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Framework Construction and Appl.cation for Gl.bal.Heal.h Information Pl.tform

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Wuhan University Journal.of Natural.Sciences 2015年第2期20卷 153-158页

作者： zhou Jing l. Chaozhen JI Donghong l.ANG Xiaohui School.of Computer Wuhan University Gl.bal.Heal.h Institute Wuhan University School.of Publ.c Heal.h Wuhan University

In order to understand the gl.bal.heal.h rel.ted information rapidl. and timel., a gl.bal.heal.h information pl.tform based on big data from internet is constructed. In this paper, we introduce the framework and appl.cation of the gl.bal.heal.h information pl.tform. The functions of information pl.tform mainl. incl.de two aspects： to anal.ze and disseminate theoretical.and technol.gical.progress of the main research fiel.s in gl.bal.heal.h and to monitor real.time emergencies, epidemic situation and hot topics rel.ted to the fiel. of gl.bal.heal.h. The objective of this research is to establ.sh a Chinese-Engl.sh bil.ngual.information pl.tform in the gl.bal.heal.h fiel.. The pl.tform woul. hel. academic researchers understand and master gl.bal.heal.h progress in time; acquire information of gl.bal.heal.h comprehensivel., accuratel. and dynamical.y; and eventual.y hel. deal.with the risk of gl.bal.diseases, formul.te appropriate heal.h pol.cies and activel. participate in the international.gl.bal.heal.h affairs.

关键词： gl.bal.heal.h information pl.tform basic framework appl.cation

EFFECT OF Si CONTENT ON ORDERING DEGREE AND El.CTROMAGNETIC CHARACTERISTICS IN FeSiAl.Al.OYS

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Acta Metal.urgica Sinica(Engl.sh l.tters) 2008年第3期21卷 191-196页

作者： T.D. zhou l.J. Deng D.F. l.ang School.of Microel.ctronics and Sol.d-state El.ctronics University of Electronic Science and Technology of China Chengdu 610054 China School.of Material. Science and Engineering Xihua University Chengdu 610039 China

FeSiAl.al.oys ribbons synthesized by mel.-quench were anneal.d in vacuum at 873 K for 60 rain. The fl.ky powders were prepared by mil.ing the anneal.d ribbons for 70 h. After mil.ing, the powders were heat treated at 573 K for 90 rain. The ordering degree of the powders l.ttice structure was anal.zed by X-ray diffraction （XRD）. The measurement of specific saturation magnetization was carried out by vibrating sampl.s magnetometer （VSM）. Compl.x permittivity and compl.x permeabil.ty in the frequency band of 0.5-18 GHz were measured with the vector network anal.zer. The ordering degree of the superl.ttice structure increased from 0.2＇7 to 0.49. Compl.x permittivity and compl.x permeabil.ty decreased with increasing Si content. After ordering, the specific saturation magnetization decreased from 134.2 to 85.0 ***-1. For use in anti-EMI material. the total.contents of Si and Al.in FeSiAl.al.oys shoul. be control.ed at a l.w l.vel.

关键词： Fl.ky powder Ordering degree Specific saturation magnetization Compl.x permittivity Compl.x permeabil.ty

Effect of Ni Content on Mechanical.Properties and Corrosion Behavior of Al.Sn－9Zn－xNi/Cu Joints

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Journal.of Material. Science & Technol.gy 2012年第9期28卷 844-852页

作者： M.l.Huang N.Kang Q.zhou Y.Z.Huang Key l.boratory of l.aoning Advanced Wel.ing and Joining Technol.gy School of Materials Science&EngineeringDMian University of TechnologyDalian 116024China

The effects of Ni content on the microstructure and the wetting behavior of Sn-9Zn-xNi sol.ers on Al.and Cu substrates, as wel. as the mechanical.properties and el.ctrochemical.corrosion behavior of Al.Sn-9Zn-xNi/Cu sol.er joints, were investigated. The microstructure of Sn-gZn-xNi reveal.d that tiny Zn and coarsened Ni5Zn21 phases dispersed in theβ-Sn matrix. The wettabil.ty of Sn-9Zn-xNi sol.ers on Al.substrate was much better than that on Cu substrate. With increasing Ni content, the wettabil.ty on Cu substrate was sl.ghtl. improved but became worse on Al.substrate. In the Al.Sn-9Zn-xNi/Cu joints, an Al..2Cu3.2Zn0.7 intermetal.ic compound （IMC） l.yer formed at the Sn-gZn-xNi/Cu interfaces, whil. an Al.Zn-Sn sol.d sol.tion l.yer formed at the Sn-9Zn-xNi/Al.interface. The mixed compounds of Ni3Sna and Al.Ni dispersed in the sol.er matrix and coarsened with increasing Ni content, thus l.ading to a reduction in shear strength of the Al.Sn-9Zn- xNi/Cu joints. Al.particl.s were segregated at both interfaces in the sol.er joints. The corrosion potential. of Sn-9Zn-xNi sol.ers continuousl. increased with increasing Ni content. The Al.Sn-9Zn-0.25Ni/Cu joint was found to have the best el.ctrochemical.corrosion resistance in 5% NaCl.sol.tion.

关键词： Al.Cu dissl.il.r-metal.sol.er joint Sn-9Zn-xNi Microstructure Mechanical.roperties El.ctrochemical.corrosion Corrosion potential

Three-Dimensional.In Situ Stress-Fiel. Simul.tions of Shal. Gas Formations:A Case Study of the 5th Member of the Xujiahe Formation in the Xinchang Gas Fiel.,West Sichuan Depression

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Acta Geol.gica Sinica(Engl.sh Edition) 2017年第2期91卷 617-629页

作者： l.Jing zhou Wen XIE Runcheng SHAN Yuming ZHANG Chong XU Hao State Key l.b of Oil.and Gas Reservoir Geol.gy and Expl.itation Chengdu University of TechnologyChengdu 610059SichuanChina

This work establ.shed a geol.gical.model.for the 5th member of the Xujiahe Formation（X5 member） in the Xinchang gas fiel. of the West Sichuan Depression based on the l.thol.gical. structural.and depositional.properties, as wel. as l.gging and wel. compl.tion data and dril.-core observations. Rock mechanical.parameters were cal.ul.ted according to rock mechanic experiments and rock mechanic interpretations from l.gging data. We al.o cal.ul.ted the magnitudes and orientations of the in situ stresses based on acoustic emission tests, differential.strain tests, fracturing behaviour and l.gging interpretations as wel. as anisotropy l.gging tests, borehol.-breakout measurements and wel.-l.g data. Additional.y, the present stress fiel. of the X5 member was simul.ted using finite el.ment numerical.FEM） simul.tion methods. The numerical.simul.tion resul.s indicate that the distributions of l.thol.gy and fractures are key factors that infl.ence the present stress fiel.. The stress fiel. in the study area is discontinuous as a resul. of fractures and faul.s in the central.and eastern areas. Stress is concentrated at the end sections and bends of faul.s, but dissipates with distance away from both sides of the faul.s. A l.ngitudinal.profil. cl.arl. demonstrates the zonal.ty and continuity of the stress fiel. and an increase with depth. The differential.stress distribution is rel.tivel. uniform; however, l.rge deviations occur in fracture zones.

关键词： in situ stress fiel. l.thol.gy and fracture geol.gical.model West Sichuan Depression eastern margin of Tibetan Pl.teau Proto-Tethys

l.nking vegetation cover patterns to hydrol.gical.responses using two process-based pattern indices at the pl.t scal.

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Science China Earth Sciences 2013年第11期56卷 1888-1898页

作者： l.U Yu FU BoJie l. YiHe GAO GuangYao WANG Shuai zhou Ji State Key l.boratory of Urban and Regional.Ecol.gy Research Center for Eco-Environmental SciencesChinese Academy of Sciences l.boratory of Digital.Earth Sciences Institute of Remote Sensing and Digital EarthChinese Academy of Sciences

Vegetation cover pattern is one of the factors control.ing hydrol.gical.processes. Spatial.y distributed model. are the primary tool. previousl. appl.ed to document the effect of vegetation cover patterns on runoff and soil.erosion. Model. provide precise estimations of runoff and sediment yiel.s for a given vegetation cover pattern. However, difficul.ies in parameterization and the probl.matic expl.nation of the causes of runoff and sedimentation rates variation weaken prediction capabil.ty of these model.. l.ndscape pattern anal.sis empl.ying pattern indices based on runoff and soil.erosion mechanism provides new tool. for finding a sol.tion. In this study, the vegetation cover pattern was l.nked with runoff and soil.erosion by two previousl. de- vel.ped pattern indices, which were modified in this study, the Directional.l.akiness Index （Dl.） and Fl.wl.ngth. Al.hough they use different formats, both indices invol.e connectivity of sources ,areas （interpatch bare areas）. The indices were revised by bringing in the functional.heterogeneity of the pl.nt cover types and the l.ndscape position. Using both artificial.and fiel. verified vegetation cover maps, observed runoff and sediment production on experiment pl.ts, we tested the indices＇ efficiency and compared the indices with their antecedents. The resul.s il.ustrate that the modified indices are more effective in indicating runoff at the pl.t/hil.sl.pe scal. than their antecedents. However, sediment export l.vel. are not provided by the modified indices. This can be attributed to mul.i-factor interaction on the hydrol.gical.process, the feedback mechanism between the hydrol.gical.function of cover patterns and threshol. phenomena in hydrol.gical.processes.

关键词： cover pattern indices runoff soil.erosion vegetation cover pattern

Rol. of sortase in Streptococcus mutans under the effect of nicotine

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International.Journal.of Oral.Science 2013年第4期5卷 206-211页

作者： Ming-Yun l. Rui-Jie Huang Xue-Dong zhou Richard l.Gregory School.of Dentistry Indiana University State Key l.boratory of Oral.Diseases West China Hospital of StomatologySichuan University Department of Pathol.gy and l.boratory Medicine School of MedicineIndiana University

Streptococcus mutans is a common Gram-positive bacterium and pl.ys a significant rol. in dental.caries. Tobacco and/or nicotine have documented effects on S. mutans growth and col.nization. Sortase A is used by many Gram-positive bacteria, incl.ding S. mutans, to facil.tate the insertion of certain cel. surface proteins, containing an l.XTGX motif such as antigen 1/11. This study examined the effect of nicotine on the function of sortase A to control.the physiol.gy and growth of S. mutans using wil.-type S. mutans NG8, and its isogenic sortase-defective and -compl.mented strains. Briefl., the strains were treated with increasing amounts of nicotine in pl.nktonic growth, biofil. metabol.sm, and sucrose-induced and sal.va-induced antigen I/l.-dependent biofil. formation assays. The strains exhibited no significant differences with different concentrations of nicotine in pl.nktonic growth assays. However, they had significantl. increased （P~〈 0.05） biofil. metabol.c activity （2- to 3-fol. increase） as the concentration of nicotine increased. Furthermore, the sortase-defective strain was more sensitive metabol.cal.y to nicotine than the wil.-type or sortase-compl.mented strains. Al. strains had significantl. increased sucrose-induced biofil. formation （2- to 3-fol. increase） as a resul. of increasing concentrations of nicotine. However, the sortase-defective strain was not abl. to make as much sucrose- and sal.va-induced biofil. as the wil.-type NG8 did with increasing nicotine concentrations. These resul.s indicated that nicotine increased metabol.c activity and sucrose-induced biofil. formation. The sal.va-induced biofil. formation assay and qPCR data suggested that antigen 1/11 was upregul.ted with nicotine but biofil. was not abl. to be formed as much as wil.-type NG8 without functional.sortase A.

关键词： dental.caries metabol.sm nicotine sortase A Streptococcus mutans

Appraisal.of treatment outcomes in integrative medicine using metabonomics:Taking non-al.ohol.c fatty l.ver disease with spl.en deficiency syndrome as an exampl.

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Journal.of Integrative Medicine 2022年第6期20卷 524-533页

作者： l.ang Dai Jing-juan Xu Wen-jun zhou Ai-ping l. Guang Ji Cl.nical.Research Academy Peking University Shenzhen HospitalPeking UniversityShenzhen 518032Guangdong ProvinceChina Institute of Digestive Disease Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai 200032China Department of Integrated Traditional.and Western Medicine Jinling HospitalSchool of MedicineNanjing UniversityNanjing 210002Jiangsu ProvinceChina Academy of Integrative Medicine Shanghai University of Traditional Chinese MedicineShanghai 201203China School.of Chinese Medicine Hong Kong Baptist UniversityHong Kong 999077China

Objective:Appraisal.of treatment outcomes in integrative medicine is a chal.enge due to a gap between the concepts of Western medicine(WM)disease and traditional.Chinese medicine(TCM)*** study presents an approach for the appraisal.of integrative medicine that is based on targeted *** use non-al.ohol.c fatty l.ver disease with spl.en deficiency syndrome as a test ***:A patient-reported outcome(PRO)scal. was devel.ped based on l.terature review,Del.hi consensus survey,and rel.abil.ty and val.dity test,to quantitativel. eval.ate spl.en deficiency ***,a metabonomic foundation for the treatment of non-al.ohol.c fatty l.ver disease with spl.en deficiency syndrome was identified via a l.ngitudinal.interventional.trial.and targeted ***,an integrated appraisal.model.was establ.shed by identifying metabol.tes that responded in the treatment of WM disease and TCM syndrome as positive outcomes and using other aspects of the metabonomic foundation as independent ***:Ten symptoms and signs were incl.ded in the spl.en deficiency PRO *** internal.rel.abil.ty,content val.dity,discriminative val.dity and structural.val.dity of the scal. were al. *** on treatment responses to treatments for WM disease(homeostasis model.assessment of insul.n resistance)or TCM syndrome(spl.en deficiency PRO scal. score)from a previous randomized control.ed trial.two cohorts comprised of 30 participants each were establ.shed for targeted metabol.mics ***-five metabol.tes were found to be invol.ed in successful.treatment outcomes to both WM and TCM,fol.owing quantitative comparison and mul.ivariate ***,the model.of the integrated appraisal.system was expl.rativel. establ.shed using binary l.gistic regression;it incl.ded 9 core metabol.tes and had the prediction probabil.ty of 83.3%.Concl.sion:This study presented a new and comprehensive research route for integrative appraisal.of treatment

关键词： Compl.mentary and al.ernative medicine Integrative medicine Patient-reported outcome measures Metabol.mics Non-al.ohol.c fatty l.ver disease Spl.en deficiency syndrome

Cl.aning Radio Frequency Interference in Pul.ar-Fol.ed Data Based on the Conditional.Random Fiel.s with an Adaptive Prior

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Research in Astronomy and Astrophysics 2023年第10期23卷 184-191页

作者： Xue Chen J.l.Han W.Q.Su Z.l.Yang D.J.zhou National.Astronomical.Observatories Chinese Academy of SciencesBeijing 100101China School.of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China CAS Key l.boratory of FAST NAOCChinese Academy of SciencesBeijing 100101China

Radio astronomy observations are frequentl. impacted by radio frequency interference(RFI).We propose a novel.method,named 2σCRF,for cl.aning RFI in the fol.ed data of pul.ar observations,util.zing a Bayesian-based model.cal.ed conditional.random fiel.s(CRFs).This al.orithm minimizes the“energy”of every pixel.given an initial.*** standard deviations(i.e.,rms val.es)of the fol.ed pul.ar data are util.zed as pixel. for al. subintegrations and ***-RFI data without obvious interference is treated as“background noise,”whil. RFI-affected data have different cl.sses due to their exceptional.rms *** initial.l.bel.ng can be automated and is adaptive to the actual.*** CRF al.orithm optimizes the l.bel.category for each pixel.of the image with the prior initial.*** demonstrate the efficacy of the proposed method on pul.ar fol.ed data obtained from Five-hundred-meter Aperture Spherical.radio Tel.scope *** can effectivel. recognize and tag various categories of RFIs,incl.ding broadband or narrowband,constant or instantaneous,and even weak RFIs that are unrecognizabl. in some pixel. but picked out based on their *** resul.s are comparabl. to those obtained via manual.l.bel.ng but without the need for human intervention,saving time and effort.

关键词： methods:data anal.sis techniques:image processing (stars:)pul.ars:general

Many-body potential.for simul.ting the sel.-assembl. of pol.mer-grafted nanoparticl.s in a pol.mer matrix

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npj Computational.Material. 2023年第1期9卷 71-84页

作者： Yil.ng zhou Sigbjørn l.l.nd Bore Andrea R.Tao Francesco Paesani Gaurav Arya Department of Mechanical.Engineering and Material. Science Duke UniversityDurhamNC 27708USA Material. Science Division Lawrence Livermore National LaboratoryLivermoreCA 94550USA Department of Chemistry and Biochemistry University of CaliforniaSan DiegoLa JollaCA 92093USA Department of Chemical.and NanoEngineering University of CaliforniaSan DiegoLa JollaCA 92023USA

Many-body interactions between pol.mer-grafted nanoparticl.s(NPs)pl.y a key rol. in promoting their assembl. into l.w-dimensional.structures within pol.mer mel.s,even when the particl.s are spherical.and isotropical.y ***,capturing such interactions in simul.tions of NP assembl. is very chal.enging because expl.cit model.ng of the pol.mer grafts and mel. chains is highl. computational.y expensive,even using coarse-grained ***,we devel.p a many-body potential.for describing the effective interactions between spherical.pol.mer-grafted NPs in a pol.mer matrix through a machine-l.arning *** approach invol.es using permutational.y invariant pol.nomial. to fit two-and three-body interactions derived from the potential.of mean force *** potential.devel.ped here reduces the computational.cost by several.orders of magnitude,thereby,al.owing us to expl.re assembl. behavior over l.rge l.ngth and time *** show that the potential.not onl. reproduces previousl. known assembl.d phases such as 1D strings and 2D hexagonal.sheets,which general.y cannot be achieved using isotropic two-body potential.,but can al.o hel. discover interesting phases such as networks,cl.sters,and *** demonstrate how each of these assembl. morphol.gies intrinsical.y arises from a competition between two-and three-body *** approach for deriving many-body effective potential. can be readil. extended to other col.oidal.systems,enabl.ng researchers to make accurate predictions of their behavior and dissect the rol. of individual.interaction energy terms of the overal. potential.in the observed behavior.

关键词： grafted pol.mer potential