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Cell-type continuous electromagnetic radiation system generating millimeter waves for active denial system applications

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Defence Technology（防务技术） 2022年第10期18卷 1895-1913页

作者： Sun-Hong min Ohjoon Kwon Matlabjon Sattorov Seontae Kim In-Keun Baek Seunghyuk Park Ranjan Kumar Barik Anirban Bera Dongpyo Hong Seonmyeong Kim Bong Hwan Hong Chawon Park Sukhwal Ma minho Kim Kyo Chul Lee Yong Jin Lee Han Byul Kwon Young Joon Yoo Sang Yoon Park Gun-sik Park Korea Institute of Radiological and Medical Sciences(KIRAMS) Seoul01812South Korea Institute for Basic Science Center for Axion and Precision Physics ResearchDaejeon34141South Korea Center for THz-Driven Biomedical Systems Department of Physics and AstronomyCollege of Natural SciencesSeoul National UniversitySeoul08826South Korea Center for Applied Electromagnetic Research Advanced Institute of Convergence TechnologySuwonGyeonggi-do16229South Korea R&D Department Seoul-TeracomInc.Suwon16229South Korea Mechatronics R&D Center Samsung Electronics Co.Ltd.Hwasung18448South Korea Hanwha Corporation Gumi730-030South Korea Council of Scientific and Industrial Research Central Electronics Engineering Research InstitutePilani333031India Home Economics Education/Biosystems and Biomedical Sciences Korea UniversitySeoul02841South Korea Current affiliation of Seontae Kim:Young IN ACE 1 F60Anyangcheondong-roDongan-guAnyang-siGyeonggi-do14042South Korea.

The cell-type continuous electromagnetic radiation system is a demonstration device capable of generating high-power millimeter electromagnetic waves of a specific wavelength and observing their effects on living *** irradiates a biological sample placed in a 30×30×50 cm^(3)cell with electromagnetic waves in the 3.15-mm-wavelength region(with an output of≥1 W)and analyzes the temperature change of the sample.A vacuum electronic device-based coupled-cavity backward-wave oscillator converts the electron energy of the electron beam into radiofrequency(RF)energy and radiates it to the target through an antenna,increasing the temperature through the absorption of RF energy in the *** system causes pain and ultimately reduces combat power.A cell-type continuous electromagnetic radiation system consisting of four parts—an electromagnetic-wave generator,a highvoltage power supply,a test cell,and a system controller—generates an RF signal of≥1 W in a continuous waveform at a 95-GHz center frequency,as well as a chemical solution with a dielectric constant similar to that of the skin of a living *** increase of 5°C lasting approximately 10 s was confirmed through an experiment.

关键词： Millimeter waves Terahertz waves Coupled-cavity backward wave oscillator(CCBWO) Cell-type continuous electromagnetic radiation Active denial system(ADS) Directed-energy weapon(DEW)

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Temporal population dynamics of dinoflagellate Prorocentrum minimum in a semi-enclosed mariculture pond and its relationship to environmental factors and protozoan grazers

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Chinese Journal of Oceanology and Limnology 2010年第1期28卷 75-81页

作者：许恒龙 min Gi-sik CHOI Joong-Ki 朱明壮姜勇 AL-RASHEID Khaled A.S. Laboratory of Protozoology KLMOcean University of China Department of Biological Sciences Inha University Department of Oceanography Inha University Zoology Department King Saud University

The ecological processes and interrelationships between protists,either autotrophic or heterotrophic,and environmental factors in mariculture ponds are largely *** study investigated the temporal dynamics of potentially harmful dinoflagellate,Prorocentrum minimum (Pavillard) Schiller,and its relationship to physico-chemical factors and protozoan grazers over a complete cycle in a semi-enclosed shrimp-farming pond near Qingdao,Northern *** occurred frequently in low numbers from June to August,followed by a sharp increase from the middle of August,reaching a single maximum peak value of 2.2×105 cells L-1 in *** variation in abundance was positively correlated with dissolved nitrogen,but showed a significant inverse relationship to abundance of the dominant ciliates,Tintinnopsis lohmanni and Askenasia *** results provide statistical evidence that the number of *** increased with increasing nitrogen,and the suppression or shortening of algal bloom may be associated with protozoan grazers,such as Tintinnopsis lohmanni,in mariculture ponds.

关键词：海水养殖池塘微小原甲藻食草动物原生动物环境因素时空动态半封闭种群动态

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Influence of protein characteristics and the proportion of gluten on end-use quality in Korean wheat cultivars

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Journal of Integrative Agriculture 2018年第8期17卷 1706-1719页

作者： Seong-Woo Cho Chon-sik Kang Hyeon Seok Ko Byung-Kee Baik Kwang-min Cho Chul Soo Park Department of Crop Science & Biotechnology Chonbuk National University National Institute of Crop Science Rural Development Administration Farm & Agribusiness Management Division Rural Development Administration USDA-ARS CSWQRU Soft Wheat Quality Laboratory Research Center of Bioactive Materials Chonbuk National University

The effects of protein characteristics and the proportion of gluten on end-use quality in 13 Korean wheat cultivars for three years were verified in this study. Year, cultivar, and the interaction between the year and the cultivar influenced protein characteristics, the proportion of gluten except for γ-and ω-gliadin using RP-HPLC(reversed-phase high-performance liquid chromatography), and end-use quality. Protein characteristics and the proportion of gluten in Korean wheat cultivars were between those of Australian standard white(ASW) and hard wheat(AH). Korean wheat cultivars exhibited a higher average α+β gliadin proportion than imported wheat, a γ-gliadin proportion similar to that of dark northern spring wheat, and the same ω-gliadin proportion as AH. They showed a bread-loaf volume intermediate between those of ASW and AH and a texture of cooked noodles similar to that of soft white wheat, but less springiness than imported wheat. The cookie diameter of Korean wheat cultivars was similar to that of hard red winter wheat. There was a correlation between bread-loaf volume and protein characteristics, except for the protein content in Korean wheat cultivars. Springiness and cohesiveness of cooked noodles were not correlated with protein characteristics, while hardness was correlated with the protein content and water absorption of a mixograph. Cookie diameter was negatively correlated with the sodium dodecyl sulfate(SDS) sedimentation volume and water absorption of a mixograph. The end-use quality was not correlated with any proportion of gluten composition. Principal component analysis(PCA) showed that the proportion of gluten was not related to the quality of the bread(both PCs, 81.3%), noodle(77.7%), and cookie(82.4%). PCA explained that Keumkang is suitable for superior bread, while Uri is good for cooked noodles and cookies.

关键词： wheat quality flour quality storage proteins

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Intraductal papillary bile duct adenocarcinoma and gastrointestinal stromal tumor in a case of neurofibromatosis type 1

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World Journal of Gastroenterology 2018年第4期24卷 537-542页

作者： Jung min Lee Jae min Lee Jong Jin Hyun Hyuk Soon Choi Eun Sun Kim Bora Keum Yoon Tae Jeen Hoon Jai Chun Hong sik Lee Chang Duck Kim Dong sik Kim Joo Young Kim Division of Gastroenterology and Hepatology Department of Internal Medicine Institute of Gastrointestinal Medical Instrument Research Korea University College of Medicine Division of Gastroenterology and Hepatology Department of Internal Medicine Korea University Anam Hospital Division of HBP Surgery and Liver Trans- plantation Department of Surgery Korea University College of Medicine Department of Pathology Korea University College of Medicine

We report our experience with a synchronous case of gastrointestinal stromal tumor(GIST) and intraductal papillary neoplasm of the bile duct(IPNB) in anelderly woman with neurofibromatosis type 1(NF-1). A 72-year-old woman presented with a 2-mo history of right upper abdominal pain unrelated to diet and indigestion. Fourteen years earlier, she had been diagnosed with NF-1, which manifested as café au lait spots and multiple nodules on the skin. Computed tomography(CT) revealed a multilocular low-density mass with septation, and mural nodules in the right hepatic lobe, as well as a 1.7-cm-sized well-demarcated enhancing mass in the third portion of the duodenum. The patient subsequently underwent right hepatectomy and duodenal wedge resection. We present here the first report of a case involving a synchronous IPNB and GIST in a patient with NF-1. Our findings demonstrate the possibility of various tumors in NF-1 patients and the importance of diagnosis at an early

关键词： Neurofibromatosis type 1 Intraductal papillary neoplasm of the bile duct Gastrointestinal stromal tumor Synchronous

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Foldable three dimensional neural electrode arrays for simultaneous brain interfacing of cortical surface and intracortical multilayers

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npj Flexible Electronics 2022年第1期6卷 840-853页

作者： Ju Young Lee Sang Hoon Park Yujin Kim Young Uk Cho Jaejin Park Jung-Hoon Hong Kyubeen Kim Jongwoon Shin Jeong Eun Ju In sik min mingyu Sang Hyogeun Shin Ui-Jin Jeong Yuyan Gao Bowen Li Aizhan Zhumbayeva Kyung Yeun Kim Eun-Bin Hong min-Ho Nam Hojeong Jeon Youngmee Jung Huanyu Cheng Il-Joo Cho Ki Jun Yu School of Electrical and Electronic Engineering Yonsei University50 Yonsei-roSeodaemunguSeoul 03722Republic of Korea Department of Biomedical Sciences College of MedicineKorea UniversitySeoul 02841Republic of Korea Brain Science Institute Korea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea School of Electrical Engineering Korea UniversitySeoul 02841Republic of Korea Department of Engineering Science and Mechanics The Pennsylvania State UniversityUniversity ParkPA 16802USA Center for Biomaterials Biomedical Research InstituteKorea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea Biomaterials Research Center Biomedical Research DivisionKorea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea Department of Mechanical Engineering Seoul National UniversitySeoul 08826Republic of Korea Department of Biotechnology College of Life Science and BiotechnologyYonsei UniversitySeoul 03722Republic of Korea Department of KHU-KIST Convergence Science and Technology Kyung Hee UniversitySeoul 02447Republic of Korea KU-KIST Graduate School of Converging Science and Technology Korea UniversitySeoul 02841Republic of Korea School of Electrical and Electronic Engineering YU-KIST InstituteYonsei UniversitySeoul 03722Republic of Korea Department of Materials Science and Engineering The Pennsylvania State UniversityUniversity ParkPA 16802USA Materials Research Institute The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of Anatomy College of MedicineKorea UniversitySeoul 02841Republic of Korea Department of Electrical and Electronic Engineering YU-Korea Institute of Science and Technology(KIST)InstituteYonsei University50Yonsei-roSeodaemun-guSeoul 03722Korea

Challenges in the understanding of three-dimensional(3D)brain networks by simultaneously recording both surface and intracortical areas of brain signals remain due to the difficulties of constructing mechanical design and spatial limitations of the implanted ***,we present a foldable and flexible 3D neural prosthetic that facilitates the 3D mapping of complex neural circuits with high spatiotemporal dynamics from the intracortical to cortical *** device is the tool to map the 3D neural transmission through sophisticatedly designed four flexible penetrating shanks and surface electrode arrays in one integrated *** demonstrate the potential possibilities of identifying correlations of neural activities from the intracortical area to cortical regions through continuous monitoring of electrophysiological *** also exploited the structural properties of the device to record synchronized signals of single spikes evoked by unidirectional total whisker *** platform offers opportunities to clarify unpredictable 3D neural pathways and provides a next-generation neural interface.

关键词： neural electrode simultaneous

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Characterization of transgenic mice expressing EGFP under the control of the monkey 20α-hydroxysteroid dehydrogenase promoter

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Science China(Life Sciences) 2018年第8期61卷 966-974页

作者： Chae-Won Park Seong-Keun Jeong Tsevelmaa Nanjidsuren Munkhzaya Byambaragchaa Myung-Hwa Kang Bo-Woong Sim Kwan-sik min Animal Biotechnology Graduate School of Future Convergence Technology Department of Animal Life Science Institute of Genetic Engineering Hankyong National University Department of Food Science and Nutrition Hoseo University National Primate Research Center Korea Research Institute of Bioscience and Biotechnology

To directly assess the molecular function of the monkey 20α-hydroxysteroid dehydrogenase(20α-HSD) promoter, we generated transgenic mice(tg) expressing enhanced green fluorescent protein(EGFP) under control of this promoter. We demonstrated that prostaglandin F2α induced 20α-HSD promoter activity in CHO cells in a dose-dependent manner. Furthermore, forskolin treatment markedly reduced 20α-HSD promoter activity, and prolactin exhibited weak inhibitory activity. The transgenic mouse obtained one positive founder male. The transgene was propagated in 10 successive generations without any notable defects to the progeny. EGFP and 20α-HSD in the tg mice were colocalized in the luteal cells of the ovary during late pregnancy. Strong EGFP and 20α-HSD protein signals were also detected in the adult testis. Immunohistochemical analysis revealed high EGFP levels in the seminiferous epithelium, whereas 20α-HSD was expressed in the seminiferous tubules. Our data suggest that the ovaries in monkey and mouse exhibit similar expression patterns of 20α-HSD during pregnancy. However, the expression pattern of EGFP in tg mice testis slightly differed from that of the endogenous 20α-HSD. Further investigation is required to elucidate the functional mechanisms underlying regulation of the monkey 20α-HSD promoter in the tg mice.

关键词： EGFP 转基因脱氢酶老鼠猴子控制 forskolin HSD

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Emerging Technologies of Liquid Crystal Displays

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光学学报 2003年第S1期23卷 797-798页

作者： Sin-Doo Lee Chang-Jae Yu Jae-Hong Park min-sik Jung School of Electrical Engineering #032 Seoul National University Kwanak P.O. Box 34 Seoul 151-742 KoreaSchool of Electrical Engineering #032 Seoul National University Kwanak P.O. Box 34 Seoul 151-742 KoreaSchool of Electrical Engineering #032 Seoul National University Kwanak P.O. Box 34 Seoul 151-742 KoreaSchool of Electrical Engineering #032 Seoul National University Kwanak P.O. Box 34 Seoul 151-742 Korea

The general features and the emerging technologies of liquid crystal displays are described from the viewpoints of wide viewing and fast response technologies. The device applications of liquid crystals for optical co... 详细信息

关键词： of in on it as LCD Emerging Technologies of Liquid Crystal Displays been mode DSG

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Construction of tantalum/poly(ether imide)coatings on magnesium implants with both corrosion protection and osseointegration properties

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Bioactive Materials 2021年第4期6卷 1189-1200页

作者： Kwang-Hee Cheon Cheonil Park min-Ho Kang In-Gu Kang min-Kyu Lee Hyun Lee Hyoun-Ee Kim Hyun-Do Jung Tae-sik Jang Department of Materials Science and Engineering Seoul National UniversitySeoulRepublic of Korea Department of Biomedical-Chemical Engineering Catholic University of KoreaBucheonGyeonggi-doRepublic of Korea Institute of Health Science Research Korea UniversitySeoul02841Republic of Korea Department of Materials Science and Engineering Chosun UniversityGwangjuRepublic of Korea

Poly(ether imide)(PEI)has shown satisfactory corrosion protection capability with good adhesion strength as a coating for magnesium(Mg),a potential candidate of biodegradable orthopedic implant ***,its innate hydrophobic property causes insufficient osteoblast affinity and a lack of ***,we modify the physical and chemical properties of a PEI-coated Mg implant.A plasma immersion ion implantation technique is combined with direct current(DC)magnetron sputtering to introduce biologically compatible tantalum(Ta)onto the surface of the PEI *** PEI-coating layer is not damaged during this process owing to the extremely short processing time(30 s),retaining its high corrosion protection property and adhesion *** Ta-implanted layer(roughly 10-nm-thick)on the topmost PEI surface generates long-term surface hydrophilicity and favorable surface conditions for pre-osteoblasts to adhere,proliferate,and ***,in a rabbit femur study,the Ta/PEI-coated Mg implant demonstrates significantly enhanced bone tissue affinity and osseointegration *** results indicate that Ta/PEI-coated Mg is promising for achieving early mechanical fixation and long-term success in biodegradable orthopedic implant applications.

关键词： Magnesium Tantalum Poly(ether imide) Bio-functionalized coating Biodegradable orthopedic implants

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Attribute driven inverse materials design using deep learning Bayesian framework

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npj Computational Materials 2019年第1期5卷 22-35页

作者： Piyush M.Tagade Shashishekar P.Adiga Shanthi Pandian min sik Park Krishnan S.Hariharan Subramanya Mayya Kolake Next Gen Research Samsung Advanced Institute of TechnologySamsung R&D InstituteBangalore 560037India Autonomous Material Development Lab Samsung Electronics130 Samsung-roSuwonGyeonggi-do 443-803Republic of Korea

Much of computational materials science has focused on fast and accurate forward predictions of materials properties,for example,given a molecular structure predict its electronic *** is achieved with first principles calculations and more recently through machine learning approaches,since the former is computation-intensive and not practical for high-throughput *** for the right material for any given application,though follows an inverse path—the desired properties are given and the task is to find the right *** we present a deep learning inverse prediction framework,Structure Learning for Attributedriven Materials Design Using Novel Conditional Sampling(SLAMDUNCS),for efficient and accurate prediction of molecules exhibiting target *** apply this framework to the computational design of organic molecules for three applications,organic semiconductors for thin-film transistors,small organic acceptors for solar cells and electrolyte additives with high redox *** method is general enough to be extended to inorganic compounds and represents an important step in deep learning based completely automated materials discovery.

关键词： inverse learning enough

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A combination strategy of functionalized polymer coating with Ta ion implantation for multifunctional and biodegradable vascular stents

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Journal of Magnesium and Alloys 2021年第6期9卷 2195-2207页

作者： Kwang-Hee Cheon Cheonil Park min-Ho Kang Suhyung Park Jinyoung Kim Seol-Ha Jeong Hyoun-Ee Kim Hyun-Do Jung Tae-sik Jang Department of Materials Science and Engineering Seoul National UniversitySeoul 08826Republic of Korea Department of Chemical and Biological Engineering Seoul National UniversitySeoul 08826Republic of Korea Department of Biomedical-Chemical Engineering Catholic University of KoreaBucheon-si 03083Republic of Korea Department of Biotechnology The Catholic University of KoreaBucheon-si 14662Republic of Korea Department of Materials Science and Engineering Chosun UniversityGwangju 61452Republic of Korea

Biodegradable stents made of magnesium(Mg)and its alloys have been developed to minimize persistent inflammation or in-stent restenosis,which are the main problems for permanent ***,their rapid corrosion behavior under physiological conditions leads to poor vascular compatibility and premature structural failure,which remains an important unsolved clinical ***,we demonstrate a new strategy for solving this problem by combining poly(ether imide)(PEI)coating and subsequent tantalum(Ta)ion *** PEI coating covers the whole surface of the Mg stent uniformly via a spray coating technique and provides Mg with superior corrosion resistance and stable sirolimus-carrying *** ion implantation is conducted by a sputtering-based plasma immersion ion implantation technique only onto the luminal surface of the PEI-coated Mg *** extremely short processing time(<30 s)permits preservation of the PEI coating’s corrosion protection ability and sirolimus loading *** addition,a Ta-implanted skin layer that forms on the topmost surface of the PEI coating plays an effective role in not only preventing a rapid release of sirolimus from the surface but also improving the PEI coating’s surface *** on in vitro cellular response and blood compatibility tests,Ta ion implantation leads to the improvement of endothelial cell adhesion/proliferation and suppression of platelet adhesion/activation regardless of sirolimus *** results indicate that the combination of PEI coating and Ta ion implantation has significant innovative potential to provide excellent vascular compatibility and prevent in-stent restenosis and thrombosis.

关键词： Magnesium stent Biodegradability Tantalum Plasma immersion ion implantation Multifunctionality

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