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Analysis of dynamic smile and upper lip curvature in young Chinese

International Journal of Oral Science 2013年第1期5卷 49-53页

作者： Ling-Zhi Liang Wen-Jie Hu Yan-Ling Zhang kwok-hung chung Department of Periodontology Peking University School & Hospital of Stomatology Department of Restorative Dentistry University of Washington

During smile evaluation and anterior esthetic construction,the anatomic and racial variations should be considered in order to achieve better matching *** aims of this study were to validate an objective method for recording spontaneous smile process and to categorize the smile and upper lip curvature of Chinese Han-nationality *** hundred and eighty-eight Chinese Han-nationality youths(88 males and 100 females) ranged from 20 to 35 years of age were *** smiles were elicited by watching comical movies and the dynamics of the spontaneous smile were captured continuously with a digital video *** subjects’ smiles were categorized into three types:commissure,cuspid and gummy smile based on video editing software and final ***’ upper lip curvatures were also measured and divided into three groups:upward,straight and *** analysis was conducted to obtain intra-rater reliabilities on twice *** Pearson Chi-square test was used to compare differences for each parameters(α=0.05).In smile classification,60.6%commissure smile,33.5%cuspid smile and 5.9%gummy smile were *** upper lip measurement,26.1%upward,39.9%straight and 34.0%downward upper lip curvature were *** commissure smile group showed statistically significant higher percentage of straight(46.5%) and upward(40.4%) in upper lip curvatures(P<0.05),while cuspid smile group(65.1%) and gummy smile group(72.7%) showed statistically significant higher frequency in downward upper lip curvature(P<0.05).It is evident that differences in upper lip curvature and smile classification exist based on race,when comparing Chinese subjects with those of Caucasian descent,and gender.

关键词： Chinese Han nationality image processing smiles upper lip curvature

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Highly Accurate Golden Section Search Algorithms and Fictitious Time Integration Method for Solving Nonlinear Eigenvalue Problems

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 1317-1335页

作者： Chein-Shan Liu Jian-hung Shen chung-Lun Kuo Yung-Wei Chen Center of Excellence for Ocean Engineering Taiwan Ocean UniversityKeelung202301TaiwanChina Department of Marine Engineering Taiwan Ocean UniversityKeelung202301TaiwanChina

This study sets up two new merit functions,which are minimized for the detection of real eigenvalue and complex eigenvalue to address nonlinear eigenvalue *** each eigen-parameter the vector variable is solved from a nonhomogeneous linear system obtained by reducing the number of eigen-equation one less,where one of the nonzero components of the eigenvector is normalized to the unit and moves the column containing that component to the right-hand side as a nonzero input vector.1D and 2D golden section search algorithms are employed to minimize the merit functions to locate real and complex ***,the real and complex eigenvectors can be computed very accurately.A simpler approach to the nonlinear eigenvalue problems is proposed,which implements a normalization condition for the uniqueness of the eigenvector into the eigenequation *** real eigenvalues can be computed by the fictitious time integration method(FTIM),which saves computational costs compared to the one-dimensional golden section search algorithm(1D GSSA).The simpler method is also combined with the Newton iterationmethod,which is convergent very *** the proposed methods are easily programmed to compute the eigenvalue and eigenvector with high accuracy and efficiency.

关键词： Nonlinear eigenvalue problem quadratic eigenvalue problem two new merit functions golden section search algorithm fictitious time integration method

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Solitary extraovarian primary peritoneal carcinoma with direct invasion into the liver,diaphragm and lung without peritoneal dissemination or distant metastasis

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Hepatobiliary & Pancreatic Diseases International 2024年第3期23卷 322-325页

作者： Billy Ho hung Cheung Wong Hoi She Siu Lun Ho Albert Chi Yan Chan chung Mau Lo Tan To Cheung Department of Surgery The University of Hong KongHong KongChina Department of Pathology The University of Hong KongHong KongChina

To the Editor:Extraovarian primary peritoneal carcinoma(EOPPC)is an uncommon malignancy with many similarities to epithelial ovarian carcinoma in histological,clinical,and etiological aspects[1].This phenomenon is explained by their common embryonal origin,in which both develop from the coelomic epithelium in the early embryological *** their similarities,the incidence of EOPPC is significantly lower than that of epithelial ovarian carcinoma(6.78 cases per million vs.120.5 cases per million)[1].

关键词： peritoneal invasion metastasis

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翻转课堂教学模式在口腔修复学本科教育中的探索

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中国继续医学教育 2021年第11期13卷 74-78页

作者：斯露婕王一如徐婧秋杨海萍 kwok-hung chung 傅柏平浙江大学医学院附属口腔医院修复科浙江杭州310006 浙江省口腔生物医学研究重点实验室浙江杭州310006 华盛顿大学口腔修复科美国华盛顿98195

目的翻转课堂是一种新兴的教育模式,本次研究希望对其在口腔修复学本科教学中的有效性进行探究。方法本次研究通过在口腔修复学本科教育中组织翻转课堂教学,并在课后对参与的学生进行问卷调查,对学生满意度及教学效率等方面进行统计研... 详细信息

目的翻转课堂是一种新兴的教育模式,本次研究希望对其在口腔修复学本科教学中的有效性进行探究。方法本次研究通过在口腔修复学本科教育中组织翻转课堂教学,并在课后对参与的学生进行问卷调查,对学生满意度及教学效率等方面进行统计研究。结果86%的学生认为通过翻转课堂增加了对课程内容的理解,但与此同时55%的学生不能够很好的理解他组的展示内容,并且强调了教师在翻转课堂过程中应扮演引导者的角色。结论翻转课堂是一种提升教学效果的有效手段,但是如何组织更加高效的课前学习,进行课程设计等等问题仍然值得思考和进一步研究。

关键词：翻转课堂口腔修复学本科教育问卷调查 TBL 主动学习教育

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Tourism-Oriented Cultural Product Design: A Case Study of Yami Culture in Lanyu

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Open Journal of Applied Sciences 2024年第9期14卷 2506-2514页

作者： hung-Cheng Tsai Yuhsiu Liu chung-Ming Tsai Department of Industrial Design National Kaohsiung University of Science and Technology Kaohsiung City

Due to the prevalence of modern commerce and mainstream culture, many indigenous cultures around the world are rapidly diminishing. These cultures, with their unique primitiveness distinct from modern culture, often attract tourists. This study integrates the indigenous Yami culture of Lanyu Island, Taiwan Region, into innovative designs from the perspective of tourists’ understanding of the local culture. In this way, tourists can experience the harmonious coexistence of the Yami tribe and nature, while these culturally rich products foster deeper experiential and emotional resonance. This study employs the Mandala thinking method for concept expansion and the Osborn checklist method for the analysis and transformation of design elements. Subsequently, designers were invited to conduct on-site travel experiences, leading to the creation of a series of Yami cultural products. Through the evaluation and validation of cultural product assessment indicators, functional commercialized products were ultimately produced. This study aims to establish a design process for cultural products through this design case. It seeks to help users recall their Lanyu Island travel experiences and appreciate the often-overlooked cultural beauty, thereby raising awareness of cultural preservation.

关键词： Cultural Innovation Cultural Product Yami Culture Tourism Lanyu

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Unique anti-angiogenic effects,pharmacological targets and therapeutic mechanisms of Chinese herbal medicines for endometriosis

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Genes & Diseases 2024年第5期11卷 63-65页

作者： Bo Liang Rui Dong Sze Wan hung Yiran Li Yuezhen Lin Ling Wu Tao Zhang Gene Chi Wai Man Hui Xu Jacqueline Pui Wah chung Chi Chiu Wang Guangdong Provincial Key Laboratory of Marine Biotechnology Institute of Marine SciencesShantou UniversityShantouGuangdong 515063China Department of Obstetrics and Gynaecology The Chinese University of Hong KongHong Kong SARChina Reproduction and Development Laboratory Li Ka Shing Institute of Health SciencesThe Chinese University of Hong KongHong Kong SARChina School of Biomedical Sciences The Chinese University of Hong KongHong Kong SARChina Chinese University of Hong Kong-Sichuan University Joint Laboratory in Reproductive Medicine The Chinese University of Hong KongHong Kong SARChina

Endometriosis is a common and benign angiogenesisdependent gynecological disorder,which refers to the proliferation and growth of endometrium-like tissues with neovasculature formation outside of the uterus.1 Available medical treatments for endometriosis containing hormonal and non-hormonal treatments had been limited for longterm usage by their side effects.2 Ideal medical treatment for endometriosis with efficacy to relieve symptoms and suppress endometriotic lesion growth and minimal side effects has been longing for decades.3 Angiogenesis is a promising therapeutic target for endometriosis.

关键词： therapeutic endometriosis herbal

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Distinct molecular targets of ProEGCG from EGCG and superior inhibition of angiogenesis signaling pathways for treatment of endometriosis

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Journal of Pharmaceutical Analysis 2024年第1期14卷 100-114页

作者： Sze Wan hung Massimiliano Gaetani Yiran Li Zhouyurong Tan Xu Zheng Ruizhe Zhang Yang Ding Gene Chi Wai Man Tao Zhang Yi Song Yao Wang Jacqueline Pui Wah chung Tak Hang Chan Roman A.Zubarev Chi Chiu Wang Department of Obstetrics&Gynaecology The Chinese University of Hong KongHong KongChina Division of Physiological Chemistry I Department of Medical Biochemistry and BiophysicsKarolinska InstitutetStockholmSE 17177Sweden Chemical Proteomics Core Facility Department of Medical Biochemistry and BiophysicsKarolinska InstitutetStockholmSE 17177Sweden Unit of Chemical Proteomics Science for Life Laboratory(SciLifeLab)StockholmSE 17177Sweden Center for Reproductive Medicine Henan Key Laboratory of Reproduction and GeneticsThe First Affiliated Hospital of Zhengzhou UniversityZhengzhou450003China Department of Chemistry McGill UniversityMontrealH3A2K6Canada Department of Pharmacological&Technological Chemistry I.M.Sechenov First Moscow State Medical UniversityMoscow119146Russia Reproduction and Development Li Ka Shing Institute of Health SciencesThe Chinese University of Hong KongHong KongChina School of Biomedical Sciences The Chinese University of Hong KongHong KongChina Chinese University of Hong Kong-Sichuan University Joint Laboratory in Reproductive Medicine The Chinese University of Hong KongHong KongChina

Endometriosis is a common chronic gynecological disease with endometrial cell implantation outside the *** is a major pathophysiology in *** previous studies have demonstrated that the prodrug of epigallocatechin gallate(ProEGCG)exhibits superior anti-endometriotic and anti-angiogenic effects compared to epigallocatechin gallate(EGCG).However,their direct binding targets and underlying mechanisms for the differential effects remain *** this study,we demonstrated that oral ProEGCG can be effective in preventing and treating ***,1D and 2D Proteome Integral Solubility Alteration assay-based chemical proteomics identified metadherin(MTDH)and PX domain containing serine/threonine kinase-like(PXK)as novel binding targets of EGCG and ProEGCG,*** simulation and BioLayer interferometry were used to confirm their binding *** results showed that MTDH-EGCG inhibited protein kinase B(Akt)-mediated angiogenesis,while PXK-ProEGCG inhibited epidermal growth factor(EGF)-mediated angiogenesis via the EGF/hypoxia-inducible factor(HIF-1a)/vascular endothelial growth factor(VEGF)*** vitro and in vivo knockdown assays and microvascular network imaging further confirmed the involvement of these signaling ***,our study demonstrated that ProEGCG has superior therapeutic effects than EGCG by targeting distinct signal transduction pathways and may act as a novel antiangiogenic therapy for endometriosis.

关键词： Molecular targets ProEGCG EGCG Angiogenesis Treatment Endometriosis

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On a Heuristic Point of View about the Generalization of Curie Law to Cosmic Higgs Fields with the Casimir Effect

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Journal of Applied Mathematics and Physics 2024年第9期12卷 3135-3147页

作者： hung-Te Henry Su Po-Han Lee Department of Physics National Chung Cheng University Chia-Yi Department of Electro-Optical Engineering National Taipei University of Technology Taipei City The Affiliated Senior High School of National Taiwan Normal University Taipei City

Condensed state physics demonstrates that the Curie temperature is the point at which spontaneous magnetization drops to zero, marking the critical transition where ferromagnetic or ferrimagnetic materials transform into paramagnetic substances. Below the Curie temperature, a material remains ferromagnetic;above it, the material becomes paramagnetic, with its magnetic field easily influenced by external magnetic fileds. For example, the Curie temperature of iron (Fe) is 1043 K, while that of neodymium magnets ranges from 583 to 673 K. From both physics and mathematics perspectives, examining the temperature properties of materials is essential, as it provides valuable insights into their electromagnetic and thermodynamic behaviors. This paper makes a bold assumption and, for the first time, carefully verifies the existence of a Casimir temperature at 0.00206 K under conditions of one-atomic spacing.

关键词： Curie Temperature Curie Point Casimir Temperature Critical Point Fields Materials One-Atomic Spacing

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Numerical characteristics of the full operator hybrid simulation method

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Earthquake Engineering and Engineering Vibration 2011年第3期10卷 453-463页

作者： chung-Chan hung Yong-Song Chen Department of Civil Engineering Central University （NCU） Chinese Taipei Department of Mechanical Engineering Chung Cheng University （NCCU） Chinese Taipei

The full operator method （FOM） has been proposed to overcome some of the shortcomings of the commonly used operator splitting method （OSM）. In particular, the FOM is improved by increasing the accuracy of both the predictor and corrector using the estimated tangent stiffness of the tested structure. The numerical characteristics of the FOM, including stability and accuracy, are investigated in this study. It is shown that FOM is conditionally stable. The stability and accuracy characteristics are dependent on the accuracy of the estimated tangent stiffness and the parameters associated with the acceleration variation in the time-stepping integration method. Mass-spring systems with different types of nonlinearity, including hardening, stiffening, and softening behavior, are used to evaluate the performance of the FOM. It is found that the FOM can capture these types of nonlinearity with satisfactory accuracy. Using a prototype 12-story composite coupled wall system, the influences of the strong nonlinearity of the system as well as the displacement control errors from hydraulic actuators on the performance of the FOM are explored. The results show that the FOM is capable of generating reasonably accurate results despite the presence of strong structural nonlinearity and displacement control errors.

关键词： hybrid simulation tangent stiffness numerical characteristic composite coupled wall system collapse behavior nonlinear behavior

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Functional Design of A Series of Submerged Breakwaters for Coastal Protection Against Waves

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China Ocean Engineering 2010年第3期24卷 553-564页

作者： Li-hung TSAI Chih-chung WEN Center of Harbor and Marine Technology Institute of TransportationMinistry of Transportation and Communications Department of Safety Health and Environmental EngineeringHungkuang University

The purpose of this paper is to develop a functional method for designing a series of submerged breakwaters on practical topography. The method is used to verify the feasibility and effectiveness of Bragg breakwaters for coastal protection by using field topography. The first part of this paper provides definitions and procedures needed in the design process for applying the mechanism of Bragg reflection. Next, Bragg breakwaters are designed on the basis of the cross-sectional topography and then on the plane topography of the Mi-Tuo coast by following the proposed process and procedure. Numerical modeling （Hsu et al., 2003; Wen and Tsai, 2008） was used as a design and assessment tool. Finally, the effectiveness and feasibility of a Bragg breakwater was assessed by practical cases. Based on the mechanism of Bragg reflection, an optimum layout for a series of submerged breakwaters is proposed to protect the Mi-Tuo coast. The results indicate that the proper layout of a series of submerged creakwaters can achieve the objective of beach protection.

关键词： a series of submerged breakwaters Bragg reflection coastal protection

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