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World Journal of Psychiatry 2018年第1期8卷 1-11页

作者： Paul Henry lysaker Jay A hamm Ilanit Hasson-Ohayon Michelle l Pattison Bethany l leonhardt Department of Psychiatry Roudebush VA Med Ctr and the Indiana University School of Medicine Department of Psychiatry Indiana University School of Medicine Department of Psychiatry Eskenazi Health Midtown Community Mental Health Eskenazi Health Midtown Community Mental Health Department of Psychology Hasson-Ohayon I Bar Ilan Univ Dept Psychol Department of Psychology University of Indianapolis College of Applied Behavioral Sciences

Research indicates that individuals with schizophrenia recover. Recovery, however means different things to different individuals and regardless of what kind of experiences define recovery, the individual diagnosed with the serious mental illness must feel ownership of their recovery. This raises the issue of how mental health services should systematically promote recovery. This paper explores the practical implications for research on metacognition in schizophrenia for this issue. First, we present the integrated model of metacognition, which defines metacognition as the spectrum of activities which allow individual to have available to themselves an integrated sense of self and others as they appraise and respond to the unique challenges they face. Second, we present research suggesting that many with schizophrenia experience deficits in metacognition and that those deficits compromise individuals' abilities to manage their lives and mental health challenges. Third, we discuss a form of psychotherapy inspired by this research, Metacognitive Reflection and Insight Therapy which assists individuals to recapture the ability to form integrated ideas about themselves and others and so direct their own recovery. The need for recovery oriented interventions to focus on process and on patient's purposes, assess metacognition and consider the intersubjective contexts in which this occurres is discussed.

关键词： Schizophrenia Rehabilitation Self Psychosis Metacognition Recovery Psychotherapy Social cognition

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议程设置理论与后大众媒体时代的民意研究

国际新闻界 2004年第4期 5-9页

作者： Donald l. Shaw,Donald l. Shaw,Bradley J. hamm 美国北卡罗莱纳大学美国北卡罗莱纳大学美国伊降大学

关于媒体与民意的理论大部分提出于 1 93 0到 1 980年之间 ,这是一个仅仅拥有传统信息选择方式的时代。麦库姆斯和肖 (1 972 )最初提出议程设置理论时 ,用北卡罗莱纳州的教堂山 (ChapelHill)社区作为研究对象 ,而现在那里的媒介使用情... 详细信息

关于媒体与民意的理论大部分提出于 1 93 0到 1 980年之间 ,这是一个仅仅拥有传统信息选择方式的时代。麦库姆斯和肖 (1 972 )最初提出议程设置理论时 ,用北卡罗莱纳州的教堂山 (ChapelHill)社区作为研究对象 ,而现在那里的媒介使用情况也已经发生了巨变。当我们迎来议程设置理论提出 3 0周年的时候 ,教堂山的受众现在面临的信息选择令人惊叹。在 2 0世纪 90年代 ,肖提出 ,美国的大众媒介已经经历了“兴和衰”(riseandfall)。肖认为 ,大众媒体时代结束于 2 0世纪 80年代。议程设置研究是否能像之前的 3 0年那样 ,继续开展下去 ?当受众使用着上百个信息来源时 ,议程设置和民意研究会产生何种变化 ?这是本文将要回答的问题

关键词：议程设置理论后大众媒体时代民意研究

Assessing the Malignancy of Hepataocellular Carcinoma in Cirrhosis Using the Hepatocellular Contrast Agent Gd-EOB-DTPA and Correlation with the Cytometric DNA Index

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Advances in Molecular Imaging 2013年第1期3卷 1-7页

作者： R.Rottgen S.Kobi C.Grieser F.Streitparth H.Al-Abadi A.Duerr W.Faber J.Pratschke P.Neuhaus B.hamm l.ludemann Klinik fur Radiologie Charite’Campus Virchow Augustenburger Platz 1BerlinGermany Klinik fur Allgemein-Visceral-und Transplantationschirurgie Charite’Campus Virchow Augustenburger Platz 1BerlinGermany Klinik fur Visceral- Transplantations-und ThoraxchirurgieUniversitatsklinikum InnsbruckInnsbruckAustria Abteilung fur Strahlenphysik Universitatsklinikum EssenEssenGermany

Aim: Investigation whether the signal intensity of hepatocellular carcinoma (HCC) on dynamic magnetic resonance imaging (MRI) with hepatocellular contrast medium (CM) correlates with the histologic malignancy grade and cytometric DNA index. Material and Methods: MRI at 1.5 T with hepatocellular CM Gd-DTPA-EOB of 63 patients (52 men, 11 women;64.0 ± 8.5 years) with HCC in cirrhosis. SI of the tumor and liver tissue in sequences (T1, T1fs, T2fs, T1fs + CM (arterial, venous, late venous phase) were correlated like the asymmetry coefficient of the SI in the arterial and venous phases respective the native and late venous phases of the tumor with the histologic malignancy grade and DNA index indicating the grade of abnormal DNA steam line respective aneuploid DNA. Results: SI did not significantly correlate with the histologic malignancy grade or DNA index for precontrast or postcontrast images. There is a significant correlation for the asymmetry coefficient of the SI in the arterial and venous phases with the DNA-index (p values of 0.00089 (Pearson) and 0.0082 (Spearman). Conclusion: A highly arterialized hepatocellular carcinoma with rapid washout in the venous phase corresponds to a higher malignant potential. These findings suggest that the MR parameters investigated here may predict the malignant potential and prognosis of HCC before surgery.

关键词： Hepatocellular Carcinoma DNA Index DNA Cytometry Malignancy Grading

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尿血管紧张素原与血压的钠敏感性和钾敏感性

中华高血压杂志 2015年第6期23卷 525-525页

作者：刘莉叶鹏 Rebholz CM Chen J Zhao Q Chen JC li J Cao J Gabriel Navar l.lee hamm l Gu D He J

尿中排泄的血管紧张素原（尿血管紧张素,urine angiotensinogen,UAGT）可作为评估肾内肾素血管紧张素系统活性的生物学标记物。研究人员对盐敏感性研究遗传流行病学网络资料库中受试者的UAGT与血压钠敏感性和钾敏感性之间的关系进行探... 详细信息

尿中排泄的血管紧张素原（尿血管紧张素,urine angiotensinogen,UAGT）可作为评估肾内肾素血管紧张素系统活性的生物学标记物。研究人员对盐敏感性研究遗传流行病学网络资料库中受试者的UAGT与血压钠敏感性和钾敏感性之间的关系进行探讨。方法：随机抽取100名受试者参加,并对其进行如下干预：7d低钠膳食（摄入钠51.3mmol/d）,7d高钠膳食（307.8mmol/d）。

关键词：血压钠敏感性血管紧张素原肾素血管紧张素系统尿生物学标记物流行病学网络钾 urine

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X-ray focusing with efficient high-NA multilayer laue lenses

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light(Science & Applications) 2017年第1期6卷 95-103页

作者： Saša Bajt Mauro Prasciolu Holger Fleckenstein Martin Domaracký Henry N Chapman Andrew J Morgan Oleksandr Yefanov Marc Messerschmidt Yang Du Kevin T Murray Valerio Mariani Manuela Kuhn Steven Aplin Kanupriya Pande Pablo Villanueva-Perez Karolina Stachnik Joe PJ Chen Andrzej Andrejczuk Alke Meents Anja Burkhardt David Pennicard Xiaojing Huang Hanfei Yan Evgeny Nazaretski Yong S Chu Christian E hamm Photon Science DESYNotkestrasse 85Hamburg 22607Germany Center for Free-Electron laser Science DESYNotkestrasse 85Hamburg 22607Germany Department of Physics University of HamburgLuruper Chaussee 149Hamburg 22607Germany Centre for Ultrafast Imaging Luruper Chaussee 149Hamburg 22607Germany National Science Foundation BioXFEl Science and Technology Center 700 Ellicott StreetBuffaloNY 14203USA Department of Physics Arizona State UniversityTempeAZ 85287USA Faculty of Physics University of BialystokCiolkowskiego 1L Str.Bialystok 15-245Poland National Synchrotron light Source II Brookhaven National LaboratoryUptonNY 11973USA Alfred-Wegener Institute Helmholtz Center for Polar and Marine ResearchBussestr.27Bremerhaven 27570Germany

Multilayer laue lenses are volume diffraction elements for the efficient focusing of *** a new manufacturing technique that we introduced,it is possible to fabricate lenses of sufficiently high numerical aperture(NA)to achieve focal spot sizes below 10 *** alternating layers of the materials that form the lens must span a broad range of thicknesses on the nanometer scale to achieve the necessary range of X-ray deflection angles required to achieve a high *** poses a challenge to both the accuracy of the deposition process and the control of the materials properties,which often vary with layer *** introduced a new pair of materials—tungsten carbide and silicon carbide—to prepare layered structures with smooth and sharp interfaces and with no material phase transitions that hampered the manufacture of previous *** a pair of multilayer laue lenses(Mlls)fabricated from this system,we achieved a two-dimensional focus of 8.4×6.8 nm2 at a photon energy of 16.3 keV with high diffraction efficiency and demonstrated scanning-based imaging of samples with a resolution well below 10 *** high NA also allowed projection holographic imaging with strong phase contrast over a large range of *** error analysis indicates the possibility of achieving 1 nm focusing.

关键词： multilayer laue lenses multilayers ptychography X-ray holography X-ray optics

巴西诺卡菌致腿部溃疡及结节性淋巴管炎(法国)

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世界核心医学期刊文摘（皮肤病学分册） 2005年第12期1卷 34-35页

作者： hamm M. Friedel J. Siré C. Semon J. 罗素菊 Unité de Dermatologie Centre HospitalierWilliamMorey 7 quai de l' Hpital 71321 Chalon- sur- Sane Cedex France

Introduction. Nocardia brasiliensis is a very rarely reported cause of chronic phagedenic ulcerations. We report the case of an elderly woman who developed such an infection after falling on her right leg on the road in the Bresse country (an essentially agricultural and bovine- cattle breading region) and developed a chronic phagedenic ulcer secondarily complicated by nodular lymphangitis of the thigh. Case report. A 75 year- old woman fell on her right leg on the side of themain road outside her hamlet in the Bresse country and secondarily developed a chronique phagedenic ulceration. We first considered her as suffering from pyoderma gangrenosum. A complete scanning only revealed an autoimmune thyroiditis and a rapidly healing gastric ulceration, and none of the treatments, either local or systemic, helped the skin condition to heal. After 3 weeks of application of a local corticoid ointment, the patient developed fever, general malaise, an exacerbation of her wound and an infiltration of the skin round her knee, together with nodular lymphangitic dissemination. A supplementary bacterial swab disclosed massive proliferation of a slow- growing Gram- positive bacillus, which proved to be Nocardia brasiliensis, together with a methicillino- sensitive Staphylococcus aureus. The treatment with sulfamethoxazole- trimetoprim gave a rash after 12 hours and was changed to amoxicillin and clavulanic acid, which rapidly proved to be permanently effective. Discussion. The revelation of this particular slow- growing bacteria is difficult and requires bacterial swabs. Nocardia brasiliensis is relatively rare in primary skin ulcerations andwe discuss the reasons why an elderly women should find this bacteria on the road outside her hamlet in the French countryside. This particular infectious condition requires general scanning, to make sure that the primary skin condition does not extend to other organs. We review the therapeutical options for patients who exhibit allergic react

关键词：淋巴管炎巴西诺卡菌结节性坏疽性脓皮病皮质激素软膏病原菌感染全身检查革兰阳性杆菌炎性浸润股部

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对此双能量CT与动态增强CT及传统的单能量增强CT对瑞格非尼(Regorafenib)在临床前期肿瘤模型早期疗效的评估

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国际医学放射学杂志 2014年第5期 505-506页

作者： G.Knobloch G.Jost A.Huppertz B.hamm H.Pietsch 陈慧娟 Department of Radiology Charité–Universit tsmedizin BerlinCharité Campus VirchowAugustenburger Platz 113353 BerlinGermany

摘要目的对比双能量CT与动态对比增强CT和常规对比增强CT在评估临床前期瑞格非尼(regorafenib)早期治疗效果的潜在诊断价值。方法采用GS9l胶质瘤小鼠模型,

关键词：动态对比增强 Regorafenib 临床前期双能量格非 CT

Pathogenesis of fatty liver diseases and hepatocellular carcinoma

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liver Research 2022年第4期6卷 201-202页

作者： John Y.l.Chiang Tiangang li Integrative Medical Sciences Northeast Ohio Medical UniversityRootstownOHUSA Harold hamm Diabetes Center Department of PhysiologyUniversity of Oklahoma Health Sciences CenterOklahoma CityOKUSA

The prevalence of fatty liver diseases has increased rapidly in recent years to about 25%*** liver diseases are multi-faceted in pathogenesis,disease phenotype,and *** is important to understand disease pathogenesis and mechanism in order to develop effective and safe drug therapy for treating fatty liver *** fatty liver disease(AFlD,or alcohol associ-ated liver disease)and viral hepatitis have been the major causes of liver transplant,liver cancer,and death.

关键词： diseases mechanism. liver

在接受治疗的急性冠状动脉综合征患者中,肌钙蛋白峰值与长期缺血事件之间的关系

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中华高血压杂志 2017年第5期25卷 427-427页

作者：刘莉叶鹏 Goldstein SA Newby lK Cyr DD Neely M lüscher TF Brown EB White HD Ohman EM Roe MT hamm CW

非ST段抬高急性冠状动脉综合征（acutecoro-narysyndromes，ACS）患者肌钙蛋白水平与结局的关系虽然已经明确，但接受抗血小板治疗管理的非ST段抬高ACS患者肌钙蛋白水平与长期结局的关系尚未明确。

关键词：非ST段抬高急性冠状动脉综合征肌钙蛋白治疗管理患者缺血事件非ST段抬高ACS 峰值蛋白水平

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