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A Cost-Efficient Approach to Storing Users'Data for Online Social Networks

Journal of Computer Science & Technology 2019年第1期34卷 234-252页

作者： Jing-Ya Zhou Jian-Xi Fan cheng-kuan Lin Bao-Lei cheng School of Computer Science and Technology Soochow UniversitySuzhou 215006China Provzncial Key Laboratory for Computer Information Processing Technology Soochow UniversitySuzhou 215006China Collaborative Innovation Center of Novel Software Technology and Industrialization Nanjing University Nanjing 210023China

As users increasingly befriend others and interact online via their social media accounts,online social networks (OSNs)are expanding *** with the big data generated by users,it is imperative that data storage be distributed,scalable,and *** one of the most significant challenges about this topic is determining how to minimize the cost without deteriorating system *** many storage systems use the distributed key value store,it cannot be directly applied to OSN storage *** because users'data are highly correlated,hash storage leads to frequent inter-server communications,and the high inter-server traffic costs decrease the OSN storage system's scalability. Previous studies proposed conducting network partitioning and data replication based on social ***,data replication increases storage costs and impacts traffic ***,we consider how to minimize costs from the perspective of data storage,by combining partitioning and *** cost-efficient data storage approach supports scalable OSN storage *** proposed approach co-locates frequently interactive users together by conducting partitioning and replication simultaneously while meeting load-balancing *** experiments are undertaken on two real- world traces,and the results show that our approach achieves lower cost compared with state-of-the-art *** we conclude that our approach enables economic and scalable OSN data storage.

关键词： online social network inter-server traffic cost storage cost network partitioning data replication

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Fault-Tolerant Hamiltonicity and Hamiltonian Connectivity of BCube with Various Faulty Elements

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Journal of Computer Science & Technology 2020年第5期35卷 1064-1083页

作者： Gui-Juan Wang cheng-kuan Lin Jian-Xi Fan Jing-Ya Zhou Bao-Lei cheng School of Computer Science and Technology Soochow UniversitySuzhou 215006China School of Computer Science and Technology Qilu University of Technology(Shandong Academy of Sciences)Jinan 250353China College of Mathematics and Computer Science Fuzhou UniversityFuzhou 350108China

BCube is one kind of important data center *** and Hamiltonian connectivity have significant applications in communication *** far,there have been many results concerning fault-tolerant Hamiltonicity and fault-tolerant Hamiltonian connectivity in some data center ***,these results only consider faulty edges and faulty *** this paper,we study the fault-tolerant Hamiltonicity and the fault-tolerant Hamiltonian connectivity of BCube(n,k)under considering faulty servers,faulty links/edges,and faulty *** any integers n≥2 and k≥0,let BCn,k be the logic structure of BCube(n,k)and F be the union of faulty elements of BCn,k,Let fv/fe,and fs be the number of faulty servers,faulty edges,and faulty switches of BCiLbe(n,k),*** show that BCnik-F is fault-tolerant Hamiltonian if fv+fe+(n-1)/s≤(n-1)(k+1)-2 and BCn,k-F is fault-tolerant Hamiltonian-connected ifv,+fe+(n-1)fs≤(n-1)(k+1)-*** the best of our knowledge,this paper is the first work which takes faulty switches into account to study the fault-tolerant Hamiltonicity and the fault-tolerant Hamiltonian connectivity in data center networks.

关键词： data center network BCube fault-tolerance Hamiltonicity Hamiltonian connectivity

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Optimal Path Embedding in the Exchanged Crossed Cube

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Journal of Computer Science & Technology 2017年第3期32卷 618-629页

作者： Dong-Fang Zhou Jian-Xi Fan cheng-kuan Lin Bao-Lei cheng Jing-Ya Zhou Zhao Liu School of Computer Science and Technology Soochow University Suzhou 215006 China Collaborative Innovation Center of Novel Software Technology and Industrialization Nanjing University Nanjing 210000 China

The （s＋t＋1）-dimensional exchanged crossed cube, denoted as ECQ（s, t）, combines the strong points of the exchanged hypercube and the crossed cube. It has been proven that ECQ（s, t） has more attractive properties than other variations of the fundamental hypercube in terms of fewer edges, lower cost factor and smaller diameter. In this paper, we study the embedding of paths of distinct lengths between any two different vertices in ECQ（s, t）. We prove the result in ECQ（s, t）： if s≥3, t≥3, for any two different vertices, all paths whose lengths are between max{9,「s＋1/2」＋「t＋1/2＋4}and 2s＋t＋1？1 can be embedded between the two vertices with dilation 1. Note that the diameter of ECQ（s, t） is「s＋1/2 」＋「t＋1/2 」＋2. The obtained result is optimal in the sense that the dilations of path embeddings are all 1. The result reveals the fact that ECQ（s, t） preserves the path embedding capability to a large extent, while it only has about one half edges of CQn.

关键词： interconnection network exchanged crossed cube path embedding parallel computing system

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BCDC： A High-Performance, Server-Centric Data Center Network

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Journal of Computer Science & Technology 2018年第2期33卷 400-416页

作者： Xi Wang Jian-Xi Fan cheng-kuan Lin Jing-Ya Zhou Zhao Liu School of Computer Science and Technology Soochow University Suzhou 215006 China School of Software and Services Outsourcing Suzhou Institute of Industrial Technology Suzhou 215004 China

The capability of the data center network largely decides the performance of cloud computing. However, the number of servers in the data center network becomes increasingly huge, because of the continuous growth of the application requirements. The performance improvement of cloud computing faces great challenges of how to connect a large number of servers in building a data center network with promising performance. Traditional tree-based data center networks have issues of bandwidth bottleneck, failure of single switch, etc. Recently proposed data center networks such as DCell, FiConn, and BCube, have larger bandwidth and better fault-tolerance with respect to traditional tree-based data center networks. Nonetheless, for DCell and FiConn, the fault-tolerant length of path between servers increases in case of failure of switches; BCube requires higher performance in switches when its scale is enlarged. Based on the above considerations, we propose a new server-centric data center network, called BCDC, based on crossed cube with excellent performance. Then, we study the connectivity of BCDC networks. Furthermore, we propose communication algorithms and fault-tolerant routing algorithm of BCDC networks. Moreover, we analyze the performance and time complexities of the proposed algorithms in BCDC networks. Our research will provide the basis for design and implementation of a new family of data center networks.

关键词： data center network interconnection network crossed cube server-centric fault-tolerant

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Optimally Embedding 3-Ary n-Cubes into Grids

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Journal of Computer Science & Technology 2019年第2期34卷 372-387页

作者： Wei-Bei Fan Jian-Xi Fan cheng-kuan Lin Yan Wang Yue-Juan Han Ru-Chuan Wang School of Computer Science and Technology Soochow University Suzhou 215006 China Jiangsu High Technology Research Key Laboratory for Wireless Sensor Networks Nanjing 210003 China College of Mathematics and Computer Science Fuzhou University Fuzhou 350108 China

The 3-ary n-cube,denoted as Qn3,is an important interconnection network topology proposed for parallel computers,owing to its many desirable properties such as regular and symmetrical structure,and strong scalability,among *** this paper,we first obtain an exact formula for the minimum wirelength to embed Qn3 into *** then propose a load balancing algorithm for embedding Qn3 into a square grid with minimum dilation and ***,we derive an O(N2)algorithm for embedding Qn3 into a gird with balanced communication,where N is the number of nodes in *** experiments are performed to verify the total wirelength and evaluate the network cost of our proposed embedding algorithm.

关键词： 3-ary n-cube embedding algorithm grid interconnection network

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Effects of zero-valent iron added in the flooding or drainage process on cadmium immobilization in an acid paddy soil

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Journal of Environmental Sciences 2024年第4期138卷 19-31页

作者： Hanbing Meng Shiwen Hu Zebin Hong Wenting Chi Guojun Chen kuan cheng QiWang Tongxu Liu Fangbai Li Kexue Liu Yang Yang Guangzhou Institute of Geochemistry Chinese Academy of SciencesGuangzhou 510640China National-Regional Joint Engineering Research Center for Soil Pollution Control and Remediation in South China Guangdong Key Laboratory of Integrated Agro-environmental Pollution Control and ManagementInstitute of Eco-environmental and Soil SciencesGuangdong Academy of SciencesGuangzhou 510650China School of Resources and Planning Guangzhou Xinhua UniversityGuangzhou 510310China University of Chinese Academy of Sciences Beijing 100049China

Zero-valent iron(ZVI)is a promising material for the remediation of Cd-contaminated paddy ***,the effects of ZVI added during flooding or drainage processes on cadmium(Cd)retention remain ***,Cd-contaminated paddy soil was incubated for 40days of flooding and then for 15 days of drainage,and the underlying mechanisms of Cd immobilization coupled with Fe/S/N redox processes were *** addition of ZVI to the flooding process was more conducive to Cd *** potential available Cd was detected by adding ZVI before flooding,which may be due to the increase in paddy soil pH and newly formed secondary Fe ***,the reductive dissolution of Fe minerals promoted the release of soil colloids,thereby increasing significantly the surface sites and causing Cd ***,the addition of ZVI before flooding played a vital role in Cd retention after soil *** contrast,the addition of ZVI in the drainage phase was not conducive to Cd retention,which might be due to the rapid decrease in soil pH that inhibited Cd adsorption and further immobilization on soil *** findings of this study demonstrated that Cd availability in paddy soil was largely reduced by adding ZVI during the flooding period and provide a novel insight into the mechanisms of ZVI remediation in Cd-contaminated paddy soils.

关键词： Paddy soil Zero-valent iron Cadmium Flooding and drainage Remediation

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Integration of Cytological Features with Molecular and Epigenetic Properties of Rice Chromosome 4

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Molecular Plant 2008年第5期1卷 816-829页

作者： Ben-Liang Yin Lan GUO Dong-Fen Zhang William Terzaghi Xiang-Feng Wang Ting-Ting Liu Hang He Zhu-kuan cheng Xing Wang Deng National Institute of Biological Sciences Beijing 102206 China Peking-Yale Jo-int Research Center-fo-r-Plant'Molecular-an-dAgrobiotechnology College of Life Sciences Peking University Beijing 100871 China Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing 100101 China Department of Molecular Cellular and Developmental Biology Yale University New Haven CT 06520-8104 USA Department of Biology Wilkes University Wilkes-Barre PA 18766 USA

It has been reported that rice chromosome 4 has eight major heterochromatic knobs within the heterochromatic half and that this organization correlates with chromosomal-level transcriptional activity. To better understand this chromosomal organization, we created a model based on the statistical distribution of various types of gene models to divide chromosome 4 into 17 euchromatic and heterochromatic regions that correspond with the cytological staining. Fluorescence in-situ hybridization （FISH） experiments using a set of bacterial artificial chromosome （BAC） clones from chromosome 4 placed all 18 clones in the region predicted by the model. Elevated levels of H3K4 di- and tri-methylation detected by chromatin-immunoprecipitation （CHIP） on chip were correlated with euchromatic regions whereas lower levels of these two modifications were detected in heterochromatic regions. Small RNAs were more abundant in the heterochromatic regions. To validate these findings, H3K4 trimethylation, H3K9 acetylation, H4K12 acetylation, and H3K9 di- and tri-methylation of 19 individual genes were measured by ChlP-PCR. Genes in heterochromatic regions had elevated H3K9 di- and tri-methylation while genes in euchromatic regions had elevated levels of the other three modifications. We also assayed cytosine methylation of these genes using the restriction enzymes McrBC, Hapll, and Msp I. This analysis indicated that cytosines of transposable elements and some genes located in heterochromatic regions were methylated while cytosines of the other genes were unmethylated. These results suggest that local transcriptional activity may reflect the organization of the corresponding part of the chromosome. They also indicate that epigenetic regulation plays an important role in correlating chromosomal organization with transcriptional activity.

关键词： chromosome organization FISH histone modification DNA methylation.

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缓冲区间有限条件下的作业车间调度方法

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东北大学学报（自然科学版） 2018年第12期39卷 1679-1684页

作者：曾程宽刘士新东北大学信息科学与工程学院辽宁沈阳110819

针对缓冲区间有限条件下的作业车间调度问题,以最小化make-span为目标建立了非线性混合整数规划模型,提出了基于邻域搜索的两阶段算法对问题进行求解.算法的第一阶段为迅速找到可行解,第二阶段为基于非连通图,通过邻域搜索对得到的可行... 详细信息

针对缓冲区间有限条件下的作业车间调度问题,以最小化make-span为目标建立了非线性混合整数规划模型,提出了基于邻域搜索的两阶段算法对问题进行求解.算法的第一阶段为迅速找到可行解,第二阶段为基于非连通图,通过邻域搜索对得到的可行解进行优化.针对benchmark算例进行测试并与已有的算法进行对比,验证了算法的有效性.对比分析发现,如果工件的加工时间符合均匀分布,当缓冲区间容量与工件数量的比例达到20%,缓冲区间大小对调度结果的影响将会迅速变小.

关键词：作业车间调度缓冲区间有限非连通图均匀分布

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求解存在运输空间约束多单元协作调度问题的拍卖算法

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控制与决策 2019年第4期34卷 689-698页

作者：曾程宽刘士新东北大学信息科学与工程学院沈阳110004

针对存在运输空间约束的多单元协作调度问题,提出合理的运输模式,建立非线性整数规划模型,对问题进行描述.通过拍卖的方式,将设备资源和运输资源分配给每一个工件,得到问题的可行解,并基于改进的(非)连通图对可行解进一步优化.通过拍卖... 详细信息

针对存在运输空间约束的多单元协作调度问题,提出合理的运输模式,建立非线性整数规划模型,对问题进行描述.通过拍卖的方式,将设备资源和运输资源分配给每一个工件,得到问题的可行解,并基于改进的(非)连通图对可行解进一步优化.通过拍卖方式,可以恰当地针对不同时间段的资源进行价值评估,从而提高资源的利用率,减少总的生产时间.拍卖过程分为两部分:车辆资源拍卖和设备资源拍卖.在整个拍卖过程中,车辆和设备分别扮演拍卖者,每个工件扮演竞拍者.通过对比实验,验证了所提出运输模式的合理性以及算法的有效性.

关键词：多单元协作调度运输空间约束合理的运输模式拍卖机制改进(非)连通图

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Resistance of esophageal cancer cells to paclitaxel can be reduced by knockdown of long noncoding RNA DDX11-AS1 through TAF1/TOP2A inhibition

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中国药理学与毒理学杂志 2019年第10期 781-782页

作者： CHEN Wan-ying XU cheng-cheng ZHAO cheng-kuan ZHANG Qiu-zhen CHEN Yun CHEN Si-hua LI Li SHE Yu-qi ZHENG Jie-ting ZHANG Shu-yao Department of Pharmacology Shantou University Medical College Guangzhou Red Cross Hospital affiliated to Ji-Nan University Medical Colege Department of Pharmacy Cancer Hospital of Shantou University Medical College

OBJECTIVE To define the role of the long noncoding RNA(lnc RNA) DDX11-AS1 in the progression of esophageal cancer(EC) with the involvement of PTX-resistant EC cells. METHODS First, EC and adjacent normal tissue samples were collected from 82 patients with EC, after which the expression levels of DDX11-AS1 in EC patients by conducting RT-q PCR,and the expression of TOP2A and TAF1 was determined in EC patients using immunohistochemistry. The relationship between DDX11-AS1, TOP2A and TAF1 was examined using RIP, Western blotting and Ch IP assays. The effect of DDX11-AS1 on the growth of PTX-inhibited tumors was confirmed using a tumor formation assay in nude mice. RESULTS DDX11-AS1, TOP2 A and TAF1 were highly expressed in EC tissues, and there was a positive correlation between the expression levels of DDX11-AS1 and TOP2A. DDX11-AS1 could promote TOP2A transcription via TAF1, and the knockdown of TOP2A or DDX11-AS1 could increase the sensitivity of EC cells to PTX. Knockdown of DDX11-AS1 can reduced the expression level of TOP2A and inhibited tumor growth. CONCLUSION DDX11-AS1 knockdown results in reduced resistance of EC cells to PTX by inhibiting TOP2A transcription via TAF1. Therefore, DDX11-AS1 knockdown could be a promising therapeutic strategy for EC.

关键词： DDX11-AS1 esophageal cancer paclitaxel TOP2A TAF1 resistance

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