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World Journal of Gastroenterology 2005年第6期11卷 810-816页

作者： Jae-Sung Bae kwang-ho Jang Hee-Kyung Jin Department of Surgery Department of Laboratory Animal Medicine

AIM: To assess the adhesion- and abscess-reducing capacities of various concentrations of polysaccharides derived from fungus, Phellinus gilvus (PG) or Phellinus linteus (PL) in a rat peritonitis ***: In 96 SD rats, experimental peritonitis was induced using the cecal ligation and puncture model (CLP).Rats were randomly assigned to 8 groups; Ringer's lactate solution (RL group), hyaluronic acid (HA group), 0.025%,0.25%, and 0.5% polysaccharides from PG (PG0.025, 0.25,and 0.5 groups), and PL (PL0.025, 0.25, and 0.5 groups).Adhesions and abscesses were noted at 7 d after ***-PCR assay was performed to assess the cecal ***: Adhesion formation was significantly reduced in PG0.25, 0.5, PL0.25, 0.5, and HA groups (2.5±0.7,2.4±0.7, 3.8±1.0, 3.6±0.8, and 2.7±1.1, P＜0.05). The incidence of abscesses was significantly reduced in all treated groups compared to RL group (58%, P＜0.05). The urokinase-type plasminogen activator (uPA) gene expression was greatly up-regulated by increasing the concentration of polysaccharides. The urokinase-type plasminogen activator receptor (uPAR) and tumor necrosis factor (TNF)-α mRNA were highly expressed in PG0.25, 0.5, PL0.25, and ***: We concluded that 0.5% polysaccharide derived from PG and PL was the optimal concentration in preventing adhesion and abscess formation and may act by modulating activity of uPA and TNF-α in a rat peritonitis model.

关键词： Adhesion Abscess Phellinus gilvus, Phellinus linteus Polysaccharides

Development of High-Pressure Multigrain X-Ray Diffraction for Exploring the Earth’s Interior

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Engineering 2019年第3期5卷 441-447页

作者： Li Zhang hongsheng Yuan Yue Meng ho-kwang Mao Center for High Pressure Science and Technology Advanced Research (HPSTAR) Shanghai 201203 China HPCAT X-Ray Science Division Argonne National Laboratory Argonne IL 60439 USA Geophysical Laboratory Carnegie Institution of Washington Washington DC 20015 USA

The lower mantle makes up more than a half of our planet’s volume. Mineralogical and petrological experiments on realistic bulk compositions under high pressure–temperature (P–T) conditions are essential for understanding deep mantle processes. Such high P–T experiments are commonly conducted in a laser-heated diamond anvil cell, producing a multiphase assemblage consisting of 100 nm to submicron crystallite grains. The structures of these lower mantle phases often cannot be preserved upon pressure quenching;thus, in situ characterization is needed. The X-ray diffraction (XRD) pattern of such a multiphase assemblage usually displays a mixture of diffraction spots and rings as a result of the coarse grain size relative to the small X-ray beam size (3–5 lm) available at the synchrotron facilities. Severe peak overlapping from multiple phases renders the powder XRD method inadequate for indexing new phases and minor phases. Consequently, structure determination of new phases in a high P–T multiphase assemblage has been extremely difficult using conventional XRD techniques. Our recent development of multigrain XRD in high-pressure research has enabled the indexation of hundreds of individual crystallite grains simultaneously through the determination of crystallographic orientations for these individual grains. Once indexation is achieved, each grain can be treated as a single crystal. The combined crystallographic information from individual grains can be used to determine the crystal structures of new phases and minor phases simultaneously in a multiphase system. With this new development, we have opened up a new area of crystallography under the high P–T conditions of the deep lower mantle. This paper explains key challenges in studying multiphase systems and demonstrates the unique capabilities of high-pressure multigrain XRD through successful examples of its applications.

关键词： High pressure Synchrotron X-ray Multigrain Diamond anvil cell Minerals Petrology Earth’s interior

A Continuous Current Model of Accumulation Mode(Junctionless)Cylindrical Surrounding-Gate Nanowire MOSFETs

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Chinese Physics Letters 2013年第3期30卷 190-193页

作者： JIN Xiao-Shi LIU Xi kwon Hyuck-In LEE Jong-ho School of Information Science and Engineering Shenyang University of TechnologyShenyang 110023 School of Electrical and Electronics Engineering Chung-Ang UniversitySeoul 156-756Korea School of EECS Engineering and ISRC(Inter-University Semiconductor Research Center) Seoul National UniversityShinlim-DongKwanak-GuSeoul 151-742Korea

A continuous current model of accumulation mode or so-called junctionless(JL)cylindrical surrounding-gate Si Nanowire metal-oxide-silicon field effect transistors(MOSFETs)is *** model is based on an approximated solution of Poisson's equation considering both body doping and mobile charge *** is verified by comparing with three-dimensional simulation results using SILVACO Atlas TCAD which shows good *** any empirical fitting parameters,the proposed continuous current model of JL SRG MOSFETs is valid for all the operation regions.

关键词： MOSFETs TCAD cylindrical

Central post-stroke pain due to injury of the medial lemniscus in a patient with medullary infarction

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Neural Regeneration Research 2021年第7期16卷 1351-1352页

作者： Sung ho Jang Hyeok Gyu kwon Department of Physical Medicine and Rehabilitation College of MedicineYeungnam UniversityDaeguRepublic of Korea Department of Physical Therapy College of Health ScienceEulji UniversitySeongnamRepublic of Korea

Central post-stroke pain(CPSP), which is neuropathic pain associated with a brain lesion following a stroke, was first described by Dejerine and Roussy in 1906 in a thalamic infarct patient(Dejerine and Roussy, 1906;W... 详细信息

关键词： pain patient medial

Estimation of exposure dose for decontamination workers from contaminated soil at a nuclear decommissioning site in Korea

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辐射防护 2020年第6期40卷 619-624页

作者： Sohyeon Lee Dong-kwon Keum Hyo-Joon Jeong In Jun kwang-Muk Lim and Yong-ho Choi Korea Atomic Energy Research Institute 989-111 Daedeok-daeroYuseong-guDaejeonRepublic of Korea

Assessment of the exposure dose for workers is crucial to protecting workers from the radiological *** preliminary study estimates the potential radiological exposure for a soil remediation worker at a nuclear decommissioning site contaminated with Cs-137 in Korea,and then calculates the maximum workable soil concentration to comply with the occupational dose constraint of 20 mSv per *** Korean characteristic data,detailed exposure scenarios for workers by the type of work,and relevant exposure pathways were used in the dose *** a result,the most severe exposure-induced work type was identified as the excavator operation with an annual individual dose of 5.92×10^-5 mSv for a unit concentration of soil,from which the derived maximum workable soil concentration was 3.38×105 Bq/***,dose contribution by each exposure pathway was found to be decreased in the following order:external radiation exposure,soil ingestion,dust inhalation,and skin *** results of this study are expected to be used effectively to optimize radiation protection for workers and establish appropriate work procedures for future site remediation.

关键词： nuclear decommissioning decontamination site remediation dose assessment radiological risk radiological environmental impact assessment radiation protection

Feasible economic strategies to improve screening compliance for colorectal cancer in Korea

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World Journal of Gastroenterology 2005年第11期11卷 1587-1593页

作者： Sang Min Park Young ho Yun Soonman kwon Department of Family Medicine Quality of Cancer Care Branch School of Public Health

ABM: While colorectal cancer (CRC) is an ideal target for population screening, physician and patient attitudes contribute to low levels of screening uptake. This study was carried out to find feasible economic strategies to improve the CRC screening compliance in Korea. METhoDS: The natural history of a simulated cohort of 50-year-old Korean in the general population was modeled with CRC screening until the age of 80 years. Cases of positive results were worked up with colonoscopy. After polypectomy, colonoscopy was repeated every 3 years. Baseline screening compliance without insurance coverage by the national health insurance (NHI) was assumed to be 30%. If NHI covered the CRC screening or the reimbursement of screening to physicians increased, the compliance was assumed to increase. We evaluated 16 different CRC screening strategies based on Markov model. RESULTS: When the NHI did not cover the screening and compliance was 30%, non-dominated strategies were colonoscopy every 5 years (COL5) and colonoscopy every 3 years (COL3). In all scenarios of various compliance rates with raised coverage of the NHI and increased reimbursement of colonoscopy, COL10, COL5 and COL3 were non-dominated strategies, and COL10 had lower or minimal incremental medical cost and financial burden on the NHI than the strategy of no screening. These results were stable with sensitivity analyses. CONCLUSION: Economic strategies for promoting screening compliance can be accompanied by expanding insurance coverage by the NHI and by increasing reimbursement for CRC screening to providers. COL10 was a cost-effective and cost saving screening strategy for CRC in Korea.

关键词： Cost-effectiveness analysis Colorectal cancer Screening Compliance National health insurance Coverage Reimbursement

On the factors of Bitcoin’s value at risk

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Financial Innovation 2021年第1期7卷 1855-1885页

作者： Ji ho kwon College of Business Gachon University1342 Seongnam‑daeroSujeong‑guSeongnam‑siGyeonggi‑doRepublic of Korea

This study investigates the factors of Bitcoin’s tail risk,quantified by Value at Risk(VaR).Extending the conditional autoregressive VaR model proposed by Engle and Manganelli(2004),I examine 30 potential drivers of Bitcoin’s 5%and 1%*** the 5%VaR,quantity variables,such as Bitcoin trading volume and monetary policy rate,were positively significant,but these effects were attenuated when new samples were *** 5%VaR responds positively to the Internet search index and negatively to the fluctuation of returns on commodity variables and the Chinese stock market *** the 1%VaR,variables related to the macroeconomy play a key *** consumer sentiment index exerts a strong positive effect on the 1%VaR.I also find that the 1%VaR has positive relationships with the US economic policy uncertainty index and the fluctuation of returns on the corporate bond index.

关键词： Bitcoin Value at risk CAViaR

Xieite,a new mineral of high-pressure FeCr_2O_4 polymorph

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Chinese Science Bulletin 2008年第21期53卷 3341-3345页

作者： CHEN Ming SHU JinFu MAO ho-kwang Guangzhou Institute of Geochemistry Chinese Academy of Sciences Guangzhou 510640 China Geophysical Laboratory Carnegie Institution of Washington 5251 Broad Branch Road NW 20015 Washington DC USA

Xieite,a new mineral,occurs in the shock vein of the Suizhou *** mineral has an ortho-rhombic structure and its space group is *** cell parameters are a = 9.462(6),b = 9.562(9),c = 2.916(1).The crystal-chemical formula is(Fe0.87Mg0.13Mn0.01)1.01(Cr1.62Al0.25Ti0.08V0.02)1.97O4,or simply formula *** X-ray diffraction lines are [d(),I/Io]:(2.675,100),(2.389,20),(2.089,10),(1.953,90),(1.566,60),(1.439,15),(1.425,15),(1.337,40).Xieite is a high pressure polymorph of FeCr2O4 and formed by solid-state transformation of chromite under shock-induced high pressure and tem-perature,in association with other high-pressure minerals including ringwoodite,majorite,lingunite and *** P-T condition for the formation of xieite is estimated to be 18―23 GPa and 1800―1950℃,*** has recently been approved by the Commission on New Minerals,Nomenclature and Classification of the International Mineralogical Association(IMA 2007-056).The mineral name,xieite,is named after Xiande Xie.

关键词：络铁矿高压环境基因多态性矿物

Injury of the Papez circuit in a patient with traumatic spinal cord injury and concomitant mild traumatic brain injury

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Neural Regeneration Research 2018年第1期13卷 161-162页

作者： Sung ho Jang Hyeok Gyu kwon Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Department of Physical Therapy College of Health Sciences Catholic University of Pusan

Little is known about brain injury in concomitant mild traumatic brain injury （TBI） following traumatic spinal cord injury （TSCI）. In this study, we reported on a male patient with memory impairment who showed inj... 详细信息

关键词： DIFFUSION TENSOR TRACTOGRAPHY MEMORY TRACT

Delayed degeneration of an injured spinothalamic tract in a patient with diffuse axonal injury

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Neural Regeneration Research 2017年第11期12卷 1927-1928页

作者： Sung ho Jang Hyeok Gyu kwon Department of Physical Medicine and Rehabilitation College of MedicineYeungnam UniversityDaemyungdongNamkuDaeguRepublic of Korea Department of Physical Therapy College of Health SciencesCatholic University of PusanPusanRepublic of Korea

Diffuse axonal injury （DAI） is one of the devastating mechanisms of traumatic brain injury （TBI） and shows extensive sub- cortical lesions due to shearing forces induced by rapid acceleration-deceleration and rotation of the brain （Adams et al., 1982; Meythaler et al., 2001）. As a result, conventional brain imaging techniques including brain MRI have been limited in demon- strating neuronal degeneration in patients with DAI. however, diffusion tensor tractography （DTT）, which is derived from diffusion tensor imaging （DTI） has enabled three-dimensional reconstruction of the neural tracts （Jang and Seo, 2014）. Since the introduction of DTI, several studies have demonstrated neuronal degeneration after TBI （Tomaiuolo et al., 2005; hong and lang, 2010; kwon and Jang, 2014）. however, little is known about delayed neuronal degeneration in patients with TBI.

关键词： Delayed degeneration of an injured spinothalamic tract patient