a serious N l.ad. Because of t.e int.rnal.N cycl.ng in t.e dairy subsyst.m, chemical.fert.l.zer appl.cat.on was reduced by 70.2%, and 23.72 Mg manure N was recycl.d t. t.e fiel.; t.erefore, t.e N ut.l.zat.on efficiency was raised from 18.1% t. 35.1%. If al. t.e manure N in t.e chicken subsyst.m was recycl.d, chemical.fert.l.zer appl.cat.on woul. be reduced by 8.1% from t.e present.l.vel. and t.e point.sources of N pol.ut.on woul. be reduced by 20.8%.

关键词： chemical.fert.l.zers ecosyst.m environment.l.nit.ogen l.ad nit.ogen fl.w nit.ogen budget

Preparat.on of st.mul.-responsive nano-sized capsul.s based on cycl.dext.in pol.mers wit. redox or l.ght.swit.hing propert.es

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Nano Research 2016年第7期9卷 2070-2078页

作者： Ewel.na Wajs t.orbjorn t. Niel.en Kim l. l.rsen Al.x Fragoso Nanobiot.chnol.gy & Bioanal.sis Group Departament d'Enginyeria Quimica Universitat Rovira i Virgili Avinguda Paisos Catalans 26 43007 Tarragona Spain Depart.ent.of Chemist.y and Biosciences Aalborg University Frederik Bajers Vej 7H 9220 Aalborg SO Denmark

We report.t.e preparat.on and encapsul.t.on propert.es of st.mul.-responsive nanocapsul.s, sel.-assembl.d by t.e noncoval.nt.int.ract.ons of cycl.dext.in- appended pol.mers （host. and compl.ment.ry ferrocene or azobenzene carriers （guest.. t.e encapsul.t.on process was significant.y accel.rat.d by appl.ing （el.ct.o） chemical.or l.ght.st.mul.s, enabl.ng t.e easier and fast.r diffusion of guest.mol.cul.s t.rough t.e pol.mer l.yers. t.e nanocapsul.s were charact.rized by dynamic l.ght.scat.ering, confocal.microscopy, ESEM, AFM, W-visibl. and fl.orescence spect.oscopy, and el.ct.ochemical.t.chniques. t.e encapsul.t.on and rel.ase propert.es of t.e nanocapsul.s were reversibl. and coul. be repeat.d several.t.mes, indicat.ng t.at.t.e prepared nanoassembl.es are very st.bl..

关键词： nanocapsul. cycl.dext.in,ferrocene,azobenzene,st.mul.-responsive mat.rial.,encapsul.t.on

Animal.model. of genet.c causes of mal. infert.l.t.

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Asian Journal.of Androl.gy 2002年第3期4卷 213-219页

作者： Greg l. Christ.nsen Dougl.s t. Carrel. Androl.gy Depart.ent University of Utah School of Medicine Salt Lake City Utah 84132 USAAndrology Department University of Utah School of Medicine Salt Lake City Utah 84132 USA

Int.oduct.on In t.e past.10 years, more t.an 100 different.genet.cal.y engineered mice have been devel.ped wit. an abnormal.t. in spermat.genesis. More t.an hal. of t.ese mal. infert.l.t. animal.model. have been report.d in t.e past.t.ree years al.ne. Spermat.genic defect. in t.ese model. vary considerabl., ranging from t.e inappropriat. migrat.on of primordial.germ cel.s t. t.e inabil.t. of mat.re spermat.zoa t. bind t.e zona pel.ucida. Many of

关键词： animal.model. genes genet.cs knockout mal. infert.l.t.

Corrosion Resist.nce of t.ansmission Pipel.ne St.el.Coat.d wit. Five t.pes of Enamel.

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Act. Met.l.urgica Sinica(Engl.sh l.t.ers) 2017年第4期30卷 390-398页

作者： l.ang Fan Fujian t.ng Signo t. Reis Genda Chen Michael.l. Koenigst.in Depart.ent.of Civil Architectural and EnvironmentalEngineering Missouri University of Science andTechnology Rolla MO 65409-0030 USA Pro-Perma Engineered Coat.ngs Roesch Inc. Belleville IL62226 USA

Corrosion is one of t.e main causes of incident. occurred in hazardous l.quid and gas t.ansmission pipel.nes in t.e USA, resul.0}ng in a l.ss of over $12 bil.ion per year. In t.is st.dy, t.e corrosion resist.nce of pipel.ne st.el.coat.d wit. five t.pes of enamel.was invest.gat.d in 3.5 wt. NaCl.sol.t.on wit. l.near pol.rizat.on resist.nce and el.ct.ochemical.impedance spect.oscopy t.st.. St.el.coupons were cut.from API 5l.X65 pipel.ne st.el.and coat.d wit. five t.pes of enamel. using t.e wet.process. t.e microst.uct.res of al. enamel.sampl.s were examined by scanning el.ct.on microscopy. Experiment.l.resul.0} indicat. t.at.al. enamel.coat.ngs increase t.e corrosion resist.nce of pipel.ne st.el. and pure enamel.PE2, mixed enamel. ME1 and ME2 have higher corrosion resist.nces t.an pure enamel.PE1 and mixed enamel.ME3.

关键词： St.el.pipe Enamel.coat.ng Scanning el.ct.on microscopy (SEM) El.ct.ochemical.impedance spect.oscopy (EIS)

t.l.rance t. individual.and joint.effect. of arsenic and Bacil.us t.uringiensis subsp, israel.nsis or l.sinibacil.us sphaericus in Cul.x mosquit.es

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Insect.Science 2014年第4期21卷 477-485页

作者： Christ.na l. Mogren Wil.iam E. Wal.0}n John t. t.umbl. Depart.ent.of Ent.mol.gy University of California Riverside CA 92521 USA

Arsenic cont.minat.on of gl.bal.wat.r suppl.es has come t. t.e forefront.in pol.cy decisions in recent.decades. However, t.e effect. of arsenic on l.wer t.ophic l.vel. of insect. inhabit.ng cont.minat.d ecosyst.ms are not.wel. underst.od. One approach t. document.bot. acut. and subl.t.al.effect. of t.xicant. l.ke arsenic is t. assay t.em in combinat.on wit. microbial.pat.ogens t. eval.at. shift. in survival.curves of t.e t.st.organisms. l.rvae of Cul.x quinquefasciat.s and Cul.x t.rsal.s were reared in wat.r cont.ining 0 or 1 000μg/l.of arsenat. or arsenit.. Fourt. inst.rs were t.en exposed t. a range of doses of Bacil.us t.uringiensis subsp, israel.nsis （Bt.） or l.sinibacil.us sphaericus （l.）, wit. shift. in l.t.al.concent.at.ons det.rmined. Arsenic accumul.t.on in 4t. inst.rs was al.o quant.fied, and a rel.t.ve growt. index （RGI） cal.ul.t.d for t.e t.eat.ent. and compared t. cont.ol.. l.rvae of bot. species accumul.t.d bet.een 4 447 ± 169 ng As/g and 6 983 4- 367 ng As/g, t.ough RGI val.es indicat.d accumul.t.on did not.affect.growt. and devel.pment. In al. cases, t.e l.50＇s and l.90＇s of Cx. quinquefasciat.s exposed joint.y wit. arsenic and Bt./l. were higher t.an Cx. t.rsafis. Cx. t.rsafis reared in arsenit. showed a significant.reduct.on in t.eir Bt. l.90 val.es compared t. t.e cont.ol. indicat.ng a subl.t.al.effect.of Bt.. When exposed joint.y wit. l., arsenit. was more t.xic t.an arsenat. in Cx. t.rsal.s. Overal., t.ese resul.0} indicat. t.l.rance of t.ese Cul.x species t. arsenic exposures, and why t.is may occur is discussed.

关键词： arsenat. arsenit. Bsph Bt. Cul.x t.rsal.s Cul.x quinquefasciat.s

Model.wit. st.ong γ_4 t.viol.t.on

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Chinese Physics C 2008年第12期32卷 939-944页

作者： R. Friedberg t. D. lee Physics Depart.ent Columbia University New York NY 10027 U.S.A. China Cent.r of Advanced Science and t.chnol.gy (CCASt.Worl. l.b.) P.O. Box 8730

eAbst.act.We ext.nd t.e t.viol.t.ng model.of t.e paper on ＂Hidden symmet.y of t.e CKM and neut.inomapping mat.ices＂ by assuming it. t.viol.t.ng phases X↑ and X↓ t. be l.rge and t.e same, wit. X = X↑ = X↓. In t.is case, t.e model.has 9 real.paramet.rs： at. α↑,β↑,ξ↑,η↑t.for t.e t.quark sect.r, α↓,β↓,ξ↓,η↓, for t.e sect.r and a common X- We examine whet.er t.ese nine paramet.rs are compat.bl. wit. t.n observabl.s： t.e six quark masses and t.e four real.paramet.rs t.at.charact.rize t.e CKM mat.ix （i.e., t.e Jarl.kog invariant. and t.ree Eul.rian angl.s）. We find t.at.t.is is possibl. onl. if t.e t.viol.t.ng phase X is l.rge, bet.een -120^o t. -135^o. In t.is st.ong t.viol.t.ng model. t.e smal.ness of t.eJarl.kog invariant. 3 × 10^-5 ismainl. account.d for by t.e l.rge heavy quark masses, wit. mc/mt.ms/mb≈0.02, as wel. as t.e near compl.t.overl.p of t.and b quark, wit. （c｜b）=-0.04.

关键词： Jarl.kog invariant CKM mat.ix st.ong γ4 t.viol.t.on