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Intel—8089—一种集成I/O处理机

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微处理机 1980年第2期 69-86页

作者： K·A·El.ayat 何玉表 Intel公司

编者按——象大多数主机厂家所证实的那样,解决I/O控制问题的合理方法是采用智能I/O子系统。Intel的8089使微型计算机系统实现了这种能力。

关键词：变址寄存器 I/O Intel 存贮器存储器处理机总线接口地址空间主总线

Congenital anomalies of coronary artery misdiagnosed as coronary dilatations in Kawasaki disease:A clinical predicament

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World Journal of Clinical Pediatrics 2025年第1期14卷 93-100页

作者： Rakesh Kumar Pilania Pallavi l Nadig Suprit Basu Reva Tyagi Abarna Thangaraj Ridhima Aggarwal Munish Arora Arun Sharma Surjit Singh Manphool Singhal Pediatric Allergy Immunology Unit Department of PediatricsAdvanced Pediatrics CenterPost Graduate Institute of Medical Education and ResearchChandigarh 160012ChandīgarhIndia Department of Radiodiagnosis and Imaging Postgraduate Institute of Medical Education and ResearchChandigarh 160012ChandīgarhIndia

BACKGROUND 2D-echocardiography(2DE)has been the primary imaging modality in children with Kawasaki disease(KD)to assess coronary *** To report the presence and implications of incidental congenital coronary artery anomalies that had been misinterpreted as coronary artery abnormalities(CAAs)on *** Records of children diagnosed with KD,who underwent computed tomography coronary angiography(CTCA)at our center between 2013-2023 were *** identified 3 children with congenital coronary artery anomalies in this cohort on *** of CTCA and 2DE were compared in these 3 *** Of the 241 patients with KD who underwent CTCA,3(1.24%)had congenital coronary artery anomalies on CTCA detected *** all 3 patients,baseline 2DE had identified *** was then performed for detailed evaluation as per our unit ***(11-year-boy)amongst the 3 patients had complete KD,while the other two(3.3-year-boy;4-month-girl)had incomplete *** revealed separate origins of left anterior descending artery and left circumflex from left sinus[misinterpreted as dilated left main coronary artery(lCA)on 2DE],single coronary artery(interpreted as dilated lCA on 2DE)and dilated right coronary artery on 2DE in case of anomalous origin of lCA from the main pulmonary *** latter one was subsequently operated *** CTCA is essential for detailed assessment of coronary arteries in children with KD especially in cases where there is suspicion of congenital coronary artery *** solely on 2DE may not be sufficient in such cases,and findings from CTCA can significantly impact therapeutic decision-making.

关键词： Coronary artery abnormalities Congenital coronary artery anomalies Computed tomography coronary angiography Kawasaki disease 2-dimensional echocardiography

Interest of D-dimer level,severity of COVID-19 and cost of management in Gabon

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World Journal of Critical Care Medicine 2025年第1期14卷 91-99页

作者： Berthe A Iroungou Arnaud Nze O Helga M Kandet Y Neil-Michel longo-Pendy Nina D Mezogho-Obame Annicet-Clotaire Dikoumba Guignali l Mangouka UnitéMixte de Recherche Centre International de Recherches Médicales de Franceville et le Service de SantéMilitaireLibreville 20404EstuaireGabon AP-HP Health Economics Research UnitHtel Dieu HospitalParis 75004Ilede-FranceFrance laboratory Hôpital D'Instruction des Armées D'AkandaLibreville 20404EstuaireGabo Unitéde Recherche enÉcologie de la Santé Centre Interdisciplinaire de Recherches Médicales de FrancevilleFranceville 769Gabon laboratory Hôpital D'Instruction des Armées Omar Bongo OndimbaLibreville 20404EstuaireGabon Department of Medecine Polyvalente Hôpital D'Instruction des Armées Omar Bongo OndimbaLibreville 20404EstuaireGabon

BACKGROUND Coronavirus disease 2019(COVID-19)is strongly associated with an increased risk of thrombotic events,including severe outcomes such as pulmonary *** D-dimer levels are a critical biomarker for assessing this *** Gabon,early implementation of anticoagulation therapy and D-dimer testing has been crucial in managing *** study hypothesizes that elevated Ddimer levels are linked to increased COVID-19 *** To determine the impact of D-dimer levels on COVID-19 severity and their role in guiding clinical *** This retrospective study analyzed COVID-19 patients admitted to two hospitals in Gabon between March 2020 and December *** study included patients with confirmed COVID-19 diagnoses and available D-dimer measurements at *** on demographics,clinical outcomes,D-dimer levels,and healthcare costs were ***-19 severity was classified as non-severe(outpatients)or severe(inpatients).A multivariable logistic regression model was used to assess the relationship between D-dimer levels and disease severity,with adjusted odds ratios(OR)and 95%*** A total of 3004 patients were included,with a mean age of 50.17 years,and the majority were female(53.43%).Elevated D-dimer levels were found in 65.81%of patients,and 57.21%of these experienced severe *** analysis showed that patients with elevated D-dimer levels had 3.33 times higher odds of severe COVID-19(OR=3.33,95%CI:2.84-3.92,Pltivariable analysis,adjusted for age,sex,and year of *** financial analysis revealed a substantial burden,particularly for uninsured *** D-dimer predicts COVID-19 severity and guides treatment,but the high cost of anticoagulant therapy highlights the need for policies ensuring affordable access in resource-limited settings like Gabon.

关键词： D-dimers COVID-19 Management Disease severity Healthcare costs Gabon

Analytic Study of Spinal Infections: Clinical Picture, Treatment, and Outcomes in King Fahad Military Medical Complex in Dhahran, Saudi Arabia

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Open Journal of Medical Microbiology 2020年第3期10卷 103-113页

作者： Salma Albahrani Amal Shilash ayat Albasri Sharifah Almuthen Sama Tawfiq Khalid Alzahrani Amjad Darwish Muneera Albassam Jamil Barhoun King Fahad Military Complex Dhahran KSA Infectious Disease Consultant King Fahad Military Complex Dhahran KSA Epidemiologist Infection Control Department King Fahad Military Complex Dhahran KSA Internal Medicine Department King Fahad Military Complex Dhahran KSA Neurosurgeon Consultant King Fahad Military Complex Dhahran KSA Radiology Department King Fahad Military Complex Dhahran KSA

Objective: To evaluate the prevalence of spinal infection in a hospital located in the eastern region of Saudi Arabia through a retrospective review and to identify the associated etiological agents in terms of clinic... 详细信息

le="line-height:1.5;">Objective: To evaluate the prevalence of spinal infection in a hospital located in the eastern region of Saudi Arabia through a retrospective review and to identify the associated etiological agents in terms of clinical picture, treatment, and outcomes. Design: Retrospective cross-sectional study. Setting: Single hospital in Dhahran, Saudi Arabia. Patients: Patients with any type of spinal infection and/or who had undergone neurosurgical intervention for spinal infection between January 2006 and December 2018. Methods: We collected data on all patients with an established diagnosis of spinal infection from January 2006 to December 2018 in the King Fahad Military Medical Complex in Dhahran, Saudi Arabia. A validated and structured checklist was used for data collection. Spinal infection diagnosis was based on the clinical manifestation, microbiological evidence, radiological findings, and antimicrobial therapy response. Results: Seventeen patients were included in this study, and their mean age was 54.93 years. Twelve of the patients were male and four were female. The approximate time from symptom onset to diagnosis was 2 - le="line-height:1.5;font-family:Verdana;">6 months. Most of the patients experienced back pain, with lumbosacral spondylitis being the most commonly cited type (61.11%

关键词： Spinal Infection Mycobacterium tuberculosis Quambalaria cyanescens Tuberculosis Spondylodiscitis

Experimental study on reduction of U (Ⅵ) by an anaerobic bacterium, Shewanella putrefaciens: Application to sandstone-hosted interlayer oxidation-zone type uranium deposits, China

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Science China Earth Sciences 2005年第3期48卷 346-352页

作者： l.l.Barton Department of Biology University of New Mexico Albuquerque NM 87131-1116USA

An experimental study on reduction of U (VI) by anaerobic bacteria, Shewanella putrefaciens, is first reported here in China. The experimental conditions were: 35℃ and pH = 7.0—7.4, corresponding to a physicochemical environments in which the sandstone-hosted in- terlayer oxidation-zone type uranium deposit formed in Northwest China’s Xinjiang. Bacteria adopted in the present experiment, Shewanella putrefaciens, occur extensively in natural envi- ronment. Our study shows that nano-crystal precipitates of uraninite quickly occurred on the surface of the cells within one week. It was found that the pitchblende was characterized by a random arrangement of uraninite nanocrystals (2—4 nm) in it, significantly different from natural pitchblende in which uraninite nanocrystals are arranged in order. Finally, a possible mechanism of uranium biomineralization by microorganisms in the deposits is discussed. Our investigation may supply a technical train of thoughts for bioremediation of nuclear-contaminated water envi- ronments and for underground dissolving extraction of the sandstone-hosted uranium ores.

关键词： anaerobic bacteria, reduction, pitchblende, sandstone-hosted uranium deposit, experimental study.

Complement-dependent neuroinflammation in spinal cord injury:from pathology to therapeutic implications

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Neural Regeneration Research 2025年第5期20卷 1324-1335页

作者： Hassan Saad Bachar El Baba Ali Tfaily Firas Kobeissy Juanmarco Gutierrez Gonzalez Daniel Refai Gerald R.Rodts Christian Mustroph David Gimbel Jonathan Grossberg Daniel l.Barrow Matthew F.Gary Ali M.Alawieh Department of Neurosurgery Emory University School of MedicineAtlantaGAUSA Department of Neurology Yale UniversityNew HavenCTUSA Center for Neurotrauma Multiomics&Biomarkers(CNMB)Morehouse School of MedicineAtlantaGAUSA

Spinal cord injury remains a major cause of disability in young adults,and beyond acute decompression and rehabilitation,there are no pharmacological treatments to limit the progression of injury and optimize recovery in this *** the thorough investigation of the complement system in triggering and propagating cerebral neuroinflammation,a similar role for complement in spinal neuroinflammation is a focus of ongoing *** this work,we survey the current literature investigating the role of complement in spinal cord injury including the sources of complement proteins,triggers of complement activation,and role of effector functions in the *** study relevant data demonstrating the different triggers of complement activation after spinal cord injury including direct binding to cellular debris,and or activation via antibody binding to damage-associated molecular *** effector functions of complement have been implicated in spinal cord injury,and we critically evaluate recent studies on the dual role of complement anaphylatoxins in spinal cord injury while emphasizing the lack of pathophysiological understanding of the role of opsonins in spinal cord *** this pathophysiological review,we systematically review the different translational approaches used in preclinical models of spinal cord injury and discuss the challenges for future translation into human *** review emphasizes the need for future studies to dissect the roles of different complement pathways in the pathology of spinal cord injury,to evaluate the phases of involvement of opsonins and anaphylatoxins,and to study the role of complement in white matter degeneration and regeneration using translational strategies to supplement genetic models.

关键词： complement neuroinflammation neuroplasticity regeneration spinal cord injury targeted therapy

Three-dimensional dynamics of supported pipes conveying fluid

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Acta Mechanica Sinica 2017年第6期33卷 1065-1074页

作者： l.Wang T.l.Jiang H.l.Dai Department of Mechanics Huazhong University of Science and Technology Wuhan 430074 China Hubei Key laboratory for Engineering Structural Analysis and Safety Assessment Wuhan 430074 China

This paper deals with the three-dimensional dynamics and postbuckling behavior of flexible supported pipes conveying fluid, considering flow velocities lower and higher than the critical value at which the buckling instability occurs. In the case of low flow velocity, the pipe is stable with a straight equilibrium position and the dynamics of the system can be examined using linear theory. When the flow velocity is beyond the critical value, any motions of the pipe could be around the postbuckling configuration(non-zero equilibrium position) rather than the straight equilibrium position, so nonlinear theory is required. The nonlinear equations of perturbed motions around the postbuckling configuration are derived and solved with the aid of Galerkin discretization. It is found, for a given flow velocity,that the first-mode frequency for in-plane motions is quite different from that for out-of-plane motions. However, the second-or third-mode frequencies for in-plane motions are approximately equal to their counterparts for out-of-plane motions, keeping almost constant values with increasing flow velocity. Moreover, the orientation angle of the postbuckling configuration plane for a buckled pipe can be significantly affected by initial conditions, displaying new features which have not been observed in the same pipe system factitiously supposed to deform in a single plane.

关键词： Pipe conveying fluid Three-dimensional dynamics Instability Natural frequency Postbuckling configuration

The dynamic compensation temperature in a kinetic spin-5/2 Ising model on a hexagonal lattice

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Chinese Physics B 2013年第3期22卷 471-480页

作者： mt Temizer Aysegl Ozkιlι Department of Physics Bozok University66200 YozgatTurkey Institute of Science Bozok University66200 YozgatTurkey

We present a study of the dynamic behavior of a two-sublattice spin-5/2 Ising model with bilinear and crystal-field interactions in the presence of a time-dependent oscillating external magnetic field on alternating layers of a hexagonal lattice by using the Glauber-type stochastic *** lattice is formed by alternate layers of spins σ=5/2 and S=5/*** employ the Glauber transition rates to construct the mean-field dynamic ***,we investigate the time variations of the average sublattice magnetizations to find the phases in the system and then the thermal behavior of the dynamic sublattice magnetizations to characterize the nature（first-or second-order） of the phase transitions and to obtain the dynamic phase transition（DPT） *** also study the thermal behavior of the dynamic total magnetization to find the dynamic compensation temperature and to determine the type of the dynamic compensation *** present the dynamic phase diagrams,including the dynamic compensation temperatures,in nine different *** phase diagrams contain seven different fundamental phases,thirteen different mixed phases,in which the binary and ternary combination of fundamental phases and the compensation temperature or the l-type behavior strongly depend on the interaction parameters.

关键词： kinetic Ising model dynamic phase transition dynamic compensation temperature

DIPOlE POlARIZATION RElAXATION AND MOlECUlAR STRUCTURE OF MAIN-AND SIDE-CHAIN lIQUID-CRYSTAllINE POlYMERS

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Chinese Journal of Polymer Science 1996年第1期14卷 1-18页

作者： T.P.Stepanova l.l.Burshtein Institute of Macromolecular Compounds of Russian Academy of Sciences Bolshoy pr. 31 St. Petersburg 199004 RussiaInstitute of Macromolecular Compounds of Russian Academy of Sciences Bolshoy pr. 31 St. Petersburg 199004 Russia

Molecular mobility in thermotropic polyesters and side-chain polymers with different struc-ture of mesogens and spacers has been studied by dielectrical method in dilutesolutions. The results made it possible to establish the multiplicity of dielectric relaxationtransitions which reflects the small- and large-scale types of molecular motion. It was shownthat dielectric relaxation processes occurring in accordance with local mechanism (relaxationtimes 10^(-9)--10^(-7)s. and the activation energy 10--50kJ/mol) are due to the mobility of kineticchain elements of different length within a monomer units. It was found that the dielectricrelaxation process connected with a large-scale form of molecular motion (relaxation times10^(-5)--10^(-6)s. and the activation energy 100kJ/mol) did not depend on the molecular massbut was infiuenced by factors changing the conformational state of the macromolecule. It isestablished tha the cooperative reorientation mobility of associated mesogenic fragments isthe source of the large-scale process.

关键词： liquid crystal polymers Dielectric polarization Relaxation transitions Dilute solution Aggregation