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Prevalence of high-grade HPV types among women in Astana, Kazakhstan (2018-2022)

Journal of Cancer Metastasis and Treatment 2023年第1期9卷 471-479页

作者： kuralay kongrtay Nazira Kadrlodinova Fatima Sultankulova Aigul Batpanova Yevgeniy Kim Danagul Zhumasheva Nasrulla Shanazarov Nazira Kamzayeva Department of Surgery School of MedicineNazarbayev UniversityAstana 010000Kazakhstan Clinical Academic Department of Women's Health University Medical CenterAstana 010000Kazakhstan Medical Outpatient Clinic Limited Liability Company"Densaulik Astana"Astana 010000Kazakhstan Center for Photodynamic Therapy Medical Centre Hospital of President’s Affairs Administration of the Republic of KazakhstanAstana 010000Kazakhstan

Background:Cervical cancer is a significant public health concern worldwide,and human papillomavirus(HPV)is the leading cause of this *** there have been some studies on the prevalence of HPV in Kazakhstan,the country faces unique challenges in preventing and treating HPV-related diseases,including limited resources,a lack of awareness about HPV,and cultural attitudes toward sexual *** research article aims to provide a comprehensive overview of HPV genotype distribution in Astana,Kazakhstan,for the last five ***:A cross-sectional study was performed from 2018 to *** population:Kazakhstani women referring to“Olympus laboratories network”settings for HPV testing age ***®Real-Time PCR kits for HPV genotyping 14 high-risk HPV types(16,18,31,33,35,39,45,51,52,56,58,59,66,68)were ***:This study revealed the increasing trend in HR-HPV prevalence among women for five sequential year *** a result,approximately 43%of women referred to the HPV testing were HR-HPV positive,with the most prevalent type being HPV 16(20%),followed by HPV types 31,52,***:By examining the latest research on HPV and cervical cancer in Kazakhstan,we hope to contribute to developing effective public health policies and interventions to help reduce these diseases'burden in this ***,the database will be established for future large-scale studies after vaccination implementation.

关键词： Human papillomavirus prevalence genotype cervical cancer

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