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Gra.hene oxide-lithium-ion ba.teries: ina.gura.ion of a. era.in energy stora.e technology

CLEa. ENERGY 2024年第3期8卷 194-205页

作者： Mishra. Ya.ha.a.Cha.ta.a., a.iti a.ja.a.i, a.a. a. a. El-Ta.a.i, Moha.ed Ta.buwa.a. Murta.a.M. Mishra. Vija. Lovely Profess Univ Sch Bioengn & Biosci Phagwara 144411 Punjab India Ya.mouk Univ Dept Pharmaceut & Pharmaceut Technol Irbid Jordan Ra. a. Kha.ma. Med & Hlth Sci Univ Coll Pharm Ras Al Khaymah U Arab Emirates Univ Lincoln Lincoln Med Sch Brayford Pool Campus Lincoln LN6 7TS England Lovely Profess Univ Sch Pharmaceut Sci Phagwara 144411 Punjab India

a.significa.t driving force behind the brisk resea.ch on recha.gea.le ba.teries, pa.ticula.ly lithium-ion ba.teries (LiBs) in high-performa.ce a.plica.ions, is the development of porta.le devices a.d electric vehicles. Ca.bon-ba.ed ma.eria.s, which ha.e finite specific ca.a.ity, ma.e up the a.odes of LiBs. Ma.y a.tempts a.e being ma.e to produce novel na.ostructured composite a.ode ma.eria.s for LiBs tha. displa. cycle sta.ility tha. is superior to tha. of gra.hite using gra.hene oxide. Therefore, using significa.t a.ounts of wa.te gra.hene oxide from used LiBs represents a.fa.ta.tic opportunity to enga.e in wa.te ma.a.ement a.d circula. economy. This review outlines recent studies, developments a.d the current a.va.cement of gra.hene oxide-ba.ed LiBs, including prepa.a.ion of gra.hene oxide a.d utiliza.ion in LiBs, pa.ticula.ly from the perspective of energy stora.e technology, which ha. dra.n more a.d more a.tention to crea.ing high-performa.ce electrode systems. Recent studies, developments a.d the current a.va.cement of gra.hene oxide-ba.ed lithium-ion ba.teries a.e reviewed, including prepa.a.ion of gra.hene oxide a.d utiliza.ion in lithium-ion ba.teries, pa.ticula.ly from the perspective of energy stora.e technology, which ha. dra.n a.tention to crea.ing high-performa.ce electrode systems. Gra.hica. a.stra.t

关键词： lithium-ion ba.teries gra.hene oxide energy stora.e technology wa.te ma.a.ement clea. energy ELECTROCHEMICa. PERFORMa.CE Ca.HODE Na.OPa.TICLES ELECTROLYTES EFFICIENCY CELLS

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Eleva.ed ca.diova.cula. risk a.d a.ute events in hospita.ized colon ca.cer survivors:a.deca.e-a.a.t study of two na.ionwide cohorts

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World Journa. of Clinica. Oncology 2024年第4期15卷 548-553页

作者： Rupa. Desa. a.ila.h Monda. Vivek patel Sa.deep Singh Sha.lika.Cha.ha. a.hil Ja.n Independent Resea.cher AtlantaGA 30079United States Depa.tment of Interna. Medicine Nazareth HospitalPhiladelphiaPA 19152United States Depa.tment of Clinica. Epidemiology Biostatistics and Bio-informaticsAmsterdam UMCAmsterdam 7057Netherlands Depa.tment of Interna. Medicine Geisinger Health SystemWikes-BarrePA 18702United States Division of Leukemia The University of Texas MD Anderson Cancer CenterHoustonTX 77079United States

Ba.KGROUND Over the yea.s,strides in colon ca.cer detection a.d trea.ment ha.e boosted surviva. ra.es;yet,post-colon ca.cer surviva. enta.ls ca.diova.cula. disea.e(CVD)*** on CVD risks a.d a.ute ca.diova.cula. events in colorecta. ca.cer survivors ha. been *** To compa.e the CVD risk a.d a.verse ca.diova.cula. outcomes in current colon ca.cer survivors compa.ed to a.deca.e *** We a.a.yzed 2007 a.d 2017 hospita.iza.ion da.a.from the Na.iona. Inpa.ient Sa.ple,studying two colon ca.cer survivor groups for CVD risk fa.tors,morta.ity ra.es,a.d ma.or a.verse events like pulmona.y embolism,a.rhythmia.ca.dia. a.rest,a.d stroke,a.justing for confounders via.multiva.ia.le regression *** Of tota. colon ca.cer survivors hospita.ized in 2007(n=177542)a.d 2017(n=178325),the 2017 cohort often consisted of younger(76 vs 77 yea.s),ma.e,a.rica.-a.erica.,a.d Hispa.ic pa.ients a.mitted non-electively vs the 2007 ***,the 2017 cohort ha. higher ra.es of smoking,a.cohol a.use,drug a.use,coa.ulopa.hy,liver disea.e,weight loss,a.d rena. *** in the 2017 cohort a.so ha. higher ra.es of ca.diova.cula. comorbidities,including hypertension,hyperlipidemia.dia.etes,obesity,periphera. va.cula. disea.e,congestive hea.t fa.lure,a.d a. lea.t one tra.itiona. CVD(Pa.justed multiva.ia.le a.a.ysis,the 2017 cohort ha. a.significa.tly higher risk of pulmona.y embolism(PE)(OR:1.47,95%CI:1.37-1.48),a.rhythmia.OR:1.41,95%CI:1.38-1.43),a.ria. fibrilla.ion/flutter(OR:1.61,95%CI:1.58-1.64),ca.dia. a.rest including ventricula. ta.hya.rhythmia.OR:1.63,95%CI:1.46-1.82),a.d stroke(OR:1.28,95%CI:1.22-1.34)with compa.a.le a.l-ca.se morta.ity a.d fewer routine discha.ges(48.4%vs 55.0%)(Pa.cer survivors hospita.ized 10 yea.s a.a.t in the United Sta.es showed a. increa.ed CVD risk with a. increa.ed risk of a.ute ca.diova.cula. events(stroke 28%,PE 47%,a.rhythmia.41%,a.d ca.dia. a.res

关键词： Colon ca.cer Colorecta. ca.cer Ca.diova.cula. disea.es Ca.diova.cula. disea.e risk Ca.dia. events Stroke

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透明质酸填充剂HYC-24/HYC-24+治疗中国中、重度鼻唇沟皱褶患者满意度的真实世界研究

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中华整形外科杂志 2024年第4期40卷 436-443页

作者：曹令宋为民徐士亮隋志甫 Joy Ma.la.ba.a. Va.sha.i patel 北京丽都医疗美容医院整形外科北京100101 杭州颜术悦容医疗美容诊所美容皮肤科杭州州310008 广州粤秀整形外科医院整形外科广州1510600 a.lerga. a.sthetics(艾伯维旗下公司) 新加坡117439 a.lerga.a.sthetics(艾伯维旗下公司) 美国加利福尼亚州尔湾市92612

目的评估中国中度至重度鼻唇沟皱褶(NLF)患者在真实的临床实践环境中接受HYC-24/HYC-24+治疗后的结局满意度。方法本研究是一项前瞻性、观察性、多中心、真实世界队列研究。纳入2018年8月至2020年8月于北京丽都医疗美容医院、杭州颜术... 详细信息

目的评估中国中度至重度鼻唇沟皱褶(NLF)患者在真实的临床实践环境中接受HYC-24/HYC-24+治疗后的结局满意度。方法本研究是一项前瞻性、观察性、多中心、真实世界队列研究。纳入2018年8月至2020年8月于北京丽都医疗美容医院、杭州颜术悦容医疗美容诊所和广州粤秀整形外科医院接受HYC-24/HYC-24+治疗,并随访长达1年的中国患者,年龄18至65岁、患有中度至重度NLF,且在研究入组前6个月内未接受过NLF的美容治疗。在第1、6、9和12个月进行治疗后研究访视,仅第6个月和第9个月为必须进行的访视。患者报告结局的主要终点包括:Fa.E-Q结局满意度问卷总分(评分范围为0~100分,分数越高表示结局越好,患者越满意),Fa.E-Q皱纹评估-NLF问卷总分较基线的平均变化(评分范围为0~100分,评分越高表示患者在过去1周内越不受到NLF的困扰),以及在Fa.E-Q患者感知年龄视觉模拟评分法(Va.)上报告比实际年龄看起来更年轻的患者比例。研究者评估终点包括整体美容效果改善量表(Ga.S)评分≥1分的患者比例,以及使用鼻唇沟皱褶严重程度量表(NLFSS)评估NLF严重程度改善≥1分的患者比例。使用Sa. 9.4软件进行统计分析,计量资料采用±s表示,计数资料用例数(%)表示,不同访视时间与基线的比较,采用Wilcoxon符号秩检验。结果共52例患者入组并接受治疗,其中,7例因访视时间超出访视评估窗而未被纳入第6个月有效性的分析数据集,仅9例患者完成了第12个月的访视。所有患者均为中国籍女性,年龄26~62岁,平均为40.7岁。Fa.E-Q结局满意度问卷总分第6个月时为(68.76±21.03)分(38~100分),第9个月时为(65.44±18.24)分(24~100分),表明患者对治疗的满意度较高。Fa.E-Q皱纹评估-NLF问卷总分基线时为(42.4±15.1)分(10~69分),第6个月时为(76.9±20.6)分(36~100分),第9个月时为(74.2±16.7)分(36~100分),均较基线得分明显升高(P均a.E-Q患者感知年龄Va.报告认为比实际年龄看起来更年轻的患者比例从基线时的28.9%(15/52)分别增加到第6个月的77.8%(35/45)和第9个月的73.1%(38/52),与基线相比,差异均有统计学意义(Pa.S量表得分改善均≥1分,表明研究者认为患者NLF外观均有所改善。在NLFSS评价方面,分别有97.8%(44/45)和82.7%(43/52)的患者在第6个月和第9个月的NLFSS改善程度≥1分。试验期间无不良事件报告。结论在真实临床实践环境中,对中国患者施用HYC-24/HYC-24+后,使用经验证的问卷调查显示,患者对结局表示满意。患者还报告称治疗后看起来比实际年龄年轻,并且受NLF的困扰较少。临床医生报告结局与患者报告结局一致,表明NLF有所改善。

关键词：鼻唇沟,鼻唇褶透明质酸患者满意度亚裔整形手术

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Preopera.ive serum cortisone levels a.e a.socia.ed with cognition in preschool‑a.ed children with tetra.ogy of Fa.lot a.ter corrective surgery:new evidence from huma. popula.ions a.d mice

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World Journa. of Pedia.rics 2024年第2期20卷 173-184页

作者： Si-Yu Ma.Yu-Ting Liu Yue-Shua.g Cun Qia.g Wa.g Ming-Cui Fu Ke-De Wu Xin-Yu Ca. Shu-Ting Cheng Nisha.t patel Min Da.Lia.g Hu Zhuoga.Deqin Xue-Jun Ka.g Ming Ya.g Xu-Ming Mo Depa.tment of Ca.diothora.ic Surgery Children’s Hospital of Nanjing Medical University72 Guangzhou RoadNanjing 210008China Depa.tment of Ra.iology Children’s Hospital of Nanjing Medical University72 Guangzhou RoadNanjing 210008China Key La.ora.ory of Child Development a.d Lea.ning Science Research Center For Learning ScienceSchool of Biological Sciences&Medical EngineeringMinistry of EducationSoutheast UniversityNanjing 210096China Medica. School of Na.jing University Nanjing 210093China

Ba.kground Tetra.ogy of Fa.lot(TOF)is the most common cya.otic congenita. hea.t *** with TOF would be confronted with neurologica. impa.rment a.ross their *** study a.med to identify the risk fa.tors for cerebra. morphology cha.ges a.d cognition in postopera.ive preschool-a.ed children with *** We used ma.s spectrometry(MS)technology to a.sess the levels of serum meta.olites,Wechsler preschool a.d prima.y sca.e of intelligence-Fourth edition(WPPSI-Ⅳ)index scores to eva.ua.e neurodevelopmenta. levels a.d multimoda. ma.netic resona.ce ima.ing(MRI)to detect cortica. morphologica. *** Multiple linea. regression showed tha. preopera.ive levels of serum cortisone were positively correla.ed with the gyrifica.ion index of the left inferior pa.ieta. gyrus in children with TOF a.d nega.ively rela.ed to their lower visua. spa.es index a.d nonverba. ***,preopera.ive SpO_(2) wa. nega.ively correla.ed with levels of serum cortisone a.ter a.justing for a.l ***,a.ter intervening levels of cortisone in chronic hypoxic model mice,tota. bra.n volumes were reduced a. both postna.a.(P)11.5 a.d P30 *** Our results suggest tha. preopera.ive serum cortisone levels could be used a. a.bioma.ker of neurodevelopmenta. impa.rment in children with *** study findings empha.ized tha. preopera.ive levels of cortisone could influence cerebra. development a.d cognition a.ilities in children with TOF.

关键词： Cognition Cortisone MRI Neurodevelopment Tetra.ogy of Fa.lot

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海藻养殖场助力碳捕捉行业发展

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科技纵览 2024年第1期 40-41页

作者： Pra.hi patel 不详

2023年1月,研究人员首次在菲律宾宿务市附近的水域部署了一个撒有海藻种子的巨大环状网,并用辐条状的绳索和管子将其支撑展开。每天傍晚,安装在浮动平台上的曲柄会将网拉到水面以下25米,让海藻暴露在更凉爽、营养更丰富的水中。黎明时,... 详细信息

2023年1月,研究人员首次在菲律宾宿务市附近的水域部署了一个撒有海藻种子的巨大环状网,并用辐条状的绳索和管子将其支撑展开。每天傍晚,安装在浮动平台上的曲柄会将网拉到水面以下25米,让海藻暴露在更凉爽、营养更丰富的水中。黎明时,曲柄会将网拉回水面,吸收阳光和二氧化碳。

关键词：浮动平台环状网二氧化碳碳捕捉海藻助力曲柄养殖场

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提取锂的方法将更快、更加环保

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科技纵览 2024年第1期 7-9页

作者： Pra.hi patel 不详

安第斯山脉位于阿根廷、玻利维亚和智利的边界,这里浩瀚的白色盐沼绵延数千公里,下面的盐水蕴藏的锂占全球总量的58%。几十年来,生产商提取锂的方法一直是将水抽取到地面并使其蒸发提纯,直至可滤出锂盐。该过程需要12到18个月,会留下成... 详细信息

安第斯山脉位于阿根廷、玻利维亚和智利的边界,这里浩瀚的白色盐沼绵延数千公里,下面的盐水蕴藏的锂占全球总量的58%。几十年来,生产商提取锂的方法一直是将水抽取到地面并使其蒸发提纯,直至可滤出锂盐。该过程需要12到18个月,会留下成堆的含有其他金属的废弃物,此外还会蒸发近200万升当地的水资源,给本土社区带来危害。

关键词：玻利维亚废弃物水资源阿根廷锂生产商

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Lea. body ma.s index is a.ma.ker of a.va.ced tumor fea.ures in pa.ients with hepa.ocellula. ca.cinoma

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World Journa. of Hepa.ology 2024年第3期16卷 393-404页

作者： a.drew Scott deLemos Jing Zha. Milin patel Ba.ks Kooken Ka.a. Ma.hur Hieu Minh Nguyen a.eej Ma.ha. Ma.gie McCa.ter Hea.her Burney Ca.la.Kettler Na.a.Cha.a.a.i Sa.er Ga.rieh Depa.tment of Medicine Atrium HealthCharlotteNC 28204United States Center for Outcomes Resea.ch a.d Eva.ua.ion Atrium HealthCharlotteNC 28204United States Depa.tment of Medicine Indiana University School of MedicineIndianapolisIN 46202United States Center for Hea.th System Sciences(CHa.SIS) Atrium HealthCharlotteNC 28204United States Depa.tment of Medicine Northwestern University Feinberg School of MedicineChicagoIL 60611United States Depa.tment of Biosta.istics a.d Hea.th Da.a.Science Indiana University School of MedicineIndianapolisIN 46202United States Depa.tment of Ga.troenterology a.d Hepa.ology Indiana University School of MedicineIndianapolisIN 46202United States

Ba.KGROUND Obesity is a. independent risk fa.tor for the development of hepa.ocellula. ca.cinoma.HCC)a.d ma. influence its ***,a.ter dia.nosis of HCC,like other ma.igna.cies,the obesity pa.a.ox ma. exist where higher body ma.s index(BMI)ma. in fa.t confer a.surviva. *** is frequently observed in pa.ients with a.va.ced HCC a.d cirrhosis,who often present la.e with a.va.ced tumor fea.ures a.d ca.cer rela.ed weight *** To explore the rela.ionship between BMI a.d surviva. in pa.ients with cirrhosis a.d *** This is a.retrospective cohort study of over 2500 pa.ients dia.nosed with HCC between 2009-2019 a. two United Sta.es a.a.emic medica. *** a.d tumor cha.a.teristics were extra.ted ma.ua.ly from medica. records of ea.h institutions'ca.cer *** were stra.ified a.cording to BMI cla.ses:a.),25-29.9 kg/m^(2)(overweight),a.d>30 kg/m^(2)(obese).Pa.ient a.d tumor cha.a.teristics were compa.ed a.cording to BMI *** performed a. overa.l surviva. a.a.ysis using Ka.la. Meier by the three BMI cla.ses a.d a.ter a.justing for Mila. criteria.a.multiva.ia.le Cox regression model wa. then used to a.sess known risk fa.tors for surviva. in pa.ients with cirrhosis a.d *** a.tota. of 2548 pa.ients with HCC were included in the a.a.ysis of which 11.2%(n=286)were cla.sified a. *** three ma.n BMI ca.egories:Lea.(n=754),overweight(n=861),a.d obese(n=933)represented 29.6%,33.8%,a.d 36.6%of the tota. popula.ion *** ea.h BMI cla.s,the non-cirrhotic pa.ients a.counted for 15%(n=100),12%(n=94),a.d 11%(n=92),*** pa.ients with a.BMIa. *** the obese cohort,42%(n=396)ha. a.BMI≥35 kg/m^(2).Out of 2262 pa.ients with cirrhosis a.d HCC,654(29%)were lea.,767(34%)were overweight,a.d 841(37%)were *** three BMI cla.ses did not differ by a.e,MELD,or Child-Pugh *** hepa.itis C wa. the domina.t etiology in lea

关键词： Hepa.ocellula. ca.cinoma Cirrhosis Obesity Body ma.s index cla.s Sa.copenia Chronic hepa.itis C

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生成式人工智能“瘦身”,进入便携消费电子产品

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科技纵览 2024年第2期 7-9页

作者： Pra.hi patel 不详

消费电子产品技术瞄准各种大型语言模型,笔记本电脑是滩头阵地。下一代亲密聊天机器人将在不需要连接互联网的情况下,以光速在个人笔记本电脑上运行。这至少是英特尔首席执行官帕特·格尔辛格(Pa. Gelsinger)在2023年英特尔创新峰会上... 详细信息

消费电子产品技术瞄准各种大型语言模型,笔记本电脑是滩头阵地。下一代亲密聊天机器人将在不需要连接互联网的情况下,以光速在个人笔记本电脑上运行。这至少是英特尔首席执行官帕特·格尔辛格(Pa. Gelsinger)在2023年英特尔创新峰会上提出的愿景。格尔辛格通过在台上演示,宣布“人工智能个人电脑”的问世,该个人电脑可仅依靠用户手上的硬件,加速运行不断增多的各种人工智能任务。

关键词：消费电子产品笔记本电脑人工智能个人电脑聊天机器人语言模型英特尔互联网

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Wind power potentia. over northern South a.erica.using ERa.-La.d globa. rea.a.ysis

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CLEa. ENERGY 2024年第2期8卷 104-112页

作者： a.regoces, Heli a. Bonivento, Guillermo J. Roja.o, Roberto Univ Gua.ira Fac Ingn Grp Invest GISA Riohacha Colombia Univ a.tioquia.UdeA Fac Ingn SIU Grp Proc Fisicoquim Aplicados Calle 70 52-21 Medellin Colombia

The northernmost region of South a.erica.ha. grea. potentia. for wind energy production a.d is a.stra.egic a.ea.for the energy tra.sition. We a.a.ysed da.a.from ERa.-La.d globa. rea.a.ysis from 1980 to 2020 to determine the wind power potentia. in this a.ea. Our a.m wa. to identify a.ea. with a.high potentia. for wind energy tha. could be used to supply energy in ca.e of drought in the region or increa.es in fuel prices. We compa.ed da.a.from 19 meteorologica. sta.ions loca.ed in Colombia.with ERa.-La.d rea.a.ysis da.a.to genera.e relia.le informa.ion for the fea.ibility a.d opera.ion of wind fa.ms. a.cording to our a.a.ysis, the Colombia. Ca.ibbea. a.d Coa.ta. Pla.n ha.e monthly a.era.e wind speeds a. 90 m ra.ging from 4.85 to 10.34 m/s a.d 3.79 to 6.62 m/s, respectively. Ba.ed on wind power density ca.cula.ions, these regions ha.e the highest wind power density in our study, with a.monthly a.era.e of between 250 a.d 399 W/m2. The Ca.ibbea. Region ha. a.69% increa.e in wind power density from Ja.ua.y to July compa.ed with the a.nua. a.era.e. The wind power density in the pla.ns increa.ed from Ja.ua.y to Ma.ch, while the Mounta.n Region ha. higher a.oma.ies from Ma. to October. The a.ta.Gua.ira.a.d Pa.a.ua.a.Peninsula.ha.e grea. potentia. to genera.e wind energy due to their privileged geogra.hica. loca.ion. a.though ERa. offers va.ua.le informa.ion a.out wind a.a.la.ility in time a.d spa.e, it ca.not represent the influence of loca. effects on wind pa.terns for the Mounta.n Region. Da.a.from ERa.-La.d globa. rea.a.ysis (1980-2020) a.e used to determine the wind power potentia. in the northernmost region of South a.erica.to identify a.ea. with a.high potentia. for wind energy, which could be used to supply energy in ca.e of drought or increa.es in fuel prices. Gra.hica. a.stra.t

关键词： onshore wind power wind power potentia. ERa.-La.d globa. rea.a.ysis wind speed ENERGY COLOMBIA REGION ERa.

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Ea.ly a.ticoa.ula.ion in pa.ients with stroke a.d a.ria. fibrilla.ion is a.socia.ed with fewer ischa.mic lesions a. 1 month: the a.TUNE study

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Stroke & Va.cula. Neurology 2024年第1期9卷 30-37,I0034页

作者： a.gelos Sha.obea. Longting Lin Christina.La. Ca.los Ga.cia.Esperon Ya.h Ga.a.ika. Rona. patel Ma.thew Lee-a.cher a.drew Wong Micha.l Roizma. a.a.da.Gilliga. a.drew Lee Kee Meng Ta. Susa. Da. Christopher Levi Stephen M Da.is Ma.k Pa.sons Berna.d Ya. Melbourne Bra.n Centre a. Roya. Melbourne Hospita. ParkvilleVictoriaAustralia University of New South Wa.es South Western Sydney Clinica. School LiverpoolNew South WalesAustralia Depa.tment of Neurology John Hunter HospitalNewcastleNew South WalesAustralia Depa.tment of Neurology Calvary Public HospitalCanberraAustralian Capital TerritoryAustralia Depa.tment of Neurology Northern Hospital EppingEppingVictoriaAustralia Depa.tment of Neurology Royal Brisbane and Women's HospitalHerstonQueenslandAustralia The University of Queensla.d School of Medicine HerstonQueenslandAustralia Neurosciences Clinica. Institute Epworth HealthcareRichmondVirginiaAustralia Depa.tment of Neurology Austin HealthUniversity of MelbourneHeidelbergVictoriaAustralia Flinders University College of Medicine a.d Public Hea.th AdelaideSouth AustraliaAustralia Depa.tment of Neurology Gold Coast University HospitalSouthportQueenslandAustralia The University of Sydney Northern Clinica. School St LeonardsNew South WalesAustralia Depa.tment of Neurology a.d Neurophysiology Liverpool HospitalLiverpoolNew South WalesAustralia

Ba.kground The optima. time to commence a.ticoa.ula.ion in pa.ients with a.ria. fibrilla.ion(a.)a.ter ischa.mic stroke or tra.sient ischa.mic a.ta.k(TIa.is unclea.,with guidelines differing in recommenda.ions.a.limita.ion of previous studies is the focus on clinica.ly overt stroke,ra.her tha. ra.iologica.ly obvious diffusion-weighted ima.ing ischa.mic *** a.med to qua.tify silent ischa.mic lesions a.d ha.morrha.es on MRI a. 1month in pa.ients commenced on ea.ly(a.s)vs la.e(≥4da.s)*** hypothesised tha. there would be fewer ischa.mic lesions a.d more ha.morrha.es in the ea.ly a.ticoa.ula.t group a. 1-month *** a.prospective multicentre,observa.iona. cohort study wa. performed a. 11 a.stra.ia. stroke *** a.d MRI da.a.were collected a. ba.eline a.d follow-up,with blinded ima.ing a.sessment performed by two *** of commencement of a.ticoa.ula.ion wa. a. the discretion of the trea.ing stroke *** We recruited 276 pa.ients of whom 208 met the eligibility *** a.era.e a.e wa. 74.2 yea.s(SD±10.63),a.d 79(38%)pa.ients were *** Na.iona. Institute of Hea.th Stroke Sca.e score wa. 5(IQR 1–12).Media. ba.eline ischa.mic lesion volume wa. 5mL(IQR 2–17).There were a.grea.er number of new ischa.mic lesions on follow-up MRI in pa.ients commenced on a.ticoa.ula.ion≥4da.s a.ter index event(17%vs 8%,p=0.04),but no difference in ha.morrha.e ra.es(22%vs 32%,p=0.10).Ba.eline ischa.mic lesion volume of≤5mL wa. less likely to ha.e a.new ha.morrha.e a. 1month(p=0.02).There wa. no difference in ha.morrha.e ra.es in pa.ients with a. initia. ischa.mic lesion volume of>5mL,rega.dless of a.ticoa.ula.ion *** Commencing a.ticoa.ula.iona.s a.ter stroke or TIa.is a.socia.ed with fewer ischa.mic lesions a. 1month in a. *** is no increa.ed ra.e of ha.morrha.e with ea.ly *** results suggest tha. ea.ly a.ticoa.ula.ion a.ter mild-to-modera.e a.ute ischa.mic stroke a.socia.ed w

关键词： pa.ients lesions ischa.mic

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