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Outcomes and efficacy of magnetic resonance imaging-compatible sacral nerve stimulator for management of fecal incontinence: A multi-institutional study

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World Journal of Radiology 2024年第2期16卷 32-39页

作者： Binit Katuwal Amy Thorsen kunal kochar Ryba Bhullar Ray King Ernesto Raul Drelichman Vijay K Mittal Jasneet Singh Bhullar Department of Surgery Ascension Providence HospitalMichigan State University College of Human MedicineSouthfieldMI 48075United States Department of Colon and Rectal surgery Alina Health Abbott Northwestern HospitalMinneapolisMN 55407United States Colon and Rectal Surgery Advocate Illinois MasonicPark RidgeIL 60068United States Volunteer Student Department of ResearchAscension Providence HospitalSouthfieldMI 48075United States Colon and Rectal Surgery University of WisconsinMadisonWI 53715United States General and Colorectal Surgery Ascension Providence HospitalMichigan State University College of Human MedicineSouthfieldMI 48075United States Department of Surgery Department of Medical EducationAscension Providence HospitalMichigan State University College of Human MedicineSouthfieldMI 48075United States

BACKGROUND Fecal incontinence(FI)is an involuntary passage of fecal matter which can have a significant impact on a patient’s quality of *** modalities of treatment exist for *** nerve stimulation is a well-established treatment for *** the increased need of magnetic resonance imaging(MRI)for diagnostics,the In-terStim which was previously used in sacral nerve stimulation was limited by MRI *** MRI-compatible InterStim was approved by the United States Food and Drug Administration in August 2020 and has been widely *** To evaluate the efficacy,outcomes and complications of the MRI-compatible *** Data of patients who underwent MRI-compatible Medtronic InterStim placement at UPMC Williamsport,University of Minnesota,Advocate Lutheran General Hospital,and University of Wisconsin-Madison was pooled and *** demographics,clinical features,surgical techniques,complications,and outcomes were *** the Reporting of Observational studies in Epidemiology(STROBE)cross-sectional reporting guidelines were *** Seventy-three patients had the InterStim *** mean age was 63.29±12.2 ***-seven(78.1%)patients were females and forty-two(57.5%)patients had *** addition to incontinence,overlapping symptoms included diarrhea(23.3%),fecal urgency(58.9%),and urinary incontinence(28.8%).Fifteen(20.5%)patients underwent Peripheral Nerve Evaluation before proceeding to definite implant ***-two(43.8%)patients underwent rechargeable InterStim ***(4.1%)patients needed removal of the *** of the external lead connection was observed in 7(9.6%)patients after the stage I *** explanation for one patient was due to ***(9.6%)patients had other complications like nerve pain,hematoma,infection,lead fracture,and *** mean follow-up was 6.62±3.5 ***-eight(93.2%)patients reported significant improvement of symptoms on

关键词： Fecal incontinence Sacral nerve stimulation InterStim Magnetic resonance imaging Sacral neuromodulation

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Synthesis and Characterization of UV Oligomer based on Cardanol

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Journal of Renewable Materials 2020年第1期8卷 57-68页

作者： kunal Wazarkar Anagha Sabnis Department of Polymer and Surface Engineering Institute of Chemical TechnologyMatungaMumbai-400019India

In the present research,cardanol based di-acrylic UV oligomer was synthesized by thiol-ene coupling followed by ring opening reaction with glycidyl *** intermediate as well as final diacrylate materials were analyzed by chemical as well as spectroscopic ***,ultraviolet(UV)radiation curable formulations were prepared by replacing commercial epoxy acrylate with synthesized UV oligomer in 10-50 wt%and applied on wood *** coated films were then evaluated for their optical,mechanical,chemical and thermal *** showed that up to 30 wt%amount of UVoligomer the coatings exhibited at par mechanical and chemical *** stain resistance of all the coatings was observed to be excellent.

关键词： Cardanol UVoligomer renewable radiation curable sustainable

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Development of Cardanol-Based Polyol via Click Chemistry and Crosslinking with Melamine Formaldehyde Resin for Coating Applications

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Journal of Renewable Materials 2018年第4期6卷 438-449页

作者： kunal Wazarkar Anagha Sabnis Department of Polymer and Surface Engineering Institute of Chemical TechnologyNathalal Parekh MargMatunga(E)Mumbai 400019India

The research work presented in this article deals with the synthesis of cardanol-based polyol and its curing with hexabutoxymethyl melamine(HBMM)for application in ***-based polyol was prepared via thiol-ene click reaction using *** present in the long chain of cardanol was successfully utilized to synthesize polyol via thiol-ene *** reaction was carried out between cardanol and thioglycerol in the presence of Irgacure 184(photoinitiator)and 1,8-Diazabicyclo[5.4.0]undec-7-ene(catalyst)under UV light for 12 h at 80°*** completion of the reaction,one mole of thioglycerol was successfully added across the double bond of a fatty chain of cardanol and confirmed by Fourier transform infrared spectroscopy(FTIR)and proton nuclear magnetic resonance spectroscopy and hydroxyl and iodine values were ***,the polyol thus prepared was cured with commercial HBMM in various proportions,such as 1:0.6,1:0.8 and 1:1,on an equivalent *** coatings were then characterized for mechanical,chemical,optical,thermal and anticorrosive *** was observed that coatings exhibited excellent performance properties as compared to that of its acrylic counterpart.

关键词： CNSL click chemistry HBMM crosslinker anticorrosive sustainable

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Scientific analysis of indigenous techniques for guggal(Commiphora wightii) tapping in India

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Journal of Forestry Research 2014年第3期25卷 695-700页

作者： Jatindra Nath Samanta kunal Mandla Directorate of Medicinal & Aromatic Plants Research Borivai Anand Gujarat–387310 India Directorate Mushroom Research Chambaghat Solan – 173213 India

Guggal, a threatened species that is endemic to western India, is tapped to extract medicinally important oleo-gum-resin （guggul）. However, the plant dies after gum exudation. The indigenous tapping techniques used by local people were examined in Gujarat, India to dis-cover the scientific basis behind these techniques： selection of gum in-ducer, season of tapping, and plant parts to be tapped. First, the presence of Xanthomonas axonopodis pv. commiphorae （Xac） in the gum suspen-sion used for tapping was established. This bacterium induces gum ooz-ing from the tapped plants and later, causes them to die off. The popula-tion of Xac in gum was found to decrease with the age of the gum. With that, fresh gum increased the tapping success. Second, local people pre-ferred tapping during the warm season, which we validated by determin-ing that Xac growth was best at 30 ＆#176;C. Tapping during September （mean temperature 25.7-30.0 ＆#176;C） clearly favoured growth of the pathogen and yielded maximum guggul. Multiple tapping on a mature tree ensured maximum gum extraction before its death. Finally, application of in-digenous technology under natural plant stands by the local people en-sured availability of this important raw drug for consumption. Our study established that the age-old traditional methods have a strong scientific basis. However, it is imperative to formulate strategies based on con-temporary scientific understanding to protect this natural resource before it becomes extinct.

关键词： Burseraceae gummosis medicinal plant participatory forest management xerophytes

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Spectral indices measured with proximal sensing using canopy reflectance sensor,chlorophyll meter and leaf color chart for in-season grain yield prediction of basmati rice

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Pedosphere 2022年第6期32卷 812-822页

作者： VARINDERPAL-SINGH kunal MEHTAB-SINGH BIJAY-SINGH Department of Soil Science Punjab Agricultural UniversityLudhiana 141004(India) Shree Guru Gobind Singh Tricentenary(SGT)University Chandu-Budhera RoadGurugramHaryana 122505(India) College of Agriculture Punjab Agricultural UniversityLudhiana 141004(India)

A number of optical sensing tools are now available and can potentially be used for refining need-based fertilizer nitrogen(N)topdressing *** for estimating field-specific fertilizer N needs are based on predictions of yield made while the crops are still growing in the *** present study was conducted to establish and validate yield prediction models using spectral indices measured with proximal sensing using GreenSeeker canopy reflectance sensor,soil and plant analyzer development(SPAD)chlorophyll meter,and two different types of leaf color charts(LCCs)for five basmati rice genotypes across different growth *** analysis was performed using normalized difference vegetation index(NDVI)recorded with GreenSeeker sensor and leaf greenness indices measured with SPAD meter and LCCs developed by Punjab Agricultural University,Ludhiana(India)(PAU-LCC)and the International Rice Research Institute,Philippines(IRRI-LCC).The exponential relationship between NDVI and grain yield exhibited the highest coefficient of determination(R^(2))and minimum normalized root mean square error(NRMSE)at panicle initiation stage and explained 38.3%–76.4%variation in yield using genotype-specific *** indices pooled for different genotypes were closely related to grain yield at all growth stages and explained53.4%–57.2%variation in grain *** different spectral indices with cumulative growing degree days(CGDD)decreased the accuracy of yield *** with days after transplanting(DAT),however,did not reduce or improve the predictability of *** ability of each model to predict grain yield was validated with an independent dataset collected from two experiments conducted at different sites with a range of fertilizer N *** NDVI-based genotype-specific models exhibited a robust linear correlation(R^(2)=0.77,NRMSE=7.37%,n=180)between observed and predicted grain yields only at 35 DAT(i.e.,panicle initiation stage)

关键词： GreenSeeker canopy reflectance sensor IRRI-LCC need-based nutrient management nitrogen optical sensing tools PAU-LCC SPAD meter

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Cardanol-Based Polyurethane Coatings via Click Chemistry:An Eco-friendly Approach

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Journal of Renewable Materials 2018年第5期6卷 517-528页

作者： kunal Wazarkar Anagha Sabnis Department of Polymer and Surface Engineering Institute of Chemical TechnologyNathalal Parekh MargMatunga(E)Mumbai-400019India

This research work discloses the preparation of polyurethane coatings from cardanol modified using thiolene chemistry,wherein unsaturated long alkyl chain of cardanol was successfully utilized via thiol-ene click reaction to synthesize *** this purpose,cardanol and thioglycerol was reacted in the presence of Irgacure 184(photoinitiator)and 1,8-Diazabicyclo[5.4.0]undec-7-ene(catalyst)and exposed to UV light for 12 h at 80℃.One mole of thioglycerol was successfully added across the double bond of fatty chain of cardanol and confirmed by chemical and spectroscopic ***,the polyol thus prepared was cured with various polyisocyanates,viz.,N-75(HDI based),L-67/BA(TDI based),Z-4470(IPDI based)and corresponding polyurethane coatings were *** coatings were then analyzed for mechanical,chemical,optical,thermal and anticorrosive *** was observed that cardanol-based PU coatings exhibited excellent mechanical,chemical and thermal and anticorrosive properties as compared to that of commercial acrylic-PU coatings.

关键词： Thiol-ene click chemistry polyurethane anticorrosive ultraviolet light

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EPQ model with the effect of inflation and reliability for partial trade credit under fuzzy and cloudy fuzzy environment

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Journal of Management Analytics 2024年第1期11卷 110-134页

作者： Supriya Tiwari kunal Shah Kajal Bhimani Department of Science and Humanities Apollo Institute of Engineering&TechnologyGTUAhmedabadIndia Department of Mathematics SMMPISRKadi Sarva VishwavidyalayaGandhinagarIndia AVAerials 401 Swarnim Business Hub-1 New Chamunda SocietyGodrej Garden CityGotaAhmedabadIndia

The proposed study offers the first-of-its-kind economic production quantity model for deteriorating items having a demand rate to be price dependent under the effect of inflation and reliability with partial trade *** model is extended under an uncertain environment by assuming inventory parameters to be triangular fuzzy numbers and cloudy triangular fuzzy *** objective of the study is to maximize the profit of the inventory system and to identify the most suitable environment for the proposed *** are verified using the numerical ***,the comparative study is presented to justify the nature of fuzzy and cloudy fuzzy *** analysis under all environments is conducted to identify the most sensitive parameters of all.

关键词： EPQ partial trade credit inflation reliability triangular fuzzy number cloudy triangular fuzzy number

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Real-Time Analysis of COVID-19 Pandemic on Most Populated Countries Worldwide

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Computer Modeling in Engineering & Sciences 2020年第12期125卷 943-965页

作者： Meenu Gupta Rachna Jain Akash Gupta kunal Jain Department of Computer Science and Engineering Chandigarh UniversityPunjab140301India Department of Computer Science and Engineering Bharati Vidyapeeth’s College of EngineeringNew Delhi110063India

The spread of the Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2)has already taken on pandemic extents,influencing even more than 200 nations in a couple of ***,regulation measures in China have decreased new cases by over 98%,this decrease is not the situation everywhere,and most of the countries still have been affected by *** objective of this research work is to make a comparative analysis of the top 5 most populated countries namely United States,India,China,Pakistan and Indonesia,from 1st January 2020 to 31st July *** research work also targets to predict an increase in the number of deaths and total infected cases in these five *** our research,the performance of the proposed framework is determined by using three Machine Learning(ML)regression algorithms namely Linear Regression(LR),Support Vector Regression(SVR),andRandom Forest(RF)*** proposed model is also validated upon the infected and death cases of further *** performance of these three algorithms is compared using the RootMean Square Error(RMSE)*** Forest algorithm shows best performance as compared to other proposed algorithms,with the lowest RMSE value in the prediction of total infected and total deaths cases for all the top five most populated countries.

关键词： COVID-19 SARS COV-2 country-wise analysis most populated countries pandemic mortality rate

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Utilization of residual fatty acids in matter organic non-glycerol from a soy biodiesel plant in filaments used for 3D printing

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Journal of Bioresources and Bioproducts 2023年第3期8卷 215-223页

作者： Sreesha Malayil Athira Nair Surendran kunal Kate Jagannadh Satyavolu Conn Center for Renewable Energy Research University of LouisvilleLouisville 40292KYUSA Materials Innovation Guild Department of Mechanical EngineeringUniversity of LouisvilleLouisville 40292KYUSA

Matter organic non-glycerol(MONG)is a considerable waste output(20%−25%of crude glyc-erol)typically landfilled by soy biodiesel *** this work,soy MONG was characterized for potential use as a copolymer to produce filaments for 3D printing with an intent to add value and redirect it from *** a copolymer,MONG was evaluated to reduce the synthetic polymer content of the natural fiber composites(NFC).Even though the general thermal behavior of the MONG was compared to that of a thermoplastic polymer in composite applications,it is depen-dent on the composition of the MONG,which is a variable depending on plant discharge *** order to improve the thermal stability of MONG,we evaluated two pretreatments(acid and acid+peroxide).The acid+peroxide pretreatment resulted in a stabilized paste with decreased soap content,increased crystallinity,low molecular weight small chain fatty acids,and a sta-ble blend as a copolymer with a thermoplastic *** treatment increased formic acid(17.53%)in MONG,along with hydrogen peroxide,led to epoxidation exhibited by the increased concentration of oxirane(5.6%)evaluating treated MONG as a copolymer in polymer processing and 3D printing.

关键词： Matter organic non-glycerol Soy biodiesel waste Polymer composite Epoxidation Soap splitting Fatty acid

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Machine learning sparse tight-binding parameters for defects

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npj Computational Materials 2022年第1期8卷 1081-1091页

作者： Christoph Schattauer Milica Todorović kunal Ghosh Patrick Rinke Florian Libisch Institute for Theoretical Physics TU Wien1040ViennaAustria Department of Applied Physics Aalto UniversityP.O.Box 11100AaltoFI-00076Finland Department of Mechanical and Materials Engineering University of TurkuFI-20014TurkuFinland Department of Information and Computer Science Aalto UniversityP.O.Box 15400AaltoFI-00076Finland

We employ machine learning to derive tight-binding parametrizations for the electronic structure of *** test several machine learning methods that map the atomic and electronic structure of a defect onto a sparse tight-binding *** Multi-layer perceptrons(i.e.,feed-forward neural networks)perform best we adopt them for our further *** demonstrate the accuracy of our parameterizations for a range of important electronic structure properties such as band structure,local density of states,transport and level spacing simulations for two common defects in single layer *** machine learning approach achieves results comparable to maximally localized Wannier functions(i.e.,DFT accuracy)without prior knowledge about the electronic structure of the defects while also allowing for a reduced interaction range which substantially reduces calculation *** is general and can be applied to a wide range of other materials,enabling accurate large-scale simulations of material properties in the presence of different defects.

关键词： structure electronic spacing

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