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How has the COVID-19 pandemic changed treatment preferences of patients with proximal ureteral stones?

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Fetal lung growth predicts the risk for early-life respiratory infections and childhood asthma

当代泌尿学（英文） 2024年第1期18卷 66-70页

作者： Ali Kaan Yildiz Ahmet Varan Hakan kurt Omer Gokhan Doluoglu Berat Cem Ozgur Department of Urology University of Medical SciencesAnkara Training and Research HospitalAnkaraTurkey

Background:The impact of the coronavirus disease 2019(COVID-19)pandemic on patient decision making remains *** study aimed to investigate the effect of the pandemic on treatment preferences of patients with proximal ureteral stones.Materials and methods:Retrospective data regarding treatment preferences of patients diagnosed with symptomatic proximal ure-teral stones between July 2018 and November 2021 at a single center were *** from 493 patients were analyzed according to 2 groups,including patients diagnosed during the COVID-19 pandemic and those diagnosed during an equivalent period of time be-fore the pandemic.Results:Preference for conservative treatment increased during the COVID-19 pandemic(p=0.009).In patients who had previously undergone shock wave lithotripsy(SWL),the preference for SWL decreased and the preference for conservative treatment increased during the COVID-19 pandemic(p=0.042).Multiple logistic regression analysis revealed a significant correlation between a preference for conservative treatment during the pandemic and no prior spontaneous stone passage(p=0.003;odds ratio[OR],2.48;95％con-fidence interval[CI],1.45-4.23),no hydronephrosis(p=0.035;OR,3.57;95％Cl,1.34-9.49),and a visual analog scale score of 4 or less(p=0.018;OR,1.97;95％Cl,1.15-3.38).Conclusions:A significant increase in the preference for conservative treatment was observed among patients diagnosed during the pandemic,and patients with a history of SWL demonstrated a preference shift from SWL to conservative treatment.

关键词： COVID-19 pandemic Treatment preference Ureter Urolithiasis

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World Journal of Pediatrics 2024年第5期20卷 481-495页

作者： Dimitra E.Zazara Olympia Giannou Steven Schepanski Mirja Pagenkemper Anastasios D.Giannou Maike Pincus Ioannis Belios Stefan Bonn Ania C.Muntau kurt Hecher Anke Diemert Petra Clara Arck Division for Experimental Feto-Maternal Medicine Department of Obstetrics and Fetal MedicineUniversity Medical Center Hamburg-Eppendorf(UKE)Martinistraße 5220251HamburgGermany University Children’s Hospital UKEHamburgGermany Computer Engineering and Informatics Department Polytechnic SchoolUniversity of PatrasPatrasGreece Institute of Developmental Neurophysiology Center for Molecular Neurobiology Hamburg(ZMNH)UKEHamburgGermany Department of Obstetrics and Fetal Medicine UKEHamburgGermany Department of General Visceral and Thoracic SurgeryUKEHamburgGermany Section of Molecular Immunology and Gastroenterology Ⅰ.Department of MedicineUKEHamburgGermany Pediatrics and Pediatric Pneumology Practice BerlinGermany Institute of Medical Systems Biology ZMNHUKEHamburgGermany Hamburg Center for Translational Immunology UKEHamburgGermany

Background Early-life respiratory infections and asthma are major health burdens during *** predicting an increased risk for early-life respiratory diseases are ***,we identified the predictive value of ultrasound-monitored fetal lung growth for the risk of early-life respiratory infections and *** Fetal lung size was serially assessed at standardized time points by transabdominal ultrasound in pregnant women participating in a pregnancy *** between fetal lung growth and respiratory infections in infancy or early-onset asthma at five years were ***-learning models relying on extreme gradient boosting regressor or classifier algorithms were developed to predict respiratory infection or asthma risk based on fetal lung *** model development and validation,study participants were randomly divided into a training and a testing group,respectively,by the employed *** Enhanced fetal lung growth throughout pregnancy predicted a lower early-life respiratory infection *** sex was associated with a higher risk for respiratory infections in *** lung growth could also predict the risk of asthma at five years of *** designed three machine-learning models to predict the risk and number of infections in infancy as well as the risk of early-onset *** models’R2 values were 0.92,0.90 and 0.93,respectively,underscoring a high accuracy and agreement between the actual and predicted *** variables included known risk factors and novel predictors,such as ultrasound-monitored fetal lung *** Sonographic monitoring of fetal lung growth allows to predict the risk for early-life respiratory infections and asthma.

关键词： Asthma Child risk Early-life respiratory infections Prenatal lung development Sexual dimorphism

ALDH Activity Correlates with Metastatic Potential in Primary Sarcomas of Bone

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Journal of Cancer Therapy 2014年第4期5卷 331-338页

作者： Nicholas Greco Trevor Schott Xiaodong Mu Adam Rothenberg Clifford Voigt Richard L. McGough III Mark Goodman Johnny Huard kurt R. weiss Department of Orthopaedic Surgery University of Pittsburgh Medical Center Pittsburgh USA

Osteosarcoma (OS), chondrosarcoma (CSA), and Ewings sarcoma (ES) are the most common primary malignancies of bone, and are rare diseases. As with all sarcomas, the prognosis of these diseases ultimately depends on the presence of metastatic disease. Survival is therefore closely linked with the biology and metastatic potential of a particular bone tumor’s cells. Here we describe a significant correlation of aldehyde dehydrogenase (ALDH) activity and the presence/absence of distant metastases in ten consecutive cases of human bone sarcomas. Additionally, cultured human CSA cells, which are historically chemo- and radio-resistant, may be sensitive to the ALDH inhibitor, disulfiram. While it is premature to draw broad conclusions from such a small series, the importance of ALDH activity and inhibition in the metastatic potential of primary bone sarcomas should be investigated further.

关键词： Osteosarcoma Chondrosarcoma Ewings Sarcoma Aldehyde Dehydrogenase Metastases

Analysis of a New Toothbrushing Technique through Plaque Removal Success

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Open Journal of Stomatology 2024年第3期14卷 133-152页

作者： Elhadi A. A. Shkorfu Serkan kurt Fatih Atalar Ali Olamat Aysel Ersoy Department of Electrical and Electronic Engineering Istanbul University-Cerrahpa&scedila Avc&imathlar Istanbul Türkiye Department of Electronics and Communication Engineering Y&imathld&imathz Technical University Istanbul Türkiye Department of Bioengineering Y&imathld&imathz Technical University Istanbul Türkiye

Background/Aims: Determining the levels of oral health and the quality of dental care are fundamental to building concepts of oral health. This study aims to assess toothbrushing techniques using a technical and physical model, clarifying how children and pre-adults learn to brush their teeth. Materials and Methods: Data were recorded from 23 participants, both male and female of various ages, using a proposed electronic toothbrush equipped with X-Y-Z axes pathways. The data, collected before and after training experiments, were processed with MATLAB to generate plots for the three axes. Results: The study revealed that most parameter values, such as Mean Difference Between Amplitudes (MAV, 6.00), Wilson Amplitude (WAMP, 179.419), and Average Amplitude Coupling (AAC, 1.270), decreased from before to after the experiments. Furthermore, the average overall epoch lengths (AVG) showed a 75% reduction in movement amplitude between the two experiments. Conclusion: Dentist observations indicated which brushing methods were acceptable or not. Analytical values suggest that individuals learn the toothbrushing technique effectively, and medical observations clearly demonstrate the success of the proposed method.

关键词： Techno-Physical Toothbrushing Oral Hygiene Education Dental Technology Plaque Analysis

Threads拟推广服务加剧与X的商业竞争

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商业周刊（中文版） 2024年第11期 12-13页

作者： kurt Wagner 程玺(译) 不详

对阵X一周年后,Threads已网罗1.75亿月活用户下一步是与X争夺广告收入。一年前,当埃隆·马斯克(Elon Musk)的社交媒体平台X(旧称推特)深陷困境之时,Meta PlatformsInc.的马克·扎克伯格(Mark Zuckerberg)把握时机推出了Threads。

关键词：把握时机广告收入推广服务商业竞争社交媒体平台

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谷歌的AI人物图像生成功能陷入困境

商业周刊（中文版） 2024年第5期 56-58页

作者： kurt Wagner Alex Barinka 孟洁冰(译) 不详

对于谷歌雄心勃勃的人工智能发展战略来说,2月原本是个铸就辉煌的月份。该公司将其聊天机器人重新命名为Gemini,并发布了两项重要产品升级,以便在利益攸关的人工智能竞赛中更好地与各方对手竞争。在此之际,谷歌还开始允许Gemini的用户... 详细信息

对于谷歌雄心勃勃的人工智能发展战略来说,2月原本是个铸就辉煌的月份。该公司将其聊天机器人重新命名为Gemini,并发布了两项重要产品升级,以便在利益攸关的人工智能竞赛中更好地与各方对手竞争。在此之际,谷歌还开始允许Gemini的用户生成逼真的人物图像。

关键词：人工智能聊天机器人谷歌图像生成产品升级 Gemini AI 重新命名

生存岋岋可危Tik Tok全力友击美国禁令

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商业周刊（中文版） 2024年第12期 14-16页

作者： Jamie Tarabay kurt Wagner 逸思(译) 不详

社交媒体平台TikTok正在利用律师、游说者和金钱与美国的一项潜在禁令抗争。TikTok动用了华盛顿的政治掮客和每小时收费达1500美元的律师,来抵御一-则新法案,该法案.规定除非TikTok的母公司字节跳动有限公司将其剥离,否则将禁止该应用。... 详细信息

社交媒体平台TikTok正在利用律师、游说者和金钱与美国的一项潜在禁令抗争。TikTok动用了华盛顿的政治掮客和每小时收费达1500美元的律师,来抵御一-则新法案,该法案.规定除非TikTok的母公司字节跳动有限公司将其剥离,否则将禁止该应用。TikTok通过多方面的努力来谋求生存,包括斥资480万美元进行广告宣传,并对美国国会和美国宪法全面施压。

关键词：美国国会广告宣传禁令新法案母公司律师游说者

Effects of magnet shapes on total harmonic distortion and cogging torque in a permanent magnet synchronous generator for wind turbines

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Clean Energy 2023年第5期7卷 1058-1068页

作者： Erol kurt Adem Dalcalı Gazi University Department of Electrical and Electronics EngineeringTechnology FacultyAnkaraTurkey Bandırma Onyedi Eylul University Department of Electrical and Electronics EngineeringFaculty of Engineering and Natural SciencesBandırmaBalıkesirTurkey National Research University TIIAME100000TashkentUzbekistan

This paper explores and theoretically reports the effects of different magnet structures on the cogging torque and the total harmonic distortion of the output waveforms from a permanent magnet *** generator is a radial flux machine and four different structures are considered for the magnet arrangement in the rotor component and modelled in the Ansys/Maxwell electromagnetic simulation *** three-phase machine exhibits different behaviours towards various magnet structures,***,inclined slotted rectangular,skewed double rectangular and inclined slotted skewed double rectangular,*** has been proven by finite element analysis and Fourier analysis that both the cogging and total harmonic distortion values vary significantly for all *** cogging torque values change in the range of 89.95 to 436.75 mNm and the lowest cogging torque is measured for the inclined slotted skewed double rectangular magnet geometry,while the conventional rectangular magnet geometry yields the worst value with 436.75 ***,the total harmonic distortion values varies between 1.63 and 3.55 for different magnetic *** the worst total harmonic distortion value is obtained from the inclined slotted rectangular magnet,the best total harmonic distortion is acquired from the skewed double rectangular *** these results will provide scientists and engineers with important information in order to obtain more efficient machines.

关键词： renewable energy wind power finite element method synchronous generator wind turbines

Sustainability of lime stabilized road subgrade in mountainous regions of Türkiye

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Journal of Mountain Science 2023年第8期20卷 2436-2452页

作者： Yavuz ABUT İlknur BOZBEY Ece kurt BAL Department of Transportation Engineering Faculty of EngineeringYalova UniversityYalova 77200Türkiye Geotechnical Engineering Division Civil Engineering DepartmentAvcilar CampusIstanbul University-CerrahpasaAvcilar/Istanbul 34320Türkiye Civil Eng. M.Sc.&Geoph.Eng.Sentez Geopier FoundationsIstanbul 34320Türkiye

In this paper the use of lime stabilized subgrade for low volume roads in two regions with high mountains and different frost penetration conditions in Türkiye was investigated in terms of design,performance,and *** on unstabilized and stabilized subgrade were designed for two regions(Izmir and Van),covering all climate *** resilient modulus of the lime stabilized subgrade with different soil pulverization levels for non-freezing and freezing conditions were taken from a previous laboratory *** effects were considered in pavement design using two different approaches,including limited subgrade frost penetration method and reduced subgrade strength *** application and evaluation were performed for all *** stabilized subgrades significantly reduced the thickness of base courses,and the benefit of lime stabilization was highly dependent on soil pulverization level.A detailed cost analysis on the unstabilized and stabilized cases found that the use of lime stabilization in the subgrade provided significant initial cost *** analysis by using the AASHTO(1993)method and KENPAVE software,and quantity effect of soil pulverization level on the performance of low volume roads from a service life perspective,show that subgrade resilient modulus can be *** is also possible to make correct performance estimation in the *** results of the study show that lime stabilization is a good solution for low volume roads in the mountainous regions of Türkiye.

关键词： Aggregate Surfaced Roads Lime Stabilization Soil Pulverization Levels Road Design Service Life Cost analyses