检索结果-南通市图书馆

Computer Modeling in Engineering & Sciences 2024年第6期139卷 3467-3493页

作者： yan Wang Siwen li na Wei School of Civil Engineering Zhengzhou UniversityZhengzhou450001China

A novel approach for analyzing coupled vibrations between vehicles and bridges is presented,taking into account spatiotemporal effects and mechanical phenomena resulting fromvehicle *** modeling and solution of bridge vibrations induced by vehicle deceleration are realized using this *** method’s validity and reliability are substantiated through numerical examples.A simply supported beam bridge with a corrugated steel web is taken as an example and the effects of parameters such as the initial vehicle speed,braking acceleration,braking location,and road surface roughness on the mid-span displacement and impact factor of the bridge are *** results show that vehicle braking significantly amplifies mid-span displacement and impact factor responses in comparison to uniform vehicular motion across the ***,the influence of wheelto-bridge friction forces is of particular significance and cannot be *** the vehicle initiates braking near the middle of the span,both the mid-span displacement and impact factor of the bridge exhibit substantial increases,further escalating with higher braking *** favorable road surface conditions,the midspan displacement and the impact factor during vehicle braking may exceed the design values stipulated by *** is important to note that road surface roughness exerts a more pronounced effect on the impact factor of the bridge in comparison to the effects of vehicle braking.

关键词： Corrugated steel web girder bridges simply supported beam bridges vehicle-bridge coupled vibration braking impact factor

A New Encrypted Traffic Identification Model Based on VAE-lSTM-DRN

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第1期78卷 569-588页

作者： Haizhen Wang Jinying yan na Jia College of Computer and Control Engineering Qiqihar UniversityQiqihar161006China Heilongjiang Key laboratory of Big Data Network Security Detection and Analysis Qiqihar UniversityQiqiharChina

Encrypted traffic identification pertains to the precise acquisition and categorization of data from traffic datasets containing imbalanced and obscured *** extraction of encrypted traffic attributes and their subsequent identification presents a formidable *** existing models have predominantly relied on direct extraction of encrypted traffic data from imbalanced datasets,with the dataset’s imbalance significantly affecting the model’s *** the present study,a new model,referred to as UD-VlD(Unbalanced Dataset-VAE-lSTM-DRN),was proposed to address above *** proposed model is an encrypted traffic identification model for handling unbalanced *** encoder of the variational autoencoder(VAE)is combined with the decoder and long-short term Memory(lSTM)in UD-VlD model to realize the data enhancement processing of the original unbalanced *** enhanced data is processed by transforming the deep residual network(DRN)to address neural network gradient-related ***,the data is classified and *** UD-VlD model integrates the related techniques of deep learning into the encrypted traffic recognition technique,thereby solving the processing problem for unbalanced *** UD-VlD model was tested using the publicly available Tor dataset and VPN *** UD-VlD model is evaluated against other comparative models in terms of accuracy,loss rate,precision,recall,F1-score,total time,and ROC *** results reveal that the UD-VlD model exhibits better performance in both binary and multi classification,being higher than other encrypted traffic recognition models that exist for unbalanced ***,the evaluation performance indicates that the UD-VlD model effectivelymitigates the impact of unbalanced data on traffic *** can serve as a novel solution for encrypted traffic identification.

关键词： Data enhancement lSTM deep residual network VAE

Insights into seasonal variation of litter decomposition and related soil degradative enzyme activities in subtropical forest in China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Forestry Research 2013年第4期24卷 683-689页

作者： WANG Cong-yan lü yan-na WANG lei lIU Xue-yan TIAN Xingjun School of life Sciences Nanjing University School of Environmental Sciences Jiangsu University

We used a litterbag method to investigate litter decomposition and related soil degradative enzyme activities across four seasons in a broad-leaved forest and a coniferous forest on Zijin Mountain in sub-tropical China. Across four seasons, we quantified litter mass losses, soil pH values, and related soil degradative enzyme activities. litter decomposition rates differed significantly by season. litter decomposi- tion rates of broadleaf forest leaves were higher than for coniferous for- ests needles across four seasons, and maximal differences in litter de- composition rates between the two litter types were found in spring.

关键词： broad-leaved forest coniferous forest litter decomposition soil degradative enzyme

Boosted sustained-release with iron-based MOF-derived mesoporouscarbon-spheres as a nitroimidazole drugs carrier

在线全文

学校读者我要写书评

暂无评论

Particuology 2024年第3期86卷 269-280页

作者： Danping Wu Jiaying Zou Junyi Chen yan li na Ma Wei Dai College of Chemistry and Materials Science Zhejiang Normal UniversityJinhua321004China College of life Sciences Zhejiang Normal UniversityJinhua321004China College of Geography and Environmental Sciences Zhejiang Normal UniversityJinhua321004China

Metal-organic framework(MoF)with a buildable internal structure has aroused great interest focus as self-sacrificing precursors of porous carbon(PC).However,as a drug carrier,the MOF-derived PC developed thus far are generally composed of irregular powder shape due to their crystalline nature,which consequently causing the cerebral infarction,cerebral thrombosis,and other blood *** this article,we propose a novel approach to constructing amorphous carbon microspheres(AcMs)by dis-torting the topological network through hydrothermal treatment precursors of MIl-101(Fe).Then,a distinctive MIl-101(Fe)-derived spherical porous carbons(MSPC)is achieved through high temperature calcination toward *** of the glucose initial concentration and hydrothermal treatment time on the sphericity of the as-prepared mesoporous MsPC were investigated in *** the loading capacities and sustained-release performances of nitroimidazole drugs over MsPC through simulation internal environment of human body at different pH values was systematically *** nitro-imidazole drugs loading rate and release time of MsPC are 10% and 17 h under preferred ***,the MSPC exhibited very low toxicity on Hela cells and 293T cells at the concentrations tested(10-800μg ml^(-1)).This study,therefore,supports the potential of the mesoporous carbon spheres as a carrierfor nitroimidazole drug delivery.

关键词： Ornidazole Metronidazole Carbon spheres Sustained-release performance Biocompatibility

Ginsenoside Rd Induces Differentiation of Myeloid leukemia Cells via Regulating ERK/GSK-3βSignaling Pathway

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2024年第7期30卷 588-599页

作者： JIANG Yu-xia ZHAO yan-na YU Xiao-ling YIN li-ming Department of Hematology Tongde Hospital of Zhejiang ProvinceHangzhou310012China Institute of Hematology Research the First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine)Hangzhou310006China

Objective To investigate the role of ginsenoside Rd(GRd)in acute myeloid leukemia(AMl)cell *** AMl cells were treated with GRd(25,50,100 and 200µg/ml),retinoic acid(RA,0.1g/l)and PD98059(20 mg/ml)for 72 h,cell survival was detected by methylthiazolyldiphenyl-tetrazolium bromide and colony formation assays,and cell cycle was detected by flow *** morphology and differentiation were observed by Wright-Giemsa staining,peroxidase chemical staining and cellular immunochemistry assay,*** protein expression levels of GATA binding protein 1(GATA-1),purine rich Box-1(PU.1),phosphorylated-extracellular signal-related kinase(p-ERK),ERK,phosphorylated-glycogen synthase kinase-3β(p-GSK3β),GSK3βand signal transducer and activator of transcription 1(STAT1)were detected by Western ***-six mice were randomly divided into 3 groups using a random number table:model control group(non-treated),GRd group[treated with 200 mg/(kg·d)GRd]and homoharringtonine(HTT)group[treated with 1 mg/(kg·d)HTT].A tumor-bearing nude mouse model was established,and tumor weight and volume were *** of subcutaneous tumor tissue were observed after hematoxylin and eosin ***1 and GATA-1 expressions were detected by immunohistochemical *** The cell survival was inhibited by GRd in a dose-dependent manner and GRd caused G0/G1 cell arrest(pleukemia cell differentiation,showing increased expressions of peroxidase and specific proteins concerning erythrogenic or granulocytic differentiation(plicited upregulation of p-ERK,p-GSK-3βand STAT1 expressions in cells,and reversed the effects of PD98059 on inhibiting the expressions of peroxidase,GATA-1 and PU.1(Plume of mice were decreased,and tumor cells underwent massive apoptosis and necrosis(Plevel was decreased,and GATA-1 level was significantly increased in subcutaneous tumor ti

关键词： ginsenoside Rd myeloid leukemia survival differentiation extracellular signal-related kinase signaling pathway

Nickel-catalyzed carbonylative four-component 1,4-dicarbofunctionalization of 1,3-enynes

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第6期67卷 2029-2038页

作者： yan Zhao Qi-Chao Shan Hong Xin Pin Gao Xu yang Xin-Hua Duan li-na Guo Department of Chemistry School of ChemistryXi’an Key Laboratory of Sustainable Energy Material Chemistry and Engineering Research Center of Energy StorageMaterials and DevicesMinistry of EducationXi’an Jiaotong UniversityXi’an710049China School of Electrical Engineering Xi’an Jiaotong UniversityXi’an710049China

An efficient Ni-catalyzed four-component 1,4-carbocarbonylation of 1,3-enynes with activated alkyl halides and arylboronic acids under atmospheric pressure of CO is *** tuning the electronic and steric effects of alkyl radicals,both electronrich and electron-deficient 1,3-enynes were compatible with this *** protocol features mild conditions,broad substrate scope,excellent functional group compatibility and facile gram-scale synthesis,providing a practical approach to the quaternary carbon center-containing allenyl *** study revealed that the acyl-NiIIspecies plays an important role in both the coupling and the alkyl radical generation processes.

关键词： Ni catalysis four-component 1 4-carbocarbonylation 1 3-enynes

同方期刊数据库

Effects of lactobacillus paracasei N1115 on gut microbial imbalance and liver function in patients with hepatitis B-related cirrhosis

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第11期30卷 1556-1571页

作者： yan-Chao Hu Xiang-Chun Ding Hui-Juan liu Wan-long Ma Xue-yan Feng li-na Ma Department of Infectious Disease General Hospital of Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina Infectious Disease Clinical Research Center of Ningxia Yinchuan 750004Ningxia Hui Autonomous RegionChina

BACKGROUND Hepatitis B cirrhosis(HBC)is a chronic disease characterized by irreversible diffuse liver damage and aggravated by intestinal microbial imbalance and metabolic *** the relationship between certain single probiotics and HBC has been explored,the impact of the complex ready-to-eat lactobacillus paracasei N1115(lP N1115)supplement on patients with HBC has not been *** To compare the changes in the microbiota,inflammatory factor levels,and liver function before and after probiotic treatment in HBC *** This study included 160 HBC patients diagnosed at the General Hospital of Ningxia Medical University between October 2018 and December *** were randomly divided into an intervention group that received lP N1115 supplementation and routine treatment and a control group that received routine treatment *** samples were collected at the onset and conclusion of the 12-wk intervention *** structure of the intestinal microbiota and the levels of serological indicators,such as liver function and inflammatory factors,were *** Following lP N1115 intervention,the intestinal microbial diversity significantly increased in the intervention group(Pnal microbiota was characterized by an increase in the proportions of probiotic microbes and a reduction in harmful ***,the intervention group demonstrated notable improvements in liver function indices and significantly lower levels of inflammatory factors(PlUSION lP N1115 is a promising treatment for ameliorating intestinal microbial imbalance in HBC patients by modulating the structure of the intestinal microbiota,improving liver function,and reducing inflammatory factor levels.

关键词： Hepatitis B cirrhosis N1115 ready-to-eat lactobacillus Inflammation liver function lachnospiraceae incertae sedis Probiotic

Exploring predictive markers for liver failure post-hepatectomy in hepatocellular carcinoma patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2024年第5期16卷 1482-1484页

作者： Shi-yan Zhang Xiong-Jian Ma Xue-Xia Zhu na Cai Department of Clinical laboratory Fuding HospitalFujian University of Traditional Chinese MedicineFuding 355200Fujian ProvinceChina

This letter to the editor addresses the study titled“Predictive value of NlR,Fib4,and APRI in the occurrence of liver failure after hepatectomy in patients with hepatocellular carcinoma”by Kuang et al in the World Journal of Gastrointestinal *** study acknowledges the comprehensive patient data analysis while suggesting that there is a need for further discussion on the clinical applicability of these markers across diverse patient *** letter recommends prospective studies for validation and considers the influence of confounding *** finding underscores the significance of this study in improving hepatocellular carcinoma management.

关键词： Neutrophil-to-lymphocyte ratio Hepatocellular carcinoma liver failure Hepatectomy letter to the Editor Commentary

Evaluating serum CXCl12,sCD22,lp-PlA2 levels and ratios as biomarkers for diagnosis of Alzheimer's disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2024年第3期14卷 380-387页

作者： Zeng-ling liu Fei-Fei Hua lei Qu na yan Hui-Fang Zhang Department of Neurology Dongying People's HospitalDongying 257000Shandong ProvinceChina

BACKGROUND Grasping the underlying mechanisms of Alzheimer's disease(AD)is still a work in progress,and existing diagnostic techniques encounter various ***,the discovery of dependable biomarkers is essential for early detection,tracking the disease's advancement,and steering treatment *** To explore the diagnostic potential of serum CXCl12,sCD22,lp-PlA2,and their ratios in AD,aiming to enhance early detection and inform targeted treatment *** The study was conducted in Dongying people's Hospital from January 2021 to December *** included 60 AD patients(AD group)and 60 healthy people(control group).Using a prospective case-control design,the levels of CXCl12,sCD22 and lp-PlA2 and their ratios were detected by enzyme-linked immunosorbent assay kit in the diagnosis of *** differences between the two groups were analyzed by statistical methods,and the corresponding ratio was constructed to improve the specificity and sensitivity of *** Serum CXCl12 levels were higher in the AD group(47.2±8.5 ng/ml)than the control group(32.8±5.7 ng/ml,Ple sCD22 levels were lower(14.3±2.1 ng/ml vs 18.9±3.4 ng/ml,Plp-PlA2 levels were also higher in the AD group(112.5±20.6 ng/ml vs 89.7±15.2 ng/ml,Pl12/sCD22(3.3 vs 1.7,Plp-PlA-2/sCD22 ratios(8.0 vs 5.2,Pnalysis confirmed high sensitivity and specificity of these markers and their ratios in distinguishing AD,with area under the curves ranging from CONClUSION Serum CXCl12 and lp-PlA2 levels were significantly increased,while sCD22 were significantly decreased,as well as increases in the ratios of CXCl12/sCD22 and lp-PlA2/sCD22,are closely related to the onset of *** biomarkers and their ratios can be used as potential diagnostic indicators for AD,providing an important clinical reference for early intervention and treatment.

关键词： Alzheimer's disease Biomarkers CXCl12 sCD22 lp-PlA2

Strong-coupling superconductivity with Tc above 70 K in Be-decorated monolayer T-graphene

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2024年第1期67卷 99-105页

作者： liu yang Peng-Fei liu Hao-Dong liu Ya-Ping li na Jiao Hong-yan lu Bao-Tian Wang Ping Zhang School of Physics and Physical Engineering Qufu Normal UniversityQufu 273165China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Spallation Neutron Source Science Center Dongguan 523803China Institute of Applied Physics and Computational Mathematics Beijing 100088China

Using first-principles calculations,we predict a new type of two-dimensional(2D)beryllium(Be)-decorated T-graphene named BeC_(2),where Be atoms are inserted into C–C bonds linking the carbon tetrarings of *** band structure shows that BeC_(2)is metallic,thus,the possible phonon-mediated superconductivity is explored based on the Eliashberg *** calculated electron-phonon coupling(EPC)constantλis up to 4.07,and the corresponding superconducting critical temperature(Tc)is 72.1 K,approaching the liquid nitrogen *** reason for the high Tc is the strong *** it is proved to be an anisotropic single-gap superconductor by analyzing the superconducting gap?kof BeC_(2).The electronic susceptibility calculation shows strong nesting effect in BeC_(2).Since rare 2D superconductors show such a strong EPC constantλwhich originates from the coupling between electrons in C-pzorbital and in-plane vibrations of Be and C atoms,the predicted BeC_(2)provides a new platform for investigating strong EPC 2D superconductor.

关键词： two-dimensional carbon-based superconductor electron-phonon coupling strong coupling high superconducting critical temperature