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Intelligent speed adaptation for visibility technology affects drivers’speed selection along curves with sight limitations

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Journal of Traffic and Transportation Engineering(English Edition) 2024年第1期11卷 16-27页

作者： Abrar Hazoor Alberto Terrafino l.andro l.Di Stasi Marco Bassani Department of Environment Landand Infrastructure EngineeringPolitecnico di TorinoTorino 10129Italy Road Traffic Division Nord UniversityStjørdal 7502Norway Mind Brainand Behavior Research Centre(CIMCYC)University of GranadaGranada 18071Spain

Sight obstructions along road curves can lead to a crash if the driver is not able to stop the vehicle in time.This is a particular issue along curves with limited available sight,where speed management is necessary to avoid unsafe situations(e.g.,driving off the road or invading the other traffic lane).To solve this issue,we proposed a novel intelligent speed adaptation(ISA)system for visibility,called V-ISA(intelligent speed adaptation for visibility).It estimates the real-time safe speed limits based on the prevailing sight conditions.V-ISA comes with three variants with specific feedback modalities(1)visual.and(2)auditory information,and(3)direct intervention to assume control over the vehicle speed.Here,we investigated the efficiency of each of the three V-ISA variants on driving speed choice and lateral behavioural response along road curves with limited and unsafe available sight distances,using a driving simulator.We also considered curve road geometry(curve direction:rightward vs.leftward).Sixty active drivers were recruited for the study.While half of them(experimental group)tested the three V-ISA variants(and a V-ISA off condition),the other half always drove with the V-ISA off(validation group).We used a linear mixed-effect model to evaluate the influence of V-ISA on driver behaviour.All V-ISA variants were efficient at reducing speeds at entrance points,with no discernible negative impact on driver lateral behaviour.On rightward curves,the V-ISA intervening variant appeared to be the most effective at adapting to sight limitations.Results of the current study implies that V-ISA might assist drivers to adjust their operating speed as per prevailing sight conditions and,consequently,establishes safer driving conditions.

关键词： Sight distance Intelligent speed adaptation Driver behaviour Road safety Driving simulation Advanced driver assistance systems

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Deep bed filtration model for cake filtration and erosion

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Applied Mathematics and Mechanics(English Edition) 2024年第2期45卷 355-372页

作者： l.I.KUZMINA Y.V.OSIPOV A.R.PESTEREV Department of Applied Mathematics HSE UniversityMoscow 101000Russia Department of Computer Science and Applied Mathematics Moscow State University of Civil EngineeringMoscow 129337Russia

Many phenomena in nature and technology are associated with the filtration of suspensions and colloids in porous media. Two main types of particle deposition,namely, cake filtration at the inlet and deep bed filtration throughout the entire porous medium, are studied by different models. A unified approach for the transport and deposition of particles based on the deep bed filtration model is proposed. A variable suspension flow rate, proportional to the number of free pores at the inlet of the porous medium, is considered. To model cake filtration, this flow rate is introduced into the mass balance equation of deep bed filtration. For the cake filtration without deposit erosion,the suspension flow rate decreases to zero, and the suspension does not penetrate deep into the porous medium. In the case of the cake filtration with erosion, the suspension flow rate is nonzero, and the deposit is distributed throughout the entire porous medium. An exact solution is obtained for a constant filtration function. The method of characteristics is used to construct the asymptotics of the concentration front of suspended and retained particles for a filtration function in a general form. Explicit formulae are obtained for a linear filtration function. The properties of these solutions are studied in detail.

关键词： deep bed filtration cake filtration porous medium particle deposition and erosion analytical solution concentration front

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Utilization of RNA sequencing to investigate olfactory dysfunction in chronic rhinosinusitis without nasal polyps:A pilot study

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 29-36页

作者： Jorge A.Gutierrez III Jeremy l.Barth Rodney J.Schlosser Thomas S.Edwards Timothy l.Smith Zachary M.Soler Department of Otolaryngology-Head and Neck Surgery Medical University of South CarolinaCharlestonSouth CarolinaUSA Department of Regenerative Medicine&Cell Biology Medical University of South CarolinaCharlestonSouth CarolinaUSA Department of Otolaryngology-Head and Neck Surgery Oregon Health&Science UniversityPortlandOregonUSA

Objectives:Prior research on olfactory dysfunction in chronic rhinosinusitis(CRS)has focused on patients with polyps and suggests that direct inflammation of the olfactory cleft mucosa plays a contributory role.The purpose of this study was to evaluate gene expression in superior turbinate mucosal specimens,comparing normosmic and dysosmic CRS patients without polyps(CRSsNP).Methods:Tissue samples were obtained from the superior turbinates of patients with CRSsNP at the time of endoscopic sinus surgery.Samples subsequently underwent RNA sequencing and functional.analysis to investigate biological pathways associated with differentially expressed genes between dysosmic(n=7)and normosmic(n=4)patients.Results:Differential gene expression analysis comparing dysosmic and normosmic CRSsNP patients showed upregulation of 563 genes and downregulation of 327 genes.Using stringent criteria for multiple comparisons,one upregulated gene(Immediate Early Response 3[IER3])had an false discovery rate(FDR)correction adjustedP value considered statistically significant(Pld change 2.69).Reactome functional.analysis revealed eight biological pathways significantly different between dysosmic and normosmic patients(Pluding Il-4 and Il-13 signaling,Il-10 signaling,and rhodopsin-like receptors.Conclusions:RNA sequencing of the superior turbinates in patients with CRSsNP can provide valuable information regarding biological pathways and genes involved in olfactory dysfunction.This study supports literature suggesting that Type 2 inflammation may play a role in olfactory dysfunction in at least some patients with CRSsNP.This study also prompts questions regarding the role of Il-10,rhodopsin-like receptors,andIER3 in the pathogenesis of olfactory dysfunction.

关键词： chronic rhinosinusitis without nasal polyps olfactory dysfunction RNA sequencing

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Control Policy learning Design for Vehicle Urban Positioning via BeiDou Navigation

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Journal of Systems Science & Complexity 2024年第1期37卷 114-135页

作者： QIN Yahang ZHANG Chengye CHEN Ci XIE Shengli lEWIS Frank l School of Automation Guangdong University of TechnologyGuangzhou 510006China Guangdong Key laboratory of IoT Information Technology Guangzhou 510006China. Center for Intelligent Batch Manufacturing Based on IoT Technology Key laboratory of Intelligent Detection and The Internet of Things in Manufacturing Ministry of EducationGuangzhou 510006China Guangdong-HongKong-Macao Joint laboratory for Smart Discrete Manufacturing Guangzhou 510006China Key laboratory of Intelligent Information Processing and System Integration of IoT Ministry of EducationGuangzhou 510006China. UTA Research Institute The University of Texas at ArlingtonFort WorthTX 76019USA

This paper presents a learning-based control policy design for point-to-point vehicle positioning in the urban environment via BeiDou navigation.While navigating in urban canyons,the multipath effect is a kind of interference that causes the navigation signal to drift and thus imposes severe impacts on vehicle localization due to the reflection and diffraction of the BeiDou signal.Here,the authors formulated the navigation control system with unknown vehicle dynamics into an optimal control-seeking problem through a linear discrete-time system,and the point-to-point localization control is modeled and handled by leveraging off-policy reinforcement learning for feedback control.The proposed learning-based design guarantees optimality with prescribed performance and also stabilizes the closed-loop navigation system,without the full knowledge of the vehicle dynamics.It is seen that the proposed method can withstand the impact of the multipath effect while satisfying the prescribed convergence rate.A case study demonstrates that the proposed algorithms effectively drive the vehicle to a desired setpoint under the multipath effect introduced by actual experiments of BeiDou navigation in the urban environment.

关键词： BeiDou navigation multipath effect prescribed convergence rate reinforcement learning urban localization.

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Two-Stream Approximation to the Radiative Transfer Equation:A New Improvement and Comparative Accuracy with Existing Methods

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Advances in Atmospheric Sciences 2024年第2期41卷 278-292页

作者： F.Momo TEMGOUA l.Akana NGUIMDO DNJOMO Environmental Energy Technologies laboratory(EETl) Faculty of SciencesUniversity of YaoundéPO Box 812 YaoundéCameroon Department of Electrical.and Electronic Engineering Faculty of Engineering and TechnologyUniversity of BueaPO Box 63 BueaCameroon

Mathematical modeling of the interaction between solar radiation and the Earth's atmosphere is formalized by the radiative transfer equation(RTE), whose resolution calls for two-stream approximations among other methods. This paper proposes a new two-stream approximation of the RTE with the development of the phase function and the intensity into a third-order series of legendre polynomials. This new approach, which adds one more term in the expression of the intensity and the phase function, allows in the conditions of a plane parallel atmosphere a new mathematical formulation of γparameters. It is then compared to the Eddington, Hemispheric Constant, Quadrature, Combined Delta Function and Modified Eddington, and second-order approximation methods with reference to the Discrete Ordinate(Disort) method(δ –128 streams), considered as the most precise. This work also determines the conversion function of the proposed New Method using the fundamental definition of two-stream approximation(F-TSA) developed in a previous work. Notably,New Method has generally better precision compared to the second-order approximation and Hemispheric Constant methods. Compared to the Quadrature and Eddington methods, New Method shows very good precision for wide domains of the zenith angle μ 0, but tends to deviate from the Disort method with the zenith angle, especially for high values of optical thickness. In spite of this divergence in reflectance for high values of optical thickness, very strong correlation with the Disort method(R ≈ 1) was obtained for most cases of optical thickness in this study. An analysis of the legendre polynomial series for simple functions shows that the high precision is due to the fact that the approximated functions ameliorate the accuracy when the order of approximation increases, although it has been proven that there is a limit order depending on the function from which the precision is lost. This observation indicates that increasing the order of approximation of the phase function of the RTE lead

关键词： Radiative Transfer Equation two-stream method legendre polynomial optical thickness moments of specific intensity conversion function transmittance reflectance

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Exploring unconventional attributes of red blood cells and their potential applications in biomedicine

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Protein & Cell 2024年第5期15卷 315-330页

作者： Alkmini T.Anastasiadi Vasiliki-Zoi Arvaniti Krystalyn E.Hudson Anastasios G.Kriebardis Constantinos Stathopoulos Angelo D’Alessandro Steven l.Spitalnik Vassilis l.Tzounakas Department of Biochemistry School of MedicineUniversity of Patras26504 PatrasGreece Department of Pathology and Cell Biology Columbia University Irving Medical CenterNew York CityNY 10032USA laboratory of Reliability and Quality Control in laboratory Hematology(HemQcR) Department of Biomedical SciencesSchool of Health&Caring SciencesUniversity of West Attica(UniWA)12243 EgaleoGreece Department of Biochemistry and Molecular Genetics University of Colorado Anschutz Medical Campus13001 AuroraCOUSA Present address:Institute for Fundamental Biomedical Research(IFBR) Biomedical Sciences Research Center“Alexander Fleming”Vari11527 AthensGreece

We need to talk about red blood cells.Eukaryotic cells are defined as cells containing distinct nuclei and other membranous organelles.However,red blood cells(RBCs)lack a nucleus and organelles—perhaps to limit the generation of reactive oxygen species(Zhang et al.,2011)—and are filled with hemoglobin(Hb).This oxygen carrier is limited to the cytosol by the cell membrane and cytoskeleton,which maintain cellular integrity and deformability as RBCs pass through narrow capillaries(Gratzer,1994)to perform their primary function of gas exchange.

关键词： al. membranous maintain

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Zassenhaus lemma,Schreier Refinement Theorem,and Jordan–Hölder Theorem for Gyrogroups

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Algebra Colloquium 2024年第2期31卷 323-332页

作者： Prathomjit Khachorncharoenkul Rasimate Maungchang Teerapong Suksumran l.A.Bokut School of Science Walailak UniversityNakhon Si Thammarat 80160Thailand Department of Mathematics Faculty of ScienceChiang Mai University Chiang Mai 50200Thailand 不详

In this article,we extend the Zassenhaus lemma(also called the butterfly lemma)and the Schreier refinement theorem to the case of gyrogroups.In addition,we use these results to prove the Jordan–Hölder theorem for gyr... 详细信息

关键词： Zassenhaus lemma Schreier refinement theoremg yrogroup subgyrogroup diagram normal subgyrogroup

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A flexible,thin-film microchannel electrode array device for selective subdiaphragmatic vagus nerve recording

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Microsystems & Nanoengineering 2024年第1期10卷 115-128页

作者： Jongcheon lim Peter A.Zoss Terry l.Powley Hyowon lee Matthew P.Ward Weldon School of Biomedical Engineering Purdue UniversityWest LafayetteINUSA Birck Nanotechnology Center Purdue UniversityWest LafayetteINUSA Center for Implantable Devices Purdue UniversityWest LafayetteINUSA Department of Psychological Sciences Purdue UniversityWest LafayetteINUSA Purdue Institute of Integrative Neuroscience Purdue UniversityWest LafayetteINUSA Indiana University School of Medicine IndianapolisINUSA

The vagus nerve(VN)plays an important role in regulating physiological conditions in the gastrointestinal(GI)tract by communicating via the parasympathetic pathway to the enteric nervous system(ENS).However,the lack of knowledge in the neurophysiology of the VN and GI tract limits the development of advanced treatments for autonomic dysfunctions related to the VN.To better understand the complicated underlying mechanisms of the VN-GI tract neurophysiology,it is necessary to use an advanced device enabled by microfabrication technologies.Among several candidates including intraneural probe array and extraneural cuff electrodes,microchannel electrode array devices can be used to interface with smaller numbers of nerve fibers by securing them in the separate channel structures.Previous microchannel electrode array devices to interface teased nerve structures are relatively bulky with thickness around 200µm.The thick design can potentially harm the delicate tissue structures,including the nerve itself.In this paper,we present a flexible thin film based microchannel electrode array device(thickness:11.5µm)that can interface with one of the subdiaphragmatic nerve branches of the VN in a rat.We demonstrated recording evoked compound action potentials(ECAP)from a transected nerve ending that has multiple nerve fibers.Moreover,our analysis confirmed that the signals are from C-fibers that are critical in regulating autonomic neurophysiology in the GI tract.

关键词： electrode recording film

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Portable dielectrophoresis for biology:ADEPT facilitates cell trapping,separation,and interactions

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Microsystems & Nanoengineering 2024年第2期10卷 193-205页

作者： lourdes Albina Nirupa Julius Dora Akgül Gowri Krishnan Fabian Falk Jan Korvink Vlad Badilita Department Institute of Microstructure TechnologyKarlsruhe Institute of TechnologyHermann-von-Helmholtz-Platz 1Eggenstein-Leopoldshafen76344Baden-WürttembergGermany

Dielectrophoresis is a powerful.and well-established technique that allows label-free,non-invasive manipulation of cells and particles by leveraging their electrical properties.The practical implementation of the associated electronics and user interface in a biology laboratory,however,requires an engineering background,thus hindering the broader adoption of the technique.In order to address these challenges and to bridge the gap between biologists and the engineering skills required for the implementation of DEP platforms,we report here a custom-built,compact,universal electronic platform termed ADEPT(adaptable dielectrophoresis embedded platform tool)for use with a simple microfluidic chip containing six microelectrodes.The versatility of the open-source platform is ensured by a custom-developed graphical user interface that permits simple reconfiguration of the control signals to address a wide-range of specific applications:(i)precision positioning of the single bacterium/cell/particle in the micrometer range;(ii)viability-based separation by achieving a 94%efficiency in separating live and dead yeast;(iii)phenotype-based separation by achieving a 96%efficiency in separating yeast and Bacillus subtilis;(iv)cell–cell interactions by steering a phagocytosis process where a granulocyte engulfs E.coli RGB-S bacterium.Together,the set of experiments and the platform form a complete basis for a wide range of possible applications addressing various biological questions exploiting the plug-and-play design and the intuitive GUI of ADEPT.

关键词： Together separation separating

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Nonreciprocal generation of Schrodinger cat state induced by topology

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Science China(Physics,Mechanics & Astronomy) 2024年第4期67卷 23-30页

作者： Zi-Hao li li-li Zheng Ying Wu Xin-You lü School of Physics and Institute for Quantum Science and Engineering Huazhong University of Science and Technologyand Wuhan Institute of Quantum TechnologyWuhan 430074China Key laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education Jianghan UniversityWuhan 430074China

The Schrodinger cat state produced differently in two directions is anticipated to be a critical quantum resource in quantum information technologies.By exploring the interplay between quantum nonreciprocity and topology in a one-dimensional microcavity array,we obtain the Schrodinger cat state(a pure quantum state)in a chosen direction at the edge cavity,whereas a classical state in the other direction.This nonreciprocal generation of the cat state originates from the topologically protected chiralitymode excitation in the nontrivial phase,but in the trivial phase,the nonreciprocal generation of cat state vanishes.Thus,our proposal is switchable by tuning the parameters so that a topological phase transition occurs.Moreover,the obtained cat state has nonreciprocal high fidelity,nonclassicality,and quantum coherence,which are sufficient to be used in various one-way quantum technologies,e.g.,invisible quantum sensing,noise-tolerant quantum computing,and chiral quantum networks.Our work provides a general approach to control quantum nonreciprocities with the topological effect,which substantially broadens the fields of nonreciprocal photonics and topological physics.

关键词： Schr?dinger cat state nonreciprocity topology

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