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登陆稳定岛

物理 2015年第8期44卷 530-531页

作者：周书华 Yuri Ts.Oganessian krzysztof P.Rykaczewski 中国原子能科学研究院

在20世纪60年代,William Myers与Wladyslaw,以及Victor Viola Jr与Glenn Seaborg两个研究组独立地预言：在核素图中所谓的稳定岛上存在着重核。

关键词：幻数中子数理论预言壳层核素图质子数超重核 Victor α衰变复合核

基质初始浓度对SFBR工艺去除营养物的影响

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环境科学与技术 2006年第8期29卷 3-5页

作者：邵友元 krzysztof W.Szewczyk 李卫黄光斗孙俊逸湖北工业大学化学与环境工程学院武汉430068 华沙理工大学化学工程系

采用序半连续反应器就新鲜废水中COD/N比对COD、氮化合物去除效率和微生物生长的影响进行了研究。结果表明,新鲜废水中的COD/N比对COD和总氮去除率有明显的影响。当COD/N比由2.5增至12.5时,COD去除率由44.0%增至75.8%,总氮去除率从63.4... 详细信息

采用序半连续反应器就新鲜废水中COD/N比对COD、氮化合物去除效率和微生物生长的影响进行了研究。结果表明,新鲜废水中的COD/N比对COD和总氮去除率有明显的影响。当COD/N比由2.5增至12.5时,COD去除率由44.0%增至75.8%,总氮去除率从63.4%增至99.8%,然而,加料废水中COD/N比对微生物生长没有明显的影响。用一组涉及多个微生物反应的动力学模型,分析了COD/N比对同时去除碳、氮化合物效率和微生物生长的影响。

关键词：序半连续式反应器活性污泥硝化反硝化动力学

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波兰艺术公园

设计 2013年第5期26卷 50-51页

作者： Jacob krzysztof Ingarden

这座建筑希望在波兰的克拉科夫增加一个新的文化机构，并融入城市既有的“血脉”之中。建筑在一片残垣断壁的老建筑中建起，带来了新的空间秩序，这是一座19世纪的赛马场遗留下来的旧建筑，近年用作剧院的工作间和仓库。

关键词：波兰公园艺术老建筑空间秩序旧建筑赛马场工作间

Influence of Alginates on Tube Nerve Grafts of Different Elasticity - Preliminary <i>in Vivo</i>Study

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Journal of Biomaterials and Nanobiotechnology 2012年第1期3卷 20-30页

作者： Dariusz Szarek Jadwiga Laska Wlodzimierz Jarmundowicz Stanislaw Blazewicz Pawel Tabakow krzysztof Marycz Zdzislaw Wozniak Janusz Mierzwa Department of Biomaterials AGH University of Science and Technology Krakow Poland Department of Neurosurgery Wroclaw Medical University Wroclaw Poland Department of Neurosurgery Wroclaw University Hospital Wroclaw Poland Department of Pathomorphology Wroclaw Medical University Wroclaw Poland Labora- tory of Electron Microscopy Studies Wroclaw University of Environmental and Life Sciences Wroclaw Poland

This preliminary research project has been conducted to evaluate different elastic polymer materials in terms of their applicability in peripheral nerve regeneration. Poly(tetrafluoroetylene-co-difluorovinylidene-co-propylene), poly(L-lactide-co-D,L-lactide), and polyurethane were used for the manufacture of tubular implants. Alginate sodium gel and fibers were used as a scaffold to fill in tube nerve grafts and enhance nerve regeneration. The tubes were implanted to reconstruct a 10 mm gap in the sciatic nerve in rats. After 3, 7, 14, 28 days the tubes were retrieved for histological examination. Among tested tubes polyurethane implants were found to be the most suitable because of their mechanical and surgical properties. Other tested implants were found to be unfavorable due to their inappropriate rigidity, elasticity or surgical convenience. Alginate transformation into dense gel form was observed that hindered inner tube space cellular colonization. In consequence of this transformation nerve regeneration was inhibited inside tube nerve grafts. Histological examination showed massive colonization of the implants with Schwann cells, and growth of new axons was found within Schwann cells growing on tubes external surface. Appropriate time rates for alginate gelation and dissolving must be determined to allow undisturbed tissue growth and maturation.

关键词： Tube Nerve Grafts Polyurethane Polylactide Terpolimer Sodium Alginate Sciatic Nerve in Vivo

Phenylacetylglutaminate and Phenylacetate in Combination Upregulate VDUP1, Cause Cell Cycle Blockade and Apoptosis in U87 Glioblastoma Cells

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Journal of Cancer Therapy 2012年第3期3卷 192-200页

作者： Sonali S. Patil Stanislaw R. Burzynski Emilia Mrowczynski krzysztof Grela Sridar V. Chittur Center for Functional Genomics University at Albany Rensselaer USA. Department Cell and Molecular Biology Burzynski Research Institute Stafford USA

Phenylacetylglutaminate (PG) and Phenylacetate (PN) are metabolites of Phenylbutyrate (PB) and are constituents of antineoplaston AS2-1. These are sodium salts of amino acid derivative and carboxylic acid that inhibit the growth of neoplastic cells without growth inhibitory effect in normal cells. The aim of this study was to identify molecular pathways involved in the anti-proliferative effect of antineoplastons. Using a total human genome microarray we have found that 1) Vitamin D3 upregulated protein (VDUP1) is significantly upregulated in response to PG and PN in the U87 glioblastoma cells;2) Isobologram analysis shows that PG and PN act in an additive or synergistic manner to effectively suppress proliferation of U87 cells;3) PG and PN cause cell cycle arrest, changes in expression of several cell cycle genes and suppress expression and activity of the G2/M checkpoint kinase, CHK1. The multiple cellular targets possibly make these compounds effective anti-proliferative agents. We propose that PG and PN in combination target important cellular pathways and upregulate VDUP1 leading to detachment-induced apoptosis in cancer cells.

关键词： Glioblastoma VDUP1 Phenylacetylglutaminate Phenylacetate Apoptosis Drug Combination

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微生物浓度对SFBR工艺去除营养物的影响

环境科学与技术 2006年第7期29卷 1-3页

作者：邵友元 krzysztof W.Szewczyk 李卫黄光斗孙俊逸湖北工业大学化学和环境工程学院武汉430068 华沙理工大学化学工程系

采用序半连续式反应器(SequentialFed-batchReactor,简称SFBR,下同。)就不同微生物初始浓度对人工配置废水营养物去除效率的影响进行了研究。探讨了微生物初始浓度对COD、氮化合物(NH4-N和NO3-N)除去和微生物生长的影响。结果表明,当微... 详细信息

采用序半连续式反应器(SequentialFed-batchReactor,简称SFBR,下同。)就不同微生物初始浓度对人工配置废水营养物去除效率的影响进行了研究。探讨了微生物初始浓度对COD、氮化合物(NH4-N和NO3-N)除去和微生物生长的影响。结果表明,当微生物初始浓度为140.4g/L时,COD有最高除去率(69.5%)。当微生物初始浓度≥46.8g/L,总氮除去率可达100%。菌体初始浓度对废水中营养物的去除有利。过高浓度的微生物生长,受营养物和供氧的限制。用一组涉及多个微生物反应的动力学模型,分析了微生物初始浓度对同时去除碳、氮化合物效率和微生物生长的影响。

关键词：序半连续式反应器活性污泥硝化反硝化