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Influences of ascorbic acid and gibberellic acid in alleviating effects of salinity in Petunia under in vitro

Phyton-International Journal of Experimental Botany 2019年第1期88卷 15-23页

作者： krupa-małkiewicz m B Smolik m Sędzik Department of Plant Genetics Breeding and BiotechnologyWest Pomeranian University of Technology in SzczecinSłowackiego str.71-434 SzczecinPoland Department of Plant Physiology and Biochemistry West Pomeranian University of Technology in SzczecinSłowackiego str.71-434 SzczecinPoland

Salinity is one of the abiotic stresses that limits the growth and productivity of many crops.A possible survival strategy for plant under saline conditions is to use compounds that could minimize the harmful effects of salt stress on the plant development.The objective of the presented study was to investigate the effect of exogenous ascorbic acid(ASA)with or without gibberellic acid(GA3)on key growth and biochemical parameters in two petunia cultivars‘Prism Rose’and‘Prism White’under saline(150 mm NaCl)and non-saline in vitro condition.Nodal cutting with an axillary buds were used as explants.Application of 1 mm ascorbic acid with or without 0.05 mm gibberellic acid into the mS medium stimulated the length of shoots and the number of new shoots of‘Prism Rose’;whereas,it decreased the root length and the number of roots of both‘Prism Rose’and‘Prism White’under non-saline condition.The addition of ascorbic acid with or without gibberellic acid into the mS medium under saline condition,increased the length of plants and the number of new shoots,but did not affect their root number and length.NaCl treatments increased the proline content and lipid peroxidation which was indicated by the accumulation of malondialdehyde(mDA).The study revealed a correlation between chlorophylls a and b content and the leaf pigmentation intensity–parameter a*.Addition of 1 mm ascorbic acid with 0.05 mm gibberellic acid into the mS medium plays a protective role in salinity tolerance by improving the shoot growth and the development as well as increasing the activities of the antioxidant enzymes and other antioxidant substances.

关键词： AsA GA3 micropropagation Petunia x atkinsiana D.Don Salinity

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Reviving Fertility:Phytochemicals as Natural Allies in the Fight against Non-genetic male Infertility

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Clinical Complementary medicine and Pharmacology 2024年第1期4卷 112-128页

作者： Vivek P.Chavda Shreya S Sonak Pankti C.Balar krupa Vyas Pranali Palandurkar Komal mule Krishna Patel Vivek Hala Dixa A.Vaghela Devarshi Acharya Akta Vaishnav Jimil Gandhi Vasso Apostolopoulos Department of Pharmaceutics and Pharmaceutical Technology L M College of PharmacyAhmedabadGujarat 380008India Bharati Vidyapeeth University’s Poona College of Pharmacy ErandwaneKothrudPune 411038India Pharmacy section L M College of PharmacyAhmedabadGujarat 380008India University Department of Pharmaceutical Sciences R.T.m Nagpur 440033India Department of Pharmaceutics Khyati College of PharmacyAhmedabad 380009India IICISST Sardar Patel UniversityVallabh Vidyanagar 388120India Institute for Health and Sport Immunology and Translational ResearchVictoria UniversityMelbourneVIC 3030Australia Immunology Program Australian Institute for Musculoskeletal ScienceMelbourneVIC 3021Australia

Background:male infertility poses a growing challenge to the healthcare system,with its prevalence on the rise.Unhealthy lifestyle,food,and addictions such as smoking,alcoholism,etc.accelerate the occurrence.While several approaches are being investigated to prevent and treat this condition,each therapeutic approach has its drawbacks.Traditional medications continue to play a crucial role in the healthcare system.In recent years,there has been a shift towards determining the efficacy of phytochemicals(or,herbal drugs)as remedies.Objective:To evaluate the effect of various herbs,plant,metabolites,or a part of plant in management of non-genetic male infertility.methods:The male infertility-associated keywords were searched in Pubmed,excluding those non-English writen papers.A total of 146 pertinent and closely connected records were included for full reading and inclusion in the systemic evaluation.Results:The manuscript focuses on individual herbal drug components,their active ingredients,their role in improving the condition and quality of life,and decreasing the prevalence of male infertility.Conclusion:Herbal medicinal plants show promising outcomes to treat male infertility.Herbal alternatives are appealing and have regained popularity.The future holds promise for some of these herbal treatments to advance with many showing improved outcomes in males with infertility issues.

关键词： male infertility Plant-based management Phytochemical Herbal drug Traditional Chinese medicine

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How rotational speed of planetary ball mill and polymer load influence the performance and water vapor sorption in solid dispersions composed of tadalafil and soluplus

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Particuology 2023年第2期73卷 37-46页

作者： Karol Kubat Anna krupa Witold Brniak Agnieszka Węgrzyn Dorota majda Agata Bogdał Hubert Harańczyk Department of medical Physics Faculty of PhysicsInstitute of PhysicsJagiellonian UniversityCracowPoland Department of Pharmaceutical Technology and Biopharmaceutics Faculty of PharmacyCollegium MedicumJagiellonian UniversityCracowPoland Faculty of Chemistry Jagiellonian UniversityCracowPoland

The presence of residual water may deteriorate the performance of amorphous solid dispersions prepared by ball milling,affecting molecular mobility,crystallinity,particle size and finally,the drug dissolution rate.As the stability of these metastable systems depend on both formulation and process variables,the aim of this study was to assess for the first time,the impact that the polymer load and the rotational speed applied upon high energy ball milling could have on the performance of binary co-milled solid dispersions composed of tadalafil(a hydrophobic crystalline drug)and Soluplus(an amphiphilic,hygroscopic amorphous polymer).Each of these variables was tested at three levels.Scanning electron microscopy,laser diffraction and X-ray powder diffraction were used to analyze morphology,particle size distribution and crystallinity of ball milled formulations respectively.Dissolution studies were also carried out.Advanced tools of applied physics,namely solid state 1H NmR and relaxometry were used to assess the structure and water mobility upon gaseous phase hydration on storage.It was shown that both tested variables determined the particle size of the formulation.When the rotational speed of 400 rpm was used,all solid dispersion were XRD-amorphous,but to ensure the immediate release of tadalafil its micellar solubilization in Soluplus was necessary.While the formulation was exposed to water vapor,the hydration level increased with an increasing polymer load as well.Hence,the rotational speed governed the space available for the adsorption of water molecules and their organization in a monolayer or multilayers.Such behavior may have impact on the kinetics of the amorphous drug recrystallization,and finally deteriorate its dissolution.

关键词： Tadalafil Soluplus Solid dispersion Relaxation time milling NmR

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Site Selective Excitation and Energy Transfer in LiKGdF_5 Crystal Co-doped with Er^(3+) and Tb (3+)

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Journal of Rare Earths 2004年第1期22卷 22-26页

作者：尹民 Khaidukov N m krupa J C Structure Research Laboratory Kurnakov Institute of General and Inorganic Chemistry Institut de Physique Nucléaire

Crystals of LiKGdF 5∶Er 3+, Tb 3+ grown by the hydrothermal synthesis technique with concentrations of 2% and 0.4% were analysed. By using site selective excitation measured at low temperature, luminescence and excitation spectra from Er 3+ and Tb 3+ ions embedded in LiKGdF 5 were clearly separated. The lifetimes of the emitting levels 4S 3/2 of Er 3+ and 5D 4 of Tb 3+ were also determined. Following the site selective spectroscopy study, the dominant energy transfer process from Tb 3+ to Er 3+ in the crystal was then investigated via transient experiments.

关键词： optics condensed matter physics energy transfer luminescence LiKGdF 5∶Er3+, Tb3+ rare earths

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格位选择激发下Eu[Cr_(0.1)Al_(0.9)(OH)_6mo_6O_(18)]·11H_2O的光谱特性

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光谱学与光谱分析 2005年第3期25卷 326-328页

作者：尹民 krupa J C Yusov A B Fedosseev A m 中国科学技术大学结构分析重点实验室物理系安徽合肥230026 原子核物理研究所 orsaycedex法国91406 物理化学研究所 moscow俄罗斯119991

详细研究了Eu[Cr0. 1Al0 . 9(OH) 6mo6O18]·11H2 O中Eu3 + 的发光特性。通过对实验结果的分析 ,确定了体系中Eu3 + 离子有 3种发光中心 ,其中一种占主导地位。样品中存在的Eu3 + 到Cr3 + 的能量传递 ,也发生在这个中心。利用低温下的... 详细信息

详细研究了Eu[Cr0. 1Al0 . 9(OH) 6mo6O18]·11H2 O中Eu3 + 的发光特性。通过对实验结果的分析 ,确定了体系中Eu3 + 离子有 3种发光中心 ,其中一种占主导地位。样品中存在的Eu3 + 到Cr3 + 的能量传递 ,也发生在这个中心。利用低温下的格位选择激发 ,成功地分离了 3种发光中心的发射光谱。结果显示 ,主要发光中心的格位对称性为C1,与以前的研究结果一致 ;另外两种发光中心则具有较高的对称性。在共振激发条件下 ,测量了不同发光中心在低温下的荧光衰减曲线 ,拟合计算给出中心 1(主要发光中心 )和中心 3的5D0能级的寿命分别为 107和 599μs,相差近 6倍。说明中心 3的对称性比中心 1高 ,和从光谱测量得到的结论一致。

关键词：发光中心 Eu^3+ OH 对称性荧光衰减 Cr^3+ 研究结果低温实验结果

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Green and red Anti-Stokes emission of U^(3+): LaCl_3 produced by infrared laser

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原子与分子物理学报 2001年第1期18卷 4-6页

作者： YIN min DEREN P J JOUBERT m F krupa J C University of Science and Technology of China Institute of Low Temperature and Structure Researches. PO Box 937 Universite Claude Bernard Lyon 1 Groupe de Radiochimie Institut de Physique Nucleaire

Anti-Stokes green and red emission from U3+: LaCl3 can be produced by infrared laser excitation at 975.3 nm, 977.7 nm and 979.4 nm at 8K. The upconversion luminescence intensity dependence upon the excitation laser power was measured and analyzed. The results show that depending on the excitation wavelength, the mechanisms responsible for the upconversion process are two-photon absorption and excited-state absorption.

关键词：非燃烧发光三氯化镧晶体红外激光

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Reversal of the magnetic Nanofilms and Data Recording by Spin Current

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Journal of Physical Science and Application 2015年第1期5卷 14-23页

作者： mykola m. krupa Institute of magnetism National Academy of Science of Ukraine Kiev 03143 Ukraine

The article presents the results of experimental studies of the physical mechanisms and magnetic switching dynamics of films with one or two magnetic nanolayers under an irradiation picosecond and femtosecond laser pulses and also the samples of data recording devices on the spin storage medium are described. The study used a film with perpendicular anisotropy (Tb22Co5Fe73/Pr6O11/Tb19Co5Fe76, Tb25Co5Fe70/Al2O3, Tb22Co5Fe73, Tb19Co5Fe76) and films planar single-axis magnetic anisotropy (Co80Fe20/Pr6O11/Co30Fe70). The magnetic switching of magnetic layers under action the magnetic field of a spin current is the most important for practical use in elements of spintronic. The spin current can also be realized using short electrical pulses. On the basis of this mechanism, the high-speed recording of information on the spin carrier has been realized.

关键词：数据记录设备纳米薄膜自旋流磁性层逆转飞秒激光脉冲垂直各向异性物理机制

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Cross-section measurements for 58,60,61Ni(n,α)55,57,58Fe reactions in the 4.50-5.50 meV neutron energy region

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Chinese Physics C 2020年第11期44卷 138-149页

作者：江浩雨崔增琪胡益伟刘杰陈金象张国辉 Yu.m.Gledenov E.Sansarbayar G.Khuukhenkhuu L.krupa I.Chuprakov State Key Laboratory of Nuclear Physics and Technology Institute of Heavy Ion PhysicsPeking UniversityBeijing 100871China Frank Laboratory of Neutron Physics Joint Institute for Nuclear ResearchDubna 141980Russia Nuclear Research Centre National University of MongoliaUlaanbaatar 210646Mongolia Flerov Laboratory of Nuclear Reactions Joint Institute for Nuclear ResearchDubna 141980Russia Institute of Experimental and Applied Physics Czech Technical University in PragueHorska 3a/22Prague 212800Czech Republic

The cross sections at 5 energy points of the 58Ni(n,α)55Fe reaction were measured in the 4.50 meV≤En≤5.50 meV region while those for the 60Ni(n,α)57Fe and 61Ni(n,α)58Fe reactions were measured at En=5.00 and 5.50 meV using the 4.5 mV Van de Graaff accelerator at Peking University.A gridded twin ionization chamber(GIC)was used as the detector,and enriched 58Ni,60Ni,and 61Ni foil samples were prepared and mounted at the sample changer of the GIC.Three highly enriched 238U3O8 samples inside the GIC were used to determine the relative and absolute neutron fluxes.The neutron energy spectra were obtained through unfolding the pulse height spectra measured by the EJ-309 liquid scintillator.The interference from the low-energy neutrons and impurities in the samples has been corrected.The present data of the 60Ni(n,α)57Fe reaction are the first measurement results below 6.0 meV,and those of the 61Ni(n,α)58Fe reactions are the first measurement results in the meV region.The present results have been compared with existing measurements,evaluations,and TALYS-1.9 calculations.

关键词： 58,60,61Ni(n,α)55,57,58Fe reactions cross sections GIC

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Value within otolaryngology:Assessment of the cost-utility analysis literature

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2016年第1期2卷 -页

作者： krupa R. Patel David J. Phillips Jason m. Leibowitz Theresa Scognamiglio Victoria E. Banuchi William I. Kuhel David I. Kutler marc A. Cohen Weill Cornell medical College New York NY 10065 USA Department of 0tolaryngology-Head and Neck Surgery New York Presbyterian Hospital/Weill Cornell Medical Center New York NY 10065 USA Department of 0tolaryngology-Head and Neck Surgery University of Miami Miami FL 33136 USA Department of Pathology&Laboratory medicine New York Presbyterian Hospital/Weill Cornell Medical Center New York NY 10065 USA

UNASSIGNED:To assess the characteristics and quality of cost utility analyses (CUA) related to otolaryngology within the CEA registry and to summarize their collective results.;UNASSIGNED:All cost-utility analyses published between 1976 and 2011 contained in the Cost-Effectiveness Analysis Registry (CEA Registry) were evaluated. Topics that fall within the care of an otolaryngologist were included in the review regardless of the presence of an otolaryngologist author. Potential associations between various study characteristics and CEA registry quality scores were evaluated using the Pearson product moment correlation coefficient.;UNASSIGNED:Sixty-one of 2913 (2.1%) total CUA publications screened were related to otolaryngology. Eighteen of 61 (29.5%) publications included an otolaryngologist as an author. Fourteen studies agreed on the cost effectiveness of at least unilateral cochlear implantation and six of seven (85.7%) studies demonstrated the cost effectiveness of continuous positive airway pressure (CPAP) for obstructive sleep apnea (OSA). Forty-six percent (28 of 61) of all manuscripts were published between 2008 and 2011. A more recent publication year was associated with a higher CEA registry quality score while the presence of an otolaryngologist author and journal impact factor had no significant correlation with the quality of the CUA.;UNASSIGNED:Based on current evidence in the CEA registry, unilateral cochlear implantation for hearing loss and CPAP for OSA are both cost-effective therapeutic interventions. Although CUAs in otolaryngology have increased in quantity and improved in quality in more recent years, there is a relative lack of CUAs in otolaryngology in comparison to other subspecialties.

关键词： Cost-utility analysis

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LiKGdF_5∶Er^(3+),Sm^(3+)单晶的VUV光谱和量子剪裁

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核技术 2004年第12期27卷 909-913页

作者：董宁徐美张慰萍尹民陶冶 makhov V N Khaiduhov N m krupa J C 中国科学技术大学结构分析重点实验室物理系中国科学院高能物理研究所同步辐射实验室 Lebedev Physical Institute moscow 117924 Russia Kurnakov Inshote of General and Inorganic Chemistry moscow 117907 Russia Institude Pbysiquc Nucléaire CNRS-IN2P3 91406 Orsay CedexFrmce

报道了LiKGdF_5:Er(2%),Sm(0.4%)单晶在紫外激光(三倍频Nd:YAG激光,355nm)和同步辐射真空紫外光激发下的光谱特性,讨论了不同激发下Er^(3+)离子和Sm^(3+)离子的相对发射强度及其物理机理。通过真空紫外激发光谱的测量,确定了本材料中Sm^... 详细信息

报道了LiKGdF_5:Er(2%),Sm(0.4%)单晶在紫外激光(三倍频Nd:YAG激光,355nm)和同步辐射真空紫外光激发下的光谱特性,讨论了不同激发下Er^(3+)离子和Sm^(3+)离子的相对发射强度及其物理机理。通过真空紫外激发光谱的测量,确定了本材料中Sm^(3+)离子的4f^45d吸收带以及Er^(3+)离子的4f^(10)5d吸收带的能量位置。实验结果表明,当激发Er^(3+)的4f^(10)5d吸收带,可以产生量子效率大于100%的量子剪裁现象,并给出了其物理模型。

关键词： LiKGdF5:Er(2%) Sm(0.4%)单晶真空紫外光谱量子剪裁

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