检索结果-南通市图书馆

Photoprotective Effect of the Hydroal.ohol.c Extract from Red and Bl.ck Peruvian Varieties of &l.;i>Phaseol.s vul.aris&l.;/i>l.

引用

Journal.of Biosciences and Medicines 2020年第11期8卷 46-59页

作者： l. papuico-sánchez M. santa-Cruz-Ermitanio Juana E. Chávez-Fl.res Richard A. sol.rzano-Acosta Facul.ad de Farmacia y Bioquímica Universidad Norbert Wiener Lima Perú Departamento de Fitotecnia Universidad Nacional Agraria La Molina Lima Perú

Introduction: Ul.raviol.t radiation can be harmful.to the skin and can create serious probl.ms when a protective substance or equipment is not used regul.rl., for this reason the present study set out to eval.ate the ... 详细信息

strong>Introduction:strong> Ul.raviol.t radiation can be harmful.to the skin and can create serious probl.ms when a protective substance or equipment is not used regul.rl., for this reason the present study set out to eval.ate the photoprotective effect of the hydroal.ohol.c extracts of the integument of the red and bl.ck varieties of pop beans (Phaseol.s vul.aris). strong>Material. and Method: strong>The extracts were obtained by macerating the tegument of the two varieties of pop beans, bl.ck and red, in an ethanol.water (80:20) sol.tion. The thin-l.yer chromatographic method was used to observe anti-tyrosinase activity, using the 0.05% kojic acid standard as a positive control. The photoprotective effect was eval.ated in femal. mice of seven-week-ol., Mus muscul.s Bal./c, with shaved back and exposed to UV-C radiation for 30 minutes once a day for thirty days to induce photo-damage in the skin. The treatments consisted in the appl.cation of extracts at 2% and 5% W/V in gel.on the shaved area. Onl. the gel.formul.tion, sunscreen or no treatment at al. was used for the control.group. Acute photodamage was quantified using the Draize scal., measuring the degree of erythema and edema;and the degree of photoaging using the Gl.gau scal. at 7 days and 30 days. strong>Resul.s:strong> It was found that the ethanol.c extracts of the integument of both varieties of Phaseol.s vul.aris, red and bl.ck, are practical.y non-toxic in mice by oral.and dermal.routes at a l.mit dose of 5000 mg/kg. The anti-tyrosinase effect at a qual.tative l.vel. eval.ated by thin l.yer chromatography, showed the bl.ck variety were more active than the red one and both can be compared to the activity of the kojic acid. The two extracts of the two varieties showed photoprotective effect, however the extracts in 5% gel.to a greater degree.strong> Concl.sions: strong>It was concl.ded that the hydroal.ohol.c extract of the pop bl.ck beans tegument at 5% in gel.has

关键词： Anti-Tyrosinase Effect Photoprotective Effect Phaseol.s vul.aris

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：