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Malignant biphasic tumor of the uterus: A case report and review

The Chinese-German Journal of Clinical Oncology 2013年第5期12卷 249-251页

作者： Umesh Das Vishwanath Sathyanarayanan Nagesh Taterao Sirsath Champaka G lakshmaiah kuntejowdahalli Channaviriappa Department of Medical Oncology Kidwai Memorial Institute of Oncology Department of Pathology Kidwai Memorial Institute of Oncology

We present a rare case of a 50-year old lady who presented with pain abdomen and bleeding per vaginum of 3 months duration. Per vaginal examination revealed an exophytic growth arising from vault. Histopathological examination of the vault biopsy showed malignant neoplasm with features suggestive of carcinosarcoma of vault with immunohistochemistry showing stromal cells positive for CD10 and negative for SMA. Ki67 index was 40%-50%. She received external beam radiotherapy to pelvis 50.4 Gy/25 fractions but did not respond to the same. The lesion was not surgically resectable and hence referred to the division of medical oncology for chemotherapy. She was started on ifosphamide with cisplatin with growth factor support. It was planned to do a reassessment after 3 cycles of chemotherapy, but patient succumbed to the illness.

关键词： cercinosercome uterus vault

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Is pregnancy wise after 12-year chemotherapy of chronic myeloid leukemia woman?

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Journal of Cancer Metastasis and Treatment 2015年第1期1卷 208-210页

作者： Umesh Das Gurulingaiah Venkata Giri kuntejowdahalli lakshmaiah Suresh Tagarapura Lokanatha Dasappa Govind Babu Linu Abraham Jacob Suresh Babu Department of Medical Oncology Kidwai Memorial Institute of OncologyBengaluru 560029KarnatakaIndia.

Diagnosis of leukemia during pregnancy is a dramatic event that poses challenges to the pregnant woman,the family,and *** myeloid leukemia(CML)comprises up to 10%of pregnancy-associated *** is no specifi c guideline for CML management in pregnant *** study reported a case of successful pregnancy after 12 years of chemotherapy including tyrosine kinase inhibitor for *** after 12 years of continuous chemotherapy is rare,which also led a challenge for medical oncologists and patient as *** study described the assessment of the risk balance and benefi t and management of such a patient.

关键词： Chronic myeloid leukemia imatinib pregnancy tyrosine kinase inhibitor

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