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World Journal of Gastroenterology 2015年第4期21卷 1315-1323页

作者： kui sun choi Sae Byeol choi Pyoungjae Park Wan Bae Kim Sang Yong choi Department of Surgery Korea University College of MedicineSeoul 152-703South Korea

AIM: To perform a systematic review of incidental or unsuspected gallbladder(GB) cancer diagnosed during or after cholecystectomy. METHODS: Data in Pub Med, EMBASE, and CochraneLibrary were reviewed and 26 publications were included in the meta-analysis. The inclusion criterion for incidental GB cancer was GB cancer diagnosed during or after cholecystectomy that was not suspected at a preoperative stage. Pooled proportions of the incidence, distribution of T stage, and revisional surgery of incidental GB cancer were ***: The final pooled population comprised 2145 patients with incidental GB cancers. Incidental GB cancers were found in 0.7% of cholecystectomies p e r f o r m e d f o r b e n i g n g a l l b l a d d e r d i s e a s e s o n preoperative diagnosis(95%CI: 0.004-0.012). Nearly 50% of the incidental GB cancers were stage T2 with a pooled proportion of 47.0%(95%CI: 0.421-0.519). T1 and T3 GB cancers were found at a similar frequency, with pooled proportions of 23.0%(95%CI: 0.178-0.291) and 25.1%(95%CI: 0.195-0.317), respectively. The pooled proportion that completed revisional surgery for curative intent was 40.9%(95%CI: 0.329-0.494). The proportion of patients with unresectable disease upon revisional surgery was 23.0%(95%CI: 0.177-0.294). CONCLUSION: A large proportion of incidental GB cancers were T2 and T3 lesions. Revisional surgery for radical cholecystectomy is warranted in T2 and more advanced cancers.

关键词： Gallbladder cancer Laparoscopic surgery Cholecyste

An ultra-sensitive biosensor for circulating microRNA detection with Fe single-atom enhanced cathodic luminol-O_(2) electrochemiluminescence

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Nano Research 2024年第9期17卷 7926-7934页

作者： Yudie sun Yunxiang Han Mingyue Wang Mingfu Ye Konglin Wu kui Zhang School of Chemistry and Chemical Engineering Anhui University of TechnologyMa'anshan 243032China Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science MOEQingdao University of Science and TechnologyQingdao 266042China Engineering Research Center of Biofilm Water Purification and Utilization Technology of Ministry of Education Anhui University of TechnologyMa'anshan 243032China

Circulating microRNAs(miRNAs)play a pivotal role in the occurrence and development of acute myocardial infarction(AMI),and precise detection of them holds significant clinical *** development of luminol-based luminophores in the field of electrochemiluminescence(ECL)for miRNA detection has been significant,while their effectiveness is hindered by the instability of co-reactant hydrogen peroxide(H_(2)O_(2)).In this work,an iron single-atom catalyst(Fe-PNC)was employed for catalyzing the luminol-O_(2) ECL system to achieve ultra-sensitive detection of myocardial *** miRNA triggers a hybridization chain reaction(HCR),resulting in the generation of a DNA product featuring multiple sticky ends that facilitate the attachment of Fe-PNC probes to the electrode *** Fe-PNC catalyst exhibits high promise and efficiency for the oxygen reduction reaction(ORR)in electrochemical energy conversion *** resulting ECL biosensor allowed ultrasensitive detection of myocardial miRNA with a low detection limit of 0.42 fM and a wide linear range from 1 fM to 1.0 ***,it demonstrates exceptional performance when evaluated using serum samples collected from patients with *** work expands the application of single-atom catalysis in ECL sensing and introduces novel perspectives for utilizing ECL in disease diagnosis.

关键词： circulating miRNAs single-atom catalyst luminol-O_(2) electrochemiluminescence hybridization chain reaction

Survival prognostic analysis of laparoscopic D2 radical resection for locally advanced gastric cancer: A multicenter cohort study

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2451-2460页

作者： Xiu-Ming sun kui Liu Wen Wu Chao Meng Department of Pain Management Affiliated Hospital of Qingdao UniversityQingdao 266000Shandong ProvinceChina Department of Hepatobiliary Surgery Affiliated Hospital of Qingdao UniversityQingdao 266000Shandong ProvinceChina Department of Gastrointestinal Surgery The First Affiliated Hospital of Naval Medical UniversityShanghai 200433China

BACKGROUND With the development of minimally invasive surgical techniques,the use of laparoscopic D2 radical surgery for the treatment of locally advanced gastric cancer(GC)has gradually ***,the effect of this procedure on survival and prognosis remains *** study evaluated the survival and prognosis of patients receiving laparoscopic D2 radical resection for the treatment of locally advanced GC to provide more reliable clinical evidence,guide clinical decision-making,optimize treatment strategies,and improve the survival rate and quality of life of *** A retrospective cohort study was *** data from 652 patients with locally advanced GC in our hospitals from December 2013 to December 2023 were *** were 442 males and 210 *** mean age was 57±12 *** patients underwent a laparoscopic D2 radical operation for distal *** patients were followed up in the outpatient department and by telephone to determine their tumor recurrence,metastasis,and *** follow-up period ended in December *** distributed data are expressed as the mean±SD,and normally distributed data are expressed as M(Q1,Q3)or M(range).Statistical data are expressed as absolute numbers or percentages;theχ^(2) test was used for comparisons between groups,and the Mann-Whitney U nonparametric test was used for comparisons of rank *** life table method was used to calculate the survival rate,the Kaplan-Meier method was used to construct survival curves,the log rank test was used for survival analysis,and the Cox risk regression model was used for univariate and multifactor *** The median overall survival(OS)time for the 652 patients was 81 months,with a 10-year OS rate of 46.1%.Patients with TNM stages II and III had 10-year OS rates of 59.6%and 37.5%,respectively,which were significantly different(P<0.05).Univariate analysis indicated that factors such as age,maximum tumor diameter,tum

关键词： Gastric neoplasms Chinese Laparoscopic Gastrointestinal Surgery Study Group Laparoscopic surgery Locally advanced gastric cancer D2 lymph node dissection

Correlation between hydration properties and electrochemical performances on Ln cation size effect in layered perovskite for protonic ceramic fuel cells

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Journal of Energy Chemistry 2024年第1期88卷 1-9,I0001页

作者： Inhyeok Cho Jiwon Yun Boseok Seong Junseok Kim sun Hee choi Ho-Il Ji Sihyuk choi Department of Mechanical Engineering Kumoh National Institute of TechnologyGumi 39177GyeongbukRepublic of Korea Department of Aeronautics Mechanical and Electronic Convergence EngineeringKumoh National Institute of TechnologyGumi 39177GyeongbukRepublic of Korea Center for Energy Materials Research Korea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea Center for Hydrogen and Fuel Cell Research Clean Technology Research DivisionKorea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea Department of Energy and Environmental Engineering University of Science and TechnologySeoul 02792Republic of Korea Nanomaterials Science and Engineering Korea University of Science and Technology(UST)KIST CampusSeoul 02792Republic of Korea

PrBa_(0.5)Sr_(0.5)Co_(1.5)Fe_(0.5)O_(5+δ)(PrBSCF) has attracted much research interest as a potential triple ionic and electronic conductor(TIEC) electrode for protonic ceramic fuel cells(PCFCs). The chemical formula for Pr BSCF is AA'B_(2)O_(5+δ), with Pr(A-site) and Ba/Sr(A'-site) alternately stacked along the c-axis. Due to these structural features, the bulk oxygen ion diffusivity is significantly enhanced through the disorder-free channels in the PrO layer;thus, the A site cations(lanthanide ions) play a pivotal role in determining the overall electrochemical properties of layered perovskites. Consequently, previous research has predominantly focused on the electrical properties and oxygen bulk/surface kinetics of Ln cation effects,whereas the hydration properties for PCFC systems remain unidentified. Here, we thoroughly examined the proton uptake behavior and thermodynamic parameters for the hydration reaction to conclusively determine the changes in the electrochemical performances depending on LnBa_(0.5)Sr_(0.5)Co_(1.5)Fe_(0.5)O_(5+δ)(LnBSCF,Ln=Pr, Nd, and Gd) cathodes. At 500 ℃, the quantitative proton concentration of PrBSCF was 2.04 mol% and progressively decreased as the Ln cation size decreased. Similarly, the Gibbs free energy indicated that less energy was required for the formation of protonic defects in the order of Pr BSCF < Nd BSCF < Gd BSCF. To elucidate the close relationship between hydration properties and electrochemical performances in LnBSCF cathodes, PCFC single cell measurements and analysis of the distribution of relaxation time were further investigated.

关键词： Protonic ceramic fuel cell Cathode Triple ionic and electronic conductor Hydration property Proton uptake Gibbs free energy

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Controllable synthesis of one-dimensional silicon nanostructures based on the dual effects of electro-deoxidation and the Kirkendall effect

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Nano Research 2024年第9期17卷 7814-7823页

作者： Jianxin Tu Shuo Yu kui Hao Le sun Ruicheng Bai Fangzhou Zhang Aijun Li Hong Liu Institute of Materials School of Materials Science and EngineeringShanghai UniversityShanghai 200444China Department of Applied Physics The Hong Kong Polytechnic UniversityKowloon 999077Hong KongChina Shaoxing institute of technology Shanghai UniversityShanghai 200444China

In this study,we successfully synthesized silicon nanotubes(Si-NTs)and silicon nanowires(Si-NWs)in a controllable manner using a catalyst-and template-free method through the direct electrolysis of SiO_(2)in a molten CaCl_(2)-CaO system,while also proposing a novel formation mechanism for ***-NWs are formed through electro-deoxidation when the cell voltage is within the range of CaO decomposition voltage and SiO_(2)decomposition *** subsequently adjusting the voltage to a value between the decomposition potentials of CaCl_(2)and CaO,in-situ electro-deoxidation of CaO takes place on the surface of the synthesized Si-NWs,leading to the formation of a Ca *** formation of Ca-Si diffusion couple leads to the creation of vacancies within the Si-NWs,as the outward diffusion rate of Si exceeds the inward diffusion rate of *** differential diffusion rates between Si and Ca in a diffusion couple exhibit an analogy to the Kirkendall *** vacancies gradually accumulate and merge,forming large voids,which ultimately result in the formation of hollow *** a subsequent dealloying process,the removal of the embedded calcium leads to the formation of *** the application of a carbon coating,the Si-NTs@C composite showcases a high initial discharge capacity of 3211 mAh·g^(-1)at 1.5 A·g^(-1)and exhibits exceptional long-term cycling stability,maintaining a capacity of 977 mAh·g^(-1)after 2000 cycles at 3.0 A·g^(-1).

关键词： silicon nanotubes silicon nanowires lithium-ion battery Kirkendall effect

The nodule-specific transcriptional repressor Top Hub 4 regulates nodule structure and nitrogen fixation capacity in soybean

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Journal of Genetics and Genomics 2024年第1期51卷 96-99页

作者： kui Ge Qi Lv Shengcai Chen Zhenhao Guo Yaqi Peng Yimian Chen Shiyong sun Xuelu Wang College of Life Science and Technology Huazhong Agricultural UniversityWuhanHubei 430070China State Key Laboratory of Crop Stress Adaptation and Improvement School of Life SciencesHenan UniversityZhengzhouHenan 450046China The Academy for Advanced Interdisciplinary Studies Henan UniversityZhengzhouHenan 450046China Sanya Institute of Henan University SanyaHainan 572025China

Most leguminous plants establish symbiotic relationships with rhizobia to form root organs called nodules(Ferguson et al.,2010).Nodules are specialized organs containing bacterial symbionts,which can provide enormous amounts of fixed nitrogen to their plant hosts(Peoples et al.,2009).Soybean(Glycine max),an economically important grain and oil crop,forms symbiotic nitrogen-fixing nodules,which reduces the demand for chemical nitrogen fertilizers and promotes yield(Saito et al.,2014).Nodule development is spatiotemporally regulated by the action of a number of transcription factors(TFs).

关键词： specialized organs soybean

Sand control mechanism of radial well filled with phase change material in hydrate reservoir

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Petroleum Science 2024年第4期21卷 2571-2582页

作者： Xiao-Qiang Liu Zhong-Xi Han Zhi-Lin Luo Hai-Long Lu Ying sun Qing You Tian-kui Guo Zhan-Qing Qu School of Energy Resources China University of Geosciences (Beijing) Beijing Key Laboratory of Unconventional Natural Gas Geological Evaluation and Development Engineering China University of Geosciences (Beijing) China Research Institute of Petroleum Exploration and Development Engineering Technology Research Institute of Southwest Oil & Gas Field Company PetroChina Beijing International Center for Gas Hydrate School of Earth and Space Sciences Peking University School of Advanced Material Peking University Shenzhen Graduate School School of Petroleum Engineering China University of Petroleum (East China)

Radial well filled with phase change material has been proposed as a novel sand control method for hydrate exploitation. In order to reveal the sand control mechanism, CFD-DEM coupling method is applied to simulate the migration, settlement, and blockage processes of sand particles in the radial *** obtained results indicate that three scenarios have been recognized for sand particles passing through sand control medium, based on the diameter ratio of sand control medium to sand particle（Dd）:fully passing（Dd= 8.75-22.5）, partially passing and partially blocked（Dd= 3.18-5.63）, and completely blocked（Dd= 2.18-3.21）. After being captured by the sand control medium, sand particles can block pores, which increases fluid flow resistance and causes a certain pressure difference in the radial *** pressure in the radial well should be lower than the hydrate phase equilibrium pressure during sand control design, for the purpose of promoting hydrate decomposition, and sand capture. The length of the radial well should be optimized based on the reservoir pore pressure, production pressure difference,bottom hole pressure, and the pressure gradient in the radial well. It should be noticed that the sand control medium leads to a decrease in permeability after sand particles captured. Even the permeability is reduced to several hundred millidarcy, it is still sufficient to ensure the effective flow of gas and water after hydrate decomposition. Increasing fluid velocity reduces the blocking capacity of the sand control medium, mainly because of deterioration in bridging between sand particles.

关键词： Hydrate reservoir Sand control Radial well CFD-DEM

Virtual vibration test rig for fatigue analysis of dozer push arms

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International Journal of Mechanical System Dynamics 2024年第3期4卷 278-291页

作者： Lei Hou Weibin Li Wenyan Gu Zizheng sun Xiangqian Zhu Jin-Hwan choi Key Laboratory of High-Efficiency and Clean Mechanical Manufacture of MOE National Demonstration Center for Experimental Mechanical EngineeringSchool of Mechanical EngineeringShandong UniversityJinanChina Rizhao Research Institute of Shandong University RizhaoChina School of Aerospace Engineering Xiamen UniversityXiamenChina School of Qilu Transportation Shandong UniversityJinanChina Department of Mechanical Engineering Kyunghee UniversitySeoulSouth Korea

To obtain accurate fatigue life results for construction machinery components,acquiring load spectra is crucial,as their authenticity and validity directly determine the precision of the *** working conditions,component attitudes change continuously,but they remain static on the vibration test rig(VTR),so the acquired target signals should match with the actual component attitudes in the driving signal *** paper proposes an efficient and economical simulation-based virtual VTR for fatigue analysis of ***,the relationship between the push arm rotation angle and the cylinder stroke is established,since the cylinder strokes can be measured easily in data acquisition ***,load decomposition is used to determine the attitude relationship between virtual VTR conditions and actual conditions,and target signals are calculated based on this attitude relationship and measured *** to the system's frequency response function,the driving signals are iterated until the system's response signals converge with the target ***,the iteratively obtained load spectra are utilized for fatigue life *** results show that the virtual VTR can effectively and accurately obtain the results of fatigue analysis and has engineering application significance.

关键词： virtual vibration test rig driving signal generation component attitudes fatigue analysis dozer push arm

Weak Merging Scenario of CLASH Cluster A209

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Research in Astronomy and Astrophysics 2024年第4期24卷 174-182页

作者： Wen-Cheng Feng Heng Yu Hai-Hui Zhao Xiao-Lan Hou Shu-Mei Jia Cheng-kui Li Yu-Lin Cheng Paolo Tozzi Ming sun Yong Chen Department of Physics and Institute of Theoretical Physics Nanjing Normal UniversityNanjing 210023China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Department of Astronomy Beijing Normal UniversityBeijing 100875China Department of Astronomy Yunnan UniversityKunming 650091China INAF—Osservatorio Astrofisico di Arcetri Largo E.Fermi50122 FirenzeItaly Department of Astronomy University of VirginiaP.O.Box 400325CharlottesvilleVA 22904-4325USA

We study the structural and dynamical properties of A209 based on Chandra and XMM-Newton *** obtain detailed temperature,pressure,and entropy maps with the contour binning method,and find a hot region in the NW *** X-ray brightness residual map and corresponding temperature profiles reveal a possible shock front in the NW direction and a cold front feature in the SE *** with the galaxy luminosity density map we propose a weak merger scenario.A young sub-cluster passing from the SE to NW direction could explain the optical subpeak,the intracluster medium temperature map,the X-ray surface brightness excess,and the X-ray peak offset together.

关键词： X rays:galaxies:clusters galaxies:clusters:intracluster medium galaxies:clusters:Abell 209

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基于改进T-B法的宽带高斯过程疲劳损伤分析

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船舶力学 2024年第2期28卷 261-272页

作者：袁奎霖孙卓成大连理工大学工业装备结构分析国家重点实验室船舶工程学院辽宁大连116024

针对宽带高斯随机应力过程造成的疲劳损伤问题,本文提出一种基于改进Tovo-Benasciutti(T-B)法的疲劳损伤频域分析方法。通过不同参数形式的功率谱进行时域的疲劳损伤分析,针对T-B法中的关键参数bTB提出一个新的非线性函数模型。与原T-B... 详细信息

针对宽带高斯随机应力过程造成的疲劳损伤问题,本文提出一种基于改进Tovo-Benasciutti(T-B)法的疲劳损伤频域分析方法。通过不同参数形式的功率谱进行时域的疲劳损伤分析,针对T-B法中的关键参数bTB提出一个新的非线性函数模型。与原T-B法相比,新提出的函数模型bMTB可以考虑S-N曲线斜率参数m的影响,并以此为基础提出基于改进T-B法的疲劳损伤分析方法。以时域的雨流计数法结果作为基准,分别采用参数化功率谱和真实响应谱进行数值试验,并与现有的多种宽带高斯疲劳损伤分析方法进行对比,验证本文所提出的改进T-B法的准确性和适用性。

关键词：宽带高斯随机过程疲劳损伤改进T-B谱方法数值模拟

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