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Bazi Bushen alleviates reproductive aging in aged male mice

Chinese Journal of Natural Medicines 2024年第05期 416-425页

作者： ma kun LI Mengnan SONG Yahui maO Xinjing ZHANG Shaolan ZHANG Yaping JIANG Yuning JI Chuanyuan NIU kunxu LI Hongrong HOU Yunlong WEI Cong Graduate School Hebei University of Chinese Medicine State Key Laboratory for Innovation and Transformation of Luobing Theory Key Laboratory of State Administration of TCM (Cardio-Cerebral Vessel Collateral Disease) College of Traditional Chinese Medicine·College of Integrated Traditional Chinese and Western Medicine Nanjing University of Chinese Medicine Hebei Provincial Key Laboratory of Luobing Key Disciplines of State Administration of TCM for Luobing

Bazi Bushen（BZBS）, a traditional Chinese medicine（TCM）, has demonstrated therapeutic efficacy in testicular dysfunction within D-galactose and NaNO2mouse models. This study aimed to ascertain if BZBS could also mitigate the decline in testicular function associated with natural aging. Therefore, male aged mice were employed to evaluate the preventive effects of BZBS on male reproductive aging. This was achieved by assessing sex hormone production, testicular histomorphology, and *** to the untreated aged control group, BZBS administration elevated the levels of sex hormones and spermatocyte populations and preserved normal testicular structure in aged mice. Notably, spermatogenesis was maintained. Further analyses, including malondialdehyde（MDA） assays and real-time PCR, indicated that BZBS diminished testicular oxidative stress and the inflammatory *** these findings, mice treated with BZBS exhibited reductions in the populations of senescent and apoptotic cells within the seminiferous tubules, suggesting alleviated cellular damage. In contrast, we observed that rapamycin, a drug known for its longevity benefits, induced excessive testicular apoptosis and did not decrease lipid peroxidation. Collectively, our results highlight BZBS's promising clinical potential in counteracting male reproductive aging, underlining its mechanisms of action.

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Novel wood-plastic composite fabricated via modified steel slag:Preparation,mechanical and flammability properties

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International Journal of Minerals,Metallurgy and materials 2024年第9期31卷 2110-2120页

作者： ling Zhao Kai Zhao Zhenwei Shen Yifan Wang Xiaojie Xia Hao Zhang Hongming Long School of Metallurgical Engineering Anhui University of TechnologyMa’anshan 243032China School of Civil Engineering and Architecture Anhui University of TechnologyMa’anshan 243032China School of materials Science and Engineering Anhui University of TechnologyMa’anshan 243032China Key Laboratory of Metallurgical Emission Reduction and Resources Recycling(Anhui University of Technology) Ministry of EducationMa’anshan 243002China

A novel method was developed to enhance the utilization rate of steel slag(SS).Through treatment of SS with phosphoric acid and aminopropyl triethoxysilane(KH550),we obtained modified SS(MSS),which was used to prepare MSS/wood-plastic composites(MSS/WPCs)by replacing talcum powder(TP).The composites were fabricated through melting blending and hot *** mechanical and combustion properties,which comprise heat release,smoke release,and thermal stability,were systematically *** can improve the mechanical strength of the composites through grafting reactions between wood powder and ***,MSS/WPC#50(16wt%MSS)with an MSS-to-TP mass ratio of 1:1 exhibited optimal comprehensive *** with those of WPC#0 without MSS,the tensile,flexural,and impact strengths of MSS/WPC#50 were increased by 18.5%,12.8%,and 18.0%,***,the MSS/WPC#50 sample achieved the highest limited oxygen index of 22.5%,the highest vertical burning rating at the V-1 level,and the lowest horizontal burning rate at 44.2 mm/*** formation of a dense and stable char layer led to improved thermal stability and a considerable reduction in heat and smoke releases of MSS/WPC#***,the partial replacement of TP with MSS slightly compromised the mechanical and flame-retardant properties,possibly due to the weak grafting caused by SS powder *** findings suggest the suitability of MSS/WPCs for high-value-added applications as decorative panels indoors or outdoors.

关键词： modified steel slag wood–plastic composites preparation method mechanical property flame retardant

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基于Holland台风模型及三重嵌套海浪模式的台风浪数值模拟研究

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海洋与湖沼 2024年第1期55卷 51-64页

作者：马秀玲魏来中国海洋大学三亚海洋研究院海南三亚572024

现有的风场资料存在台风中心附近风速偏低的问题。为改进台风期间风场数据,使用Holland经验台风模型结合多平台交叉校准数据(cross-calibrated multi-platform,CCMP)及欧洲中期天气预报中心的再分析数据(European Centre for Medium-ran... 详细信息

现有的风场资料存在台风中心附近风速偏低的问题。为改进台风期间风场数据,使用Holland经验台风模型结合多平台交叉校准数据(cross-calibrated multi-platform,CCMP)及欧洲中期天气预报中心的再分析数据(European Centre for Medium-range Weather Forecasts Reanalysis data,ERA5)风场资料,研究了不同台风最大风速半径(maximum wind radius of the typhoon,RMW)、Holland B参数对模拟效果的影响,确定了最优模拟参数,并以改进后的风场驱动三重嵌套海浪模型对台风“威马逊”发生期间的台风浪进行模拟。模拟结果与实测数据对比表明,(1)改进的风场资料与实测结果更为接近,作为海浪模式驱动项可更好地模拟台风期间波浪状况;(2)三重嵌套海浪模型的波浪模拟效果优于单独的海浪模型。

关键词： Holland台风模型台风“威马逊” 台风浪海浪数值模拟

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RuCo alloy nanoparticles embedded within N-doped porous two-dimensional carbon nanosheets:a high-performance hydrogen evolution reaction catalyst

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Tungsten 2024年第1期6卷 114-123页

作者： Jin-Hui Wang Shao-Wei Yang Fu-Bin ma Yi-Ke Zhao Shi-Nuo Zhao Zheng-Yu Xiong Dong Cai Hai-Dong Shen Kai Zhu Qiu-Yu Zhang Yue-ling Cao Tian-Shuai Wang He-Peng Zhang Research and Development Institute of Northwestern Polytechnical University in Shenzhen Shenzhen 518057China Xi’an Key Laboratory of Functional Organic Porous materials School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’an 710129China School of Power and Energy Northwestern Polytechnical UniversityXi’an 710129China Chongqing Science and Technology Innovation Center of Northwestern Polytechnical University Chongqing 401135China

Developing cost-effective electrocatalysts with high activity and stability especially at high current density is of great significance for the large-scale commercial application of electrochemical water splitting to hydrogen production but still remains ***,we report an effective confinement pyrolysis strategy to fabricate embedded ruthenium-cobalt nanoclusters supported on N-doped porous two-dimensional carbon nanosheets(RuCo@CN).markedly,the embedded structure can effectively prevent the migration,agglomeration,and leaching of nanoparticles,thus endowing the RuCo@CN catalyst with high *** be exact,high stability with up to 650 h can be achieved at high current density(-500 and-1000 ma·cm^(-2)).Besides,the RuCo@CN catalysts also exhibit highly reactive with low overpotentials of only 11mV at-10 ma·cm^(-2).Density functional theory calculations reveal that the introduction of cobalt reduces the decomposition barrier of H_(2)O for RuCo@CN alloy,thus promoting hydrogen evolution reaction.

关键词： Hydrogen evolution reaction Confinement pyrolysis strategy Mosaic structure Stability

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A Novel Analysis Approach of Uniform Persistence for an Epidemic Model with Quarantine and Standard Incidence Rate

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Acta mathematicae Applicatae Sinica 2024年第3期40卷 695-707页

作者： Song-bai GUO Yu-ling XUE Xi-liang LI Zuo-huan ZHENG School of Science Beijing University of Civil Engineering and ArchitectureBeijing 102616China School of mathematics and Statistics Hainan Normal UniversityHaikou 571158China Academy of mathematics and Systems Science Chinese Academy of SciencesBeijing 100190China School of mathematics and Information Science Shandong Technology and Business UniversityYantai 264005China School of mathematical Sciences University of Chinese Academy of SciencesBeijing 100049China

Inspired by the transmission characteristics of the coronavirus disease 2019(COVID-19),an epidemic model with quarantine and standard incidence rate is first developed,then a novel analysis approach is proposed for finding the ultimate lower bound of the number of infected individuals,which means that the epidemic is uniformly persistent if the control reproduction number R_(c)>*** approach can be applied to the related biomat hem at ical models,and some existing works can be improved by using *** addition,the infection-free equilibrium V^(0)of the model is locally asymptotically stable(LAS)if R_(c)1.

关键词： uniform persistence epidemic model control reproduction number quarantine standard incidence rate

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Towards a new avenue for rapid synthesis of electrocatalytic electrodes via laser-induced hydrothermal reaction for water splitting

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International Journal of Extreme manufacturing 2024年第1期6卷 340-351页

作者： Yang Sha Menghui Zhu kun Huang Yang Zhang Francis Moissinac Zhizhou Zhang Dongxu Cheng Paul mativenga Zhu Liu Department of materials School of Natural SciencesThe University of ManchesterOxford RoadManchester M139PLUnited Kingdom Laser Processing Research Centre Department of MechanicalAerospace and Civil EngineeringSchool of EngineeringThe University of ManchesterOxford RoadManchester M139PLUnited Kingdom National Graphene Institute The University of ManchesterOxford RoadManchester M139PLUnited Kingdom Department of Chemical Engineering and Analytical Science School of EngineeringThe University of ManchesterOxford RoadManchester M139PLUnited Kingdom Research Centre for Laser Extreme manufacturing Ningbo Institute of Materials Engineering and TechnologyChinese Academy of SciencesNingboPeople’s Republic of China

Electrochemical production of hydrogen from water requires the development ofelectrocatalysts that are active,stable,and low-cost for water *** address these challenges,researchers are increasingly exploring binder-free electrocatalytic integratedelectrodes (IEs) as an alternative to conventional powder-based electrode preparation methods,for the former is highly desirable to improve the catalytic activity and long-term stability for large-scale applications of ***,we demonstrate a laser-inducedhydrothermal reaction (LIHR) technique to grow NiMoO4nanosheets on nickel foam,which is then calcined under H2/Ar mixed gases to prepare the IE *** electrode exhibits superior hydrogen evolution reaction performance,requiring overpotentials of 59,116 and143 mV to achieve current densities of 100,500 and 1000 ma·*** the 350 h chronopotentiometry test at current densities of 100 and 500 m A·cm-2,the overpotentialremains essentially *** addition,NiFe-layered double hydroxide grown on Ni foam is also fabricated with the same LIHR method and coupled with IE-NiMo-IR to achieve water *** combination exhibits excellent durability under industrial current *** energy consumption and production efficiency of the LIHR method are systematicallycompared with the conventional hydrothermal *** LIHR method significantly improves the production rate by over 19 times,while consuming only 27.78%of the total energy required by conventional hydrothermal methods to achieve the same production.

关键词： electrocatalytic electrode laser-induced hydrothermal reaction NiFe layered double hydroxides hydrogen evolution reaction water splitting energy consumption production rate

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Diagnostic efficacy of virtual organ computer-assisted analysis in measuring the volume ratio of subchorionic hematoma with serum progesterone

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World Journal of Clinical Cases 2024年第17期12卷 3053-3060页

作者： Lin-ling Shen Jing Shi Chang-Wei Ding Gao-Le Dai Qi ma Department of Ultrasound The Second Affiliated Hospital of Soochow UniversitySuzhou 215004Jiangsu ProvinceChina Department of Ultrasound Wuxi People’s Hospital of Nanjing Medical UniversityWuxi 211103Jiangsu ProvinceChina

BACKGROUND Subchorionic hematoma(SCH)is a common complication in early pregnancy characterized by the accumulation of blood between the uterine wall and the chorionic *** can lead to adverse pregnancy outcomes such as miscarriage,preterm birth,and other *** detection and accurate assessment of SCH are crucial for appropriate management and improved pregnancy *** To evaluate the diagnostic efficacy of virtual organ computer-assisted analysis(VOCAL)in measuring the volume ratio of SCH to gestational sac(GS)combined with serum progesterone on early pregnancy outcomes in patients with *** A total of 153 patients with SCH in their first-trimester pregnancies between 6 and 11 wk were *** patients were followed up until a gestational age of 20 *** parameters of transvaginal two-dimensional ultrasound,including the circumference of SCH(Cs),surface area of SCH(Ss),circumference of GS(Cg),and surface area of GS(Sg),and the parameters of VOCAL with transvaginal three-dimensional ultrasound,including the three-dimensional volume of SCH(3DVs)and GS(3DVg),were *** size of the SCH and its ratio to the GS size(Cs/Cg,Ss/Sg,3DVs/3DVg)were recorded and *** Compared with those in the normal pregnancy group,the adverse pregnancy group had higher Cs/Cg,Ss/Sg,and 3DVs/3DVg ratios(Pmance predicted adverse pregnancy outcomes,resulting in an AUC of 0.767,and the sensitivity,specificity were 70.2%,75%*** measuring 3DVs/3DVg combined with serum progesterone gave a diagnostic AUC of 0.824 for early pregnancy outcome in SCH patients,with a high sensitivity of 82.1%and a specificity of 72.1%,which showed a significant difference between *** VOCAL-measured 3DVs/3DVg effectively quantifies the severity of SCH,while combined serum progesterone better predicts adverse pregnancy outcomes.

关键词： Subchorionic hematoma Virtual organ computer-assisted analysis Gestational sac Serum progesterone Ultrasound parameters Adverse pregnancy outcomes

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Novel compound heterozygous mutations in the hemojuvelin gene in a juvenile hemochromatosis patient:A case report

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World Journal of Clinical Cases 2024年第19期12卷 3961-3970页

作者： ling-Ding Xie Xiao-Mu Kong Jing-Xia Shen Tai-ling Wang Jing ma Yun-Fen Zhang Xiao-Ping Chen Department of Endocrinology China-Japan Friendship HospitalBeijing 100029China Department of Tumor Radiotherapy and Chemotherapy Qian’an People’s HospitalQian’an 064400Hebei ProvinceChina Department of Pathology China-Japan Friendship HospitalBeijing 100029China Department of Endocrinology Aksu First People's HospitalAksu Region 843000Xinjiang Uygur Autonomous RegionChina Department of Metabolic Diseases Qian’an Traditional Chinese Medical HospitalQian’an 064400Hebei ProvinceChina

BACKGROUND Juvenile hemochromatosis(JH)is an early-onset,rare autosomal recessive disorder of iron overload observed worldwide that leads to damage in multiple *** mutations in the hemojuvelin(HJV)gene are the major cause of *** SUMmaRY A 34-year-old male Chinese patient presented with liver fibrosis,diabetes,hypogonadotropic hypogonadism,hypophysis hypothyroidism,and skin *** test revealed a markedly elevated serum ferritin level of 4329μg/L and a transferrin saturation rate of 95.4%.Targeted exome sequencing and Sanger sequencing revealed that the proband had a novel mutation c.863G>A(p.R288Q)in the HJV gene which was transmitted from his father,and two known mutations,c.18G>C(p.Q6H)and c.962_963delGCinsAA(p.C321*)in cis,which were inherited from his *** p.R288W mutation was previously reported to be pathogenic for hemochromatosis,which strongly supported the pathogenicity of p.R288Q reported for the first time in this *** 72 wk of intensive phlebotomy therapy,the patient achieved a reduction in serum ferritin to 160.5μg/*** patient's clinical symptoms demonstrated a notable *** This study highlights the importance of screening for hemochromatosis in patients with diabetes and hypogonadotropic *** also suggests that long-term active phlebotomy could efficiently improve the prognosis in severe JH.

关键词： Juvenile hemochromatosis Liver cirrhosis Diabetes Iron overload Phlebotomy Case report

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论藏传佛教中国化进程中的中央王朝因素——以元明清三代为例

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中国藏学 2024年第1期 22-31,209,210页

作者：班玛更珠中国藏学研究中心历史研究所北京100101

佛教自公元7世纪传入西藏就开始了本土化历程,从吐蕃时期王室主导推动到分裂割据时期自主以教派形式走向民间,佛教在西藏最初阶段的曲折发展过程中也探索出了实现中国化的主要方向、基本路径、转化标准和推动方式。元代以来,西藏地方正... 详细信息

佛教自公元7世纪传入西藏就开始了本土化历程,从吐蕃时期王室主导推动到分裂割据时期自主以教派形式走向民间,佛教在西藏最初阶段的曲折发展过程中也探索出了实现中国化的主要方向、基本路径、转化标准和推动方式。元代以来,西藏地方正式纳入中央王朝的行政管辖,这一历史新阶段的开启也宣告藏传佛教中国化进程中出现了中央王朝这个最强有力的推动者和引导者。元明清三代,中央王朝均制定实施了相应的藏传佛教管理制度,在三代中央王朝的引导和推动下,这一时期藏传佛教不但积极、主动地尊奉中央王朝、亲近内地文化,而且在教派传承、教义教理、管理制度、文化交流、学经教育、寺庙经济等方面都有了不断适应本土特性的创新和发展。与此同时,在历代中央王朝的庇荫下,藏传佛教加快对外传播,不再局限于涉藏地区、藏语、藏文和藏族,从而成为根植中华大地、多民族共享的文化,实现了藏传佛教更进一步的本土化。

关键词：宗教中国化藏传佛教元明清政教合一活佛转世

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An effective strategy for dendrite free Li metal anodes:Nickel foam decorated with high lattice-matching CoN and CoF_(2) nanosheets for dense deposition

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Nano Research 2024年第5期17卷 4069-4078页

作者： Wenlong Liu Jianzong man Xiaodong Sun Ning Zhang Yehong Du kun Liu Zhongsheng Wen Song Li Juncai Sun Institute of materials and Technology Dalian Maritime UniversityDalian 116026China Shandong Provinvial Key Laboratory of Chemical Energy Storage and Novel Cell Technology and School of Chemistry and Chemical enginneringLiaocheng UniversityLiaocheng 252000China Department of Public Security management Liaoning Police CollegeDalian 116036China

The notorious dendrite and infinite volume change seriously restrict the advancement of lithium metal anodes(Lmas),during the long-term process of stripping/***,the nanosheets of metal fluoride(CoF_(2))and metal nitride(CoN)with magnificent lithiophilicity on the nickel(Ni)foam are designed as the“regulator”to uniform the Li plating and build stronger solid electrolyte interface(SEI)layer for dendrite free *** Ni foam offers abundant space to receive deposited Li *** CoN nanosheets can guarantee the fast transfer of electrons,which provides a stable interface of Li^(+)***,the nanosheet structure with lithiophilicity would accelerate the move of Li+and decrease the nucleation barrier,due to the high lattice-matching of Li and ***,the CoF_(2) could increase the content of F(LiF)in the SEI layer,which enhances the strength and avoids the destruction of SEI *** the cooperation of CoN and CoF_(2),the composited anode(Li/NF@CNCF)exhibits ultra-long cycle performance(more than 1200 h)and fantastic structure stability at 1 ma·cm^(-2) with 1 mah·cm^(-2).Based on the LiFePO_(4) and Li/NF@CNCF,the full cells deliver excellent specifical capacity and steady coulombic *** strategy contributes an effective approach to alleviate the issues of lithium metal anodes in the field of Lmas.

关键词： CoN and CoF_(2) lattice-matching nanosheet lithiophilicity lithium metal anodes

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