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Analysis of pathogenetic process of fungal rhinosinusitis: Report of two cases

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World Journal of Clinical Cases 2020年第2期8卷 451-463页

作者： Lin-Lin Wang Feng-Ji Chen Long-su Yang Jie-En Li Department of Otolaryngology Head and Neck Surgery The First Affiliated Hospital of Guangxi Medical University

BACKGROUND Fungal rhinosinusitis is an infectious and/or allergic disease caused by fungi in the sinus and nasal cavity. Due to the warm and humid climate in Guangxi Zhuang Autonomous Region, the incidence of fungal rhinosinusitis is higher than that in other provinces. However, its physiological mechanism is not yet *** every patient colonized by fungi develops a fungal infection. To a large extent, the immune status of the patient determines the nature of fungal disease in the nasal passages. The pathologic process of progression from harmless fungal colonization to fungal rhinosinusitis is unclear and has not been *** suMMURY We report two patients, one who developed fungal rhinosinusitis 1.5 years after surgery performed to treat an inverted papilloma, and the other with a history of hypertension and cerebral infarction. Both patients recovered from their surgeries. An average time of 2.5 years elapsed from the development of maxillary sinus cysts to the development of fungal *** According to these case reports, we speculate that the progression of fungal rhinosinusitis from harmless colonization to disease onset requires approximately one to three years and that the length of the process may be related to underlying diseases, surgical treatment, deficient autoimmune status,and abuse of hormone antibiotics and hormones. Additional data are needed to conduct relevant studies to appropriately prevent and treat fungal rhinosinusitis.

关键词： Fungal rhinosinusitis Aspergillosis Fungus ball Sinus surgery Classification Diagnosis Case report

Early Embryo and Larval Development of Inviable Intergeneric Hybrids Derived from Crassostrea angulata and Saccostrea cucullata

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Journal of Ocean University of China 2016年第3期15卷 515-522页

作者： su Jiaqi WANG Zhaoping ZHANG Yuehuan YAN Xiwu LI Qiongzhen YU Ruihai Key Laboratory of Mariculture of Ministry of Education Fisheries College Ocean University of China Key Laboratory of Tropical Marine Biological Resources and Ecology South China Sea Institute of OceanologyChinese Academy of Sciences Engineering Research Center of Shellfish Culture and Breeding of Liaoning Province College of Fisheries and Life Science Dalian Ocean University Key Laboratory of Mariculture Guangxi Academy of Fishery Science

To detect the intergeneric hybridization between the oyster Crassostrea angulata and Saccostrea cucullata coexisting along the southern coast of China, reciprocal crosses were conducted between the two species. Barriers for sperm recognizing, binding, penetrating the egg, and forming the pronucleus were detected by fluorescence staining. From the results, although fertilization success was observed in hybrid crosses, the overall fertilization rate was lower than that of intraspecific crosses. A large number of hybrid larvae died at 6–8 d after hatching, and those survived could not complete metamorphosis. C. angulata ♀× S. cucullata ♂ larvae had a growth rate similar to that of the maternal species, whereas S. cucullata ♀× C. angulata ♂ larvae grew the slowest among all crosses. Molecular genetics analysis revealed that hybrid progeny were amphimixis hybrids. This study demonstrated that hybrid embryos generated by crossing C. angulata and S. cucullata could develop normally to the larval state, but could not complete metamorphosis and then develop to the spat stage. Thus, there is a post-reproductive isolation between C. angulata and S. cucullata.

关键词： Crassostrea angulata Saccostrea cucullata intergeneric hybridization hybrid inviability reproductive isolation

In vitro antibacterial activity and major bioactive components of Cinnamomum verum essential oils against cariogenic bacteria,Streptococcus mutans and Streptococcus sobrinus

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Asian Pacific Journal of Tropical Biomedicine 2016年第4期6卷 308-314页

作者： Okhee Choi su Kyung Cho Junheon Kim Chung Gyoo Park Jinwoo Kim Division of Applied Life Science (BK21 Plus) Gyeongsang National University Institute of Agriculture & Life Science Gyeongsang National University

Objective:To evaluate the antibacterial activity of Cinnamomum verum(***) from32 different essential oils against cariogenic bacteria,Streptococcus mutans(***)and Streptococcus sobrinus(***).Methods:The antibacterial activities of each essential oil were individually investigated against *** and *** essential oil of *** was selected for further evaluation against *** and *** chromatography mass spectrometry was used to determine the major constituents of *** essential *** addition,the minimum inhibitory concentration(MIC) and minimum bactericidal concentration of the most effective constituent was ***:The essential oil from *** exhibited the greatest antibacterial *** chromatography mass spectrometry analysis revealed that the major components of *** essential oil were cinnamaldehyde(56.3%),cinnamyl acetate(7.1%) and bphellandrene(6.3%).The MIC of cinnamaldehyde was measured using broth dilution *** MIC of cinnamaldehyde was 0.02%(v/v) against both bacterial strains *** minimum bactericidal concentration of cinnamaldehyde against *** and *** were 0.2% and 0.1%(v/v),***:The essential oil of *** and its major component cinnamaldehyde possessed considerable in vitro antibacterial activities against cariogenic bacteria,*** and *** *** results showed that the essential oil of *** and its bioactive component,cinnamaldehyde,have potential for application as natural agents for the prevention and treatment of dental caries.

关键词： Streptococcus mutans Streptococcus sobrinus Cariogenic bacteria Essential oil Antibacterial activity Cinnamaldehyde

Molecular modification of Bacillus stearothermophilus NO_(2) cyclodextrin glucosyltransferase and preparation of α-cyclodextrin

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Systems Microbiology and Biomanufacturing 2022年第4期2卷 695-704页

作者： Fangyuan Zuo Lingqia su Demin Kong Lei Wang Jing Wu Sheng Chen State Key Laboratory of Food Science and Technology Jiangnan University1800 Lihu AvenueWuxi 214122JiangsuChina School of Biotechnology and Key Laboratory of Industrial Biotechnology Ministry of Education Jiangnan UniversityWuxiChina International Joint Laboratory On Food Safety Jiangnan UniversityWuxiChina

Cyclodextrin(CD)is produced by the catalysis of starch or starch derivatives by cyclodextrin glucosyltransferase(CGTase),and its yield is mainly limited by the product and reaction specificity of *** this study,we use CGTase derived from Bacillus stearothermophilus NO_(2),exhibiting high expression levels and good stability for molecular *** N353A mutant effectively decreases the hydrolysis activity,and the ratio of the k_(cat) values(cyclization to hydrolysis activity)is 86.46,which is threefold that of the wild *** E142P mutant effectively enhancesα-CD specificity,which increases the ratio of k_(cat) values(α-CD toβ-CD formation)from 2.18 of the wild-type to *** N353A/E142P mutant weakens the hydrolysis side reaction and enhancesα-CD specificity,and the proportion ofα-CD products is 53.67%,which is 15.62%higher than that of the *** research focuses on CGTase reaction and product specificities,which suggest a novel method for the industrial production ofα-CD.

关键词： Cyclodextrin glucosyltransferase Cyclodextrin preparation Site-directed mutation Cyclization Hydrolysis

Ada-FFL:Adaptive computing fairness federated learning

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CAAI Transactions on Intelligence Technology 2024年第3期9卷 573-584页

作者： Yue Cong Jing Qiu Kun Zhang Zhongyang Fang Chengliang Gao Shen su Zhihong Tian The Cyberspace Institute of Advanced Technology Guangzhou UniversityGuangzhouChina Pengcheng Lab ShenzhenChina Carnegie Mellon University PittsburghPennsylvaniaUSA Mohamed Bin Zayed University of Artificial Intelligence Abu DhabiUnited Arab Emirates

As the scale of federated learning expands,solving the Non-IID data problem of federated learning has become a key challenge of *** existing solutions generally aim to solve the overall performance improvement of all clients;however,the overall performance improvement often sacrifices the performance of certain clients,such as clients with less *** fairness may greatly reduce the willingness of some clients to participate in federated *** order to solve the above problem,the authors propose Ada-FFL,an adaptive fairness federated aggregation learning algorithm,which can dynamically adjust the fairness coefficient according to the update of the local models,ensuring the convergence performance of the global model and the fairness between federated learning *** integrating coarse-grained and fine-grained equity solutions,the authors evaluate the deviation of local models by considering both global equity and individual equity,then the weight ratio will be dynamically allocated for each client based on the evaluated deviation value,which can ensure that the update differences of local models are fully considered in each round of ***,by combining a regularisation term to limit the local model update to be closer to the global model,the sensitivity of the model to input perturbations can be reduced,and the generalisation ability of the global model can be *** numerous experiments on several federal data sets,the authors show that our method has more advantages in convergence effect and fairness than the existing baselines.

关键词： adaptive fariness aggregation fairness federated learning non-IID

Prison Term Prediction on Criminal Case Description with Deep Learning

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Computers, Materials & Continua 2020年第3期62卷 1217-1231页

作者： Shang Li Hongli Zhang Lin Ye Shen su Xiaoding Guo Haining Yu Binxing Fang School of Computer Science and Technology Harbin Institute of TechnologyHarbinChina Cyberspace Institute of Advanced Technology Guangzhou UniversityGuangzhouChina Department of Computer Science City University of Hong KongKowloon TongHong Kong

The task of prison term prediction is to predict the term of penalty based on textual fact description for a certain type of criminal *** advances in deep learning frameworks inspire us to propose a two-step method to address this *** obtain a better understanding and more specific representation of the legal texts,we summarize a judgment model according to relevant law articles and then apply it in the extraction of case feature from judgment *** formalizing prison term prediction as a regression problem,we adopt the linear regression model and the neural network model to train the prison term *** experiments,we construct a real-world dataset of theft case judgment *** results demonstrate that our method can effectively extract judgment-specific case features from textual fact *** best performance of the proposed predictor is obtained with a mean absolute error of 3.2087 months,and the accuracy of 72.54%and 90.01%at the error upper bounds of three and six months,respectively.

关键词： Neural networks prison term prediction criminal case text comprehension

Electrospun ZnSnO_(3)/PVDF‑HFP Nanofibrous Triboelectric Films for Efficient Mechanical Energy Harvesting

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Advanced Fiber Materials 2023年第5期5卷 1685-1698页

作者： Venkata Siva Kavarthapu Sontyana Adonijah Graham Punnarao Manchi Mandar Vasant Paranjape Jae su Yu Department of Electronics and Information Convergence Engineering Institute for Wearable Convergence ElectronicsKyung Hee University1732 Deogyeong‑daeroGiheung‑guYongin‑SiGyeonggi‑do 17104Republic of Korea

Nowadays,triboelectric nanogenerators(TENGs)are one of the most emerging technologies owing to their easy and costeffective device *** can harvest mechanical energy from our living ***,we synthesized dielectric zinc tin oxide(ZnSnO_(3))nanoparticles(NPs)by a hydrothermal *** ZnSnO_(3)NPs provide a dielectric and piezoelectric effect,which can efficiently enhance the output electrical performance of the proposed *** prepared ZnSnO_(3)NPs were embedded into a polyvinylidene fluoride hexafluoropropylene(PVDF-HFP)polymer to prepare ZnSnO_(3)/PVDF-HFP nanofibrous films to fabricate a *** output performance of TENG was investigated and optimized by varying the loading concentration of ZnSnO_(3)NPs in PVDF-HFP fibrous *** highest voltage,current,charge density,and power density from the fabricated TENG were achieved as~138 V,~5μA,~52μC/m2,and~1.6 W/m2,***,the robustness of the TENG was studied via the long-term mechanical stability ***,the practical and real-time application of the TENG was demonstrated by harvesting mechanical energy to power low-power portable electronic ***,the materials used in the TENG were combined into a skipping rope to harvest biomechanical/mechanical energy while exercising.

关键词： s ZnSnO_(3)nanoparticles ZnSnO_(3)/PVDF-HFP fibrous films Triboelectric nanogenerators Mechanical energy harvesting

Location Privacy in Device-Dependent Location-Based Services:Challenges and Solution

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Computers, Materials & Continua 2019年第6期59卷 983-993页

作者： Yuhang Wang Yanbin sun Shen su Zhihong Tian Mohan Li Jing Qiu Xianzhi Wang Cyberspace Institute of Advanced Technology Guangzhou UniversityGuangzhou510006China School of Software University of Technology SydneySydney NSW 2007Australia

With the evolution of location-based services(LBS),a new type of LBS has already gain a lot of attention and implementation,we name this kind of LBS as the Device-Dependent LBS(DLBS).In DLBS,the service provider(SP)will not only send the information according to the user’s location,more significant,he also provides a service device which will be carried by the *** has been successfully practised in some of the large cities around the world,for example,the shared bicycle in Beijing and *** this paper,we,for the first time,blow the whistle of the new location privacy challenges caused by DLBS,since the service device is enabled to perform the localization without the permission of the *** conquer these threats,we design a service architecture along with a credit system between DLBS provider and the *** credit system tie together the DLBS device usability with the curious behaviour upon user’s location privacy,DLBS provider has to sacrifice their revenue in order to gain extra location information of their *** make the simulation of our proposed scheme and the result convince its effectiveness.

关键词： Location privacy device-dependent location-based service location-based service credit system location privacy preserving mechanism shared bicycle

A Review on the Security of the Ethereum-Based DeFi Ecosystem

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Computer Modeling in Engineering & Sciences 2024年第4期139卷 69-101页

作者： Yue Xue Dunqiu Fan Shen su Jialu Fu Ning Hu Wenmao Liu Zhihong Tian Cyberspace Institute of Advanced Technology Guangzhou UniversityGuanzhou510000China Innovation Center NSFOCUS Inc.Beijing100089China Engineering Research Center of Integration and Application of Digital Learning Technology Ministry of EducationBeijing100816China

Decentralized finance(DeFi)is a general term for a series of financial products and *** is based on blockchain technology and has attracted people’s attention because of its open,transparent,and intermediary *** them,the DeFi ecosystem based on Ethereum-based blockchains attracts the most ***,the current decentralized financial system built on the Ethereum architecture has been exposed to many smart contract vulnerabilities during the last few ***,we believe it is time to improve the understanding of the prevailing Ethereum-based DeFi ecosystem security *** that end,we investigate the Ethereum-based DeFi security issues:1)inherited from the real-world financial system,which can be solved by macro-control;2)induced by the problems of blockchain architecture,which require a better blockchain platform;3)caused by DeFi invented applications,which should be focused on during the project *** on that,we further discuss the current solutions and potential directions ofDeFi *** to our research,we could provide a comprehensive vision to the research community for the improvement of Ethereum-basedDeFi ecosystem security.

关键词： Blockchain smart contract decentralized finance DeFi security