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laser additive manufacturing of biodegradable Mg-based alloys for biomedical applications: A review

Journal of Magnesium and Alloys 2022年第4期10卷 915-937页

作者： c.l.wu W.J.Xie H.c.Man Department of Industrial and Systems Engineering The Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina

Metallic implants are widely used in internal fixation of bone fracture in surgical *** are mainly used for providing mechanical support and stability during bone reunion,which usually takes a few months to *** implants made of stainless steels,Ti-based alloys and cocrMo alloys have been widely used for orthopedic reconstruction due to their high strength and high corrosion *** metallic implants will remain permanently inside the body after implantation,and a second surgery after bone healing is needed because the long-term presence of implant will lead to various *** implant removal surgery not only incurs expenditure,but also risk and psychological *** a consequence,studies on the development of biodegradable implants,which would degrade and disappear in vivo after bone reunion is completed,have drawn researchers’*** this connection,Mg-based alloys have shown great potentials as promising implant materials mainly due to their low density,inherent biocompatibility,biodegradability and mechanical properties close to those of ***,the high degradation rate of Mg-based implants in vivo is the biggest hurdle to *** from materials selection,a fixation implant is ideally tailor-made in size and shape for an individual case,for best surgical ***,laser additive manufacturing(lAM),with the advent of sophisticated laser systems and software,is an ideal process to solve these *** this paper,we reviewed the progress in lAM of biodegradable Mg-based alloys for biomedical *** effect of powder properties and laser processing parameter on the formability and quality was thoroughly *** microstructure,phase constituents and metallurgical defects formed in the lAMed samples were *** mechanical properties,corrosion resistance,biocompatibility and antibacterial properties of the lAMed samples were summarized and compared with samples fabricated by

关键词： laser additive manufacturing Magnesium alloys Implant Biomedical applications Mechanical properties Biodegradability

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Anisotropic Inter-granular corrosion Behaviors and Microstructures of AlMgSicu Alloy Sheets Made by Thermal–Mechanical Treatments

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Acta Metallurgica Sinica(English letters) 2022年第2期35卷 275-284页

作者： l.M.liu Y.X.lai c.l.wu Z.Zhang J.H.chen center for High-Resolution Electron Microscopy College of Materials Science and EngineeringHunan UniversityChangsha 410082China

This study investigates the microstructure and local corrosion behavior of an Al-Mg-Si-cu alloy,which has been subjected to cold-rolling with different deformation strain ratios(DSRs)and followed by artificial *** corrosion tests show that peak-aged samples with a small DSR(5-10%)are sensitive to inter-granular corrosion(IGc)along both the normal and rolling *** the DSR increases to medium strength(20-40%),IGc sensitivity decreases along both directions and corrosion propagates *** the DSR is 60-80%,IGc sensitivity along the normal direction continues to decrease,but increases along the rolling direction,indicating pronounced corrosion *** characterization reveals the decreased IGc sensitivity is mainly attributed to a reduction in element segregation at high-angle grain boundaries and the kinked and discontinuous grain boundary corrosion *** increased IGc sensitivity along the rolling direction could be related to the significantly flattened grains.

关键词： Al alloys local corrosion Anisotropy Transmission electron microscopy(TEM) Electron backscattering diffraction(EBSD)

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Structures and formation mechanisms of dislocation-induced precipitates in relation to the age-hardening responses of Al-Mg-Si alloys

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Journal of Materials Science & Technology 2020年第6期41卷 127-138页

作者： Y.X.lai W.Fan M.J.Yin c.l.wu J.H.chen center for High-Resolution Electron Microscopy College of Materials Science&EngineeringHunan UniversityChangsha 410082China Electron Microscopy center Shenzhen UniversityShenzhen 518060China

In the slightly deformed Al-Mg-Si alloys,dislocation-induced precipitates are frequently observed,and they usually line up,forming sophisticated precipitation *** atomic-resolution electron microscopy in association with hardness measurements,we systematically investigated these precipitates in relation to the age-hardening responses of the *** study reveals that the majority of dislocation-induced complex precipitates are actually short-range ordered while long-range disordered polycrystalline precipitates and multiphase composite precipitates,including polycrystalline U2 precipitates,B’/U2,B’-2/U2,B’/B’-2/U2 and’/U2 composite *** is suggested that the formation of these complex precipitates is mainly owing to a high nucleation rate and rapid growth of different precipitate phases parallel to the associated dislocation *** dislocation-induced precipitates consume more Mg than Si from the matrix and have a high formation kinetics,they will have different impacts on the matrix precipitation in different types of Al-Mg-Si *** results further demonstrate that for the"normally-β"-hardened"alloy,their formation leads to a coarser precipitate microstructure in the matrix,whereas for the"normally-β’-hardened"alloy,their formation reverses the precipitation pathway in the matrix,resulting in a reduced age-hardening potential of the former alloy and an improved age-hardening potential of the latter alloy.

关键词： Al-Mg-Si alloys Precipitation Dislocation Age-hardening Electron microscopy

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A hidden precipitation scenario of theθ’-phase in Al-cu alloys

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Journal of Materials Science & Technology 2021年第16期75卷 126-138页

作者： l.Zhou c.l.wu P.Xie F.J.Niu W.Q.Ming K.Du J.H.chen center for high-resolution electron microscopy college of materials science and engineeringhunan universitychangshahunan410082china shenyang national laboratory for materials science institute of metal researchchinese academy of sciences.shenyan7.110016china

Al-cu binary alloys are important and interesting industry *** to date,the formation mechanisms of the key strengthening precipitates,namedθ’-phase,in the alloys are still ***,we report that for non-deformed bulk Al-cu alloys theθ’-phase actually has its own direct precursors that can form only at elevated aging temperature(>ca.200℃).These high-temperature precursors have the same plate-like morphology as theθ’-phase precipitates but rather different *** imaging reveals that they have a tetragonal structure with a=0.405 nm and c=1.213 nm,and an average composition of Al_(5-x)cu_(1+x)(0≤xlly coherent with the *** precursor phase may initiate with a composition of Al5 cu and evolve locally towards Al_(4)cu_(2)in composition,eventually leading to a consequent structural transformation into theθ’-phase(Al4 cu2=Al2 cu).There are evidences that because of their genetic links in structure,such a high-temperature precursor may transform to theθ’-phase without having to change their morphology and interface *** study reveals a well-defined and previously hidden precipitation scenario for theθ’-phase to form in Al-cu alloys at an elevated aging temperature.

关键词： Alcu alloy Age-hardening Precipitation Electron microscopy

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Variation of sulfate aerosol concentrations over the western Pacific and their effect on clouds, radiation and precipitation

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Acta Oceanologica Sinica 1993年第4期12卷 521-534页

作者： F.Parungo J.Rosinski M.l.c.wu c.T.Nagamoto Air Resources laboratory NOAA/ERL Boulder CO U.S.ANational Center for Atmospheric Research Boulder CO U.S.AGoddard Space Flight Center NASA Greenbelt MD U.S.AAir Resources Laboratory NOAA/ERL Boulder CO U.S.A

Under bilateral cooperation between the United States of America and the People's Republic of china, a series of research cruises were conducted over the western Pacific Ocean. It was found that a) the non-sea-salt sulfate aerosol particles are the major source of cloud condensation nuclei, b) the population of clouds and the total albedo are proportional to the concentration of condensation nuclei and consequently to the concentration of the non-sea-salt aerosol particles, and c) the amount of rainfall is inversely proportional to the concentration of non-sea-salt sulfate aerosol particles. It seems that anthropogenic sulfate aerosol particles affect the regional planetary albedo and climate and that the contribution from biogenically derived sulfate aerosol particles is of lesser importance.

关键词： data Variation of sulfate aerosol concentrations over the western Pacific and their effect on clouds radiation and precipitation over

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cONTROl OF cANcER PAIN TO ENSURE THE BEST POSSIBlE QUAlITY OF lIFE

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Journal of Traditional chinese Medicine 1992年第4期12卷 243-255页

作者： G Q Yu J X liu P W li J X Qin E X Yu l M liu l c wu M H Shen W S Zhou M M li Guang An Men Hospital China Academy of Traditional Chinese Medicine Beijing.

Yu Guiqing 余桂清(Guang An Men Hospi-tal,china Academy of Traditional chineseMedicine,Beijng 100053)The therapeutic strategy regarding can-cer pain is first to get rid of the causes ofpain with anticancer treatment so... 详细信息

关键词： Radix materia stasis anticancer verity herbal 田螺膏 relieve 黑龙丹大黄度虫丸

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Multiple sclerosis is at a checkpoint: advancing the program

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessica l.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

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Post-encode Multi-dye-doped Silica Nanoparticles by Molecule-selective Photobleaching

Post-encode Multi-dye-doped Silica Nanoparticles by Molecule...

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第三十五届国际光谱会议

作者： c.l.wu Y.B.Zhao~* Department of chemistry and the Key laboratory of Analytical Sciences of the Ministry of Education,college of chemistry and chemical Engineering,Xiamen University,Xiamen 361005,china

Rational design and preparation of multicolor nano-pmbes have recently become an area of rapidly expanding interest due to their potential application in multiplexed bioassays. Dye-doped silica nanoparticles own intense fluorescence signal and highly improved photostability make them ideal fluorescent nano-probes for biological ***,

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安徽黄山黄山松的初步观察

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林业科学 1963年第2期 114-126页

作者：吴中伦中国林业科学研究院林业科学研究所

黄山松的形态黄山松是常绿乔木,高达30米,胸径达80厘米;在无风处树干端直;在郁闭林分内,立木干形通直少枝,干形良好,壮龄木树冠塔形,老树顶部平展。在悬崖峯脊,则因强风吹袭,常偏斜或平截。所谓:“绝巘危崖,尽皆怪松悬结,高者不盈丈,低... 详细信息

黄山松的形态黄山松是常绿乔木,高达30米,胸径达80厘米;在无风处树干端直;在郁闭林分内,立木干形通直少枝,干形良好,壮龄木树冠塔形,老树顶部平展。在悬崖峯脊,则因强风吹袭,常偏斜或平截。所谓:“绝巘危崖,尽皆怪松悬结,高者不盈丈,低仅数寸,平顶短鬣,盘根虬干,愈短愈老,愈老愈奇。”树皮暗棕色,鳞片状剥离。枝刚直,斜出。针叶二枚一束,硬直散立,长度则随立地条件有很大差异;在海拔高的峯顶,受风吹袭处,针叶短而密,长度仅4厘米;在海拔低的避风处则长达15厘米。球果长卵形到卵形,外侧稍稍突出,果鳞开裂后球果呈圆锥状卵形,长及径均为4—6厘米;果柄短,长成时向下扭转,可在树上保存2—4年,10月中下旬成熟,成熟后鳞片开裂,种子飞散。种子椭圆形或长圆形,端

关键词：黄山松初步观察全光天然更新森林更新安徽杜鹃黄山杜鹃云谷寺安徽黄山

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Fluorescent core-shell Silica Nanoparticles as Functionable Precursors:Towards Multicolor and Multifunctional Nanoprobes

Fluorescent Core-shell Silica Nanoparticles as Functionable ...

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第三十五届国际光谱会议

作者： c.l.wu J.Q.Hong X.Q.Guo Y.B.Zhao~* Department of chemistry and the Key laboratory of Analytical Sciences of the Ministry of Education college of chemistry and chemical Engineering Xiamen University Xiamen 361005 china

＜正＞Rational design of functional nanoparticles has attracted a great deal of attention in multiplex bioanalysis and multifunctional ***,we have proposed a post-encoding concept[1]to the design and preparation of encoding fluorescent probes, which makes the preparation process of multicolor fluorescent spheres rather laborsaving

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