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Vibrational spectroscopy-are we close to finding a solution for early pancreatic cancer diagnosis?

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World Journal of Gastroenterology 2023年第1期29卷 96-109页

作者： krzysztof Szymoński Łukasz Chmura Ewelina Lipiec Dariusz Adamek Department of Pathomorphology Jagiellonian University Medical CollegeCracow 33-332Poland Department of Pathomorphology University Hospital in CracowCracow 31-501Poland M.Smoluchowski Institute of Physics Jagiellonian UniversityCracow 30-348Poland Department of Neuropathology Jagiellonian University Medical CollegeCracow 33-332Poland

Pancreatic cancer(PC)is an aggressive and lethal neoplasm,ranking seventh in the world for cancer deaths,with an overall 5-year survival rate of below 10%.The knowledge about PC pathogenesis is rapidly *** aspects of tumor biology,including its molecular and morphological heterogeneity,have been reported to explain the complicated“cross-talk”that occurs between the cancer cells and the tumor stroma or the nature of pancreatic ductal adenocarcinoma-associated neural ***,currently,there are no specific and sensitive diagnosis options for *** spectroscopy(VS)shows a promising role in the development of early diagnosis *** this review,we summarize recent reports about improvements in spectroscopic methodologies,briefly explain and highlight the drawbacks of each of them,and discuss available *** important aspects of spectroscopic data evaluation with multivariate analysis and a convolutional neural network methodology are *** conclude by presenting a study design for systemic verification of the VS-based methods in the diagnosis of PC.

关键词： Spectroscopic cancer diagnosis Raman spectroscopy Pancreatic cancer diagnosis DNA methylation Liquid biopsy biomarkers Convolutional neural networks

Bi-LSTM-Based Deep Stacked Sequence-to-Sequence Autoencoder for Forecasting Solar Irradiation and Wind Speed

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Computers, Materials & Continua 2023年第6期75卷 6375-6393页

作者： Neelam Mughees Mujtaba Hussain Jaffery Abdullah Mughees Anam Mughees krzysztof Ejsmont Department of Electrical and Computer Engineering COMSATS University IslamabadLahore Campus45550Pakistan School of Engineering and Technology National Textile UniversityFaisalabad37610Pakistan Department of Electrical Engineering Information Technology UniversityLahore54000Pakistan Department of Electrical Engineering GC UniversityFaisalabad38000Pakistan Faculty of Mechanical and Industrial Engineering Warsaw University of Technology02-524WarsawPoland

Wind and solar energy are two popular forms of renewable energy used in microgrids and facilitating the transition towards net-zero carbon emissions by ***,they are exceedingly unpredictable since they rely highly on weather and atmospheric *** microgrids,smart energy management systems,such as integrated demand response programs,are permanently established on a step-ahead basis,which means that accu-rate forecasting of wind speed and solar irradiance intervals is becoming increasingly crucial to the optimal operation and planning of *** this in mind,a novel“bidirectional long short-term memory network”(Bi-LSTM)-based,deep stacked,sequence-to-sequence autoencoder(S2SAE)forecasting model for predicting short-term solar irradiation and wind speed was developed and evaluated in *** create a deep stacked S2SAE prediction model,a deep Bi-LSTM-based encoder and decoder are stacked on top of one another to reduce the dimension of the input sequence,extract its features,and then reconstruct it to produce the *** of the proposed deep stacked S2SAE forecasting model were optimized using the Bayesian optimization ***,the forecasting performance of the proposed Bi-LSTM-based deep stacked S2SAE model was compared to three other deep,and shallow stacked S2SAEs,i.e.,the LSTM-based deep stacked S2SAE model,gated recurrent unit-based deep stacked S2SAE model,and Bi-LSTM-based shallow stacked S2SAE *** these models were also optimized and modeled in *** results simulated based on actual data confirmed that the proposed model outperformed the alternatives by achieving an accuracy of up to 99.7%,which evidenced the high reliability of the proposed forecasting.

关键词： Deep stacked autoencoder sequence to sequence autoencoder bidirectional long short-term memory network wind speed forecasting solar irradiation forecasting

Epithelioid hemangioendothelioma of the liver as a rare indication for liver transplantation

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World Journal of Gastroenterology 2014年第32期20卷 11333-11339页

作者： Piotr Remiszewski Ewa Szczerba Piotr Kalinowski Beata Gierej krzysztof Dudek Mariusz Grodzicki Marcin Kotulski Rafa Paluszkiewicz Waldemar Patkowski krzysztof Zieniewicz Marek Krawczyk Department of General Transplant and Liver Surgery Medical University of Warsaw 00-097 Warsaw Poland Department of Anatomopathology Medical University of Warsaw 00-097 Warsaw Poland

AIM: To investigate the indications and outcomes of liver transplantation for hepatic epithelioid hemangioendothelioma (HEHE).

关键词： Hemangioendothelioma Liver transplantation Liver malignancies Transplantation results Transplantation indications

Degradable and Recyclable Polymers by Reversible Deactivation Radical Polymerization

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CCS Chemistry 2022年第7期4卷 2176-2211页

作者： Michael R.Martinez krzysztof Matyjaszewski Department of Chemistry Carnegie Mellon UniversityPittsburghPA 15213

Reversible deactivation radical polymerization(RDRP)provides unprecedented control over polymer composition,size,functionality,and *** materials,such as linear polymers,star polymers,branched polymers,graft polymers,polymer networks,and hybrid materials,have been prepared by *** ability to control polymer topology also enabled precision synthesis of well-defined polymer topologies with degradable functional groups located at specific locations along a polymer *** review outlines progress in the synthesis of degradable polymers designed by RDRP,organized by topology and synthetic *** progress in the depolymerization of polymers using RDRP mechanisms is highlighted and critically discussed.

关键词： reversible deactivation radical polymerization recycling deg radable polymer self-healing depolymerization atom transfer radical polymerization addition-fragmentation radical transfer nitroxide-mediated polymerization

A multistage collaborative 3D GIS to support public participation

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International Journal of Digital Earth 2015年第3期8卷 212-234页

作者： Yingjie Hu Zhenhua Lv Jianping Wu krzysztof Janowicz Xizhi Zhao Bailang Yu Key Laboratory of Geographic Information Science Ministry of EducationEast China Normal UniversityShanghaiPR China Department of Geography University of California Santa BarbaraSanta BarbaraCAUSA Shanghai Key Lab for Urban Ecological Processes and Eco-Restoration East China Normal UniversityShanghaiPR China

This paper presents a collaborative 3D GIS to support public *** that public-involved decision-making is often a multistage process,the proposed system is designed to provide coherent support for collaborations in the different *** differentiate ubiquitous participation and intensive participation and identify their suitable application *** proposed system,then,supports both of the two types of participation by providing synchronous and asynchronous collabora-tion *** the concept of Digital Earth,the proposed system also features a virtual globe-based user *** an interface integrates a variety of data,functions,and services into a unified virtual environment which is delivered to both experts and public participants through the *** system has been designed as a general software framework and can be tailored for specific *** this study,we demonstrate it using a scene modeling case and provide a preliminary evaluation toward its usability.

关键词： public participation multistage decision-making 3D visualization virtual globe online collaboration Digital Earth

A RESTful proxy and data model for linked sensor data

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International Journal of Digital Earth 2013年第3期6卷 233-254页

作者： krzysztof Janowicz Arne Broring Christoph Stasch Sven Schade Thomas Everding Alejandro Llaves Department of Geography University of CaliforniaSanta BarbaraCAUSA North Initiative for Geospatial Open Source Software MunsterGermany Faculty ITC University of TwenteEnschedeTheNetherlands Institute for Geoinformatics University of MunsterMunsterGermany Joint Research Centre Institute for Environment and SustainabilityIspraItaly

The vision of a Digital Earth calls for more dynamic information systems,new sources of information,and stronger capabilities for their *** networks have been identified as a major information source for the Digital Earth,while Semantic Web technologies have been proposed to facilitate *** far,sensor data are stored and published using the Observations&Measurements standard of the Open Geospatial Consortium(OGC)as data *** the advent of Volunteered Geographic Information and the Semantic Sensor Web,work on an ontological model gained importance within Sensor Web Enablement(SWE).In contrast to data models,an ontological approach abstracts from implementation details by focusing on modeling the physical world from the perspective of a particular *** restrict the interpretation of vocabularies toward their intended *** ongoing paradigm shift to Linked Sensor Data complements this *** questions have to be addressed:(1)how to refer to changing and frequently updated data sets using Uniform Resource Identifiers,and(2)how to establish meaningful links between those data sets,that is,observations,sensors,features of interest,and observed properties?In this paper,we present a Linked Data model and a RESTful proxy for OGC’s Sensor Observation Service to improve integration and inter-linkage of observation data for the Digital Earth.

关键词： Digital Earth geospatial data integration spatial data infrastructure earth observation data exchange models linked data semantic enablement

Battle at the entrance gate:CIITA as a weapon to prevent the internalization of SARS-CoV-2 and Ebola viruses

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Signal Transduction and Targeted Therapy 2020年第1期5卷 226-227页

作者： Rafal Butowt krzysztof Pyrc Christopher S.von Bartheld L.Rydygier Collegium Medicum Nicolaus Copernicus UniversityBydgoszczPoland Virogenetics Laboratory of Virology Malopolska Centre of BiotechnologyJagiellonian UniversityGronostajowa 7a30-387 KrakowPoland Center of Biomedical Research Excellence in Cell Biology University of NevadaReno School of MedicineRenoNVUSA

In a recent paper in Science,Bruchez et al.1 provide new insights how host cells can fight virus *** show that an MHC class II transactivator(CIITA)—which normally operates as part of the interferon(IFN)-stimulated i... 详细信息

关键词： CIITA al interferon

Concentration of Selected Elements in the Tissues of the Knee Joint

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Biomedical and Environmental Sciences 2020年第10期33卷 807-811页

作者： BABUSKA-ROCZNIAK Magdalena BRODZIAK-DOPIERALA Barbara MITKO krzysztof CIPORA Elzbieta ROCZNIAK Wojciech The Jan Grodek State University in Sanok Medical Institute38-500 SanokPoland Department of Toxicology and Bioanalysis Faculty of Pharmaceutical ScienceMedical University of Silesia41-200 SosnowiecPoland Central Mining Institute The Laboratory of Water and Sewage Analyses40-166 KatowicePoland

The remodeling processes that occur in bone tissue allow for proper functioning and can lead to the inclusion of additional elements,including toxic ones,in the remodeled *** condition in turn affects the metabolic processes in the bond,which may result in disturbances to the bone-joint system,as manifested by changes in bone tissue and other organs[1].

关键词： organs remodeling bone

Effects of a variety of cutting fluids administered using the minimum quantity lubrication method on the surface grinding process for nickel-based alloys

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2017年第9期18卷 728-740页

作者： Ryszard WOJCIK krzysztof NADOLNY Instimte of Machine Tools and Production Engineering Lodz University of Technology Stefanowskiego 1/15 90-924 Lodz Poland Department of Production Engineering Koszalin University of Technology Raclawicka 15-17 75-620 Koszalin Poland

This paper presents the characteristics of nickel-based alloys, alongside their division into groups, and describes thefeatures that make such materials difficult to grind. The possibilities of exerting a positive influence upon machining conditions,especially through the proper application of grinding fluids, are briefly presented. Both the precise methodologies for, and theresults of, the experimental tests carried out on flat surfaces are also detailed. The aim of these tests was to determine the influenceof the application of two types of grinding liquid （Ecocut Mikro Plus 82 and Biocut 3000） upon the grinding force values andsurface roughness of the machined workpieces made from three nickel alloys （Nickel 201, INCONEL~ alloy 600, and MONEL^alloy 400）. An additional goal of the tests was to determine the influence of grinding wheel structure on the course and results ofthe machining process. The results indicate that the physical and chemical properties of Biocut 3000 enabled the most advanta-geous properties of the machined surface roughness, alongside a simultaneous increase in grinding power, when compared to theresults when applying Ecocut Mikro Plus 82. The results showed an almost inversely proportional dependence upon the specifictangential grinding force Ft＇ and arithmetic mean deviation of the surface profile Ra values, especially in cases of machining Nickel201 and INCONEL alloy 600. The original traverse grinding methodology used in the tests made it possible to assess the changesof the grinding conditions within the conventionally selected zones.

关键词： Nickel-based alloys Surface grinding Minimum quantity lubrication Hard-to-cut materials Grinding force Surface roughness