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远侧脾-肾分流术与经颈静脉肝内门体分流术治疗静脉曲张破裂出血:一项随机研究

世界核心医学期刊文摘（胃肠病学分册） 2006年第10期2卷 29-30页

作者： Henderson J.m. Boyer T.D. kutner m.H. 纪泛扑 Department of Surgery Cleveland ClinicClevelandOHUnited States

Background &Aims: Variceal bleeding refractory to medical treatment with β-blockers and endoscopic therapy can be managed by variceal decompression with either surgical shunts or transjugular intrahepatic portal systemic shunts (TIPS). This prospective randomized trial tested the hypothesis that patients receiving distal splenorenal shunts (DSRS) would have significantly lower rebleeding and encephalopathy rates than TIPS in management of refractory variceal bleeding. methods: A prospective randomized controlled clinical trial at 5 centers was conducted. One hundred forty patients with Child-Pugh class A and B cirrhosis and refractory variceal bleeding were randomized to DSRS or TIPS. Protocol and event follow-up for 2-8 years (mean, 46 ±26 months) for primary end points of variceal bleeding and encephalopathy and secondary end points of death, ascites, thrombosis and stenosis, liver function, need for transplant, quality of life, and cost were evaluated. Results: There was no significant difference in rebleeding (DSRS, 5.5%; TIPS, 10.5%; P = .29) or first encephalopathy event (DSRS, 50%; TIPS, 50%). Survival at 2 and 5 years (DSRS, 81%and 62%; TIPS, 88%and 61%, respectively) were not significantly different (P = .87). Thrombosis, stenosis, and reintervention rates (DSRS, 11%; TIPS, 82%) were significantly (P milarly efficacious in the control of refractory variceal bleeding in Child-Pugh class A and B patients. Reintervention is significantly greater for TIPS compared with DSRS. Because both procedures have equivalent outcomes, the choice is dependent on available expertise and ability to monitor the shunt and reintervene when needed.

关键词：静脉曲张破裂分流术经颈静脉肝内门 TIPS 随机研究肝移植 β-阻滞剂肝性脑病次要终点血

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端粒缩短,再生能力与心血管预后

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中华高血压杂志 2016年第12期24卷 1174-1174页

作者：刘莉叶鹏 Hammadah m mheid IA Wilmot K Ramadan R Abdulhadi N Alkhoder A Obideen m Pimple P Levantsevych O Kelli H Shah A Sun Y Pearce B kutner m Long Q Ward L Ko YA mohammed KH Lin J Zhao J Bremner J Kim J Waller E Raggi P Sheps D Quyyumi A Vaccarino V

白细胞端粒长度（leucocyte telomere length,LTL）是衰老的生物标志物,较短的LTL与不良的心血管预后相关。端粒再生能力降低可能是其机制之一。骨髓来源的循环祖细胞（progenitor cells,PCs）参与组织修复和再生。该研究的目的是研究LT... 详细信息

白细胞端粒长度（leucocyte telomere length,LTL）是衰老的生物标志物,较短的LTL与不良的心血管预后相关。端粒再生能力降低可能是其机制之一。骨髓来源的循环祖细胞（progenitor cells,PCs）参与组织修复和再生。该研究的目的是研究LTL与PCs之间的关系及其对不良心血管预后的影响。方法：通过定量聚合酶链反应测定566例冠状动脉疾病（coronary artery disease, CAD）门诊患者[年龄（63±9）岁，76％为男性]的LTL。

关键词：端粒 telomere leucocyte 骨髓来源 progenitor 生物标志物祖细胞组织修复 length 四分位数

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天文学物理新视野 a physical perspective

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2005年

作者：（美）m. L. 库特纳（marc L. kutner）萧耐园胡方浩译

本书是一本综合介绍天体和天文现象的书。它从一些最基本的天体出发，透彻地解释了天文现象如何发生，为什么发生，天文学家如何收集关于恒星、星系和太阳系的信息，并如何解释这些信息等。

ISBN: (数字)7535744168

ISBN: (纸本)7535744168

关键词：天文学学科:基本知识

来源：汇雅图书（南通市图书馆... 评论

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Gait speed and hospitalization among ambulatory hemodialysis patients: USRDS special study data

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World Journal of Nephrology 2014年第3期3卷 101-106页

作者： Nancy G kutner Rebecca Zhang Yijian Huang Haimanot Wasse USRDS Rehabilitation/Quality of Life Special Studies Center Emory University Atlanta GA 30322 United States Renal Division Department of Medicine and USRDS Rehabilitation/Quality of Life Special Studies Center Emory University Atlanta GA30322 United States

AIm:To assess the association of measured gait speed with hemodialysis(HD)patients’hospitalization,in conjunction with,and apart from,recent fall ***:Gait speed was measured by a standard protocol and falls during the past 12 mo were ascertained for a prevalent multi-center HD cohort(n=668)aged *** during the past 12 mo was identified in the patient’s clinic records,and the first hospitalization after gait speed assessment(or the competing event of death)was identified in the 2013 United States Renal Data System Standard Analysis ***:Slow gait speed,defined asm/s,characterized 34.7%of the patients,and 27.1%had experienced a recent *** with slow gait speed but without a history of recent falls were 1.79 times more likely to have been hospitalized during the past12 mo(OR=1.79,95%CI:1.11-2.88,P=0.02),and patients with slow gait speed and a history of recent falls were over two times more likely to have been hospitalized(OR=2.10,95%CI:1.19-3.73,P=0.01),compared with patients having faster gait speed and no recent fall *** examination of gait speed/fall history status in relation to first hospitalization(or death)incurred by the end of follow-up December 31,2011 also showed that slow gait speed was associated with these events in conjunction with a history of falls(HR=1.54,95%CI:1.04-2.30,P=0.03).CONCLUSION:The International Task Force on Nutrition and Aging reported that gait speed is a powerful predictor for older adults of adverse outcomes such as *** our data,gait speed--apart from,as well as in conjunction with,recent fall history--was associated with HD patients’hospitalization for multiple *** speed may be a sensitive health indicator among HD patients across the age spectrum.

关键词：步态速度老年人肾病治疗方法

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