检索结果-南通市图书馆

Journal of Animal Science and Biotechnology 2024年第3期15卷 1119-1130页

作者： Tae Hong Kang Sang In lee Department of Animal Science and Biotechnology Kyungpook National UniversitySangjuGyeong‑Sangbuk‑Do 37224Republic of Korea Research Institute for Innovative Animal Science Kyungpook National University37224SangjuGyeong‑Sangbuk‑DoRepublic of Korea

Background Deoxynivalenol(DON)is a mycotoxin that has received recognition worldwide because of its ability to cause growth delay,nutrient malabsorption,weight loss,emesis,and a reduction of feed intake in *** DON-contaminated feedstuff is absorbed in the gastrointestinal tract,we used chicken organoids to assess the DON-induced dysfunction of the small *** We established a culture system using chicken organoids and characterized the organoids at passages 1 and *** confirmed the mRNA expression levels of various cell markers in the organoids,such as KI67,leucine-rich repeat containing G protein-coupled receptor 5(Lgr5),mucin 2(MUC2),chromogranin A(CHGA),cytokeratin 19(CK19),lysozyme(LYZ),and microtubule-associated doublecortin-like kinase 1(DCLK1),and compared the results to those of the small *** results showed that the organoids displayed functional similarities in permeability compared to the small *** damaged the tight junctions of the organoids,which resulted in increased *** Our organoid culture displayed topological,genetic,and functional similarities with the small intes-tine *** on these similarities,we confirmed that DON causes small intestine *** organoids offer a practical model for the research of harmful substances.

关键词： Barrier function Deoxynivalenol Organoids

Effect of characteristics and distribution of Mg_(17)Al_(12)precipitates on tensile and bending properties of high-Al-containing Mg alloys

在线全文

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2024年第2期12卷 779-793页

作者： Sumi Jo Gyo Myeong lee Jong Un lee Young Min Kim Sung Hyuk Park School of Materials Science and Engineering Kyungpook National UniversityDaegu 41566Republic of Korea Department of Magnesium Korea Institute of Materials ScienceChangwon 51508Republic of Korea

This study investigates the effect of characteristics and distribution of Mg_(17)Al_(12)precipitates on the uniaxial tensile and three-point bending properties of extruded Mg alloys containing high Al *** extruded Mg–9Al–1Zn–0.3Mn(AZ91)alloy contains lamellar-structured Mg_(17)Al_(12)discontinuous precipitates along the grain boundaries,which are formed via static precipitation during natural air *** extruded Mg–11Al–1Zn–0.3Mn(AZ111)alloy contains spherical Mg_(17)Al_(12)precipitates at the grain boundaries and inside the grains,which are formed via dynamic precipitation during *** to inhomogeneous distribution of precipitates,the AZ111 alloy consists of two different precipitate regions:precipitate-rich region with numerous precipitates and finer grains and precipitate-scarce region with a few precipitates and coarser *** AZ111 alloy exhibits a higher tensile strength than the AZ91 alloy because its smaller grain size and more abundant precipitates result in stronger grain-boundary hardening and precipitation hardening effects,***,the tensile elongation of the AZ111 alloy is lower than that of the AZ91 alloy because the weak cohesion between the dynamic precipitates and the matrix facilitates the crack initiation and *** bending,a macrocrack initiates on the outer surface of bending specimen in both *** AZ111 alloy exhibits higher bending yield strength and lower failure bending strain than the AZ91 *** bending specimens of the AZ91 alloy have similar bending formability,whereas those of the AZ111 alloy exhibit considerable differences in bending formability and crack propagation behavior,depending on the distribution and number density of precipitates in the *** bending specimens of the AZ111 alloy,it is found that the failure bending strain(ε_(f,bending))is inversely proportional to the area fraction of precipitates in the outer zone of bending specimen(A_(ppt)),with a relation

关键词： Mg–Al alloy Extrusion Bending Precipitation Microstructure

Enhanced prediction of anisotropic deformation behavior using machine learning with data augmentation

在线全文

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2024年第1期12卷 186-196页

作者： Sujeong Byun Jinyeong Yu Seho Cheon Seong Ho lee Sung Hyuk Park Taekyung lee School of Mechanical Engineering Pusan National UniversityBusan 46241South Korea School of Materials Science and Engineering Kyungpook National UniversityDaegu 41566South Korea

Mg alloys possess an inherent plastic anisotropy owing to the selective activation of deformation mechanisms depending on the loading *** characteristic results in a diverse range of flow curves that vary with a deformation *** study proposes a novel approach for accurately predicting an anisotropic deformation behavior of wrought Mg alloys using machine learning(ML)with data *** developed model combines four key strategies from data science:learning the entire flow curves,generative adversarial networks(GAN),algorithm-driven hyperparameter tuning,and gated recurrent unit(GRU)*** proposed model,namely GAN-aided GRU,was extensively evaluated for various predictive scenarios,such as interpolation,extrapolation,and a limited dataset *** model exhibited significant predictability and improved generalizability for estimating the anisotropic compressive behavior of ZK60 Mg alloys under 11 annealing conditions and for three loading *** GAN-aided GRU results were superior to those of previous ML models and constitutive *** superior performance was attributed to hyperparameter optimization,GAN-based data augmentation,and the inherent predictivity of the GRU for *** a first attempt to employ ML techniques other than artificial neural networks,this study proposes a novel perspective on predicting the anisotropic deformation behaviors of wrought Mg alloys.

关键词： Plastic anisotropy Compression Annealing Machine learning Data augmentation

Exploring the relationship between rarity and price of profile picture NFT:A formal concept analysis on the BAYC NFT collection

在线全文

学校读者我要写书评

暂无评论

Blockchain(Research and Applications) 2024年第2期5卷 140-150页

作者： Heejung lee Geun-Cheol lee Hoon-Young Koo School of Interdisciplinary Industrial Studies Hanyang University222 Wangsimni-roSeongdong-guSeoul04763Republic of Korea College of Business Administration Konkuk University120 Neungdong-roGwangjin-guSeoul05029Republic of Korea School of Business Chungnam National University99 Daehak-roYuseong-guDaejeon34134Republic of Korea

Non-fungible token(NFT)is a digital asset whose ownership can be validated and controlled via blockchain *** NFT market is a rapidly growing field,and the rarity of NFT is an essential factor that affects its price,as scarcity leads to higher *** study focuses on the BAYC NFT collection,which is a successful and representative collection of profile picture NFT,and analyzes how rarity affects NFT *** paper investigates the relationship between the rarity and price of the BAYC NFT collection using formal concept analysis(FCA)*** results show that rarity is a major factor influencing the price of NFT and the effect is more apparent in the medium rarity *** rarity is very high or very low,other factors become significant determinants,such as the uniqueness and appeal of NFT,and even the naturalness of NFT *** research highlights the importance of considering rarity when assessing NFT and underscores the need for a comprehensive evaluation of NFT *** study also provides valuable insights into the NFT market and can be useful for NFT investors,creators,and ***,the usefulness of FCA as a tool for quantifying NFT rarity and evaluating NFT price was demonstrated.

关键词： NFT valuation Formal concept analysis Rarity

Tracking of horizontal alignment of the long and large diameter uncharged hole in NATM tunnel

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Underground Space 2024年第3期16卷 18-28页

作者： Min-Seong Kim Sean Seungwon lee Department of Energy and Resources Engineering Chonnam National UniversityGwangju 61186Republic of Korea Department of Earth Resources and Environmental Engineering Hanyang UniversitySeoul 04763Republic of Korea

The long and large diameter uncharged hole boring(LLB)method is a cut blasting method that minimizes blast-induced vibrations by creating long and large diameter uncharged holes at the excavation face of tunnels prior to tunnel *** in this method typically uses a 50 m long with a 382 mm diameter hammer bit in the horizontal direction at the tunnel ***,the significant weight and uni-directional rotation of the rod head,as well as variables such as geological characteristics,machine conditions,and inexperienced operators result in significant deviation from the target borehole alignment that hinders the vibration-dampening effect of the uncharged ***,since there is no method to verify the alignment of the boreholes until main tunnel construction,borehole misalignment is often not discovered until weeks after construction,which requires tunnel construction to cease until the equipment can be remobilized and an additional borehole be created,causing significant delays and increased costs for the entire tunnel *** this study,the borehole alignment tracking and ground exploration system(BGS)is developed to predict and monitor the quality and alignment of boreholes for cut blasting methods such as the LLB methods immediately after *** BGS was subsequently tested at a subway construction site to evaluate its performance in the *** measurements yielded by the BGS were compared with manually measured boring positions at every 5 m along the *** the BGS showed a maximum deviation of approximately 12%at a local point where the hole surface was relatively rough,the accuracy for the final boring position was approximately 97%,demonstrating excellent precision of the alignment tracking *** BGS demonstrates excellent performance in predicting ground conditions and the boring quality of a cut hole immediately after drilling,and shows promise in various other applications for monitoring borehole alignment.

关键词： Tunnel blasting LLB method Drilling deviation Vertical sagging Horizontal alignment tracking BGS

Classification and technical target of water electrolysis for hydrogen production

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第8期95卷 554-576,I0012页

作者： Kahyun Ham Sooan Bae Jaeyoung lee Ertl Center for Electrochemistry and Catalysis Gwangju Institute of Science and Technology(GIST)123 Cheomdangwagi-RoBuk-guGwangju 61005South Korea Department of Heterogeneous Reactions Max Planck Institute for Chemical Energy ConversionStiftstr.34-36Mülheim an der RuhrGermany School of Earth Sciences and Environmental Engineering GIST123 CheomdangwagiroBuk-guGwangju 61005South Korea International Future Research Center of Chemical Energy Storage and Conversion Processes GIST123 CheomdangwagiroBuk-guGwangju 61005South Korea eSuS Co. Ltd.#408S6 BuildingSchool of Environment and Energy EngineeringGIST123 CheomdangwagiroBuk-guGwangju 61005South Korea

Continuous efforts are underway to reduce carbon emissions worldwide in response to global climate *** electrolysis technology,in conjunction with renewable energy,is considered the most feasible hydrogen production technology based on the viable possibility of large-scale hydrogen production and the zero-carbon-emission nature of the ***,for hydrogen produced via water electrolysis systems to be utilized in various fields in practice,the unit cost of hydrogen production must be reduced to$1/kg H_(2).To achieve this unit cost,technical targets for water electrolysis have been suggested regarding components in the *** this paper,the types of water electrolysis systems and the limitations of water electrolysis system components are *** suggest guideline with recent trend for achieving this technical target and insights for the potential utilization of water electrolysis technology.

关键词： Water electrolysis Hydrogen production Technical target Electrochemistry

A survey on the real-world clinical utilization of a traditional acupuncture in Republic of Korea:Sa-am acupuncture

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Medicine 2024年第5期22卷 570-578页

作者： Ji-Yeun Park Ye-Seul lee Hi-Joon Park Seungmin Kathy lee Ji-Won lee Song-Yi Kim College of Korean Medicine Daejeon UniversityDaejeon 34520Republic of Korea Jaseng Spine and Joint Research Institute Jaseng Medical FoundationSeoul 06110Republic of Korea Acupuncture and Meridian Science Research Center Kyung Hee UniversitySeoul 02447Republic of Korea Department of Korean Medicine Korean Medical CenterLusail 201184Qatar Virginia University of Integrative Medicine ViennaVA 22182USA Department of Anatomy and Acupoint College of Korean MedicineGachon UniversitySeongnamGyeonggi 13120Republic of Korea Department of Ophthalmology Otolaryngologyand DermatologyCollege of Korean MedicineDongguk UniversityGoyangGyeonggi 10326Republic of Korea

Objective This study investigated the clinical details and usage of Sa-am acupuncture in Korean medicine clinics and explored how practicing Korean medicine doctors(KMDs)think about Sa-am *** We conducted a questionnaire-based survey of KMDs who utilize Sa-am acupuncture in their *** study comprehensively investigated issues related to clinical application of Sa-am acupuncture,needling techniques used during treatment,training methods,and directions for its future *** We analyzed 572 *** average of 50%of the patients visiting Korean medicine clinics were receiving Sa-am *** most prevalent indication for Sa-am acupuncture use was digestive *** patients’appetite level and digestive function were most frequently used indicators for selecting acupuncture *** prescription compositions,Jung-Gyuk formulas were more frequently used than Seung-Gyuk *** the needle along the flow of the channel or against the flow of the channel was most *** acupuncture style most frequently used in combination with Sa-am acupuncture was Ashi point *** of Sa-am acupuncture included its versatility,easy application,and good *** included the lack of rigorous education and training programs,difficulty in applying the principles for beginners,and insufficient clinical research *** In clinics where Sa-am acupuncture is available,KMDs were providing Sa-am acupuncture to about half of their *** were not using all of the tonification and sedation techniques which may be due to time constraints or simply a lack of ***-am acupuncture demonstrated high utility in clinical practice and high satisfaction based on the efficacy and *** training programs and high-quality research are needed to help expand the use of Sa-am acupuncture.

关键词： Sa-am acupuncture Traditional East Asian medicine Acupuncture education Acupoint selection

Nuclear receptor coactivator 6 is a critical regulator of NLRP3 inflammasome activation and gouty arthritis

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2024年第3期21卷 227-244页

作者： Kang-Gu lee Bong-Ki Hong Saseong lee Naeun lee Seung-Whan Kim Donghyun Kim Wan-Uk Kim Center for Integrative Rheumatoid Transcriptomics and Dynamics The Catholic University of KoreaSeoul 06591Republic of Korea Department of Biomedicine&Health Sciences The Catholic University of KoreaSeoul 06591Republic of Korea Department of Pharmacology Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505Republic of Korea Bio-Medical Institute of Technology University of UlsanSeoul 05505Republic of Korea Department of Microbiology and Immunology Seoul National University College of MedicineSeoul 03080Republic of Korea Institute of Infectious Diseases Seoul National University College of MedicineSeoul 03080Republic of Korea Division of Rheumatology Department of Internal MedicineThe Catholic University of KoreaSeoul 06591Republic of Korea

Transcriptional coactivators regulate the rate of gene expression in the *** receptor coactivator 6(NCOA6),a coactivator,has been implicated in embryonic development,metabolism,and cancer pathogenesis,but its role in innate immunity and inflammatory diseases remains ***,we demonstrated that NCOA6 was expressed in monocytes and macrophages and that its level was increased under proinflammatory ***,nuclear NCOA6 was found to translocate to the cytoplasm in activated monocytes and then become incorporated into the inflammasome with NLRP3 and ASC,forming cytoplasmic ***,NCOA6 associated with the ATP hydrolysis motifs in the NACHT domain of NLRP3,promoting the oligomerization of NLRP3 and ASC and thereby instigating the production of IL-1βand active *** note,Ncoa6 deficiency markedly inhibited NLRP3 hyperactivation caused by the Nlrp3^(R258W) gain-of-function mutation in *** ablation of Ncoa6 substantially attenuated the severity of two NLRP3-dependent diseases,folic-induced acute tubular necrosis and crystal-induced arthritis,in *** with these findings,NCOA6 was highly expressed in macrophages derived from gout patients,and NCOA6-positive macrophages were significantly enriched in gout macrophages according to the transcriptome profiling ***,NCOA6 is a critical regulator of NLRP3 inflammasome activation and is therefore a promising target for NLRP3-dependent diseases,including gout.

关键词： Nuclear receptor coactivator 6 Nuclear-to-cytoplasmic translocation NLRP3 inflammasome NACHT domain Gouty arthritis

Nanoscale materials transformations revealed by liquid phase TEM

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第10期17卷 9152-9165页

作者： Qiubo Zhang Daewon lee Haimei Zheng Materials Sciences Division Lawrence Berkeley National LaboratoryBerkeleyCalifornia 94720USA Department of Materials Science and Engineering University of CaliforniaBerkeleyCalifornia 94720USA

Nanoscale materials often undergo structural,morphological,or chemical changes,especially in solution processes,where heterogeneity and defects may significantly impact the transformation *** phase transmission electron microscopy(TEM),allowing us to track dynamic transformations of individual nanoparticles,has become a powerful platform to reveal nanoscale materials transformation pathways and address challenging issues that are hard to approach by other *** the development of modern liquid cells,implementing advanced imaging and image analysis methods,and strategically exploring diverse systems,significant advances have been made in liquid phase TEM,including improved high-resolution imaging through liquids at the atomic level and remarkable capabilities in handling complex systems and *** the past more than a decade,we spent much effort in developing and applying liquid phase TEM to elucidate how atomic level heterogeneity and defects impact various physicochemical processes in liquids,such as growth,self-assembly of nanoparticles,etching/corrosion,electrodeposition of alkali metals,catalyst restructuring during reactions,and so *** article provides a brief review of the liquid phase TEM study of nanoscale materials transformations,focusing on the growth of nanomaterials with distinct shape/hierarchical structures,such as one-dimensional(1D)growth by nanoparticle attachment,two-dimensional(2D)growth with nanoparticles as intermediates,core-shell structure ripening,solid-liquid interfaces including those in batteries and electrocatalysis,highlighting the impacts of heterogeneity and defects on broad nanoscale transformation pathways.

关键词： liquid phase transmission electron microscopy(TEM) liquid cells nanomaterials growth transformations pathways solid-liquid interface heterogeneity and fluctuations

Heat-induced leaf epidermal cell damage triggers autophagy-mediated mesophyll cell expansion in Arabidopsis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plant Communications 2024年第3期5卷 5-8页

作者： Yunji Namgung Hong Gil lee Hongwoo lee Pil Joon Seo Department of Chemistry Seoul National UniversitySeoul 08826Republic of Korea Plant Genomics and Breeding Institute Seoul National UniversitySeoul 08826Republic of Korea Research Institute of Basic Sciences Seoul National UniversitySeoul 08826Republic of Korea

Dear Editor,Plants have evolved intricate mechanisms to recognize fluctuating environments,relay signals,and ultimately recover from the cellular and tissue damage imposed by environmental *** wounding,mechanical damage is recognized via cellular compounds released from damaged cells(Vega-Munoz et al.,2020)or changes in turgor pressure and cell-wall properties(Hoermayer et al.,2020).

关键词： damage Arabidopsis wound