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Epidemiology and outcome of individuals with intraductal papillary neoplasms of the bile duct

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World Journal of Gastrointestinal Oncology 2023年第5期15卷 843-858页

作者： Rong-Shou Wu Wen-Jun Liao Jing-Sheng Ma jia-kun Wang Lin-Quan Wu Ping Hou Department of Hepatobiliary and Pancreatic Surgery The Second Affiliated Hospital of Nanchang UniversityNanchang 330000Jiangxi ProvinceChina Department of Organ Transplantation The Second Affiliated Hospital of Nanchang UniversityNanchang 330000Jiangxi ProvinceChina Department of General Surgery The First Affiliated Hospital of Gannan Medical CollegeNo.23 Qingnian RoadZhanggong DistrictGanzhou 341000Jiangxi ProvinceChina

BACKGROUND Intraductal papillary neoplasm of the bile duct(IPNB)is a rare distinct subtype of precursor lesions of biliary *** is considered to originate from luminal biliary epithelial cells,typically displays mucin-hypersecretion or a papillary growth pattern,and results in cystic dilatation[1].IPNB develops anywhere in the intrahepatic and extrahepatic biliary tracts,and can occur in various pathological stages from low-grade dysplasia to invasive *** have similar phenotypic changes in the occurrence and development of all subtypes,and the prognosis is significantly better than that of traditional(nonpapillary)*** To evaluate the clinicopathological features of IPNB to provide evidence-based guidance for *** Invasive IPNB,invasive intraductal papillary mucinous neoplasm of the pancreas(IPMN),and traditional cholangiocarcinoma data for affected individuals from 1975 to 2016 were obtained from the Surveillance,Epidemiology,and End Results(SEER)*** percentage changes(APCs)in the incidence and incidence-based(IB)mortality were *** identified the independent predictors of overall survival(OS)and cancer-specific survival(CSS)in indivi duals with invasive *** The incidence and IB mortality of invasive IPNB showed sustained decreases,with an APC of-4.5%(95%CI:-5.1%to-3.8%)and-3.3%(95%CI:-4.1%to-2.6%)(P<0.001),*** decreases in incidence and IB mortality were seen for invasive IPMN but not for traditional *** OS and CSS for invasive IPNB were better than for invasive IPMN and traditional cholangiocarcinoma.A total of 1635 individuals with invasive IPNB were included in our prognosis *** most common tumor sites were the pancreaticobiliary ampulla(47.9%)and perihilar tract(36.7%),but the mucin-related subtype of invasive IPNB was the main type,intrahepatically(approximately 90%).In the univariate and multivariate Cox regression analysis,age,tum

关键词： Surveillance,Epidemiology,and End Results database Intraductal papillary neoplasms of the bile duct Subtype Annual percentage changes Prognosis

A quasi-distributed dynamic and static strain sensor system

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Optoelectronics Letters 2008年第4期4卷 243-247页

作者： JING Wen-cai LIU Tao ZHANG Pei-song LIU kun jia Da-gong ZHANG Yi-mo College of Precision Instrument ＆ Optoelectronics Engineering Key Laboratory for Optoelectronic Information and Technical Science of Ministry of Education Tianjin Universiey Tianjin 300072 China

A quasi-distributed dynamic and static strain sensor system consisting of 16 FBG sensors is designed by using an amplified-sponteneous emission （ASE） optical source, an optical tunable falter and a tunable laser. Aresolution of about 5 με has been achieved for dynamic strain measurement. The resolution for static strain measurement is about 1 με.

关键词：静应力传感器系统准分布式动力学光纤布拉格光栅光源

Highly Stretchable and Transparent Ionic Conductor with Novel Hydrophobicity and Extreme-Temperature Tolerance

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Research 2020年第1期2020卷 363-372页

作者： Lei Shi kun jia Yiyang Gao Hua Yang Yaming Ma Shiyao Lu Guoxin Gao Huaitian Bu Tongqing Lu Shujiang Ding Department of Applied Chemistry School of ScienceXi’an Key Laboratory of Sustainable Energy Materials ChemistryMOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed MatterState Key Laboratory of Electrical Insulation and Power EquipmentXi’an Jiaotong UniversityXi’an 710049China State Key Laboratory for Strength and Vibration of Mechanical Structure School of Aerospace EngineeringXi’an Jiaotong UniversityXi’an 710049China SINTEF Industry Forskningsvei 10373 OsloNorway

Highly stretchable and transparent ionic conducting materials have enabled new concepts of electronic devices denoted as iontronics,with a distinguishable working mechanism and performances from the conventional ***,the existing ionic conducting materials can hardly bear the humidity and temperature change of our daily life,which has greatly hindered the development and real-world application of ***,we design an ion gel possessing unique traits of hydrophobicity,humidity insensitivity,wide working temperature range(exceeding 100℃,and the range covered our daily life temperature),high conductivity(10^(-3)~10^(-5) S/cm),extensive stretchability,and high transparency,which is among the bestperforming ionic conductors ever developed for flexible *** ion gel-based iontronics have been demonstrated,including large-deformation sensors,electroluminescent devices,and ionic cables,which can serve for a long time under harsh *** designed material opens new potential for the real-world application progress of iontronics.

关键词： Highly humidity exceeding

The comparison of survival between active surveillance or watchful waiting and focal laser ablation in patients with low-risk prostate cancer

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Asian Journal of Andrology 2022年第5期24卷 494-499页

作者： jia-kun Li Chi-Chen Zhang Shi Qiu kun Jin Bo-Yu Cai Qi-Ming Yuan Xing-Yu Xiong Lian-Sha Tang Di Jin Xiang-Hong Zhou Yi-Ge Bao Lu Yang Qiang Wei Department of Urology Institute of UrologyWest China Hospital of Sichuan UniversityChengdu 610041China Department of Biotherapy Cancer CenterWest China Hospital of Sichuan UniversityChengdu 610041China

Prostate cancer(PCa)is the second-most common cancer among *** active surveillance or watchful waiting(AS/WW)and focal laser ablation(FLA)can avoid the complications caused by radical *** to make the choice between these options in clinical practice needs further ***,this study aims to compare and analyze their effects based on overall survival(OS)and cancer-specific survival(CSS)to obtain better long-term *** included patients with low-risk PCa from the Surveillance Epidemiology and End Results database of 2010–*** Cox proportional hazard analyses were conducted for OS and CSS in the two *** eliminate bias,this study applied a series of sensitivity ***,Kaplan–Meier curves were plotted to obtain survival status.A total of 18841 patients with low-risk PCa were included,with a median of 36-month *** to the multivariate Cox proportional hazard regression,the FLA group presented inferior survival benefits in OS than the AS/WW group(hazard ratio[HR]:2.13,95%confidence interval[CI]:1.37–3.33,P<0.05).After adjusting for confounders,the result persisted(HR:1.69,95%CI:1.02–2.81,P<0.05).According to the results of the sensitivity analysis,the inverse probability of the treatment weighing model indicated the same result in *** conclusion,AS/WW and FLA have the advantage of fewer side effects and the benefit of avoiding overtreatment compared with standard *** study suggested that AS/WW provides more survival benefits for patients with low-risk *** relevant researches and data will be needed for further clarity.

关键词： active surveillance cancer-specific survival focal laser ablation low-risk prostate cancer overall survival watchful waiting

Thermal-Fluid-Structure Coupling Analysis of Flexible Corrugated Cryogenic Hose

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China Ocean Engineering 2022年第4期36卷 658-665页

作者： YANG Liang LIU Miao-er LIU Yun LI Fang-qiu FAN jia-kun LIU Fu-peng LU Zhao-kuan YANG jian-ye YAN Jun CNOOC Gas&Power Group Co. Ltd.Beijing 100028China CNOOC Research Institute Co. Ltd.Beijing 100028China Offshore Oil Engineering Co. Ltd.Tianjin 300461China Ningbo Institute of Dalian University of Technology Ningbo 315016China State Key Laboratory of Structural Analysis for Industrial Equipment Department of Engineering MechanicsInter-national Research Center for Computational MechanicsDalian University of TechnologyDalian 116024China

This work presents a numerical investigation of the thermal–fluid–structure coupling behavior of the liquid natural gas(LNG)transported in the flexible corrugated cryogenic hose.A three-dimensional model of the corrugated hose structure composed of multiple layers of different materials is established and coupled with turbulent LNG flow and heat transfer models in the commercial software ANSYS *** flow transport behavior,heat transfer across the hose layers,and structural response caused by the flow are *** studies are performed to evaluate the impacts of inlet flow rate and thermal conductivity of insulation material on the temperature and structural stress of the corrugated *** study found that,compared with a regular operating condition,higher inlet flow velocities not only suppress the heat gain of the LNG but also lower the flow-induced structural *** insulation layer exhibits excellent performance in maintaining the temperature at the fluid–structure interface,showing little temperature change with respect to material thermal conductivity and ambient *** simulation results may contribute to the research and design of the flexible corrugated cryogenic hoses and provide guidance for safer and more efficient field operations.

关键词： flexible corrugated cryogenic hose LNG computational fluid dynamics thermal–fluid–structure coupling

Optical demonstration of quantum fault-tolerant threshold

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Light(Science & Applications) 2022年第8期11卷 1834-1842页

作者： Kai Sun Ze-Yan Hao Yan Wang jia-kun Li Xiao-Ye Xu Jin-Shi Xu Yong-jian Han Chuan-Feng Li Guang-Can Guo CAS Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei230026China CAS Center for Excellence in Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei230026China Hefei National Laboratory University of Science and Technology of ChinaHefei230088China

A major challenge in practical quantum computation is the ineludible errors caused by the interaction of quantum systems with their environment. Fault-tolerant schemes, in which logical qubits are encoded by several physical qubits, enable to the output of a higher probability of correct logical qubits under the presence of errors. However, strict requirements to encode qubits and operators render the implementation of a full fault-tolerant computation challenging even for the achievable noisy intermediate-scale quantum technology. Especially the threshold for fault-tolerant computation still lacks experimental verification. Here, based on an all-optical setup, we experimentally demonstrate the existence of the threshold for the fault-tolerant protocol. Four physical qubits are represented as the spatial modes of two entangled photons, which are used to encode two logical qubits. The experimental results clearly show that when the error rate is below the threshold, the probability of correct output in the circuit, formed with fault-tolerant gates, is higher than that in the corresponding non-encoded circuit. In contrast, when the error rate is above the threshold, no advantage is observed in the fault-tolerant implementation. The developed high-accuracy optical system may provide a reliable platform to investigate error propagation in more complex circuits with fault-tolerant gates.

关键词： quantum error operators

Multifactor analysis of the technique in total laparoscopic gastric cancer

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World Journal of Gastrointestinal Surgery 2023年第9期15卷 2003-2011页

作者： jia-kun Shi Bo Wang Xin-Sheng Zhang Pin Lv Yun-Long Chen Shuang-Yi Ren Department of Gastrointestinal Surgery Dalian Friendship HospitalDalian 116000Liaoning ProvinceChina Department of Gastrointestinal Surgery The Second Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina

BACKGROUND Esophageal gastric anastomosis is a common surgical technique used to treat patients with gastric cancer who undergo total ***,using simple anastomosis techniques alone may not meet the needs of patients in some cases and can lead to complications such as anastomotic stenosis and *** order to overcome these issues and improve patient prognosis,muscle flap reconstruction technique has *** flap reconstruction is a method of improving gastric-esophageal anastomosis by transplanting muscle *** covering the anastomotic site with muscle tissue,it not only enhances the stability of the anastomosis site but also increases blood supply,promoting healing and recovery of the ***,the use of muscle flap reconstruction technique in esophageal gastric anastomosis during total gastrectomy for gastric cancer is increasingly widely *** To determine the effectiveness of esophagogastric anastomosis using the muscle flap reconstruction technology in total abdominal gastrectomy for gastric cancer and perform follow-up experiments to understand the factors affecting patients’*** The study subjects were 60 patients with gastric cancer who were admitted to our hospital between October 2018 and January *** patients underwent esopha-gogastric anastomosis using the double muscle flap reconstruction technology in total abdominal *** indicators were determined,and INTRODUCTION Gastric cancer is one of the most common tumors of the digestive system *** gastric cancer may not have significant manifestations in the early stage,as the disease progresses,systemic symptoms such as emaciation,anemia,and gastric perforation are observed[1].Surgery is the main treatment strategy for gastric *** recent advances in total laparoscopy,total laparoscopic radical resection has gradually become an important treatment strategy for gastric *** laparoscopic

关键词： Esophagogastric anastomotic muscle flap reconstruction technique Total abdominal radical gastrectomy for gastric cancer Gastric cancer Perioperative indicators Prognosis Pathological parameters

China-Russia Friendship Continued and Promoted

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China & The World Cultural Exchange 2009年第8期75卷 22-25页

作者： staff reporter jia kun

The year 2009 is a significant year that marks the 60^th anniversary of the People＇s Republic of China and the 60^th anniversary Of China-Russia diplomatic ties. Shategic partnership that is mature, stable and sound has common strategic pursuits in the complicated and changing context of international relations While celebrating the 60^th anniversary of diplomatic ties, China and Russia vowed to be always good partners, good neighbors and good friends. Both world peace and stability.

关键词：中国俄罗斯文化交流友谊

An Exhibition of Carved Stone Piers to Welcome Chinese New Year

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China & The World Cultural Exchange 2009年第3期75卷 32-35页

作者： jia kun & cao lijun

From January 24 to February 14, 2009, an exhibition oncarved stone piers from Beijing and Tianjin was held in Beijing International Sculpture Park, displaying nearly 300 pairs of traditional carved stone piers of the ... 详细信息

关键词：石刻图片展览桥墩民间传统码头博物馆清王朝摄影师