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Infrared-active phonons in one-dimensional materials and their spectroscopic signatures

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npj Computational Materials 2023年第1期9卷 331-337页

作者： norma Rivano Nicola Marzari Thibault Sohier Theory and Simulations of Materials(THEOS) École Polytechnique Fédérale de LausanneCH-1015 LausanneSwitzerland National Centre for Computational Design and Discovery of Novel Materials(MARVEL) École Polytechnique Fédérale de LausanneCH-1015 LausanneSwitzerland Laboratory for Materials Simulations Paul Scherrer Institut5232 Villigen PSISwitzerland Laboratoire Charles Coulomb(L2C) Universitéde MontpellierCNRSMontpellierFrance

Dimensionality provides a clear fingerprint on the dispersion of infrared-active,polar-optical *** these phonons,the local dipoles parametrized by the Born effective charges drive the LO-TO splitting of bulk materials;this splitting actually breaks down in two-dimensional ***,we develop the theory for one-dimensional(1D)systems—nanowires,nanotubes,and atomic and polymeric *** an analytical model with the implementation of density-functional perturbation theory in 1D boundary conditions,we show that the dielectric splitting in the dispersion relations collapses as x^(2) log(x)at the zone *** dielectric properties and the radius of the 1D materials are linked by the present work to these red shifts,opening infrared and Raman characterization avenues.

关键词： dimensional splitting dielectric

Animals as sources of food-borne pathogens: A review

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Animal Nutrition 2018年第3期4卷 250-255页

作者： norma Heredia Santos García Departamento de Microbiología e Inmunología Facultad de Ciencias Biolóogicas Universidad Autóonoma de Nuevo Leóon Apdo.Postal 124-F Ciudad Universitaria San Nicolóas de los Garza

Food-producing animals are the major reservoirs for many foodborne pathogens such as Campylobacter species, non-Typhi serotypes of Salmonella enterica, Shiga toxin-producing strains of Escherichia coli, and Listeria monocytogenes. The zoonotic potential of foodborne pathogens and their ability to produce toxins causing diseases or even death are sufficient to recognize the seriousness of the situation. This manuscript reviews the evidence that links animals as vehicles of the foodborne pathogens Salmonella,Campylobacter, Shiga toxigenic E. coli, and L. monocytogenes, their impact, and their current status. We conclude that these pathogenic bacteria will continue causing outbreaks and deaths throughout the world, because no effective interventions have eliminated them from animals and food.

关键词： Animal food Foodborne pathogens Zoonosis Enteropathogens Pathogenic bacteriara

GENERALIZED INVEXITY-TYPE CONDITIONS IN CONSTRAINED OPTIMIZATION

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Journal of Systems Science & Complexity 2011年第2期24卷 394-400页

作者： Shashi K. MISHRA norma G. RUEDA Department of Mathematics Faculty of Science Banaras Hindu University Varanasi 221005 India.Norma G. RUEDA Department of Mathematics Merrimack College North Andover MA 01845 USA.

This paper defines a new class of generalized type I functions, and obtains Kuhn-Tucker necessary and sumcient conditions and duality results for constrained optimization problems in the presence of the aforesaid weak... 详细信息

关键词： Constrained optimization duality results type I functions.

Multifaceted nature of membrane microdomains in colorectal cancer

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World Journal of Gastroenterology 2011年第6期17卷 681-690页

作者： kristina A Jahn Filip Braet Australian Centre for Microscopy and Microanalysis The University of Sydney

Membrane microdomains or lipid rafts are known to be highly dynamic and to act as selective signal transduction mediators that facilitate interactions between the cell's external and internal *** rafts play an important mediating role in the biology of cancer:they have been found in almost all existing experimental cancer models,including colorectal cancer (CRC),and play key regulatory roles in cell migration,metastasis,cell survival and tumor *** paper explores the current state of knowledge in this field by highlighting some of the pioneering and recent lipid raft studies performed on different CRC cell lines and human tissue *** this literature review,it becomes clear that membrane microdomains appear to be implicated in all key intracellular signaling pathways for lipid metabolism,drug resistance,cell adhesion,cell death,cell proliferation and many other processes in *** signal transduction pathways seem to originate directly from those peculiar lipid islands,thereby orchestrating the colon cancer cells' state and *** confirmed by recent animal and preclinical studies in different CRC models,continuing to unravel the structure and function of lipid rafts-including their associated complex signaling pathways-will likely bring us one step closer to better monitoring and treating of colon cancer patients.

关键词： Actin Caveolae Cytoskeleton Combined imaging Detergent-resistant membranes Drug targeting Electron microscopy Lipid domains Membrane rafts Prognosis Staging Tomography Lipid-mediated therapy

Hepatocellular carcinoma recurrence after liver transplantation: Risk factors, screening and clinical presentation

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World Journal of Hepatology 2019年第3期11卷 261-272页

作者： norma Arteiro Filgueira Department of Internal Medicine Universidade Federal de Pernambuco

Liver transplantation is the best treatment option for cirrhotic patients with earlystage hepatocellular carcinoma, but it faces the problem of scarcity of donors and the risk of tumor recurrence, which affects between 15% and 20% of the cases,despite the use of restrictive criteria. The risk of recurrence depends on a number of factors, related to the tumor, the patient, and the treatment, which are discussed in this review. Some of these factors are already well established, such as the histopathological characteristics of the tumor, Alpha-fetoprotein(AFP)levels, and waiting time. Other factors related to the biological behavior of the tumor and treatment should be recognized because they can be used in the refinement of the selection criteria of transplant candidates and in an attempt to reduce recurrence. This review also discusses the clinical presentation of recurrence and its prognosis, contributing to the identification of a subgroup of patients who may have better survival, if they are timely identified and *** of recurrence after the first year, with AFP levels ≤ 100 ng/mL, and single site capable of locoregional therapy are associated with better survival after recurrence.

关键词： Hepatocellular carcinoma Liver transplantation Recurrence Risk factors Alpha-fetoprotein Survival Prognosis

Time-resolved impact electrochemistry for quantitative measurement of single-nanoparticle reaction kinetics

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Nano Research 2017年第11期10卷 3680-3689页

作者： En Ning Saw Markus Kratz kristina Tschulik Micro-&Nano-Electrochemistry and Centre for Electrochemical Sciences(CES) Ruhr-University BochumBochum D-44780Germany

Single-nanoparticle electrochemistry has been established as a tool to characterize various nanomaterials based on the charge passed during their random impact at an *** it is demonstrated that the duration and shape of the resulting current peak can be used to quantify the reaction kinetics on a single-particle *** the chemical rate constant and reaction mechanism for oxidation of single nanoparticles in different electrolytes can be determined directly from the duration of the current signal recorded in high-speed,high-sensitivity current *** 29-nm-sized Ag particles in four different electrolytes as a proof of concept for this general approach,hitherto inaccessible insights into single-particle reactivity are *** comparable rate constants were measured for the four electrolytes at low overpotentials,transport-limited impacts at high overpotentials were found to depend strongly on the type and quantity of anions present in solution.

关键词： single-particle reactivity electrochemical kinetics nano-impact method silver reaction mechanism

Predisposing factors for atrial fibrillation in the elderly

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Journal of Geriatric Cardiology 2017年第3期14卷 179-184页

作者： kristina Wasmer Lars Eckardt Gunter Breithardt Division of Electrophysiology Department of Cardiovascular Medicine University Hospital Miinster Germany

Atrial fibrillation （AF） in the elderly occurs as a consequence of cardiovascular aging and an age related increase of comorbidity. Several predisposing factors for AF have been identified for the overall AF population. Most of them, cardiovascular disease in particular, play a role in younger and older patients. The longer time period during which these risk factors can cause structural changes that ultimately lead to AF may, at least in part, explain the association between age and AF. In addition, less well defined age-related changes in cellular electrophysi- ologic properties and structure predispose to AF in the elderly.

关键词： Atrial fibrillation Atrial fibrosis Mechanisms Risk factors Stroke The elderly

Rehabilitation following spinal cord injury:how animal models can help our understanding of exercise-induced neuroplasticity

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Neural Regeneration Research 2019年第3期14卷 405-412页

作者： kristina Loy Florence M.Bareyre Institute of Clinical Neuroimmunology Ludwig-Maximilians Universitat Munchen Munich Cluster of Systems Neurology (SyNergy)

Spinal cord injury is a devastating condition that is followed by long and often unsuccessful recovery after trauma. The state of the art approach to manage paralysis and concomitant impairments is rehabilitation, which is the only strategy that has proven to be effective and beneficial for the patients over the last decades. How rehabilitation influences the remodeling of spinal axonal connections in patients is important to understand, in order to better target these changes and define the optimal timing and onset of training. While clinically the answers to these questions remain difficult to obtain, rodent models of rehabilitation like bicycling, treadmill training, swimming, enriched environments or wheel running that mimic clinical rehabilitation can be helpful to reveal the axonal changes underlying motor recovery. This review will focus on the different animal models of spinal cord injury rehabilitation and the underlying changes in neuronal networks that are improved by exercise and rehabilitation.

关键词： remodeling exercise wheel running treadmill detour circuit propriospinal neuron corticospinal tract raphespinal tract reticulospinal tract activity recovery central nervous system

Human thrombin for the treatment of gastric and ectopic varices

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World Journal of Gastroenterology 2012年第41期18卷 5912-5917页

作者： norma C McAvoy John N Plevris Peter C Hayes Department of Hepatology University of EdinburghRoyal Infirmary of EdinburghEdinburgh EH16 4SAUnited Kingdom

AIM:To evaluate the efficacy of human thrombin in the treatment of bleeding gastric and ectopic ***:Retrospective observational study in a Tertiary Referral *** January 1999-October 2005,we identified 37 patients who were endoscopically treated with human thrombin injection therapy for bleeding gastric and ectopic *** details including age,gender and aetiology of liver disease/segmental portal hypertension were *** thrombin was obtained from the Scottish National Blood Transfusion Service and prepared to give a solution of 250 IU/mL which was injected via a standard injection *** patient case notes were reviewed and the total dose of thrombin given along with the number of endoscopy sessions was *** haemostasis rates,rebleeding rates and mortality were catalogued along with the incidence of any immediate complications which could be attributable to the thrombin *** duration of follow up was also *** study was conducted according to the United Kingdom research ethics ***:Thirty-seven patients were included.33 patients(89%) had thrombin(250 U/mL) for gastric varices,2(5.4%) for duodenal varices,1 for rectal varices and 1 for gastric and rectal varices.(1) Gastric varices,an average of 15.2 mL of thrombin was used per ***-bleeding occurred in 4 patients(10.8%),managed in 2 by a transjugular intrahepatic portosystemic shunt(TIPSS)(one unsuccessfully who died) and in other 2 by a distal splenorenal shunt;(2) Duodenal varices(or type 2 isolated gastric varices),an average of 12.5 mL was used per patient over 2-3 endoscopy ***-bleeding occurred in one patient,which was treated by TIPSS;and(3) Rectal varices,an average of 18.3 mL was used per patient over 3 endoscopy *** re-bleeding occurred in this ***:Human thrombin is a safe,easy to use and effective therapeutic option to control haemorrhage from gastric and ectopic varices.

关键词： Variceal haemorrhage Ectopic Varices Gastric varices, Portal hypertension Thrombin