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国际医学放射学杂志 2010年第5期 488-489页

作者： l.s.politi R.Forghani C.Godi A.G.Resti M.Ponzoni s.Bianchi 陈柱 Department of Neuroradiology and Neuroradiology Re-search Unit San Raffaele Scientific Institute

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Retina stem cells,hopes and obstacles

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World Journal of stem Cells 2021年第10期13卷 1446-1479页

作者： Olga l German Harmonie Vallese-Maurizi Tamara B soto Nora P Rotstein luis Enrique politi Department of Biology Biochemistry and PharmacyUniversidad Nacional del SurBahia blanca 8000Buenos AiresArgentina Department of Biology Biochemistry and PharmacyUniversidad Nacional del Surand Neurobiology DepartmentInstituto de Investigaciones Bioquímicas de Bahía Blanca(INIBIBB)ConicetBahía Blanca 8000Buenos AiresArgentina

Retinal degeneration is a major contributor to visual dysfunction *** it comprises several eye diseases,loss of retinal pigment epithelial(RPE)and photoreceptor cells are the major contributors to their *** therapies included diverse treatments,such as provision of anti-vascular endothelial growth factor and many survival and trophic factors that,in some cases,slow down the progression of the degeneration,but do not effectively prevent *** finding of stem cells(sC)in the eye has led to the proposal of cell replacement strategies for retina *** using different types of sC,such as retinal progenitor cells(RPCs),embryonic sC,pluripotent sCs(PsCs),induced PsCs(iPsCs),and mesenchymal stromal cells,capable of self-renewal and of differentiating into multiple cell types,have gained ample *** preclinical studies have assessed transplantation of sC in animal models,with encouraging *** aim of this work is to revise the different preclinical and clinical approaches,analyzing the sC type used,their efficacy,safety,cell attachment and integration,absence of tumor formation and immunorejection,in order to establish which were the most relevant and *** addition,we examine the questions and concerns still open in the *** data demonstrate the existence of two main approaches,aimed at replacing either RPE cells or *** evidence suggests that RPCs and iPsC are the best candidates,presenting no ethical concerns and a low risk of *** trials have already supported the safety and efficacy of sC *** concerns are pending,such as the risk of tumor formation,lack of attachment or integration of transplanted cells into host retinas,immunorejection,cell death,and also ***,the amazing progress in the field in the last few years makes it possible to envisage safe and effective treatments to restore vision loss in a near future.

关键词： Retina regeneration stem cells Retina stem cell transplantation Cancer stem cells Photoreceptor replacement

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Competition between fusion-evaporation and multifragmentation in central collisions in ^(58)Ni+^(48)Ca at 25A MeV

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Nuclear science and Techniques 2013年第5期24卷 82-88页

作者： FRANCAlANZA l ABBONDANNO U AMORINI F BARlINI s BINI M BOUGAUlT R BRUNO M CARDEllA G CAsINI G AGOsTINO M D' De FIlIPPO V De sANCTIs J GERACI E GIUssANI A GRAMEGNA F GUIOT B KRAVCHUK V la GUIDARA E lANZAlONE G le NEINDRE N MAIOlINO C MARINI P MOREllI l OlMI A PAGANO A PAPA M PIANTEllI s PIRRONE s politi G POGGI G PORTO F RUssOTTO P RIZZO F VANNINI G VANNUCCI l INFN laboratori Nazionali del sud-lNs Catania 95123Italy Dipartimento di Fisica Universitàdi Catania I-95129Italy INFN sezione di Trieste Trieste I-34127Italy Dipartimento di Fisica Universitàdi FirenzeINFN Sezione di Firenze 1-50139Italy lPC Caen IN2P3-CNRS/ENSICAEN and UniversitéF-14050 Caen cedex 5-140France Dipartimento di Fisica Universitàdi Bologna and INFN Sezione di Bologna 4-50121Italy INFN sezione di Catania I-95129 Italy INFN sezione di Firenze I-50139 Italy Dipartimento di Fisica Universitàdi Milano and INFN Sezione di Milano1-20126Italy INFN laboratori Nazionali di legnaro 1-35020 Italy Centro siciliano di Fisica Nucleare e struttura della Materia Catania 1-95129Italy UniversitàKore Enna 1-94100Italy

The experimental data concerning the58Ni+48Ca reaction at Elab(Ni)=25A MeV,collected by using the CHIMERA 4π device,have been analyzed in order to investigate the competition among different reaction mechanisms for central collisions in the Fermi energy *** a main criterion for centrality selection we have chosen the flow angle(flow) method,making an event-by-event analysis that considers the shape of events,as it is determined by the eigenvectors of the experimental kinetic-energy *** the selected central events(flow >60°) some global variables,good to characterize the pattern of central collisions have been *** main features of the reaction products were explored by using different constraints on some of the relevant observables,like mass and velocity distributions and their *** emphasis was devoted,for central collisions,to the competition between fusion-evaporation processes with subsequent identification of a heavy residue and a possible multifragmentation mechanism of a well defined(if any) transient nuclear *** evolution of the system and pre-equilibrium emission were taken into account by simulating the reactions in the framework of transport *** approaches have been envisaged(dynamical stochastic BNV calculations + sequential sIMON code,QMD,CoMD,etc.).Preliminary comparison of the experimental data with BNV calculations shows reasonable agreement with the assumption of sequential multifragmentation emission in the mass region of IMFs close to the heavy *** deviations from sequential processes were found for those IMFs in the region of masses intermediate between the mass of heavy residues and the mass of light *** simulations are in *** experimental analysis will be enriched also by information obtained inspecting the IMF-IMF correlation function,in order to elucidated the nature of space-time decay property of the emitting source associated with events having

关键词：多重碎裂中心碰撞蒸发过程 MeV 竞争熔合国际货币基金组织事件分析

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宫颈癌患者脊髓髓内和软脑膜转移1例

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世界核心医学期刊文摘（妇产科学分册） 2006年第10期2卷 48-48页

作者： Kastritis E. Moulopoulos l.A. politi Ek. A. Bamias 朱磊 Department of Clinical Therapeutics Alexandra Hospital Athens University School of Medicine 31 Komninon St Haidari 124 62 Athens Greece

Background.: Neoplastic meningitis in patients with carcinoma of the uterine cervix is unusual in the course of their diseases. Even more unusual are intramedullary spinal metastases. Case.: We report the case of a 64-year-old woman who presented with leptomeningeal and intramedullary spinal cord metastases from a grade 2 squamous cell cancer of the uterine cervix. This is just the second case of intramedullary metastases from cervical carcinoma. Conclusion.: Neoplastic meningitis or intramedullary metastases are extremely rare in the course of uterine cervix carcinoma. Nevertheless, when indicated by symptoms, patients should undergo MRI of the brain and/or spine and have a lumbar puncture performed, for the diagnosis of this devastating complication. Treatment is mainly palliative but may offer symptom relief.

关键词：软脑膜脑脊膜转移姑息性腰椎穿刺

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智愚说对先秦儒家人道观的消解及其文化影响

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山东大学学报（哲学社会科学版） 2002年第2期 99-102,108页

作者：张骏翚山东大学古籍所山东济南250100

先秦儒家由“天”出发，提出了诸如“天民 ”这样的极富人文色彩和人道意义的范畴及命题，并因此建立起了其独具特色的人道价值观，但是，由于他们在智愚问题上的过分关注和强调，而使得其人道价值观在现实政治层面，几无实践性意义... 详细信息

先秦儒家由“天”出发，提出了诸如“天民 ”这样的极富人文色彩和人道意义的范畴及命题，并因此建立起了其独具特色的人道价值观，但是，由于他们在智愚问题上的过分关注和强调，而使得其人道价值观在现实政治层面，几无实践性意义可言。也就是说，先秦儒家同时强调的智愚说，在很大程度上消解、甚至否定了其原有的人道价值论，进而对中国传统文化发生了重大影响。

关键词：天人道人性智愚民

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