检索结果-南通市图书馆

Climate change characteristics of Amur River

Water Science and Engineering 2013年第2期6卷 131-144页

作者： Lan-lan YU Zi-qiang XIA Jing-ku li Tao CAI River Basin Authority of liaoning Province State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering Institute of International Rivers Research Academy Hohai University Hydrological Bureau of liaoning Province

Unusually severe weather is occurring more frequently due to global climate change. Heat waves, rainstorms, snowstorms, and droughts are becoming increasingly common all over the world, threatening human lives and property. Both temperature and precipitation are representative variables usually used to directly reflect and forecast the influences of climate change. In this study, daily data （from 1953 to 1995） and monthly data （from 1950 to 2010） of temperature and precipitation in five regions of the Amur River were examined. The significance of changes in temperature and precipitation was tested using the Mann-Kendall test method. The amplitudes were computed using the linear least-squares regression model, and the extreme temperature and precipitation were analyzed using hydrological statistical methods. The results show the following： the mean annual temperature increased significantly from 1950 to 2010 in the five regions, mainly due to the warming in spring and winter; the annual precipitation changed significantly from 1950 to 2010 only in the lower mainstream of the Amur River; the frequency of extremely low temperature events decreased from 1953 to 1995 in the mainstream of the Amur River; the frequency of high temperature events increased from 1953 to 1995 in the mainstream of the Amur River; and the frequency of extreme precipitation events did not change significantly from 1953 to 1995 in the mainstream of the Amur River. This study provides a valuable theoretical basis for settling disputes between China and Russia on sustainable development and utilization of water resources of the Amur River.

关键词： climate change temperature precipitation extreme weather events Mann-Kendall test method," linear least-squares regression model," Amur River

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cloning and Characterization of Putative Hd6 Ortholog Associated with Zea mays L. Photoperiod Sensitivity

引用

Agricultural Sciences in China 2011年第1期10卷 18-27页

作者： ku li-xia li Si-yuan CHEN Xiao WU lian-cheng WANG Xin-tao CHEN Yan-hui College of Agronomy Henan Agricultural University Zhengzhou 450002 P.R.China

The photoperiod response of lowering is critical to the survival and successful reproduction in crops. The Hd6 gene, encoding a protein similar to the Arabidopsis α-subunit of CASEIN KINASE2α （CK2α） has been reported to affect flowering time through the photoperiodic pathway in rice. In this study, the maize ortholog, ZmHd6, has been cloned and its role in the photoperiodic pathway was investigated. ZmHd6 encodes 332 amino acids with six distinct domains： two CK2 active domains, a nuclear localization signal sequence, a N terminal domain, an ATP binding site, and an active site of serine/threonine protein kinase. ZmHd6 was constitutively expressed in the leaves and shoot apical meristem （SAM） with the highest expression in SAMs of plants with seven leaves under long and short day conditions. Delayed flowering time under long day （LD） conditions were observed in ZmHd6 overexpression transgenic Arabidopsis plants compared to the wild type. In transgenic Arabidopsis plants, ZmHd6 was expressed in a circadian oscillatory pattern, TOC1 peak expression was delayed, new GI, CO, and FT expressions reached to peak after 3 h while entering illumination period and oscillatory expression patterns of CO and FT were created during the dark phase. These results suggested that ZmHd6 might negatively regulate flowering time under LD conditions by delaying TOC1 peak expression and disrupting CO and FT expression in transgenic Arabidopsis plants.

关键词： maize (Zea mays L.) ZmHd6 photoperiod response expression

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The interaction mechanism and the functionality of yeast protein with hydrophilic and hydrophobic bioactive molecules

引用

Food Bioscience 2023年第2期52卷 990-999页

作者： Haili Sun Yifei Sun Xin Tang Yuanmeng Cui Demei Meng Yuyu Zhang ku li Hui Guo Hai Chen Rui Yang State Key Laboratory of Food Nutrition and Safety College of Food Science and EngineeringTianjin University of Science&TechnologyTianjin300457China Beijing Key Laboratory of Flavor Chemistry Beijing Technology and Business University(BTBU)Beijing100048China Angel Yeast Co.LTD. HubeiChina College of Food Science Southwest UniversityChognqing400715China

Yeast protein is a kind of yeast-source high-quality complete *** coexistence of bioactive molecules with yeast protein may influence its physicochemical *** study discussed the interaction mechanism of yeast protein with two bioactive molecules,the hydrophobic curcumin and the hydrophilic epigallocatechin gallate(EGCG).Results indicated that curcumin and EGCG could interact with yeast protein with different binding stoichiometric numbers(0.8109±0.0695 and 2.7248±0.2422)and binding constants((3.8152±0.0078)×10^(4) and(1.1875±0.0440)×10^(5)),*** EGCG and curcumin decreased theα-helix content while increased theβ-sheet proportion,and co-binding remarkably reduced theα-helix proportion relative to the single ligand *** co-binding of these two compounds decreased the association extent of the yeast protein,which in turn reduced the diameter of yeast protein-EGCG-curcumin *** binding of EGCG with yeast protein improved the thermal stability of ***,the co-binding improved the emulsification stability of yeast protein,and curcumin exhibited a more remarkable effect in improving the *** work provides a theoretical basis for clarifying the interaction mechanisms of hydrophobic/hydrophilic molecules with yeast protein,and extends the potential applications of the novel fungus protein sources for food function enhancement and bioactive molecule stabilization.

关键词： Yeast protein Bioactive ligands Non-covalent binding Stability Emulsification

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Integrating transcriptomic and proteomic analyses of photoperiod-sensitive in near isogenic maize line under long-day conditions

引用

Journal of Integrative Agriculture 2019年第6期18卷 1211-1221页

作者： SONG Xiao-heng TIAN Lei WANG Shun-xi ZHOU Jin-long ZHANG Jun CHEN Zan WU liu-ji ku li-xia CHEN Yan-hui College of Agronomy Henan Agricultural University/Synergetic Innovation Center of Henan Grain Crops/Key Laboratory of Physiological Ecology and Genetic Improvement of Food Crops in Henan ProvinceZhengzhou 450002P.R.China Henan Academy of Agricultural Science Zhengzhou 450002P.R.China

As a short-day plant species, maize requires an optimal photoperiod for inducing reproductive growth. However, there is a lack of information regarding photoperiod-induced changes in maize mRNA and protein levels. In this study, a photoperiod-insensitive maize inbred line and its near isogenic photoperiod-sensitive line were used. By integrating RNAbased transcriptomic and iTRAQ LC-MS/MS-based proteomic approaches, we generated a comprehensive inventory of the transcripts and proteins with altered abundances in response to a long photoperiod(LP) during growth stage transitions. We detected 22 000 transcripts in RNA-sequence runs and 5 259 proteins from an iTRAQ-based analysis. A weak correlation between mRNA-and protein-level changes was observed, suggesting the LP-induced transition between maize growth stages is largely regulated post-transcriptionally. Differentially expressed genes influenced by LP conditions were associated with several regulatory processes in both maize inbred lines, especially phosphate ion transport and the circadian rhythm. Additionally, 31 transcripts and six proteins related to photoperiodic flowering in maize were identified by comparing transcriptomic and proteomic data. This transcriptomic and proteomic analysis represents the first comprehensive and comparative study of gene/protein-level changes occurring in photoperiod-sensitive and-insensitive maize inbred lines during growth stage transitions under LP conditions.

关键词： development transition long photoperiod near isogenic line proteome transcriptome

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

西汉周应墓相关问题探析

引用

考古与文物 2024年第5期 110-114页

作者：李库汉景帝阳陵博物院

周应墓为西汉景帝阳陵陪葬墓之一,位于阳陵东区陪葬墓区域,其以列侯身份陪葬,设有独立的墓园,规格较高。墓葬为西汉前期典型的斜坡墓道洞室墓,以简单的木结构在墓室门前构筑的“前厅”。陪葬的塑衣式陶俑是墓主生前“家吏”“家臣”和... 详细信息

周应墓为西汉景帝阳陵陪葬墓之一,位于阳陵东区陪葬墓区域,其以列侯身份陪葬,设有独立的墓园,规格较高。墓葬为西汉前期典型的斜坡墓道洞室墓,以简单的木结构在墓室门前构筑的“前厅”。陪葬的塑衣式陶俑是墓主生前“家吏”“家臣”和“侍从”的替代品。推测该墓建于汉景帝中元二年(公元前148年),时代明确,为西汉阳陵陪葬墓的代表。

关键词：汉阳陵陪葬墓周应列侯墓葬形制

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Determination of the Photoperiod-Sensitive Inductive Phase in Maize with Leaf Numbers and Morphologies of Stem Apical Meristem

引用

Agricultural Sciences in China 2008年第5期7卷 554-560页

作者： WU lian-cheng WANG Tie-gu ku li-xia HUANG Qun-ce SUN Zhao-hui XIA Zhong-liang CHEN Yan-hui Agronomy College Henan Agricultural University Zhengzhou 450002 P.R.China Henan Institute of Science and Technology Xinxiang 453003 P.R.China Henan Provincial Key Laboratory of lon Beam Bio-Engineering Zhengzhou University Zhengzhou 450052 P.R.China

It is vital to determine the effective photoperiods of maize for making full use of tropical germplasm, which is the foundation for determining the effect of latitude and planting date on the development of photoperiod-sensitive maize cultivars. The objective of this study is to determine the photoperiod-sensitive inductive phase using reciprocal transfer between long- day （LD）（15 h d^-1） and short-day conditions （SD）（9 h d^-1）. For Huangzao 4 and CML288, days to tassel and pollen shedding were recorded, and stem apical meristems （SAM） were observed by a laser scanning confocal microscope. The results show that the seedlings are insensitive to photoperiod when they are very young （juvenile）. However, after this period, LD delays flowering and increases the leaf numbers below the inflorescence, and the length of the interval of the photoperiod-sensitive inductive phase is longer under LD conditions than under SD conditions. Transferred from SD to LD, plants show a sudden decrease in leaf numbers once sufficient SD has been received for flower commitment. While transferred from LD to SD, plants have a continuous increase in leaf numbers during the photoperiod sensitive inductive phase under LD conditions. At the same time, when plants are competent to flowers, the obvious morphology is the elongation of maize SAM. There is an obvious variance of the photoperiod sensitive phase under LD and SD conditions in different maize.

关键词： maize photoperiod flowering LSCM stem apical meristem (SAM) new full expansion leaf

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Emodin promoted pancreatic claudin-5 and occludin expression in experimental acute pancreatitis rats

引用

World Journal of Gastroenterology 2012年第17期18卷 2132-2139页

作者： Xian-Ming Xia Bang-ku li Shi-Mei Xing Hai-ling Ruan Department ofGastroenterology and Hepatology the Fourth Affiliated Hospital of Anhui Medical University Hefei 230022 Anhui ProvinceChina Department of Gastroenterology and Hepatology the First Affiliated Hospital of Anhui Medical University Hefei230022 Anhui Province China

AIM:To investigate the effect of emodin on pancreatic claudin-5 and occludin expression,and pancreatic paracellular permeability in acute pancreatitis(AP).METHODS:Experimental pancreatitis was induced by retrograde injection of 5% sodium taurocholate into the biliopancreatic *** was injected via the external jugular vein 0 or 6 h after induction of *** from sham operation and AP groups were injected with normal saline at the same *** of pancreas were obtained 6 or 12 h after drug *** morphology was examined with hematoxylin and eosin *** edema was estimated by measuring tissue water *** necrosis factor(TNF)-α and interleukin(IL)-6 level were measured by enzyme-linked immunosorbent *** paracellular permeability was assessed by tissue dye *** of pancreatic claudin-5 and occludin was examined by immunohistology,quantitative real-time reverse transcriptase polymerase chain reaction and western ***:Pancreatic TNF-α and IL-6 levels,wet/dry ratio,dye extravasation,and histological score were significantly elevated at 3,6 and 12 h following sodium taurocholate infusion;treatment with emodin prevented these changes at all time *** of claudin-5 and occludin was detected in rat pancreas,which was distributed in pancreatic acinar cells,ductal cells and vascular endothelial cells,*** taurocholate infusion significantly decreased pancreatic claudin-5 and occludin mRNA and protein levels at 3,6 and 12 h,and that could be promoted by intravenous administration of emodin at all time ***:These results demonstrate that emodin could promote pancreatic claudin-5 and occludin expression,and reduce pancreatic paracellular permeability.

关键词： Acute pancreatitis Paracellular permeability Emodin Claudin Occludin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Role of angiotensin receptor-neprilysin inhibitor in diabetic complications

引用

World Journal of Diabetes 2024年第5期15卷 867-875页

作者： Ying liu Cun-Yu Lu Yi Zheng Yu-Min Zhang ling-ling Qian ku-lin li Gary Tse Ru-Xing Wang Tong liu Department of Cardiology Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular DiseaseTianjin Institute of CardiologySecond Hospital of Tianjin Medical UniversityTianjin 300211China Department of Cardiology Xuzhou No.1 Peoples HospitalXuzhou 221005Jiangsu ProvinceChina Department of Cardiology Wuxi 9^(th)People’s Hospital Affiliated to Soochow UniversityWuxi 214062Jiangsu ProvinceChina Department of Cardiology Wuxi People’s Hospital Affiliated to Nanjing Medical UniversityWuxi 214023Jiangsu ProvinceChina School of Nursing and Health Studies Metropolitan UniversityHong Kong 999077China Kent and Medway Medical School Kent CT27NTCanterburyUnited Kingdom

Diabetes mellitus is a prevalent disorder with multi-system manifestations,causing a significant burden in terms of disability and deaths ***-tensin receptor-neprilysin inhibitor(ARNI)belongs to a class of medications for treating heart failure,with the benefits of reducing hospitalization rates and *** review mainly focuses on the clinical and basic investigations related to ARNI and diabetic complications,discussing possible physiological and molecular mechanisms,with insights for future applications.

关键词： Angiotensin receptor-neprilysin inhibitor Diabetic mellitus Complication

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

内蒙古土默特地区全化寺建筑彩画形制与颜料研究

引用

建筑学报 2024年第S01期 86-91页

作者：魏芸芝李丽李库内蒙古工业大学建筑学院呼和浩特010051 内蒙古自治区绿色建筑重点实验室呼和浩特010051

全化寺是官式与地方建筑彩画文化交流传播与发展演进的重要载体,其彩画呈现出蒙汉藏文化在地性耦合的特征,是研究清代土默特地区建筑彩画形成与演化脉络的典型样本。基于文献考据、实地勘察和信息采集,并通过类型剖析和颜料检测分析,揭... 详细信息

全化寺是官式与地方建筑彩画文化交流传播与发展演进的重要载体,其彩画呈现出蒙汉藏文化在地性耦合的特征,是研究清代土默特地区建筑彩画形成与演化脉络的典型样本。基于文献考据、实地勘察和信息采集,并通过类型剖析和颜料检测分析,揭示全化寺建筑彩画的形制演变特征和颜料种类,为土默特地区建筑彩画演化源流研究提供参考。

关键词：建筑彩画彩画形制颜料检测全化寺

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CDK5 in RNA Biology:New Clues that may Underlie Neuronal and Glial Diseases

引用

神经药理学报 2019年第Z1期 16-17页

作者： Andrew Bankston Izabela Suster Megan Allen li Wen-qi ku li YAO Bing FENG Yue Emory University Pharmacology and Chemical Biology

Cyclin-dependent kinase 5(CDK5) plays key roles in governing normal neuronal development and synaptic function though phosphorylation of serine and threonine residues on diverse protein targets. Emerging evidence also revealed that tightly controlled CDK5 activity is also crucial for the development of oligodendrocytes(OLs) and myelinogenesis,which provide protection and trophic support to brain neurons. Aberrant activation of CDK5 contributes to the pathogenesis of an increasing list of brain disorders,including Alzheimer's disease,stroke,schizophrenia,and epilepsy. However,molecular mechanisms that control CDK5 activity and its downstream effectors in neurons and OLs still remain vastly elusive. Activation of CDK5 depends on the available amounts of p35 or p39,two distinct non-cyclin protein activators. Our recent studies identified distinct mechanisms that regulate CDK5 activators in neurons and OLs during brain development. Here we report posttranscriptional mechanisms that control CDK5 activity in postnatal brain neurons and OLs by a functional interplay of RNA-binding proteins and microRNAs implicated in Alzheimer's disease and intellectual disability. Moreover,we discovered that CDK5-dependnent phosphorylation of RNA-binding proteins controls mRNA homeostasis and non-coding RNA biogenesis,including microRNAs and long non-coding RNAs in human neurons and OLs. These results provide the first evidence connecting CDK5 function with regulation of coding and non-coding transcriptome,which revealed new clues for CDK5 pathway function in normal and diseased brains.

关键词： CDK5 in RNA Biology:New Clues that may Underlie Neuronal and Glial Diseases RNA

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：