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A Method for Evaluating the Maximum Bending Degree of Flexural Toppling Rock Masses Based on the Rock Tensile Strain-Softening Model

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Journal of Earth Science 2024年第4期35卷 1243-1253页

作者： Jiongchao Wang Jun Zheng Jichao Guo Qing lü Jianhui Deng Department of Civil Engineering Zhejiang UniversityHangzhou310058China Center for Balance Architecture Zhejiang UniversityHangzhou310007China State Key laboratory of Hydraulics and Mountain River Engineering College of Water Resource and HydropowerSichuan UniversityChengdu610065China

Flexural toppling occurs when a series of layered rock masses bend towards their free *** is important to evaluate the maximum bending degree and the requirement of supports of flexural toppling rock mass to prevent rock mass cracking and even failure leading to a *** on the rock tensile strain-softening model,this study proposes a method for calculating the maximum curvature(C_(ppmax))of flexural toppling rock *** applying this method to calculate Cppmax of 9 types of rock masses with different hardness and rock layer thickness,some conclusions are drawn:(1)the internal key factors affecting C_(ppmax)are E^(⋆)(E^(⋆)=E_(ss)/E_(0),where E_(0)and E_(ss)are the mean deformation moduli of the rock before and after reaching its peak tensile strength,respectively),the strainεt corresponding to the tensile strength of rock,and the thickness(h)of rock layers;(2)hard rock layers are more likely to develop into block toppling than soft rock layers;and(3)thin rock layers are more likely to remain in flexural toppling state than thick rock *** addition,it is found that C_(ppmax)for flexural toppling rock masses composed of bedded rocks such as gneiss is related to the tensile direction.

关键词： flexural toppling rock mass maximum bending degree strain-softening model curvature rock mechanics

Proteomic response of Phaeocystis globosa to nitrogen limitation

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Journal of Oceanology and limnology 2024年第1期42卷 141-149页

作者： Haisu lIU Ruiwang WEI Qiangyong lEI lei CUI Songhui lÜ Key laboratory of Eutrophication and Red Tide Prevention Research Center for Harmful Algae and Marine BiologyJinan UniversityGuangzhou 510632China Southern Marine Science and Engineering Guangdong laboratory Zhuhai 519082China National Engineering laboratory of Electronic and Information Standardization Shenzhen 518057China

Phaeocystis globosa is an important unicellular eukaryotic alga that can also form *** can cause massive harmful algal blooms and plays an important role in the global carbon or sulfur *** far,the ecophysiology of *** has been investigated by numerous ***,the proteomic response of *** to nitrogen depletion remains largely *** compared four protein preparation methods of *** for two-dimensional electrophoresis(2-DE)(Urea/Triton X-100 with trichloroacetic acid(TCA)/acetone precipitation;TCA/acetone precipitation;Radio Immuno Precipitation Assay(RIPA)with TCA/acetone precipitation;and Tris buffer).Results show that the combination of RIPA with TCA/acetone precipitation had a clear gel background and showed the best protein spot separation effect,based on which the proteomic response to nitrogen depletion was studied using *** addition,we identified six differentially expressed proteins whose relative abundance increased or decreased more than 1.5-fold(Pld not be identified,which might be attributed to the lack of genomic sequences of *** nitrogen limitation,replication protein-like,RNA ligase,and sn-glycerol-3-phosphate dehydrogenase were reduced,which may decrease the DNA replication level and ATP production in *** *** increase of endonucleaseⅢand transcriptional regulator enzyme may affect the metabolic and antioxidant function of *** cells and induce cell *** findings provide a basis for further proteomic study of *** and the optimization of protein preparation methods of marine microalgae.

关键词： Phaeocystis globosa nitrogen limitation proteomic response two-dimensional electrophoresis

Black hole shadows in Einstein-Bel-Robinson gravity

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Chinese Physics C 2024年第5期48卷 272-283页

作者： B.Hamil B.C.lütfüoğlu laboratoire de Physique Mathématique et Subatomique Facultédes Sciences ExactesUniversitéConstantine 1ConstantineAlgeria Department of Physics University of Hradec KrálovéRokitanského 6250003 Hradec KrálovéCzechia

Gravity models given by higher-order scalar curvature corrections are believed to bear important consequences. Einstein-Bel-Robinson (EBR) gravity with quartic curvature modification motivated Sajadi et al. to explore static spherically symmetric black hole solutions using perturbative methods. In this study, inspired by their work, we investigate AdS black hole shadows in EBR gravity and demonstrate how the gravity parameter alters the energy emission rate. Finally, we address the same problem in the presence of plasma, because the black holes are thought to be surrounded by a medium that changes the geodesic of photons.

关键词： black hole shadows Einstein-Bel-Robinson gravity plasma

A review of whole-medical systems and holistic care approach for type 2 diabetes and associated metabolic syndrome

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Journal of Integrative Medicine 2024年第3期22卷 199-209页

作者： loveness Makoni Idah T.Manduna Alaisa l.Mbiriri Department of Health Sciences Faculty of Health and Environmental Health SciencesCentral University of TechnologyFree State20 President Brand StreetPrivate bag X20539Bloemfontein 9300South Africa Centre for Applied Food Sustainability and Biotechnology(CAFSaB) Faculty of Health and Environmental Health SciencesCentral University of TechnologyFree State20 President Brand StreetPrivate bag X20539Bloemfontein 9300South Africa Adventist Development and Relief Agency(ADRA) 5 Cecil RoadGreendaleHarare 0000Zimbabwe

Whole-person care and holistic care approach has been proposed for complementary and integrative health care for type 2 diabetes ***,some doubts still exist on the feasibility of replicating processes followed in clinical trials and observational studies in real-world *** narrative literature review summarized and assessed existing clinical evidence(clinical trials,observational studies,and case reports)describing holistic and integrated care approach in adult and adolescent individuals with type 2 diabetes mellitus in clinical *** goal was to highlight existing evidence for implementation and outcomes of whole-medical systems and holistic integrated care approach for type 2 diabetes mellitus.A nonsystematic literature search was performed on Google Scholar,PubMed,Web of Science,ProQuest and ScienceDirect to identify clinical evidence from different parts of the world,evaluating the use of whole-medical systems and/or holistic care interventions in clinical practice for management of type 2 diabetes *** keywords were used in the *** were analyzed using content analysis and simple descriptive statistics(percentages).Most of the studies(64%)were mainly conducted in Eastern countries(India,China and Israel)while 36%of the studies were conducted in the Western countries(USA,Netherlands,Canada and Mexico).lifestyle medicine and integrated naturopathy were shown to be the commonly used whole-medical systems for type 2 diabetes mellitus *** improvements in type 2 diabetes parameters,medication use,other symptoms,and overall feeling of wellness were observed in all *** review study revealed limited utilization and/or documentation of whole-medical systems or holistic care treatments for type 2 diabetes mellitus in regions of the world other than eastern *** medicine,naturopathy,yoga,Ayurveda and traditional Chinese medicine were shown to be effective for type 2 diabetes mellitu

关键词： Complementary and alternative medicine Holistic care Integrative medicine Type 2 diabetes mellitus Team-based intervention

Mogroside IIE,an in vivo metabolite of sweet agent,alleviates acute lung injury via Pla2g2a-EGFR inhibition

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Food Science and Human Wellness 2024年第1期13卷 299-312页

作者： Weichao lü Guoqing Ren Kuniyoshi Shimizu Renshi li Chaofeng Zhang State Key laboratory of Natural Medicines School of Traditional Chinese PharmacyChina Pharmaceutical UniversityNanjing 211198China Sino-Jan Joint lab of Natural Health Products Research School of Traditional Chinese PharmacyChina Pharmaceutical UniversityNanjing 211198China Faculty of Agriculture Kyushu UniversityFukuoka 819-0395Japan

In the face of increasingly serious environmental pollution,the health of human lung tissues is also facing serious *** IIE(M2E)is the main metabolite of sweetening agents mogrosides from the anti-tussive Chinese herbal Siraitia *** study elucidated the anti-inflammatory action and molecular mechanism of M2E against acute lung injury(AlI).A lipopolysaccharide(lPS)-induced AlI model was established in mice and MH-S cells were employed to explore the protective mechanism of M2E through the western blotting,co-immunoprecipitation,and quantitative real time-PCR *** results indicated that M2E alleviated lPS-induced lung injury through restraining the activation of secreted phospholipase A2 type IIA(Pla2g2a)-epidermal growth factor receptor(EGFR).The interaction of Pla2g2a and EGFR was identified by *** addition,M2E protected AlI induced with lPS against inflammatory and damage which were significantly dependent upon the downregulation of AKT and m TOR via the inhibition of ***2g2a may represent a potential target for M2E in the improvement of lPS-induced lung injury,which may represent a promising strategy to treat AlI.

关键词： Mogroside IIE Acute lung injury Secreted phospholipase A2 type IIA(Pla2g2a) Epidermal growth factor receptor(EGFR)

Application of Gaussian Beam Summation Migration in Reflected In-seam Wave Imaging

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Acta Geologica Sinica(English Edition) 2024年第1期98卷 276-284页

作者： HAN Jianguang lÜQingtian ZHANG Zhiheng YANG Shun WANG Shuo Chinese Academy of Geological Sciences Beijing 100037China Shandong Taishan Resources Exploration Co. Ltd.Jinan 250104China

The geological conditions for coal mining in China are complex,with various structural issues such as faults and collapsed columns seriously compromising the safety of coal mine ***-seam wave exploration is an effective technique for acquiring detailed information on geological structures in coal seam working ***,the existing reflected in-seam wave imaging technique can no longer meet the exploration precision requirements,making it imperative to develop a new reflected in-seam wave imaging *** study applies the Gaussian beam summation(GBS)migration method to imaging coal seams'reflected in-seam wave ***,with regard to the characteristics of the reflected in-seam wave data,methods such as wavefield removal and enveloped superposition are employed for the corresponding wavefield separation,wave train compression and other processing of reflected in-seam ***,imaging is performed using the GBS migration *** feasibility and effectiveness of the proposed method for reflected in-seam wave imaging are validated by conducting GBS migration tests on 3D coal-seam fault models with different dip angles and *** applying the method to reflected in-seam wave data for an actual coal seam working face,accurate imaging of a fault structure is obtained,thereby validating its practicality.

关键词： reflected in-seam wave Gaussian beam summation migration numerical tests fault

Oligodendroctyes:the forgotten players of diabetes pathophysiology

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Neural Regeneration Research 2024年第11期19卷 2349-2350页

作者： Juan Antonio lópez-Villodres Beatriz García-Díaz Departamento Fisiología Humana Histología HumanaAnatomía Patológica y Educación Física y DeportivaFacultad de MedicinaUniversidad de MálagaMálagaSpain UGC Neurociencia.Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina(IBIMA Plataforma Bionand) MálagaSpain

Oligodendrocytes(Ols),glial cells that provide myelin sheaths to axons in the central nervous system(CNS),have a dual ***,this myelin fatty cover around the axons protects the nerves and is crucial for the saltatory propagation of action *** and not less important,Ols provide trophic support to neurons and ***,Ol metabolism is important for Ol well-being and the proper accomplishment of their functions,and Ol metabolism energetics directly affect the energy metabolism of neighboring neurons.

关键词： metabolism nerves myelin

On an isotropic porous solid cylinder:the analytical solution and sensitivity analysis of the pressure

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Applied Mathematics and Mechanics(English Edition) 2024年第9期45卷 1499-1522页

作者： H.ASGHARI l.MIllER R.PENTA J.MERODIO Departamento de Matematica Aplicada a las TIC ETS de Ingenieria de Sistemas InformaticosUniversidad Politecnica de MadridMadrid 28031Spain School of Mathematics and Statistics University of GlasgowGlasgow G128QQU.K.

Within this work,we perform a sensitivity analysis to determine the influence of the material input parameters on the pressure in an isotropic porous solid *** provide a step-by-step guide to obtain the analytical solution for a porous isotropic elastic cylinder in terms of the pressure,stresses,and elastic *** obtain the solution by performing a laplace transform on the governing equations,which are those of Biot's poroelasticity in cylindrical polar *** enforce radial boundary conditions and obtain the solution in the laplace transformed domain before reverting back to the time *** sensitivity analysis is then carried out,considering only the derived pressure *** analysis finds that the time t,Biot's modulus M,and Poisson's ratio ν have the highest influence on the pressure whereas the initial value of pressure P_(0) plays a very little role.

关键词： sensitivity analysis laplace transform cylindrical polar coordinate Biot's modulus cylinder

Material flow analysis and global warming potential assessment of an industrial insect-based bioconversion plant using housefly larvae

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Journal of Environmental Sciences 2024年第5期139卷 483-495页

作者： Tao lu Fan lü Nanlin liao Honghui Chai Hua Zhang Pinjing He Institute of Waste Treatment and Reclamation Tongji UniversityShanghai 200092China State Key laboratory of Pollution Control and Source Reuse Tongji UniversityShanghai 200092China Zhejiang Qihe Ecological Technology Co. Ltd.Hangzhou 310052China

The significant increase in the demand for biomass waste treatment after garbage classification has led to housefly larvae treatment becoming an attractive treatment *** can provide a source of protein while treating biomass waste,which means that nutrients can be returned to the natural food ***,the performance of this technology in terms of its environmental impacts is still unclear,particularly with regards to global warming potential(GWP).This study used a life cycle assessment(lCA)approach to assess a housefly larvae treatment plant with a treatment capacity of 50 tons of biomass waste per *** lCA results showed that the 95% confidence intervals for the GWP in summer and winter were determined to be 24.46-32.81 kg CO_(2) equivalent(CO_(2)-eq)/ton biomass waste and5.37-10.08 kg CO_(2)-eq/ton biomass waste,*** greater GWP value in summer is due to the longer ventilation time and higher ventilation intensity in summer,which consumes more *** main GWP contributions are from(1)electricity needs(accounting for 78.6% of emissions in summer and 70.2%in winter)and(2)product substitution by mature housefly larvae and compost(both summer and winter accounting for 96.8% of carbon reduction).

关键词： Biomass waste Musca domestica Housefly larvae life cycle assessment Global warming potential