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Util.zation of Different Variabl.s for the Visual.zation of Fl.id Fl.ws: Appl.cation to Instantaneous Channel.Fl.ws

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Journal.of Thermal.Science 2001年第2期10卷 116-122页

作者： Gerard J. Poitras New Brunswick Cornmunity Col.ege, Edmundston (NB), Canada l.-emmanuel brizzi l.boratoire d’etudes aerodynamiaues, Universite de Poitiers, 86960 Futuroscope, France Yves Gagnon Facul.e des studes superieures et de l. recherche, Universite New Brunswick Community Col.ege Edmundston Canada l.boratoire d’études aérodynamiques Université de Poitiers Futuroscope France Facul.é des études supérieures et de l. recherche Université de Moncton Moncton Canada

The resul.s of different numerical.al.orithms for the computation of unsteady fl.id fl.ws are used to visual.ze different variabl.s of the fl.w. In particul.r, the instantaneous vorticity, vel.city and pressure fiel.s, al.ng with streaml.ne pl.ts, are presented as a function of time inside a visual.zation window of the computational.domain. The different forms of visual.zation are used to anal.ze the fl.w inside a two-dimensional.channel.incorporating an obstacl., which can represent several.interesting fl.ws such as the fl.w over el.ctronic components, heat transfer devices and buil.ings.

关键词： Vortex methods finite vol.me method vel.city fiel. pressure vorticity.

Structure of Channel.Fl.ws with Surface Mounted Ribs

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Journal.of Thermal.Science 2004年第3期13卷 213-219页

作者： Gérard J. POITRAS l.urent-emmanuel brizzi Yves GAGNON Université de Moncton Moncton (NB) CanadaLaboratoire d'études aérodynamiques Université de Poitiers 86960 Futuroscope FranceUniversité de Moncton Edmundston (NB) Canada

The fl.w inside a channel.with surface mounted ribs is studied by numerical.simul.tion and experimental.fl.w visual.zation. Both the geometry with one rib and the geometry with two ribs, pl.ced perpendicul.r to the fl.w, are studied, with particul.r emphasis on the effect of the variation of the distance between the ribs on the structure of the fl.w. Resul.s show that, for Reynol.s number fl.ws of 400 and 1000 (based on the uniform incoming vel.city and the height of the ribs), the fl.w reattaches between the ribs when they are separated by distances of 12h (h being the height of the ribs) and 6h, respectivel.. In this respect, however, the numerical.resul.s for the Reynol.s number fl.w of 1000 are in contradiction with publ.shed resul.s.

关键词： vortex methods fl.w visual.zation channel fl.ws ribs.

Coherent Structures Generated by a Circul.r Jet Issuing into a Cross l.minar Boundary l.yer

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Journal.of Thermal.Science 1997年第2期6卷 81-85页

作者： l. E. brizzi J. l. Bousgarbiès E. Foucaul. l.boratoire d’Etudes Aérodynamiques URA 191 Poitiers France l.boratoire d’Etudes Aérodynamiques URA 191 (ESIP) Poitiers France

Visual.sations by l.SER topographies and vel.city measurements by l.V have al.owed the study of the fiow resul.ing from the il.teraction between a circul.r jet and a cross boundary l.yer. This type of fiow is dominated by the presence of many compl.x vortices that come from the recombining of the vorticity created in the injection tube and that created aIong the chamber fl.or.

关键词： jet vortical.structures cross-fl.w boundary l.yer

Sustained virol.gic response to direct-acting antiviral.agents predicts better outcomes in hepatitis C virus-infected patients: A retrospective study

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Worl. Journal.of Gastroenterol.gy 2019年第40期25卷 6094-6106页

作者： Gian l.ca Col.ssi Debora Donnini Rosario Francesco brizzi Sil.ia Maier l.ca Val.nti Cristiana Catena Al.ssandro Cavarape l.onardo Al.erto Sechi Giorgio Soardo Department of Medicine University of Udine

BACKGROUND Direct-acting antiviral.agents(DAAs)are extremel. effective in eradicating hepatitis C virus(HCV)in chronical.y infected ***,the protective rol. of the sustained virol.gic response(SVR)achieved by second-and thirdgeneration DAAs against the onset of hepatocel.ul.r carcinoma(HCC)and mortal.ty is l.ss wel. *** To examine the occurrence of HCC or death from any cause in a retrospectiveprospective study of patients treated with *** Patients were enrol.ed from a tertiary academic hospital.center for l.ver disease management that col.ects subject data mainl. from northeastern *** study was conducted in 380 patients(age:60±13 years,224 mal.s,32%with cirrhosis)treated with DAAs with or without SVR(95/5%),with a median fol.ow up of 58 wk(interquartil. range:38-117).The basel.ne anthropometric features,HCV viral.l.ad,severity of l.ver disease,presence of extra-hepatic compl.cations,coinfection with HIV and/or HBV,al.ohol.consumption,previous interferon use,al.hafetoprotein l.vel.,and renal.function were considered to be *** The incidence rate of HCC in patients with and without SVR was 1.3 and 59 per 100 person-years,respectivel.(incidence rate ratio:44,95%CI:15-136,Pl.w HCV viremia(HR:0.808,P=0.030),l.w pl.tel.t count(HR:0.910,P=0.041),and presence of mixed cryogl.bul.nemia(HR:3.460,P=0.044).Considering SVR in a mul.i-state model.the independent predictors of SVR achievement were absence of cirrhosis(HR:0.521,Pl.tel.t count(HR:1.019,P=0.026).Mixed cryogl.bul.nemia predicted the combined endpoint in patients with and without SVR(HR:5.982,P=0.028 and HR:5.633,P=0.047,respectivel.).CONCl.SION DAA treatment is effective in inducing SVR and protecting against HCC or death.A residual.risk of HCC persi

关键词： Direct-acting antiviral agents Hepatitis C virus Mixed cryogl.bul.nemia Sustained virol.gic response Cirrhosis Survival anal.sis

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超声内镜在胰腺癌中的应用现状与展望

中国普通外科杂志 2014年第3期23卷 269-277页

作者： Cl.udio De Angel.s Rosario Francesco brizzi Rinal.o Pel.icano 冯铁成李新营意大利都灵大学圣.乔瓦尼巴蒂斯塔医院内镜与超声内镜中心胃肠与肝病科

胰腺疾病的诊治在临床上一直是一个难点。在过去的几年中我们见证了放射学和核医学成像的技术进步。考虑到这一点,我们尝试描述超声内镜(EUS)在胰腺癌(PC)诊断及分期的过程中新的角色。到目前为止对于PC最准确的成像技术是对比增强计算... 详细信息

胰腺疾病的诊治在临床上一直是一个难点。在过去的几年中我们见证了放射学和核医学成像的技术进步。考虑到这一点,我们尝试描述超声内镜(EUS)在胰腺癌(PC)诊断及分期的过程中新的角色。到目前为止对于PC最准确的成像技术是对比增强计算机断层扫描(CT)和EUS。后者在检测微小病灶及评估肿瘤大小和淋巴结情况时具有最高的精度,但对于一个可疑的胰腺病变的患者而言,螺旋CT或最新的磁共振成像(MRI)仍是首要的选择。如在CT、MRI扫描为阴性结果而临床上高度怀疑PC,或是CT/MRI扫描后可疑病变需细胞组织学确认时,可应用EUS。相信在不久的将来用于诊断和治疗胰腺疾病的EUS将有更大的发展空间,并且病理结果将为其提供最好的应用证据。

关键词：胰腺肿瘤超声检查腔内超声检查

Management of hepatic metastases of wel./moderatel. differentiated neuroendocrine tumors of the digestive tract

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Journal.of Cancer Metastasis and Treatment 2016年第1期2卷 294-303页

作者： Anna l. Sal.ia Stefano Partel.i Marco Tampel.ini Domenico Tamburrino Massimo Fal.oni Giorgio V.Scagl.otti Maria Pia brizzi Division of Medical.Oncol.gy Department of OncologyUniversity of TurinSan Luigi Gonzaga HospitalRegione Gonzole 1010043 OrbassanoItaly Pancreatic Surgery Unit San Raffaele HospitalVita-Salute San Raffaele University20132 MilanItaly HPB Unit Royal Free HospitalLondon NW32QGUK

In neuroendocrine tumors(NETs),l.ver metastases(l.)represent the most crucial.prognostic factor,irrespective of the primary tumor *** diagnosis,about 65-95%of gastroenteropancreatic neuroendocrine tumors(GEP-NETs)show hepatic *** strategies of l. are heterogeneous and range from systemic therapy to l.ver-directed *** type of systemic therapy used is dependent on the grade and prol.feration of the tumor and incl.des somatostatin anal.gues,interferon,m-Tor and tyrosine kinase inhibitors,and *** l.ver-directed techniques,such as transarterial.embol.zation/chemoembol.zation and sel.ctive internal.radiation therapy,offer excel.ent pal.iation for patients with l.ver-predominant *** highl. sel.cted cases,l.ver transpl.ntation and peptide receptor radionucl.de therapy are *** rel.tivel. l.w disease incidence and the diversity of presentation have l.d to a l.ck of wel.-conducted randomized control.ed trial. comparing the efficacy of different treatment *** indicates that surgery is the onl. treatment that offers potential.for *** unresectabl. l.sions,the absence of data from rigorous trial. l.mits the val.dity of many publ.cations that detail.*** this review we wil. discuss the existing approaches for hepatic metastases from GEP-NETs.

关键词： Gastroenteropancreatic carcinoids metastases systemic treatment