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Effects of ozonation and coagulation on effluent organic matter characteristics and ultrafiltration membrane fouling

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Journal of Environmental Sciences 2014年第6期26卷 1325-1331页

作者： kwon Jeong Dae-Sung Lee Do-Gun Kim Seok-Oh Ko Department of Civil Engineering Kyung Hee UniversityYongin 446-701 Korea Institute of Construction Technology KUMHO Engineering & ConstructionYongin 449-822 Korea

Effluent organic matter （EfOM） is the major cause of fouling in the low pressure membranes process for wastewater reuse. Coagulation and oxidation of biological wastewater treatment effluent have been applied for the fouling control of microfiltration membranes. However, the change in EfOM structure by pre-treatments has not been clearly identified. The changes of EfOM characteristics induced by coagulation and ozonation were investigated through size exclusion chromatography, UV/Vis spectrophotometry, fluorescence spectrophotometry and titrimetric analysis to identify the mechanisms in the reduction of ultrafiltration （UF） membrane fouling. The results indicated that reduction of flux decline by coagulation was due to modified characteristics of dissolved organic carbon （DOC） content. Total concentration of DOC was not reduced by ozonation. However, the mass fraction of the molecules with molecular weight larger than 5 kDa, fluorescence intensity, aromaticity, highly condensed chromophores, average molecular weight and soluble microbial byproducts decreased greatly after ozonation. These results indicated that EfOM was partially oxidized by ozonation to low molecular weight, highly charged compounds with abundant electron- withdrawing functional groups, which are favourable for alleviating UF membrane flux decline.

关键词： effluent organic matter fouling ultrafiltration oxidation molecular weight distribution acidity

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Throughput Enhancement for Short Packets in the Wireless Packet Networks

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Throughput Enhancement for Short Packets in the Wireless Pac...

Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue

第七届国际信号处理会议

作者： Yeong-Hyeon kwon Mi-kyung Oh Dong-Jo Park Dept. of Electrical Engineering and Computer Science （EECS） Korea Advanced Institute of Science and Technology （KAIST） 373-1 Guseong-dong Yuseong-gu Daejon 305-701 Republic of Korea Dept. of Electrical Engineering and Computer Science （EECS） Korea Advanced Institute of Science and Technology （KAIST） 373-1 Guseong-dong Yuseong-gu Daejon 305-701 Republic of Korea Dept. of Electrical Engineering and Computer Science （EECS） Korea Advanced Institute of Science and Technology （KAIST） 373-1 Guseong-dong Yuseong-gu Daejon 305-701 Republic of Korea

We propose a novel transmission scheme suitable for short packet transmission over wireless channels. The proposed scheme is characterized by two schemes: 1) multicopy trans- mission per transmissi

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Molecular Plant 2016年第6期9卷 870-884页

作者： Shin Ae Lee Sejeong Jang Eun kyung Yoon Jung-Ok Heo Kwang Suk Chang Ji Won Choi Souvik Dhar Gyuree Kim Jeong-Eun Choe Jae Bok Heo Chian kwon Jae-Heung Ko Yong-Sic Hwang Jun Lim Department of Systems Biotechnology Konkuk University Seour 05029 Korea Department of Molecular Biotechnology Dong-A University Busan 49201 Korea Department of Molecular Biology Dankook University Yongin 16890 Korea Department of Plant and Environmental New Resources Kyung Hee University Yongin 17104 Korea These authors contributed equally to this article. Present address: The Sainsbury Laboratory University of Cambridge Cambridge CB2 1LR United Kingdom Present address: Department of Life Science Research Institute for Natural Sciences Hanyang University Seoul 04763 Korea

In multicellular organisms, controlling the timing and extent of asymmetric cell divisions （ACDs） is crucial for correct patterning. During post-embryonic root development in Arabidopsis thaliana, ground tissue （GT） maturation involves an additional ACD of the endodermis, which generates two different tissues： the endo- dermis （inner） and the middle cortex （outer）. It has been reported that the abscisic acid （ABA） and gibberellin （GA） pathways are involved in middle cortex （MC） formation. However, the molecular mechanisms under- lying the interaction between ABA and GA during GT maturation remain largely unknown. Through transcriptome analyses, we identified a previously uncharacterized C2H2-type zinc finger gene, whose expression is regulated by GA and ABA, thus named GAZ （GA- AND ABA-RESPONSIVE ZINC FINGER）. Seedlings ectopically overexpressing GAZ （GAZ-OX） were sensitive to ABA and GA during MC formation, whereas GAZ-SRDX and RNAi seedlings displayed opposite phenotypes. In addition, our results indicated that GAZ was involved in the transcriptional regulation of ABA and GA homeostasis. In agreement with pre- vious studies that ABA and GA coordinate to control the timing of MC formation, we also confirmed the unique interplay between ABA and GA and identified factors and regulatory networks bridging the two hor- mone pathways during GT maturation of the Arabidopsis root.

关键词： ABA GA GRAS ground tissue root development transcription factor

BRAF mutation in multiple primary cancer with colorectal cancer and stomach cancer

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Gastroenterology Report 2013年第1期1卷 70-74页

作者： Seung-Hyun Lee Byung-kwon Ahn Sung-Uhn Baek Hee-kyung Chang Department of Surgery and Pathology Kosin University College of MedicineBusanKorea

Aims:Recently,BRAF mutation testing has been introduced as a marker in differentiating Lynch syndrome from sporadic colorectal cancers or in predicting colorectal cancers with worse *** with hereditary predisposition to cancer development are at an increased risk of developing multiple primary *** purpose of this study is to identify mutation in the BRAF gene in multiple primary cancers with colorectal cancer and stomach ***:BRAF mutation was analysed in 45 patients with colorectal cancer and stomach cancer,synchronously or ***:Mean age was 64.07 years(range:47–83 years).For the colorectal cancer,tumors were located at the sigmoid colon in eight patients(17.8%)and at the rectum in 22 patients(48.9%).Twenty-three patients(51.1%)had synchronous *** patients(8.9%)had family members with *** mutation was identified in three patients(6.7%).All three of these patients had metachronous *** colorectal cancers were located in the sigmoid colon(1 patient)and the rectum(2 patients).Conclusions:BRAF mutation rate was low in the multiple primary cancer with colorectal cancer and stomach *** only BRAF gene study,it was not possible to identify any correlation with family history of colorectal *** study means considering other genes–MSI,MSH2,MLH1,MSH6.

关键词： multiple primary cancer colorectal cancer stomach cancer BRAF mutation

Amelioration effects of traditional Chinese medicine on alcohol-induced fatty liver

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World Journal of Gastroenterology 2005年第35期11卷 5512-5516页

作者： Hyun-Jeong kwon Yun-Young Kim Se-Young Choung Department of Hygienic Chemistry College of Pharmacy Kyung Hee University Seoul 130-701 South Korea

AIM： To examine the effects of traditional Chinese medicine （TCM） on alcohol-induced fatty liver in rats. TCM consists of Astragalus membranaceus, Morus alba, Crataegus pinnatifida, Alisma orientale, Salvia miltiorrhiza, and Pueraria lobata. METHODS： The rats were separated randomly into five groups. One （the CD group） was fed a control diet for 10 wk, another （the ED group） fed an ethanol-containing isocaloric liquid diet for 10 wk, and the last three （the TCM group） were fed an ethanol-containing isocaloric liquid diet for 10 wk and dosed orally with TCM （222 mg/kg.d, TCM222; 667 mg/kg·d, TCM667; and 2 000 mg/kg.d, TCM2000, respectively） weekly during the last 4 wk. RESULTS： ED group developed fatty liver according to lipid profile and liver histological findings. Compared with the control group, liver/body weight, serum triglyceride （TG） and total cholesterol （TC）, liver TG and TC, serum alanine aminotransferase （ALT） and aspartic aminotransferase （AST） significantly increased in the ED group. Whereas, in the rats administered with TCM, liver/body weight, serum TG and TC, liver TG and TC, serum ALT and AST were significantly decreased, and the degree of hepatic lipid droplets was markedly improved compared with those in the ED group. CONCLUSION： TCM treatment causes significant reduction in alcohol-induced lipid hepatic accumulation, reversing fatty liver and liver damage, and can be used as a remedy for alcoholic fatty liver.

关键词： Fatty liver Alcohol Astragalus membranaceus,Horus alba Crataegus pinnatifida Alisma orientale Salvia miltiorrhiza Pueraria Iobata

Programmed death ligand-1 expression and its prognostic role in esophageal squamous cell carcinoma

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World Journal of Gastroenterology 2016年第37期22卷 8389-8397页

作者： Ryul Kim Bhumsuk Keam Dohee kwon Chan-Young Ock Miso Kim Tae Min Kim Hak Jae Kim Yoon kyung Jeon In Kyu Park Chang Hyun Kang Dong-Wan Kim Young Tae Kim Dae Seog Heo Department of Internal Medicine Seoul National University HospitalSeoul 03080South Korea Cancer Research Institute Seoul National University College of MedicineSeoul 03080South Korea Department of Pathology Seoul National University HospitalSeoul 03080South Korea Department of Radiation Oncology Seoul National University HospitalSeoul 03080South Korea Department of Thoracic and Cardiovascular Surgery Seoul National University HospitalSeoul 03080South Korea

AIM To investigate the expression and prognostic role of programmed death ligand-1(PD-L1) in locally advanced esophageal squamous cell carcinoma(ESCC).METHODS A total of 200 patients with ESCC who underwent radical esophagectomy with standard lymphadenectomy as the initial definitive treatment in Seoul National University Hospital from December 2000 to April 2013 were eligible for this analysis. Tissue microarrays were constructed by collecting tissue cores from surgical specimens, and immunostained with antibodies directed against PD-L1, p16, and c-Met. Medical records were reviewed retrospectively to assess clinical outcomes. Patients were divided into two groups by PD-L1 status, and significant differences in clinicopathologic characteristics between the two groups were assessed. RESULTS Tumor tissues from 67 ESCC patients(33.5%) were PDL1-positive. Positive p16 expression was observed in 21 specimens(10.5%). The H-score for c-Met expression was ≥ 50 in 42 specimens(21.0%). Although PDL1-positivity was not significantly correlated with any clinical characteristics including age, sex, smoking/alcoholic history, stage, or differentiation, H-scores for c-Met expression were significantly associated with PDL1-positivity(OR = 2.34, 95%CI: 1.16-4.72, P = 0.017). PD-L1 expression was not significantly associated with a change in overall survival(P = 0.656). In contrast, the locoregional relapse rate tended to increase(P = 0.134), and the distant metastasis rate was significantly increased(HR = 1.72, 95%CI: 1.01-2.79, P = 0.028) in patients with PD-L1-positive ESCC compared to those with PD-L1-negative *** PD-L1 expression is positively correlated with c-Met expression in ESCC. PD-L1 may play a critical role in distant failure and progression of ESCC.

关键词： Esophageal neoplasm Programmed death ligand-1 protein c-Met protein Prognosis p16INK4A protein

Foldable and washable textile-based OLEDs with a multi-functional near-room-temperature encapsulation layer for smart e-textiles

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npj Flexible Electronics 2021年第1期5卷 123-131页

作者： So Yeong Jeong Hye Rin Shim Yunha Na Ki Suk Kang Yongmin Jeon Seungyeop Choi Eun Gyo Jeong Yong Cheon Park Ha-Eun Cho Junwoo Lee Jeong Hyun kwon Sung Gap Im kyung Cheol Choi School of Electrical Engineering Korea Advanced Institute of Science and Technology(KAIST)DaejeonRepublic of Korea Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and Technology(KAIST)DaejeonRepublic of Korea Department of Clothing and Textiles Chonnam National UniversityGwangjuRepublic of Korea Department of Display and Semiconductor Engineering Sun Moon UniversityAsanRepublic of Korea Department of Chemical and Biomolecular Engineering and KI for the NanoCentury Korea Advanced Institute of Science and Technology(KAIST)DaejeonRepublic of Korea.

Wearable electronic devices are being developed because of their wide potential applications and user *** them,wearable organic light emitting diodes(OLEDs)play an important role in visualizing the data signal processed in wearable electronics to *** this study,textile-based OLEDs were fabricated and their practical utility was *** textilebased OLEDs exhibited a stable operating lifetime under ambient conditions,enough mechanical durability to endure the deformation by the movement of humans,and washability for maintaining its optoelectronic properties even in water condition such as rain,sweat,or *** this study,the main technology used to realize this textile-based OLED was multi-functional nearroom-temperature *** outstanding impermeability of TiO_(2)film deposited at near-room-temperature was *** internal residual stress in the encapsulation layer was controlled,and the device was capped by highly crosslinked hydrophobic polymer film,providing a highly impermeable,mechanically flexible,and waterproof encapsulation.

关键词： OLEDs layer film

Neuroprotective effects of roasted licorice,not raw form,on neuronal injury in gerbil hippocampus after transient forebrain ischemia

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Acta Pharmacologica Sinica 2006年第8期27卷 959-965页

作者： In-koo HWANG Soon-sung LIM Kyu-hyun CHOI Ki-yeon YOO Hyun-kyung SHIN Eun-ji KIM Jung-han YOONPARK Tae-cheon KANG Young-sup KIM Dae-young kwon Dong-woo KIM Won-kook MOON Moo-ho WON Korea Central Research Institute.Natural F&P Co Ltd Chunchon 200-160Korea Silver Biotechnology Research Center Korea Silver Biotechnology Research Center Department of Food Science and Nutrition Hallym UniversityChunchon 200-702Korea Medical Science Division Korea Research Institute of Chemical TechnologyYuseong.Daejeon 305-343Korea Korea Central Research Institute.Natural F&P Co Ltd Chunchon 200-160Korea Korea Silver Biotechnology Research Center

Aim:To observe neuroprotective effects of raw and roasted licorice against hy-poxia and ischemic ***:When elucidating the protective effects ofraw and roasted licorice,we analyzed the lactate dehydrogenase (LDH) releaseusing PC12 cells after hypoxia in an in vitro study and after transient forebrainischemia in an in vivo study on Mongolian ***:Raw and roastedlicorice significantly reduced LDH release from PC12 cells exposed to an hypoxicchamber for *** the roasted licorice-treated group,the decrease of LDH releasewas more pronounced compared to that of the raw licorice-treated *** licorice-treated animals,approximately 66%-71% of CA1 pyramidal cellsin the ischemic hippocampus were stained with cresyl violet compared to thecontrol ***,in the raw licorice-treated animals,no significantneuroprotection against ischemic damage was *** addition,ischemic ani-mals in roasted licorice-treated group maintained the Cu,Zn-superoxide dismutase(SOD1) activity and protein levels compared to the control group,while in rawlicorice-treated group SOD1 activity and protein levels were reduced *** pressure liquid chromatography analysis showed that non-polar compoundscontaining glycyrrhizin-degraded products,such as glycyrrhetinic acid (GA) andglycyrrhetinic acid monoglucuronide (GM),were increased in roasted ***:Roasted licorice had neuroprotective effects against ischemic dam-age by maintaining the SOD1 *** addition,the difference in protectiveability between raw and roasted licorice may be associated with non-polarcompounds,such as GA and GM.

关键词： transient ischemic attack roasted licorice raw licorice neurons PC12 cells hippocampus pyramidal cells Gerbillinae superoxide dismutase

Exploring ideal operative time for best outcomes in gastric cancer surgery:A multi-institutional study based on KLASS-07 database

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Chinese Journal of Cancer Research 2023年第6期35卷 660-674页

作者： Shin-Hoo Park Ye-rim Shin Hoon Hur Chang Min Lee Jae Seok Min Seung Wan Ryu Hyun Dong Chae Oh Jeong Chang-In Choi Kyo-Young Song Ho Goon Kim Ye Seob Jee Kwang Hee Kim Jeong Goo Kim kyung Sook Yang Hua Huang Sungsoo Park Division of Foregut Surgery Korea University College of MedicineSeoul 02841Republic of Korea Division of Foregut Surgery Korea University Anam HospitalSeoul 02841Republic of Korea Department of Surgery Ajou University School of MedicineSuwon 16499Republic of Korea Division of Foregut Surgery Korea University Ansan HospitalAnsan 15355Republic of Korea Department of Surgery Dongnam Institute of Radiological and Medical SciencesCancer CenterBusan 46033Republic of Korea Department of Surgery Keimyung University Dongsan Medical CenterDaegu 41931Republic of Korea Department of Surgery Catholic University of Daegu School of MedicineDaegu 42472Republic of Korea Department of Surgery Chonnam National University Medical SchoolHwasun 58128Republic of Korea Department of Surgery Pusan National University HospitalPusan 49241Republic of Korea Department of Surgery Catholic University of Seoul St Mary’s HospitalSeoul 06591Republic of Korea Department of Surgery Chonnam National University Medical SchoolGwangju 61469Republic of Korea Department of Surgery Dankook University College of MedicineCheonan 31116Republic of Korea Department of Surgery Busan Paik HospitalInje UniversityBusan 14905Republic of Korea Department of Surgery Daejeon St.Mary’s HospitalCollege of Medicinethe Catholic University of KoreaDaejeon 34943Republic of Korea Department of Biostatistics Korea University College of MedicineSeoul 02841Republic of Korea Department of Gastric Cancer and Soft Tissue Sarcoma Fudan University Shanghai Cancer CenterShanghai 200433China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200433China

Objective:While a rushed operation can omit essential procedures,prolonged operative time results in higher ***,the optimal operative time range remains *** study aimed to estimate the ideal operative time range and evaluate its applicability in laparoscopic cancer ***:A prospectively collected multicenter database of 397 patients who underwent laparoscopic distal gastrectomy were retrospectively *** ideal operative time range was statistically calculated by separately analyzing the operative time of uneventful ***,intraoperative and postoperative outcomes were compared among the shorter,ideal,and longer operative time ***:The statistically calculated ideal operative time was 135.4-165.4 *** longer operative time(LOT)group had a lower rate of uneventful,perfect surgery than the ideal or shorter operative time(IOT/SOT)group(2.8%vs.8.8%and 2.2%vs.13.4%,all P<0.05).Longer operative time increased bleeding,postoperative morbidities,and delayed diet and discharge(all P<0.05).Particularly,an uneventful,perfect surgery could not be achieved when the operative time exceeded 240 *** of ideal time range,SOT group achieved the highest percentage of uneventful surgery(13.4%),which was possible by surgeon's ability to retrieve a higher number of lymph nodes and perform≥150 gastrectomies ***:Operative time longer than the ideal time range(especially≥240 min)should be *** the essential operative procedure were faithfully conducted without compromising oncological safety,an operative time shorter than the ideal range leaded to a better *** to minimize operative time should be attempted with sufficient surgical experience.

关键词： Operative time laparoscopic surgery gastric cancer gastrectomy morbidity

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