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Experimental study on the feasibility and safety of radiofrequency ablation for secondary splenomagely and hypersplenism

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World Journal of Gastroenterology 2003年第4期9卷 813-817页

作者： Quan-DaLiu kuan-shengma Zhen-PingHe JunDing Xue-QuanHuang Jia-HongDong InstituteofHepatobiliarySurgery SouthwestHepatohiliarySurgeryHospitalSouthwestHospitalThirdMilitaryMedicalUniversityChongqing400038China DepartmentofRadiology SouthwestHospitalThirdMilitaryMedicalUniversityChongqing400038China

AIM: To assess the feasibility and safety of radiofrequency ablation (RFA) in treatment of secondary splenomagely and ***: Sixteen healthy mongrel dogs were randomly divided into two groups, group Ⅰ (n=4) and group Ⅱ (n=12).Congestive splenomegaly was induced by ligation of splenic vein and its collateral branches in both groups. At the end of 3rd week postoperation, RFA in spleen was performed in group Ⅱ via laparotomy, complications of RFA were observed,CT scan was performed and the spleens were *** radiofrequency (RF) thermal lesions and histopathology of spleen were examined ***: No complication or death was observed in both groups; CT revealed that the splenomegaly lasted over 2months after ligation of splenic vein; the segmental RF lesions included hyperintense zone of coagulative necrosis and more extensive peripheral hypointense infarcted zone, the latter was called 'bystander effect'. The infarcted zone would be absorbed and subsequently disappeared in 4-6 weeks after RFA accompanied with shrinkage of the remnant *** fundamental histopathological changes of splenic lesions caused by RF thermal energy included local coagulative necrosis, peripheral thrombotic infarction zone, subsequent tissue absorption and fibrosis in the zone of thrombotic infarction, the occlusion of vessels in remnant viable spleen,deposition of extensive fibrous protein, and disappearance of congestive splenic sinusoid - 'splenic carnification'. Those pathologic changes were underline of shrinkage of ***: It is feasible and safe to perform RFA in spleen to treat experimental splenomegaly and hypersplenism. The RFA could be safely performed clinically via laparotomy or laparoscopic procedure while spleen was strictly separated from surrounding organs.

关键词：脾机能亢进继发性脾肿大射频消融术安全性动物模型

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Role of preoperative selective portal vein embolization in two-step curative hepatectomy for hepatocellular carcinoma

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World Journal of Gastroenterology 2003年第8期9卷 1702-1706页

作者： WuJi Jie-ShouLi Ung-TangLi Wu-HongLiu kuan-shengma Xiang-TianWang Zhen-PingHe Jia-HongDong ResearchInstituteofGeneralSurge NanjingGeneralHospitaloiNanjingPLACommandAreaNanjing210002.JiangsuProvince.China DepartmentofGeneralSurgery KunmingGeneralHospitalofChengduPLACommandAreaKunming650032YunnanProvinceChina HepatobiliarySurgeryCenter SouthwestHospitalThirdMilitaryMedicalUniversityChongqing400038China

AIM: To determine the feasibility and role of ultrasoundguided preoperative selective portal vein embolization (POSPVE) in the two-step hepatectomy of patients with advanced primary hepatocellular carcinoma (HCC).METHODS: Fifty patients with advanced HCC who were not suitable for curative hepatectomy were treated by ultrasound-guided percutaneous transhepatic POSPVE with fine needles. The successful rate, side effects and complications of POSPVE, changes of hepatic lobe volume and two-step curative hepatectomy rate after POSPVE were ***: POSPVE was successfully performed in 47(94.0 %) patients. In patients whose right portal vein branches were embolized, their right hepatic volume decreased and left hepatic volume increased gradually. The ratio of right hepatic volume to total hepatic volume decreased from 62.4 % before POSPVE to 60.5 %, 57.2 %and 52.8 % after 1, 2 and 3 weeks respectively. The side effects included different degree of pain in liver area (38cases), slight fever (27 cases), nausea and vomiting (9cases). The level of aspartate alanine transaminase (AST),alanine transaminase (ALT) and total bilirubin (TBIL)increased after POSPVE, but returned to preoperative level in 1 week. After 2-4 weeks, two-step curative hepatectomy for HCC was successfully performed on 23 (52.3 %) *** were no such severe complications as ectopic embolization, local hemorrhage and bile ***: Ultrasound-guided percutaneous transhepatic POSPVE with fine needles is feasible and safe. It can extend the indications of curative hepatectomy of HCC, and increase the safety of hepatectomy.

关键词：肝细胞癌肝切除术术前选择性血管栓塞化疗

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Pancreatic stent improves the success rate of needle-knife papillotomy in patients with difficult biliary cannulation

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World Journal of Gastroenterology 2025年第1期31卷 58-67页

作者： Mu-Hsien Lee Cheng-Hui Lin Chi-Huan Wu Yung-kuan Tsou Kai-Feng Sung Sheng-Fu Wang Nai-Jen Liu Department of Gastroenterology and Hepatology Chang Gung Memorial Hospital and Chang Gung University College of MedicineTaoyuan 33305Taiwan School of Medicine Chang Gung UniversityTaoyuan 33305Taiwan

BACKGROUND Needle-knife precut papillotomy(NKP)is typically performed ***,it remains unclear whether pancreatic stent(PS)placement can improve the outcomes of *** To explore whether PS placement improves the success rate of NKP in patients with difficult biliary *** This single-center retrospective study included 190 patients who underwent NKP between January 2017 and December 2021 after failed conventional biliary *** cases with incidental pancreatic duct cannulation during conventional biliary cannulation,the decision for pre-NKP PS placement was made at the endoscopist's *** primary outcome was the difference in the NKP success rate between patients with and without PS placement;the secondary outcome was the adverse event *** Among the 190 participants,82 received pre-NKP PS(PS-NKP group)whereas 108 did not[freehand or freehand NKP(FH-NKP)group].Post-NKP selective biliary cannulation was successful in 167(87.9%)patients,and the PS-NKP had a significantly higher success rate than the FH-NKP group(93.9%vs 83.3%,P=0.027).The overall adverse event rates were 7.3%and 11.1%in the PS-NKP and FH-NKP groups,respectively(P=0.493).A periampullary diverticulum(PAD)and significant intraoperative bleeding during NKP were independently associated with NKP failure;however,a pre-NKP PS was the only predictor of NKP *** the 44 participants with PADs,the PS-NKP group had a non-significantly higher NKP success rate than the FH-NKP group(87.5%and 65%,respectively;P=0.076).CONCLUSION PS significantly improved the success rate of NKP in patients with difficult biliary cannulation.

关键词： Difficult biliary cannulation Endoscopic retrograde cholangiopancreatography Needle-knife papillotomy Pancreatic stent Selective biliary cannulation

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Enhancing postoperative pain control by surgically-initiated rectus sheath block in abdominal aortic aneurysm open repair: A case report

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World Journal of Clinical Cases 2025年第6期13卷 41-47页

作者： kuan-Hua Chen Ming-Yuan Kang Yi-Ting Chang Sheng-Yang Huang Yung-Szu Wu Center for Cardiovascular Disease Taichung Veterans General HospitalTaichung 407219TaiwanChina Department of Anesthesiology Taichung Veterans General HospitalTaichung 407219TaiwanChina Division of Pediatric Surgery Department of SurgeryTaichung Veterans General HospitalTaichung 407219TaiwanChina School of Medicine National Yang Ming Chiao Tung UniversityTaipei 112304TaiwanChina Department of Post-Baccalaureate Medicine National Chung Hsing UniversityTaichung 402202TaiwanChina

BACKGROUND Abdominal aortic aneurysm(AAA)repair often involves significant postoperative pain,traditionally managed with systemic opioids,which can cause undesirable side *** case report explores the novel use of a surgically-initiated rectus sheath block with a catheter-over-needle assembly for pain management in AAA *** SUMMARY A 67-year-old female with hypertension and previous aortic dissection underwent elective open repair of an infrarenal AAA,which had grown from 3.4 cm to 4.3 cm over 14 months.A rectus sheath block was initiated surgically for postoperative pain *** patient reported low pain scores and did not require systemic intravenous opioids,enabling early ambulation and discharge on postoperative day seven without *** preventing complications of systemic opi-oids,the method indicating a promising direction for postoperative pain management in major vascular *** Surgically-initiated rectus sheath block as a valuable tool for managing postoperative pain in AAA repair.

关键词： Abdominal aortic aneurysm Postoperative pain management Rectus sheath block Surgical anesthesia Opioid-sparing techniques Case report

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Success of intravenous immunoglobulin and steroids in managing severe COVID-19 following lung transplantation:A case report

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World Journal of Transplantation 2025年第1期15卷 178-184页

作者： Yen-Shou Kuo kuan-Hsun Lin Ying-Yi Chen Yuan-Ming Tsai Ti-Hui Wu Hsu-Kai Huang Tsai-Wang Huang Division of Thoracic Surgery Department of SurgeryTri-Service General HospitalNational Defense Medical CenterTaipei 114202Taiwan

BACKGROUND Coronavirus disease 2019(COVID-19)pneumonia with severe septic shock and acute respiratory distress syndrome(ARDS)are critical illnesses for patients following *** immunoglobulin(IVIG)plays a role in both immune support and inflammation control,especially in immunocompromised *** case report describes the first successful experience using IVIG and pulse steroids to manage this critical condition following lung *** SUMMARY A 65-year-old male patient reported a history of chronic obstructive pulmonary disease and poor lung function and received bilateral sequential lung ***,he developed COVID-19 pneumonia,severe septic shock,and *** recovered from this critical condition after empirical antibiotics administration and veno-venous extracorporeal membrane oxygenation,in addition to IVIG and pulse *** IVIG is a valuable adjunct in managing severe sepsis in lung transplant recipients after COVID-19 *** aim,for the first time,to report the success of such a management approach for COVID-19 ARDS and sepsis in the post-lung transplant *** further investigations,this is a starting point for wider analysis of such an approach in this setting and consequently helps guide clinical practice for such a challenging patient population moving forward.

关键词： COVID-19 Septic shock Intravenous immunoglobulin Lung transplantation Post-transplant complications Case report

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Enhancement of Metastatic and Invasive Capacity of Gastric Cancer Cells by Transforming Growth Factor-β1

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Acta Biochimica et Biophysica Sinica 2006年第3期38卷 179-186页

作者： kuan-Song WANG Central South University Changsha 410013 China Department of Pathology Basic School of Medicine

Transforming growth factor-β (TGF-β),a multifunctional cytokine,exerts contradictory rolesin different kinds of cells.A number of studies have revealed its involvement in the progression of many typesof *** investigate the effect of TGF-β on gastric carcinoma,SGC7901,BGC823 and MKN28 (aTGF-β-resistant cell line) adenocarcinoma clones were *** pretreatment in serum-free medium withor without 10 ng/ml TGF-β1,their experimental metastatic potential,chemotaxis,and invasive and adhesiveability were ***,zymography for gelatinase was *** colonies were alsomeasured 4 weeks after inoculation of SGC7901,BGC823 and MKN28 in Balb/c nude mice,and an increasein the number of surface liver metastases was seen in SGC7901 (from 11.0±3.0 to 53.3±3.3) and BGC823(from 9.3±2.5 to 60.0±2.8) groups,whereas there was no difference between MKN28 groups (from 35.2±3.8 to 38.5±2.7).In vitro experiments showed that TGF-β1 increased the adhesion capacity of SGC7901and BGC823 cells to immobilized reconstituted basement membrane/fibronectin matrices and promoted theirpenetration through reconstituted basement membrane *** demonstrated that enhancedinvasive potential was partly due to the increased type Ⅳ collagenolytic (gelatinolytic) activity,but there wasno difference in type Ⅳ collagenolytic activity and other biological behaviors between MKN28 *** suggested that TGF-β1 might modulate the metastatic potential of gastric cancer cells by promotingtheir ability to break down and penetrate basement membrane barriers and their adhesive and motile *** speculated that TGF-β1 might act as a progression-enhancing factor in gastric *** blockageof TGF-β or TGF-β signaling might prevent gastric cancer cells from invading and metastasizing.

关键词： gastric cancer transforming growth factor-β invasion metastasis

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Wavelet Energy Feature Extraction and Matching for Palmprint Recognition

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Journal of Computer Science & Technology 2005年第3期20卷 411-418页

作者： Xiang-QianWu kuan-QuanWang DavidZhang SchoolofComputerScienceandTechnology HarbinInstituteofTechnologyHarbin150001P.R.China BiometricsResearchCentre DepartmentofComputingHongKongPolytechnicUniversity

According to the fact that the basic features of a palmprint, includingprincipal lines, wrinkles and ridges, have different resolutions, in this paper we analyzepalmprints using a multi-resolution method and define a novel palmprint feature, which calledwavelet energy feature (WEF), based on the wavelet transform. WEF can reflect the wavelet energydistribution of the principal lines, wrinkles and ridges in different directions at differentresolutions (scales), thus it can efficiently characterize palmprints. This paper also analyses thediscriminabilities of each level WEF and, according to these discriminabilities, chooses a suitableweight for each level to compute the weighted city block distance for recognition. The experimentalresults show that the order of the discriminabilities of each level WEF, from strong to weak, is the4th, 3rd, 5th, 2nd and 1st level. It also shows that WEF is robust to some extent in rotation andtranslation of the images. Accuracies of 99.24% and 99.45% have been obtained in palmprintverification and palmprint identification, respectively. These results demonstrate the power of theproposed approach.

关键词： biometrics palmprint recognition wavelet energy feature weighted cityblock distance

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Self-Organized Criticality in Small-World Networks Based on the Social Balance Dynamics

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Chinese Physics Letters 2011年第11期28卷 275-277页

作者： MENG Qing-kuan School of Science Shandong University of TechnologyZibo 255049

A node model is proposed to study the self-organized criticality in the small-world networks which represent the social *** on the node model and the social balance dynamics,the social networks are mapped to the thermodynamic systems and the phenomena are studied with physical *** is found that the avalanche in the small-world networks at the critical state satisfies the power-law distribution spatially and temporally.

关键词： Small networks avalanche

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Effect of Zn deficiency and excessive bicarbonate on the allocation and exudation of organic acids in two Moraceae plants

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Acta Geochimica 2018年第1期37卷 125-133页

作者： kuan Zhao Yanyou Wu School of Resources and Environment Anqing Normal University Anqing 246011 People's Republic of China State Key Laboratory of Environmental Geochemistry Institute of Geochemistry Chinese Academy of SciencesGuiyang 550002 People's Republic of China Key Laboratory of Modem Agricultural Equipment and Technology Chinese Ministry of Education Jiangsu University Zhenjiang 212013 People's Republic of China

The effect of zinc(Zn) deficiency and excessive bicarbonate on the allocation and exudation of organic acids in plant organs(root, stem, and leaf) and root exudates of two Moraceae plants(Broussonetia papyrifera and Morus alba) were investigated. Two Moraceae plants were hydroponically grown and cultured in nutrient solution in four different treatments with 0.02 mM Zn or no Zn,combined with no or 10 mM bicarbonate. The variations of organic acids in different plant organs were similar to those of root exudates in the four treatments except B. papyrifera, which was in a treatment that was a combination of 0.02 mM Zn and no bicarbonate. The response characteristics in the production, translocation, and allocation of organic acids in the plant organs and root exudates varied with species and treatments. Organic acids in plant organs and root exudates increased under Zn-deficient conditions,excessive bicarbonate, or both. An increase of organic acids in the leaves resulted in an increase of root-exuded organic acids. B. papyrifera translocated more oxalate and citrate from the roots to the rhizosphere than M. alba under the dual influence of 10 mM bicarbonate and Zn deficiency. Organic acids of leaves may be derived from dark respiration and photorespiration. By comparison, organic acids in stems, roots, and root exudates may be derived from dark respiration and organic acid translocation from the leaves. These results provide evidence for the selective adaptation of plants to environments with low Zn levels or high bicarbonate levels such as a karst ecosystem.

关键词： Adaptation Excessive bicarbonate Organic acids Organs Root exudates Zn deficiency

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Standard siren cosmology with the LISA-Taiji network

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Science China(Physics,Mechanics & Astronomy) 2022年第1期65卷 120-121页

作者： Zong-kuan Guo CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China

Gravitational waves(GWs)are a marvelous prediction of general *** GW waveform from a compact binary coalescence is theoretically predictable,and different binary systems emit GWs in different frequency *** frequencies of GWs emitted by stellar-mass binaries fall within the detection band of ground-based detectors(10-10^(4)Hz).GWs at lower frequencies(10^(-4)-1 Hz)emitted by massive black hole binaries(MBHBs)have wavelengths larger than the earth *** a GW detector large enough to efficiently detect them requires going to space.

关键词： massive stellar prediction

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