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肾素血管紧张素醛固酮系统抑制剂与新型冠状病毒肺炎易感性和死亡率关系的荟萃分析

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中华高血压杂志 2021年第8期29卷 783-783页

作者：周卫(译) 练桂丽(审校) Yokoyama Y Aikawa t takagi H Briasoulis A kuno t 不详

有人认为使用血管紧张素转换酶抑制药(angiotensin-converting enzyme inhibitor,ACEI)和血管紧张素受体阻滞药(angiotensin receptor blocker,ARB)可能会改变人类对新型冠状病毒肺炎(corona virus disease 2019,COVID-19)的易感性。因此,研究者进行两次荟萃分析,以评估ACEI和ARB对COVID-19的死亡率和易感性的影响。研究者检索Pubmed和EMBASE数据库,截至2020年6月,纳入研究接受或未接受ACEI和/或ARB治疗患者COVID-19检测阳性率和院内死亡率的临床试验。第一项分析评估COVID-19的检测阳性率。

关键词：血管紧张素转换酶抑制药荟萃分析新型冠状病毒检测阳性率临床试验院内死亡率 angiotensin ACEI

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Evaluation of periglacial landforms and formation of soil properties on the Mount Honaz,SW türkiye

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Journal of Mountain Science 2024年第9期21卷 3047-3067页

作者： SERİN Soner UNCU Levent DEDE Volkan tÜRKEŞMurat Institute of Social Sciences İstanbul Universityİstanbul 34119Türkiye Department of Geography BilecikŞeyh Edebali UniversityBilecik 11234Türkiye Department of Geography Ardahan UniversityArdahan 75002Türkiye Center for Climate Change and Policy Studies Boğaziçi Universityİstanbul 34342Türkiye

the main aim of this study is to explain periglacial processes on the summits of Mount Honaz(2571 m a.s.l.),define periglacial landforms,and determine the relationships between morphometric features and topographic *** circles,stony earth circles,non sorted steps,and non sorted stripes were identified on the summits of Mount ***'s correlation coefficient(r)and linear regression analyses were performed by taking metric measurements from 125 periglacial landforms to describe their morphometric features(length,width,height)of periglacial landforms and explain the relationships between them and topographic factors(elevation,slope).to explain the relationships between periglacial landforms and soil properties,soil samples from 11 periglacial landforms were taken and *** landforms,which continue to develop on the summits of Mount Honaz today,have been evaluated with present climate *** of soil samples indicates a notable impact of parent material on the genesis of periglacial *** high ratio of organic matter in mud circle and non sorted step landforms and the high lime ratio in stony earth circle landforms prove a strong relationship between the formation mechanisms of landforms and the soil ***,it is consistent with the findings obtained from the analysis that severe periglacial processes and washing and scavenging events are experienced more on the northern slopes.

关键词： Periglacial processes and geomorphology Soil analysis Morphometric analysis Mount Honaz türkiye

Preparation of microparticles and nanoparticles using membrane-assisted dispersion,micromixing,and evaporation processes

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Particuology 2024年第1期84卷 30-44页

作者： Goran t.Vladisavljevic Chemical Engineering Department Loughborough UniversityLoughboroughLeicestershire LE113TUUnited Kingdom

Synthetic microporous membranes are increasingly used for energy-efficient and controlled production of micro-and nanoparticles and micro-and nanoemulsions with tuneable morphology and physico-chemical properties through various micromixing,emulsification,and evaporation *** emul-sification processes,the membrane pores are used for dispersed phase injection and size-controlled generation of droplets and droplet-templated *** micromixing processes,membrane is utilised as a micromixer for mixing two miscible liquids,usually solvent and antisolvent-rich solutions,which leads to the creation of supersaturation and subsequent nanoprecipitation or *** mem-brane evaporation processes,membrane is used to prevent phase dispersion while allowing efficient molecular diffusion of solvent and/or antisolvent vapour through gas-filled *** dispersion processes can be operated continuously by decoupling shear stress on the membrane surface from cross flow using tube insets,flow pulsations,swirling flow,membrane oscillations or membrane *** generation and solidification can be performed continuously in a single pass by connecting membrane module with a downstream *** dispersion processes can be used for pro-duction of nanoparticles such as nanovesicles(liposomes,micelles,ethosomes,and niosomes),nanogels,polymeric,lipid and metallic nanoparticles,and *** main advantages of membrane-assisted particle generation are in low energy consumption,controlled geometry and hydrodynamic conditions at the microscale level,flexible throughput due to modular and scalable design of membrane devices,and a wide choice of available microporous membranes with various wall porosities,wetta-bilities,pore sizes,and pore morphologies to suit different applications.

关键词： Nanoparticles Microparticles Nanoemulsions Microemulsions Microporous membrane Crystallisation Flash nanoprecipitation Emulsification Zero liquid discharge

Late Ordovician Mass Extinction: Earth, fire and ice

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National Science Review 2024年第1期11卷 51-65页

作者： David A.t.Harper Palaeoecosystems Group Department of Earth SciencesDurham University

the Late Ordovician Mass Extinction was the earliest of the ‘big’ five extinction events and the earliest to affect the trajectory of metazoan life. two phases have been identified near the start of the Hirnantian period and in the middle. It was a massive taxonomic extinction, a weak phylogenetic extinction and a relatively benign ecological extinction. A rapid cooling, triggering a major ice age that reduced the temperature of surface waters, prompted a drop in sea level of some 100 m and introduced toxic bottom waters onto the shelves. these symptoms of more fundamental planetary processes have been associated with a range of factors with an underlying driver identified as volcanicity. Volcanic eruptions, and other products, may have extended back in time to at least the Sandbian and early Katian, suggesting the extinctions were more protracted and influential than hitherto documented.

关键词： Ordovician LOME paleoecology palaeobiogeography biotas

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小型非道路用共轨直喷式柴油机的技术理念

汽车与新动力 2014年第1期46卷 44-47页

作者： t.Hasegawa t.kuno K.Kita A.Kai Y.takemura O.Yoshii t.Okazaki H.Miyazaki 孙丹红

近年来,由于对工业用发动机运行平顺性和低燃油耗方面的要求日益提高,因此,要求农业、园林及工程机械等非道路用发动机具有高功率、低燃油耗和低噪声的特点。此外,即使是小型发动机,其电子控制装置的发展趋势也需保持一致。基于这些背景... 详细信息

近年来,由于对工业用发动机运行平顺性和低燃油耗方面的要求日益提高,因此,要求农业、园林及工程机械等非道路用发动机具有高功率、低燃油耗和低噪声的特点。此外,即使是小型发动机,其电子控制装置的发展趋势也需保持一致。基于这些背景,开发了采用共轨燃油喷射系统的新型非道路用直喷式柴油机,以满足上述要求。评述了在小排量非道路用柴油机上采用共轨燃油喷射系统,以及优化燃烧系统和喷油特性的技术。

关键词：直喷式柴油机共轨燃油喷射系统进气涡流喷油参数

Beta-lactam antibiotic resistance among Escherichia coli isolates from patients with urinary tract infections in Vietnam:A systematic review and meta-analysis

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Asian Pacific Journal of tropical Medicine 2024年第6期17卷 243-255,I0001-I0003页

作者： Dat t Nguyen Princess Margaret Cancer Centre University Health NetworkTorontoOntarioCanada

Objective:to investigate the evolving patterns of antimicrobial resistance against beta-lactam antibiotics in Escherichia coli isolates from urinary tract infection patients in Vietnam,covering the period from 2005 to ***:29 Descriptive studies published between 2010 and 2022 in English and Vietnamese were included in the *** on resistance rates to beta-lactam antibiotics,including cephalosporins and carbapenems,were extracted and *** pooled resistance rates were calculated using random-effects *** trends in resistance were assessed using linear regression ***:Among the beta-lactam antibiotics studied,Escherichia coli exhibited varying levels of resistance,with cephalosporins showing higher resistance rates compared to *** pooled resistance rates were 66%for cefotaxime,65%for ceftriaxone,54%for ceftazidime,and 56%for *** contrast,carbapenems demonstrated lower resistance rates,with weighted pooled resistance rates ranging from 3%to 4%for meropenem,ertapenem,and *** rates were also observed for amoxicillin/clavulanate(35%),ticarcillin/clavulanate(26%),and piperacillin/tazobactam(12%).Significant annual increases in resistance were noted for imipenem(0.56%,Pthis study highlights the critical issue of antimicrobial resistance in urinary tract infections in Vietnam and emphasizes the importance of prudent antibiotic use and the regular monitoring of resistance *** insights are useful for guiding healthcare professionals in optimizing treatment strategies and for policymakers in formulating evidence-based clinical guidelines to combat antibiotic resistance effectively.

关键词： Antimicrobial resistance Urinary tract infection Vietnam

A novel strategy for ionomer coating of Ag nanoparticles used for the electrochemical reduction of CO2 to CO in a membrane electrode assembly

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National Science Review 2024年第2期11卷 94-95页

作者： Alexis t.Bell Department of Chemical and Biomolecular Engineering University of California

the electrochemical reduction of the CO2reaction （CO2RR） offers an attractive means for converting the carbon content of CO2, released from a stationary source or the atmosphere, into fuels and chemicals [1]. Utiliz...

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A deep neural network based surrogate model for damage identification in full-scale structures with incomplete noisy measurements

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Frontiers of Structural and Civil Engineering 2024年第3期18卷 393-410页

作者： tram BUI-NGOC Duy-Khuong LY tam t tRUONG Chanachai tHONGCHOM t.NGUYEN-tHOI Laboratory for Computational Mechanics Institute for Computational Science and Artificial IntelligenceVan Lang UniversityHo Chi Minh City 70000Vietnam Faculty of Mechanical-Electrical and Computer Engineering School of TechnologyVan Lang UniversityHo Chi Minh City 70000Vietnam Faculty of Civil Engineering School of TechnologyVan Lang UniversityHo Chi Minh City 70000Vietnam Department of Computer Science Aarhus UniversityAarhus 8000Denmark thammasat University research unit in structural and foundation engineering Department of Civil EngineeringThammasat UniversityPathumthani 12120Thailand Laboratory for Applied and Industrial Mathematics Institute for Computational Science and Artificial IntelligenceVan Lang UniversityHo Chi Minh City 70000Vietnam thammasat School of Engineering Thammasat UniversityPathumthani 12120Thailand

the paper introduces a novel approach for detecting structural damage in full-scale structures using surrogate models generated from incomplete modal data and deep neural networks(DNNs).A significant challenge in this field is the limited availability of measurement data for full-scale structures,which is addressed in this paper by generating data sets using a reduced finite element(FE)model constructed by SAP2000 software and the MAtLAB programming *** surrogate models are trained using response data obtained from the monitored structure through a limited number of measurement *** proposed approach involves training a single surrogate model that can quickly predict the location and severity of damage for all potential *** achieve the most generalized surrogate model,the study explores different types of layers and hyperparameters of the training algorithm and employs state-of-the-art techniques to avoid overfitting and to accelerate the training *** approach’s effectiveness,efficiency,and applicability are demonstrated by two numerical *** study also verifies the robustness of the proposed approach on data sets with sparse and noisy measured ***,the proposed approach is a promising alternative to traditional approaches that rely on FE model updating and optimization algorithms,which can be computationally *** approach also shows potential for broader applications in structural damage detection.

关键词： vibration-based damage detection deep neural network full-scale structures finite element model updating noisy incomplete modal data

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肠道菌群影响宿主机体血糖和脂质水平

生物医学工程与临床 2018年第3期22卷 355-355页

作者： kuno t

据kuno t 2018年1月19日[SeiRep，2018，8（1）：1253-1253．]报道，日本熊本大学的研究人员通过研究阐明了肠道菌群的改变对机体糖分和脂质代谢的影响，结果发现，肠道菌群所产生的次级胆汁酸（secondary bile acids）能影响机体的血... 详细信息

据kuno t 2018年1月19日[SeiRep，2018，8（1）：1253-1253．]报道，日本熊本大学的研究人员通过研究阐明了肠道菌群的改变对机体糖分和脂质代谢的影响，结果发现，肠道菌群所产生的次级胆汁酸（secondary bile acids）能影响机体的血糖水平和脂质浓度，相关研究或能帮助研究人员开发出新型疗法，通过靶向作用产生次级胆汁酸的肠道菌群来治疗诸如糖尿病和血脂异常等代谢性疾病。

关键词：肠道菌群血糖水平脂质水平机体宿主代谢性疾病脂质代谢研究人员

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