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China Ocean Engineering 2024年第2期38卷 297-312页

作者： ZHANG Yi CHEN Yue yun lai liANG Xu Ocean College Zhejiang UniversityZhoushan 316000China Hainan Institute Zhejiang UniversitySanya 572000China

This paper aims to enhance the compression capacity of underwater cylindrical shells by adopting the corrugated sandwich structure of *** cuttlebone suffers uniaxial external compression,while underwater cylindrical shells are in a biaxial compressive stress *** suit the biaxial compressive stress state,a novel bidirectional corrugated sandwich structure is proposed to improve the bearing capacity of cylindrical *** static and buckling analysis for the sandwich shell and the unstiffened cylindrical shell with the same volume-weight ratio are studied by numerical *** is indicated that the proposed sandwich shell can effectively reduce the ratio between circumferential and axial stress from 2 to 1.25 and improve the critical buckling load by about 1.63 *** simulation shows that optimizing and adjusting the structural parameters could significantly improve the advantage of the sandwich ***,the hydrostatic pressure tests for shell models fabricated by 3D printing are carried *** to the experimental results,the overall failure position of the sandwich shell is at the center part of the sandwich *** has been found the average critical load of the proposed sandwich shell models exceeds two times that of the unstiffened shell ***,the proposed bio-inspired bidirectional corrugated sandwich structure can significantly enhance the pressure resistance capability of cylindrical shells.

关键词： bio-inspiration bidirectional corrugation sandwich shell external pressure buckling

Effect of crystal morphology of ultrahigh-nickel cathode materials on high temperature electrochemical stability of lithium ion batteries

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Journal of Energy Chemistry 2024年第1期88卷 327-335,I0008页

作者： Bi Luo Hui li Haoyu Qi yun liu Chuanbo Zheng Weitong Du Jiafeng Zhang lai Chen School of Metallurgy Engineering Jiangsu University of Science and TechnologyZhangjiagang 215600JiangsuChina National Engineering Laboratory for High-Efficiency Recovery of Refractory Nonferrous Metals School of Metallurgy and EnvironmentCentral South UniversityChangsha 410083HunanChina School of Materials Science and Engineering Beijing Key Laboratory of Environmental Science and EngineeringBeijing Institute of TechnologyBeijing 100081China

Higher nickel content endows Ni-rich cathode materials liNi_(x)Co_yMn_(1-x-y)O_(2)(x>0.6)with higher specific capacity and high energy density,which is regarded as the most promising cathode materials for li-ion ***,the deterioration of structural stability hinders its practical application,especially under harsh working conditions such as high-temperature *** these circumstances,it becomes particularly critical to clarify the impact of the crystal morphology on the structure and high-temperature performance as for the ultrahigh-nickel ***,we conducted a comprehensive comparison in terms of microstructure,high-temperature long-cycle phase evolution,and high-temperature electrochemical stability,revealing the differences and the working mechanisms among polycrystalline(PC),single-crystalline(SC)and Al doped SC ultrahigh-nickel *** results show that the PC sample suffers a severe irreversible phase transition along with the appearance of microcracks,resulting a serious decay of both average voltage and the energy *** the Al doped SC sample exhibits superior cycling stability with intact layered ***-situ XRD and intraparticle structural evolution characterization reveal that Al doping can significantly alleviate the irreversible phase transition,thus inhibiting microcracks generation and enabling enhanced ***,it exhibits excellent cycling performance in pouch-type full-cell with a high capacity retention of 91.8%after 500 cycles at 55℃.This work promotes the fundamental understanding on the correlation between the crystalline morphology and high-temperature electrochemical stability and provides a guide for optimization the Ni-rich cathode materials.

关键词： Single-crystalline Ultrahigh-nickel cathode High-temperature performance Phase evolution

Pretreatment and analysis techniques development of TKIs in biological samples for pharmacokinetic studies and therapeutic drug monitoring

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Journal of Pharmaceutical Analysis 2024年第4期14卷 439-459页

作者： Lan Chen Yuan Zhang Yi-Xin Zhang Wei-lai Wang De-Mei Sun Peng-yun li Xue-Song Feng Yue Tan School of Pharmacy China Medical UniversityShenyang110122China Institute of Pharmacology and Toxicology Institution National Engineering Research Center for Strategic DrugsBeijing100850China Department of Gastroenterology Shengjing Hospital of China Medical UniversityShenyang110022China

Tyrosine kinase inhibitors(TKIs)have emerged as the first-line small molecule drugs in many cancer therapies,exerting their effects by impeding aberrant cell growth and proliferation through the modulation of tyrosine kinase-mediated signaling ***,there exists a substantial inter-individual variability in the concentrations of certain TKIs and their metabolites,which may render patients with compromised immune function susceptible to diverse infections despite receiving theoretically efficacious anticancer treatments,alongside other potential side effects or adverse ***,an urgent need exists for an up-to-date review concerning the biological matrices relevant to bioanalysis and the sampling methods,clinical pharmacokinetics,and therapeutic drug monitoring of different *** paper provides a comprehensive overview of the advancements in pretreatment methods,such as protein precipitation(PPT),liquid-liquid extraction(LLE),solid-phase extraction(SPE),micro-SPE(μ-SPE),magnetic SPE(MSPE),and vortex-assisted dispersive SPE(VA-DSPE)achieved since *** also highlights the latest analysis techniques such as newly developed high performance liquid chromatography(HPLC)and high-resolution mass spectrometry(HRMS)methods,capillary electrophoresis(CE),gas chromatography(GC),supercritical fluid chromatography(SFC)procedures,surface plasmon resonance(SPR)assays as well as novel nanoprobes-based biosensing *** addition,a comparison is made between the advantages and disadvantages of different approaches while presenting critical challenges and prospects in pharmacokinetic studies and therapeutic drug monitoring.

关键词： TKIs Microextraction technique HRMS methods Pharmacokinetic studies Therapeutic drug monitoring

Comprehensive DNA barcode reference library and optimization of genetic divergence threshold facilitate the exploration of species diversity of green lacewings (Neuroptera: Chrysopidae)

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Insect Science 2024年第2期31卷 613-632页

作者： Yan lai Kaiyu li Xingyue liu Deparment of Entomology Cllege of Plant ProtectionChina Agricultural UniversityBejingChina College of Bioogical Sciencs China Agricultural UniversityBeijingChina

Chrysopidae are a family of Neuroptera of significant importance in biocontrol against agricultural pests because of their predatory ***,the taxonomy of Chrysopidae lacks a comprehensive revision,which impedes the exploration of species diversity as well as the selection and the conservation of green lacewings as biocontrol *** have established a DNA barcode reference library of the Chinese green lacewings based on an approximately complete sampling(95.63%)in 25 of the 34 provincial regions in China,comprising 1119 barcodes of 25 genera and 197 species(representing 85%genera and 43.62%species from China).Combining other 1049 high quality green lacewing DNA barcodes,we first inferred the optimal threshold of interspecific genetic divergence(1.87%)for successful species identification in multiple simulated scenarios based on present *** further inferred the threshold of genetic divergence(7.77%)among genera with biocontrol *** inference and performance of the threshold appears to be mainly associated with the completeness of sampling,the proportion of closely related species,and the analytical *** new combinations,Apertochrysa platypa(Yang&Yang,1991)***.,Apertochrysa shennongana(Yang&Wang,1990)***.,Apertochrysa pictifacialis(Yang,1988)***.,Apertochrysa helana(Yang,1993)***.,Plesiochrysa rosulata(Yang&Yang,2002)***.,and Signochrysa hainana(Yang&Yang,1991),are proposed according to integrative species *** library and optimal threshold will effectively facilitate the exploration of species diversity of green *** study also provides a methodological reference in molecular delimitation of other insects.

关键词： Chrysopidae DNA barcode genetic distance optimal threshold species delimitation

Laser Powder Bed Fusion of Beta-Type Titanium Alloys for Biomedical Application:A Review

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Acta Metallurgica Sinica(English Letters) 2024年第1期37卷 17-28页

作者： Xuan Luo Chao Yang Dongdong li lai-Chang Zhang State Key Laboratory of Materials Processing and Die&Mould Technology Huazhong University of Science and TechnologyWuhan430074China National Engineering Research Center of Near-Net-Shape Forming for Metallic Materials Guangdong Provincial Key Laboratory for Processing and Forming of Advanced Metallic MaterialsSouth China University of TechnologyGuangzhou510640China Centre for Advanced Materials and Manufacturing School of EngineeringEdith Cowan University270 Joondalup DriveJoondalupPerthWA6027Australia

Additive manufacturing ofβ-type titanium alloy is expected to replace Ti-6Al-4V alloy in the field of orthopedic implantation because of their low elastic modulus,excellent corrosion resistance,and *** briefly introducing the laser powder bed fusion(LPBF)process and physical phenomena,this paper reviews the recent progresses in LPBF-edβ-type Ti *** strategies to strengthening and tougheningβ-type Ti alloys are critically *** is followed by the processing routes employed to achieve to low modulus for orthopedic applications,especially a new methodology for tailoring crystallographic orientation called multi-track coupled directional *** effect of processing and compositions on performance metrics ofβ-type Ti alloys included corrosion behavior,and biocompatibility is *** the end,challenges in additive manufacturing ofβ-type Ti alloys in future are highlighted,with the aim to ensue clinical application of LPBF-edβ-type Ti alloys.

关键词： β-type Ti alloys Laser powder bed fusion Mechanical properties Elastic modulus Biocompatibility

Constructing lithium-Free Anode/Separator Interface via 3D Carbon Fabric Scaffold for Ultrasafe lithium Metal Batteries

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Research 2024年第3期2023卷 359-368页

作者： Dongdong li Shengchen Yang Zijian Zheng Wen-Yong lai State Key Laboratory of Organic Electronics and Information Displays(SKLOEID) Institute of Advanced Materials(IAM)School of Chemistry and Life SciencesNanjing University of Posts and Telecommunications9 Wenyuan RoadNanjing 210023China Department of Materials Chemistry Huzhou University1 Xueshi RoadHuzhou 313000China Laboratory for Advanced Interfacial Materials and Devices School of Fashion and TextilesDepartment of Applied Biology and Chemical TechnologyResearch Institute for Intelligent Wearable Systems(RI-IWEAR)Research Institute for Smart Energy(RISE)The Hong Kong Polytechnic UniversityHong Kong SAR 999077China

Metallic lithium represents a promising anode candidate to be utilized in future high-energy lithium ***,the undesirable dendrite growth and fragile solid-electrolyte interphase(SEI)pose critical challenge for pursuing further practical *** contrast to traditional approaches of using inert/lithiophilicity coating,here,we demonstrate a reverse strategy of introducing a highly conductive and lithophobic carbon fabric(CF)scaffold on lithium foil to guide a favorable nucleation site of lithium far away from the anode/separator *** CF scaffold with high conductivity can couple with inner electric field for achieving a uniform distribution of the lithium-ion flux,while the lithophobic feature offers the condition to guide the preferred deposition of lithium onto the underlying lithium foil,which greatly reduces the risk of dendrite-induced short ***,the SEI immersed in the CF scaffold is well supported by CF fibers and therefore exhibits extremely high stability during charge–discharge *** a result,the lithium/CF anodes show>2,000-h stable cycling at 0.5 mA cm−*** metal batteries equipped with our lithium/CF anode deliver a high capacity retention of~99.99%per cycle,i.e.,retain~97.3%capacity after 200 *** unique interface-regulation strategy is versatile for various conductive scaffolds(e.g.,ultrathin and ultralight conductive fabrics),exhibiting high superiority for highly safe lithium metal batteries.

关键词： lithium equipped versatile

Preheating-assisted solid-state friction stir repair of Al-Mg-Si alloy plate at different rotational speeds

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International Journal of Minerals,Metallurgy and Materials 2024年第4期31卷 725-736页

作者： Hui Wang Yidi li Ming Zhang Wei Gong Ruilin lai yunping li State Key Laboratory of Powder Metallurgy Central South UniversityChangsha 410083China Research Institute of light Alloy Central South UniversityChangsha 410083China

Additive friction stir deposition(AFSD)is a novel structural repair and manufacturing technology has become a research hotspot at home and abroad in the past five *** this work,the microstructural evolution and mechanical performance of the Al-Mg-Si alloy plate repaired by the preheating-assisted AFSD process were *** evaluate the tool rotation speed and substrate preheating for repair quality,the AFSD technique was used to additively repair 5 mm depth blind holes on 6061 aluminum alloy *** results showed that preheat-assisted AFSD repair significantly improved joint bonding and joint strength compared to the control non-preheat substrate ***,increasing rotation speed was also beneficial to improve the metallurgical bonding of the interface and avoid volume *** preheating conditions,the UTS and elongation were positively correlated with rotation *** the process parameters of preheated substrate and tool rotation speed of 1000 r/min,defect-free specimens could be obtained accompanied by tensile fracture occurring in the substrate rather than the repaired *** UTS and elongation reached the maximum values of 164.2MPa and 13.4%,which are equivalent to 99.4%and 140%of the heated substrate,respectively.

关键词： additive friction stir deposition structural repair tool rotation speed Al alloy

A booming field of large animal model research

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Zoological Research 2024年第2期45卷 311-313页

作者： Xiao-Jiang li liangxue lai Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)GHM Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong 510632China State Key Laboratory of Bioactive Molecules and Druggability Assessment Jinan UniversityGuangzhouGuangdong 510632China CAS Key Laboratory of Regenerative Biology Guangdong Provincial Key Laboratory of Stem Cell and Regenerative MedicineGuangzhou Institutes of Biomedicine and HealthChinese Academy of SciencesGuangzhouGuangdong 510530China

Animal models are integral to the study of fundamental biological processes and the etiology of human *** animal models,especially those involving mice,have yielded abundant and significant insights,greatly enhancing ... 详细信息

关键词： mechanisms insight field

Endoscopic treatment of extreme esophageal stenosis complicated with esophagotracheal fistula: A case report

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 239-247页

作者： Jia-Heng Fang Wei-Min li Cheng-Hai He Jian-liang Wu yun Guo Zhi-Chao lai Guo-Dong li Department of Gastroenterology Hangzhou Normal University Affiliated HospitalHangzhou 310000Zhejiang ProvinceChina

BACKGROUND At present,there is no unified and effective treatment for extreme corrosive esophageal stenosis(CES)with esophagotracheal fistula(ETF).This case had extreme and severe esophageal stenosis(ES)and ETF after ingesting an enzyme-based chemical detergent,resulting in a serious pulmonary infection and severe *** gastrointestinal imaging showed that he had an ETF,and endoscopy showed that he had extreme and severe esophageal *** case was complex and difficult to *** to the domestic and foreign lite-rature,there is no universal treatment that is *** SUMMARY A patient came to our hospital with extreme ES,an ETF,and severe malnutrition complicated with pulmonary tuberculosis 1 mo after the consumption of an enzy-me-based *** ES was serious,and the endoscope was unable to pass through the *** treated him by endoscopic incision method(EIM),esophageal stent placement(ESP),and endoscopic balloon dilation(EBD)by using the bronchoscope and *** treatment not only closed the ETF,but also expanded the esophagus,with minimal trauma,greatly reducing the pain of the *** to the literature,there are no similar reported *** We report,for the first time,a patient with extreme CES complicated with ETF,where the endoscope could not be passed through his esophagus but he could be examined by bronchoscopy and treated by EIM,ESP,and EBD.

关键词： Extreme corrosive esophageal stenosis Esophagotracheal fistula Endoscopic incision method Esophageal stent placement Endoscopic balloon dilation Case report

Finite barrier bound state

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light(Science & Applications) 2024年第4期13卷 664-671页

作者： Tao liu Kai Bai Yicheng Zhang Duanduan Wan yun lai C.T.Chan Meng Xiao Key Laboratory of Artificial Micro-and Nano-structures of Ministry of Education and School of Physics and Technology Wuhan University430072 WuhanChina. National Laboratory of Solid State Microstructures School of Physicsand Collaborative Innovation Center of Advanced MicrostructuresNanjing University210093 NanjingChina. Department of Physics The Hong Kong University of Science and TechnologyClear Water BayKowloon999077Hong KongChina. Wuhan Institute of Quantum Technology 430206 WuhanChina

A boundary mode localized on one side of a finite-size lattice can tunnel to the opposite side which results in unwanted *** wisdom tells that the tunneling probability decays exponentially with the size of the system which thus requires many lattice sites before eventually becoming negligibly *** we show that the tunneling probability for some boundary modes can apparently vanish at specific ***,similar to bound states in the continuum,a boundary mode can be completely trapped within very few lattice sites where the bulk bandgap is not even *** intriguingly,the number of trapped states equals the number of lattice sites along the normal direction of the *** provide two configurations and validate the existence of this peculiar finite barrier-bound state experimentally in a dielectric photonic crystal at microwave *** work offers extreme flexibility in tuning the coupling between localized states and channels as well as a new mechanism that facilitates unprecedented manipulation of light.

关键词： boundary state eventually