检索结果-南通市图书馆

COVID-19:Reducing the risk via diet and lifestyle

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Medicine 2023年第1期21卷 1-16页

作者： Jessica l.Campbell 160 Goat Island Road LeighAuckland 0985New Zealand

This review shows that relatively simple changes to diet and lifestyle can significantly,and rapidly,reduce the risks associated with coronavirus disease 2019(COVID-19)in terms of infection risk,severity of disease,and even disease-related mortality.A wide range of interventions including regular exercise,adequate sleep,plant-based diets,maintenance of healthy weight,dietary supplementation,and time in nature have each been shown to have beneficial effects for supporting more positive health outcomes with COVID-19,in addition to promoting better overall health.This paper brings together literature from these areas and presents the argument that non-pharmaceutical approaches should not be overlooked in our response to COVID-19.It is noted that,in several cases,interventions discussed result in risk reductions equivalent to,or even greater than,those associated with currently available vaccines.Where the balance of evidence suggests benefits,and the risk is minimal to none,it is suggested that communicating the power of individual actions to the public becomes morally imperative.Further,many lives could be saved,and many harms from the vaccine mandates avoided,if we were willing to embrace this lifestyle-centred approach in our efforts to deal with COVID-19.

关键词： COVID-19 SARS-CoV-2 Exercise Sleep Diet Risk reduction behaviour

Humanization for neurological disease modeling:A roadmap to increase the potential of Drosophila model systems

在线全文

学校读者我要写书评

暂无评论

Animal Models and Experimental Medicine 2023年第3期6卷 230-236页

作者： Vladimir l.Katanaev Department of Cell Physiology and Metabolism Faculty of MedicineUniversity of GenevaGenevaSwitzerland HumanaFly Facility Faculty of MedicineUniversity of GenevaGenevaSwitzerland

Neuroscience and neurology research is dominated by experimentation with rodents.Around 75%of neurology disease-associated genes have orthologs in Drosophila meL.Anogaster,the fruit fly amenable to complex neurologicaL.And behavioral investiga-tions.However,non-vertebrate models including Drosophila have so far been unable to significantly replace mice and rats in this field of studies.One reason for this situ-ation is the predominance of gene overexpression(and gene loss-of-function)meth-odologies used when establishing a Drosophila model of a given neurological disease,a strategy that does not recapitulate accurately enough the genetic disease condi-tions.I argue here the need for a systematic humanization approach,whereby the Drosophila orthologs of human disease genes are replaced with the human sequences.This approach will identify the list of diseases and the underlying genes that can be adequately modeled in the fruit fly.I discuss the neurological disease genes to which this systematic humanization approach should be applied and provide an example of such an application,and consider its importance for subsequent disease modeling and drug discovery in Drosophila.I argue that this paradigm will not only advance our un-derstanding of the molecular etiology of a number of neurological disorders,but will also gradually enable researchers to reduce experimentation using rodent models of multiple neurological diseases and eventually replace these models.

关键词： disease modeling Drosophila humanization neurological diseases

Principal Value and Its Applications for One Type of Cauchy–FantappièIntegraL.And the System of Equations

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2022年第9期38卷 1537-1550页

作者： lüPing CHEN School of Mathematical Sciences Xiamen UniversityXiamen 361005P.R.China

It is known that principal value plays vital roles in the study of singular integral.In this paper,one type of Cauchy–Fantappièintegral with multiple indexes is introduced.Since the structure of the kernel is complexity,the Jacobian determinant included in the kernel is expanded for making clearly the expression of the kernel.Moreover,one differential operator is utilized for setting up relations between integrals with higher and usual orders.The work also concerns the convergent properties of the integral.In order to study Hadamard principal value and composite formula of this integral,finite and divergent parts will be estimated and separated.As an application,solvability of the system of integral equations with higher order singularity kernel is discussed.

关键词： Principal value Cauchy–Fantappièintegral piecewise smooth manifold differential operator system of singular integral equation

A movable beast: glaciation in the Ediacaran

在线全文

学校读者我要写书评

暂无评论

National Science Review 2023年第8期10卷 119-120页

作者： Joseph l. Kirschvink The Marine Core Research Institute Kochi University Division of Geological&Planetary Sciences California Institute of Technology

Ediacaran time(635–543 million years ago [Ma]) represents the dawn of macroscopic life following two Neoproterozoic Snowball Earth episodes [1], where a runaway ice-albedo effect caused the entire planet to become en... 详细信息

关键词： TRUE POlAR WANDER

Iterative analytic extension in tomographic imaging

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Visual Computing for Industry,Biomedicine,and Art 2022年第1期5卷 44-56页

作者： Gengsheng l.Zeng Department of Computer Science Utah Valley UniversityOremUT 84058USA Department of Radiology and Imaging Sciences University of UtahSalt Lake CityUT 84108USA

If a spatial-domain function has a finite support,its Fourier transform is an entire function.The Taylor series expansion of an entire function converges at every finite point in the complex plane.The analytic continuation theory suggests that a finite-sized object can be uniquely determined by its frequency components in a very small neighborhood.Trying to obtain such an exact Taylor expansion is difficult.This paper proposes an iterative algorithm to extend the measured frequency components to unmeasured regions.Computer simulations show that the proposed algorithm converges very slowly,indicating that the problem is too ill-posed to be practically solvable using available methods.

关键词： Analytic continuation Entire function Iterative projections onto convex sets algorithm Image reconstruction limited angle tomography

HIl testing of wheel slide protection systems:criteria for continuous updating and validation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Railway Engineering Science 2023年第2期31卷 108-121页

作者： l.Pugi G.Paolieri M.Giorgetti l.Berzi R.Viviani l.Cabrucci l.Bocciolini Department of Industrial Engineering University of FlorenceVia di Santa Marta 350139 FlorenceItaly Italcertifer SPA(TEST CENTER) Via Curzio Malaparte850145 FlorenceItaly

Assessment of railway wheel slide protection(WSP) systems involves the execution of complex experimental activities that are quite expensive and time-consuming, since they involve the physical reproduction of degraded adhesion conditions on a real railway line. WSP is devoted to regulating applied braking forces to avoid excessive wheel sliding in case of degraded adhesion conditions between wheeL.And rail. WSP must be also compL.Ant to safety specifications related to assured braking performances and consumed air. Hardware in the loop(HIl) testing offers an affordable and sustainable way to accelerate these activities optimizing cost, duration and safety of experimental activities performed online. HIl test rigs are subjected to continuous updates, customization and natural ageing of their components. This work investigates the criteria that can be adopted to assure a continuous monitoring and validation of a real WSP test rig, the ItaL.An test rig of Firenze Osmannoro.

关键词： Hardware in the loop(HIl) Wheel slide protection(WSP) Degraded adhesion conditions Train brake

Progress in perisynaptic Schwann celL.And neuromuscular junction research

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第6期17卷 1273-1274页

作者： Chandler l.Walker Department of Biomedical Sciences and Comprehensive Care Indiana University School of DentistryNeuromusculoskeletal Research GroupRichard L.Roudebush Veterans Affairs Medical CenterIndianapolisINUSA

The neuromuscular junction(NMJ)is widely studied for its utility in investigating synaptic properties and processes and neuromuscular changes in response to injury,aging,and disease.The NMJ consists of three essentiaL.Anatomic components,the pre-synaptic motor axon terminal,the post-synaptic nicotinic acetylcholine receptors(AchRs)on the muscle,and the perisynaptic Schwann cell(PSC),also known as the terminal Schwann cell,that caps the synapse(Figure 1A).

关键词： aging Figure utility

Brain-machine-brain interfaces as the foundation for the next generation of neuroprostheses

在线全文

学校读者我要写书评

暂无评论

National Science Review 2022年第10期9卷 8-10页

作者： Miguel A.l.Nicolelis Department of Neurobiology Duke University International Institute of Neuroscience Edmond and lily Safra

Back in 2011,my laboratory at the Duke University Center for Neuroengineering proposed a new variation on the already-classic paradigm known as brain-machine interfaces (BMIs)[1].In a series of experiments [2],we showed that monkeys could not only learn to employ electrical signals from large neuronal ensembles (300-700 neurons)located in the primary motor cortex(M1) to control the movements of an avatar arm and hand—i.***.using a typical BMI paradigm—but that they could also interpret in real time,streams of electrical signals delivered directly to their primary somatosensory cortex (S1) via cortical microstimulation.This strategy was created to allow these monkeys to perform a tactile discrimination task,without any interference from their physical bodies.Thus,instead of using their real finger tips to perform such a task,this approach allowed our monkeys to use their brain activity to directly control the movements of’virtual finger tips to scan the texture of a series of virtual objects.Upon receiving,via cortical microstimulation,electrical signals directly into their S1 that were proportional to the virtual surface textures of these objects,the monkeys learned to quickly select the correct object that they needed to identify to receive a reward.Essentially,

关键词： SPINAl-CORD STIMUlATION

Complex-frequency waves:beat loss and win sensitivity

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

light(Science & Applications) 2024年第2期13卷 181-183页

作者： Qingqing Cheng Tao l School of Optical-ElectricaL.And Computer Engineering University of Shanghai for Science and TechnologyShanghai200093China Department of Respiratory Diseases and Critical Medicine Quzhou Hospital Affiliated to Wenzhou Medical UniversityQuzhou324000China National laboratory of Solid State Microstructures College of Engineering and Applied SciencesNanjing UniversityNanjing210093China

Recent experiments have demonstrated that synthesized complex-frequency waves can impart a virtual gain to molecule sensing systems,which can effectively restore information lost due to intrinsic molecular damping.The enhancement notably amplifies the signal of trace molecular vibrational fingerprints,thereby substantially improving the upper limit of sensitivity.

关键词： thereby Complex limit