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Marinoan glaciation in the Indian subcontinent——Anatomy and global implications

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Journal of Palaeogeography 2024年第2期13卷 293-308页

作者： h.n.Bhattacharya Department of Earth Sciences Techno India UniversityWest BengalSector VSalt LakeKolkata700091India

Detailed sedimentological analysis of the Pokaran Boulder Bed,representing the most basal unit of the neoproterozoic-Lower Cambrian Marwar Supergroup,clearly indicates its glacial *** glacial sediments are interpreted as an ice-contact submarine fan *** on the detrital and inherited zircon population of the Marwar Supergroup sediments and interlayered pyroclastic deposits,a Marinoan cryochron of the Cryogenian Period is envisaged for the Pokaran Boulder *** well-preserved Ediacaran elements in the post-glacial sedimentary succession also support a Cryogenian to Early Cambrian age of the Marwar *** glacial deposition at the base of the Marwar Supergroup strengthens the regional correlation between the studied sediments with the Lesser himalayan Blaini-Krol-Tal sediments and the haqf Supergroup of *** available zircon ages and paleomagnetic data of the Malani Igneous suite,along with the Marinoan glacial deposits,detrital zircon ages,and Ediacaran fossil elements of the Marwar Supergroup add significant information to the neoproterozoic Earth history.

关键词： neoproterozoic Marinoan glaciation Diamictites Pokaran Boulder Bed Marwar Supergroup

Langmuir-Schaefer film Investigation and Density functional Theory Band Gap Calculations of Calix[n]arene-Para-Aminobenzoic Acid for Drug nanosensor Application

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Journal of Wuhan University of Technology(Materials Science) 2024年第5期39卷 1311-1318页

作者： WOnG Yeong Yi f L Supian A Radzwan M Musa n f n Abd Karim Department of Physics Sultan Idris Education UniversityTanjong Malim 35900Malaysia Department of Chemistry Sultan Idris Education UniversityTanjong Malim 35900Malaysia

Calix[n]arenes was utilized to detect PABA,the primary sunscreen *** study investigates the interaction of calix[4]arene(C4),calix[6]arene(C6),and PABA using the Langmuir method and first-principle density functional theory(DfT).Using the Langmuir-Schaefer(LS)technique,an ultrathin film composed of calix[n]arenes and their complexes with PABA was deposited on various *** on the Langmuir study,the PABA molecule was bonded to the lower rims of both C4 and C6 with the host-guest ratio of 1:*** of the LS films formed were then characterized by ultravioletvisible spectroscopy(UV-Vis),fourier-transform infrared spectroscopy(fTIR)and carbon,hydrogen,nitrogen,sulfur elemental analyzer(ChnS).The band gap reduction obtained in the DfT study denotes the charge transfer interaction with promising reactivity between the calix[n]arenes and *** sensing of PABA by C4 and C6 is successful based on the formation of bonding between them due to the hosts’effective trapping *** outcomes of this study could be applied to drug delivery systems for future pharmaceutical and medical applications.

关键词： calix[n]arenes band gap density functional theory Langmuir-Schaefer PABA sensor

Are we ready to use new endoscopic scores for ulcerative colitis?

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World Journal of Gastroenterology 2024年第10期30卷 1466-1469页

作者： Rodrigo Quera Paulina núñez f Universidad de los Andes Inflammatory Bowel Disease ProgramClinica Universidad de los AndesDigestive Disease CenterSantiago 7600976RMChile Digestive Disease Center Inflammatory Bowel Disease ProgramClínica Universidad de los AndesSantiago 7620157Chile Department of Gastroenterology Universidad de Chile-Hospital San Juan de DiosSantiago 770123Chile

for ulcerative colitis(UC),the variability in inflammatory activity along the colon poses a challenge in *** focus on achieving endoscopic healing in UC is evident,where the UC Endoscopic Index of Severity and Mayo Endoscopic Subscore are commonly used for ***,these indices primarily consider the most severely affected *** et al recent study validates the Toronto Inflammatory Bowel Disease Global Endoscopic Reporting(TIGER)score offering a comprehensive assessment of inflammatory activity across diverse segments of the colon and rectum and a reliable index correlating strongly with UC Endoscopic Index of Severity and moderately with Mayo Endoscopic Subscore(MES).Despite recommendation,certain aspects warrant further *** calprotectin,an intermediate target,correlates with TIGER and should be *** TIGER scores defining endoscopic remission and response,evaluating agreement with histological activity,and assessing inter-endoscopist agreement for TIGER require *** the correlation between TIGER and intestinal ultrasound,akin to MES,adds value.

关键词： Ulcerative colitis Sigmoidoscopy Colonoscopy Score index

Effect of cold-working on corrosion induced damage in lug joints

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Defence Technology（防务技术） 2024年第6期36卷 175-182页

作者： Ramanath M.n Chikmath L. Murthy h. Department of Aerospace Engineering Indian Institute of Technology-MadrasChennai 600036India Department of Aeronautical Engineering KLS Gogte Institute of TechnologyBelagavi 590008India

Lug joints are preferred joineries for transferring heavy loads to parent components in aerospace *** experience corrosion due to environmental conditions,improper surface finishes and rubbing displacement between the pin and *** causes damage of different sizes and shapes near the *** degradation due to corrosion-induced damage is modelled as a through-pit at one of the identified critical locations through stress *** effect of this pit on fatigue crack initiation life is ***-hole is pre-stressed by cold-working and the benefits of inducing plastic wake on the intended performance of the lug joint during the damages due to corrosion are brought out and compared with non-cold-worked *** analysis is performed on this lug joint with *** results obtained highlight the benefits of cold-working and the methodology can be extended to damage growth and analyse the effect of surface treatments for better structural integrity of components of aerospace vehicles.

关键词： Lug joint Corrosion Crack initiation Cold-working Structural integrity

Omics-based biomarkers as useful tools in metabolic dysfunctionassociated steatotic liver disease clinical practice:how far are we?

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World Journal of Gastroenterology 2024年第14期30卷 1982-1989页

作者： Julieta Trinks María f Mascardi Adrián Gadano Sebastián Marciano Instituto de Medicina Traslacional e Ingeniería Biomédica-Consejo nacional de Investigaciones Científicas y Técnicas-Instituto Universitario del hospital Italiano-hospital Italiano de Buenos Aires Ciudad Autónoma de Buenos Aires C1199ACLArgentina Consejo nacional de Investigaciones Científicas y Técnicas Ciudad Autónoma de Buenos Aires C1425FQBArgentina Liver Unit Hospital Italiano de Buenos AiresCiudad Autónoma de Buenos Aires C1199DFArgentina Department of Research Hospital Italiano de Buenos AiresCiudad Autónoma de Buenos Aires C1199DFArgentina

Unmet needs exist in metabolic dysfunction-associated steatotic liver disease(MASLD)risk *** ability to identify patients with MASLD with advanced fibrosis and at higher risk for adverse outcomes is still *** novel biomarkers could represent a meaningful improvement to current risk *** this aim,omics technologies have revolutionized the process of MASLD biomarker discovery over the past *** the research in this field is thriving,much of the publication has been haphazard,often using single-omics data and specimen sets of convenience,with many identified candidate biomarkers but lacking clinical validation and *** we incorporate these biomarkers to direct patients’management,it should be considered that the roadmap for translating a newly discovered omics-based signature to an actual,analytically valid test useful in MASLD clinical practice is rigorous and,therefore,not easily *** article presents an overview of this area’s current state,the conceivable opportunities and challenges of omics-based laboratory diagnostics,and a roadmap for improving MASLD biomarker research.

关键词： Metabolic dysfunction-associated steatotic liver disease non-alcoholic steatohepatitis Biomarker Risk stratification Omics

formation of diffuse and spark discharges between two needle electrodes with the scattering of particles

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Plasma Science and Technology 2024年第9期26卷 32-39页

作者： Victor f TARASEnKO Dmitry V BELOPLOTOV Alexei n PAnChEnKO Dmitry A SOROKIn Institute of high Current Electronics Siberian BranchRussian Academy of SciencesTomsk 634055Russia national Research Tomsk State University Tomsk 634050Russia

The development of a nanosecond discharge in a pin-to-pin gap filled with air at atmospheric pressure has been studied with high temporal and spatial resolutions from a breakdown start to the spark *** and negative nanosecond voltage pulses with an amplitude of tens of kilovolts were ***-resolved images of the discharge development were taken with a fourchannel Intensified Charge Coupled Device(ICCD)*** minimum delay between the camera channels could be as short as≈0.1 *** made it possible to study the gap breakdown process with subnanosecond *** was observed that a wide-diameter streamer develops from the high-voltage pointed *** ionization processes near the grounded pin electrode started when the streamer crossed half of the *** bridging the gap by the streamer,a diffuse discharge was *** development of spark leaders from bright spots on the surface of the pointed electrodes was observed at the next *** was found that the rate of development of the spark leader is an order of magnitude lower than that of the wide-diameter *** thin luminous tracks were observed against the background of a discharge plasma *** has been established that the tracks are adjacent to brightly glowing spots on the electrodes and are associated with the flight of small particles.

关键词： needle electrodes short voltage pulses atmospheric air streamer breakdown diffuse and spark discharges scattering metal particles

Effects of synthesis parameters on the performance of crosslinked Co-polymers with clays for conformance control

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Petroleum Research 2024年第1期9卷 98-108页

作者： A.A.Roslan n.A.A.Aziz n.f.A.Deraman I.Dzulkarnain Petroleum Engineering Department Centre of Research Enhanced Oil Recovery(COREOR)Universiti Teknologi PETRONASSeri IskandarPerakMalaysia Chemical Engineering Department Centre of Research Enhanced Oil Recovery(COREOR)Universiti Teknologi PETRONASSeri IskandarPerakMalaysia

Conformance control or water shut-off is a technique used to improve oil *** conformance control,polymers block high permeability water areas and redistribute water drive toward unswept oil *** this study,co-polymers(denoted ATP-PGV/AM-co-AMPS)were synthesized using acrylamide(AM)and 2-acrylamide-2-methylpropane sulfonic acid(AMPS)as the monomers,polyethylene glycol(PEG)-200 and methylenebisacrylamide(MBA)as the crosslinkers,attapulgite(ATP)and bentonite(PGV)as the clay types,and ammonium persulfate(APS)as the initiator,in addition to paraffin oil and *** were synthesized using inverse emulsion polymerization with different concentrations of monomers,crosslinkers,and clays,and they were characterized using fourier-transform infrared(fTIR)spectroscopy and scanning electron microscopy(SEM)with energy dispersive X-ray spectroscopy(EDX).fTIR spectra of the samples confirmed the existence of sulfonate and hydroxyl groups,which are important for polymer ***-EDX images indicated that the morphology and elemental composition were different before and after swelling,confirming the occurrence of ***,samples were placed in sodium chloride solution(20,000 ppm)for 7 days to evaluate swelling at both room temperature and 90°*** analysis(TGA)and differential scanning calorimetry(DSC)were used to determine the thermal characteristics of the ***,rheological measurements were used to assess the deformation and rheological behavior of the *** results showed that after 1 day,good swelling without loss of mechanical strength was achieved with the composite synthesized using 10%AM,15%AMPS,6%PGV,and 10%ATP.

关键词： Polymer Clay Water shut-off Conformance Swelling

Advancements in Lynch Syndrome Management: Applying Immunotherapy for Therapeutic Success

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Open Journal of Gastroenterology 2024年第4期14卷 139-144页

作者： Abraamyan feruza Bobolis kristie Gauchan Dron Sutter Roseville Medical Center Roseville CA USA

Lynch syndrome is the fourth most common cancer in the United States, with an early age of onset and poor prognosis. here, we present a unique case of a patient with progressive colon cancer due to a late diagnosis of Lynch syndrome showing excellent response to immunotherapy. A 59-year-old male with a history of rectal cancer 30 years ago came to the hospital due to a fever and further found a large necrotic colon mass. Biopsy was positive for colorectal cancer;however, due to the size of the tumor, the patient was deemed not a surgical candidate and offered hospice with palliative chemotherapy. Based on further workup, the patient was diagnosed with Lynch syndrome, with colon cancer determined to be responsive to Immunotherapy. he was started on JEMPERLI (Dosterlimab-gxly), and after three cycles of therapy, imaging and PET scan were repeated, showing decreased activity and extent of the tumor—a tremendous success.

关键词： Lynch Syndrome Colon Cancer Genetics Immunotherapy Dostarlimab

Mitigating Urban heat Island Effects: A Review of Innovative Pavement Technologies and Integrated Solutions

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Structural Durability & health Monitoring 2024年第5期18卷 525-551页

作者： S.f.Ismael A.h.Alias n.A.haron B.B.Zaidan Abdulrahman M.Abdulghani Department of Civil Engineering Faculty of EngineeringUniversiti Putra MalaysiaSerdang43400Malaysia Central Region Heavy Civil DivisionGranite ConstructionWoodlandsTexas77381USA SP Jain School of Global Management LidcombeSydneyNSW2141Australia Department of Communication Technology and network Faculty of Computer Science and Information TechnologyUniversiti Putra MalaysiaSerdang43400Malaysia

In this review paper,we present a thorough investigation into the role of pavement technologies in advancing urban *** analysis traverses the historical evolution of these technologies,meticulously evaluating their socio-economic and environmental impacts,with a particular emphasis on their role in mitigating the urban heat island *** evaluation of pavement types and variables inﬂuencing pavement performance to be used in the multi-criteria decision-making(MCDM)framework to choose the optimal pavement application are at the heart of our *** serves to assess a spectrum of pavement options,revealing insights into the most effective and sustainable *** highlighting both the existing challenges and potential innovative solutions within theﬁeld,this paper aims to offer a directional compass for future urban planning and infrastructural *** review not only synthesizes the current state of knowledge but also aims to chart a course for future exploration,emphasizing the critical need for innovative and environmentally sensitive pavement tech-nologies in the creation of resilient and sustainable urban environments.

关键词： Pavement sustainability urban heat island environmental impact of pavements innovative pavement solutions economic and social implications sustainable development in urban areas