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Very-high-frequency probes for atomic force microscopy with silicon optomechanics

Microsystems & Nanoengineering 2022年第2期8卷 35-48页

作者： l.schwab P.E.Allain N.Mauran X.Dollat l.Mazenq D.lagrange M.Gély S.Hentz G.Jourdan I.Favero B.legrand laboratoire d'Analyse et d'Architecture des Systemes Universite de ToulouseCNRS UPR 800131031 ToulouseFrance laboratoire Materiaux et Phenomenes Quantiques Universite de ParisCNRS UMR 716275013 ParisFrance Universite Grenoble Alpes CEALETIMinatec Campus38000 GrenobleFrance

Atomic force microscopy(AFM)has been consistently supporting nanosciences and nanotechnologies for over 30 years and is used in many fields from condensed matter physics to *** enables the measurement of very weak forces at the nanoscale,thus elucidating the interactions at play in fundamental ***,we leverage the combined benefits of micro/nanoelectromechanical systems and cavity optomechanics to fabricate a sensor for dynamic mode AFM at a frequency above 100 *** frequency is two decades above the fastest commercial AFM probes,suggesting an opportunity for measuring forces at timescales unexplored thus *** fabrication is achieved using very-large-scale integration technologies derived from photonic silicon *** probe's optomechanical ring cavity is coupled to a 1.55 pm laser light and features a 130 MHz mechanical resonance mode with a quality factor of 900 in air.A limit of detection in the displacement of 3×10^(-16)m/VHz is obtained,enabling the detection of the Brownian motion of the probe and paving the way for force sensing experiments in the dynamic mode with a working vibration amplitude in the picometer *** inserted in a custom AFM instrument embodiment,this optomechanical sensor demonstrates the capacity to perform force-distance measurements and to maintain a constant interaction strength between the tip and sample,an essential requirement for AFM *** indeed show a stable closed-loop operation with a setpoint of 4 nN/nm for an unprecedented subpicometer vibration amplitude,where the tip-sample interaction is mediated by a stretched water meniscus.

关键词： cavity maintain instrument

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西部大陆边缘(法国—意大利阿尔卑斯山脉)的演化:砂岩矿物成分作为板块构造环境的一种标志

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世界地质 1983年第2期 97-111页

作者： l.schwab 刘立泽

有关西部阿尔卑斯或法国——意大利阿尔卑斯山的大多数板块构造发展模式,反映了特提斯海(局部 Piedmont)的“西部”或“法国”大陆边缘从晚古生代到第三纪时期存在着几个构造性质不同的类型。从晚古生代到侏罗纪,这个边缘最初是一个裂... 详细信息

有关西部阿尔卑斯或法国——意大利阿尔卑斯山的大多数板块构造发展模式,反映了特提斯海(局部 Piedmont)的“西部”或“法国”大陆边缘从晚古生代到第三纪时期存在着几个构造性质不同的类型。从晚古生代到侏罗纪,这个边缘最初是一个裂谷的、被动边缘,以后逐渐下陷为大西洋型边缘。在白垩纪和第三纪时期,火山活动、蓝片岩变质作用和迅速抬升与侵蚀的迹象都反映了 Piedmont(和 Valais?)洋盆呈现强烈消亡,结果形成了类似喜玛拉雅接合缝的造山高地及局部的岛弧——海沟——陆缘海系统,甚至可能有转换断层。形成了造山型大陆活动边缘的一切特征.类似于现代地中海和环太平洋的边缘.对于现代洋盆和大陆边缘的砂进行的综合分析、已经揭示了,古代砂岩的格架矿物组成能被用来鉴别以前的大陆边缘和洋盆在时间、空间上的板块构造环境。从法国 Valence 到意大利的都林,穿过西阿尔卑斯山采集的古代砂岩样品的详细的岩类学研究,普遍地证实了这个观点。不过,本文着重论述砂岩矿物与板块构造环境之间的较明确的必然关系.

关键词：砂岩矿物组成碎屑岩大地构造板块构造阿尔卑斯山矿物成份矿物成分

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Small extrachromosomal circular DNA in amyotrophic lateral sclerosis matter

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Neural Regeneration Research 2025年第5期20卷 1411-1413页

作者： Marcos J.Arauzo-Bravo Daniela Gerovska Matthias schwab Alexandra Kretz Computational Biology and Systems Biomedicine Biodonostia Health Research InstituteSan SebastianSpain Basque Foundation for Science IKERBASQUEBilbaoSpainMax Planck Institute for Molecular BiomedicineComputational Biology and Bioinformatics GroupMünsterNorth Rhine-WestphaliaGermany Department of Cell Biology and Histology Faculty of Medicine and NursingUniversity of Basque Country(UPV/EHU)LeioaSpain Department of Neurology Jena University HospitalJenaThuringiaGermany

Comprehensive studies identify motor neuron spectrum disorders including amyotrophic lateral sclerosis(AlS)as globally rising fatal disorders with the highest prevalence in aging populations,influenced by ethnicity and ancestry(GBD 2016 Motor Neuron Disease Colla borators,2018).While~10% of diagnoses involve a family history(fAlS),most cases are considered sporadic(sAlS).However,population-based studies suggest that even cases without a common index mutation impart heritability(Ryan et al.,2019),indicating a crucial role of rare and as yet unknown genetic denominators.

关键词： amyotrophic sclerosis

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Beginning from the end:the presynaptic terminal as a pathomechanism hub in frontotemporal dementia and amyotrophic lateral sclerosis

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Neural Regeneration Research 2025年第11期20卷 3217-3218页

作者： laura Huggon Emma l.Clayton UK Dementia Research Institute at King’s College london LondonUK Department of Basic and Clinical Neuroscience Institute of Psychiatry Psychology&NeuroscienceKing’s College LondonLondonUK

Frontotemporal dementia and amyotrophic lateral sclerosis:Frontotemporal dementia(F T D)and amyo t rophic lateral sclerosis(AlS)are neurodegenerative diseases with significant overlapping *** these neurodegenerative diseases affect different neuronal populations(with FTD affecting neurons of the frontal and temporal lobes,and AlS affecting upper and lower motor neurons),these two diseases are complexly *** and AlS exist on a disease spectrum,with shared genetic causes,clinical presentations,and pathologies.

关键词： diseases amyotrophic sclerosis

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Multiple sclerosis is at a checkpoint: advancing the program

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon C.Smith Jessica l.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(CNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

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Generation of brain vascular heterogeneity:recent advances from the perspective of angiogenesis

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Neural Regeneration Research 2025年第7期20卷 2013-2014页

作者： Nathanael J.lee Ryota l.Matsuoka Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Molecular Medicine Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA

Heterogeneous proper t i es of vascular endothelial cells in the brain:The brain displays large energy dynamics and consumption,and this high level of metabolic demands is fulfilled by a continuous supply of glucose and oxygen through its vascular *** vasculature consists of highly divergent blood vessel branches,giving rise to a dense network of capillaries that supply blood to all cells across the *** elaborated vascular network is thought to develop via angiogenesis,a process in which new blood vessels grow from pre-existing *** capillaries exhibit organotypic features distinct from other tissues and are formed primarily by two major endothelial cell(EC)types:those that form the semi-permeable blood-brain barrier(BBB)and those that develop highly permeable pores known as fenestrae(Matsuoka et al.,2022).The structural and functional differences between BBB and fenestrated vascular ECs represent a fundamental feature of brain vasculature and form the foundation for both brain function and homeostasis.

关键词： angiogenesis homeostasis network

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Force and impulse multi-sensor based on flexible gate dielectric field effect transistor

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 214-220页

作者： Chao Tan Junling lü Chunchi Zhang Dong liang lei Yang Zegao Wang College of Materials Science and Engineering Sichuan UniversityChengdu 610065China The 54th Research Institute of China Electronics Technology Group Corporation Shijiazhuang 050081China

Nowadays,force sensors play an important role in industrial production,electronic information,medical health,and many other ***-dimensional material-based filed effect transistor(2D-FET)sensors are competitive with nano-level size,lower power consumption,and accurate ***,few of them has the capability of impulse detection which is a path function,expressing the cumulative effect of the force on the particle over a period of *** we fabricated the flexible polymethyl methacrylate(PMMA)gate dielectric MoS_(2)-FET for force and impulse sensor *** systematically investigated the responses of the sensor to constant force and varying forces,and achieved the conversion factors of the drain current signals(I_(ds))to the detected impulse(I).The applied force was detected and recorded by I_(ds)with a low power consumption of~30 *** sensitivity of the device can reach~8000%and the 4×1 sensor array is able to detect and locate the normal force applied on ***,there was almost no performance loss for the device as left in the air for two months.

关键词： flexible gate dielectric transistor force sensor impulse sensor force sensor array

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Viscosity and structure relationship with equimolar substitution of CaO with MgO in the CaO–MgO–Al_(2)O_(3)–SiO_(2)slag melts

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 70-79页

作者： Yong Hou Shuo Zhang Jie Dang Jia Guo Hanghang Zhou Xuewei lü College of Materials Science and Engineering Chongqing UniversityChongqing 400044China Chongqing Key laboratory of Vanadium-Titanium Metallurgy and New Materials Chongqing UniversityChongqing 400044China

Currently,the Al_(2)O_(3)content in the high-alumina slag systems within blast furnaces is generally limited to 16wt%–18.5wt%,making it challenging to overcome this *** most studies that concentrated on managing the MgO/Al_(2)O_(3)ratio or basicity,this paper explored the effect of equimolar substitution of MgO for CaO on the viscosity and structure of a high-alumina CaO-MgO-Al_(2)O_(3)-SiO_(2)slag system,providing theoretical guidance and data to facilitate the application of high-alumina *** results revealed that the viscosity first decreased and then increased with higher MgO substitution,reaching a minimum at 15mol%MgO *** transform infrared spectroscopy(FTIR)results found that the depths of the troughs representing[SiO_(4)]tetrahedra,[AlO_(4)]tetrahedra,and Si-O-Al bending became progressively deeper with increased MgO *** of the Raman spectra showed that the average number of bridging oxygens per Si atom and the X_(Q^(3))/X_(Q^(2))(X_(Q^(i))is the molar fraction of Q^(i) unit,and i is the number of bridging oxygens in a[SiO_(4)]tetrahedral unit)ratio increased from 2.30 and 1.02 to 2.52 and 2.14,respectively,indicating a progressive polymerization of the silicate structure.X-ray photoelectron spectroscopy(XPS)results highlighted that non-bridging oxygen content decreased from 77.97mol% to 63.41mol% with increasing MgO concentration,whereas bridging oxygen and free oxygen contents *** analysis demonstrated a gradual increase in the polymerization degree of the tetrahedral structure with the increase in MgO ***,bond strength is another important factor affecting the slag *** occurrence of a viscosity minimum can be attributed to the complex evolution of bond strengths of non-bridging oxygens generated during depolymerization of the[SiO_(4)]and[AlO_(4)]tetrahedral structures by CaO and MgO.

关键词： aluminosilicate viscosity structure spectroscopy

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Gauge Inverse Monoids

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Algebra Colloquium 2020年第2期27卷 181-192页

作者： Emil Daniel.schwab Department of Mathematical Sciences The University of Texas at El Paso El PasoTexas 79968USA

The paper introduces a class of inverse(sub)monoids which contains Jones-lawson’s gauge inverse(sub)*** aim is to give examples and the basic properties of these ***-lawson’s gauge inverse monoid,as an inverse submonoid of the polycyclic monoid,is the prototype in our development *** generalization leads also to Mea-kin-Sapir type results involving bijections between special congruences and special wide inverse submonoids.

关键词： inverse semigroup gauge inverse monoid polycyclic monoid

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Non-existence of Shimura curves of Mumford type generically in the non-hyperelliptic locus

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Science China Mathematics 2025年

作者： Xin lü Shengli Tan Kang Zuo School of Mathematical Sciences Key Laboratory of Mathematics and Engineering Applications(Ministry of Education) Shanghai Key Laboratory of Pure Mathematics and Mathematical PracticeEast China Normal University School of Mathematics and Statistics Wuhan University Institut für Mathematik Universit?t Mainz

We show that there does not exist any Shimura curve with a strictly maximal Higgs field generically in the Torelli locus of non-hyperelliptic curves of genus g≥4. In particular, Shimura curves of Mumford type are not...

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