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Nano-Micro Letters 2022年第2期14卷 136-150页

作者： Yadong Xu Zhiqiang Lin krishnamoorthy rajavel Tao Zhao Pengli Zhu Yougen Hu Rong Sun Ching-Ping Wong Shenzhen Institute of Advanced Electronic Materials Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055People’s Republic of China School of Materials Science and Engineering Georgia Institute of TechnologyAtlantaGA 30332USA

Liquid metal(LM)has become an emerging material paradigm in the electromagnetic interference shielding field owing to its excellent electrical conductivity.However,the processing of lightweight bulk LM composites with finite package without leakage is still a great challenge,due to high surface tension and pump-out issues of LM.Here,a novel confined thermal expansion strategy based on expandable microsphere(EM)is proposed to develop a new class of LM-based monoliths with 3D continuous conductive network.The EM/LM monolith(EM/LMm)presents outstanding performance of lightweight like metallic aerogel(0.104 g cm^(-1)),high strength(3.43 MPa),super elasticity(90%strain),as well as excellent tailor ability and recyclability,rely on its unique gas-filled closed-cellular structure and refined LM network.Moreover,the assembled highly conducting EM/LMm exhibits a recorded shielding effectiveness(98.7 dB)over a broad frequency range of 8.2-40 GHz among reported LM-based composites at an ultra-low content of LM,and demonstrates excellent electromagnetic sealing capacity in practical electronics.The ternary EM/LM/Ni monoliths fabricated by the same approach could be promising universal design principles for multifunctional LM composites,and applicable in magnetic responsive actuator.

关键词： Liquid metal Elastic monolith Confined thermal expansion Electromagnetic interference shielding Magnetic actuation

Identification of gene classifier and modules associated with SARS-CoV-2 ARI in nasal swab

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Genes & Diseases 2024年第1期11卷 38-41页

作者： Pandikannan krishnamoorthy Athira S.Raj Himanshu Kumar Department of Biological Sciences Laboratory of Immunology and Infectious Disease BiologyIndian Institute of Science Education and Research(llSER)BhopalBhopalMP 462066India Laboratory of Host Defense WPl ImmunologyFrontier ResearchCentreOsakaUniversityOsaka 5650871Japan

During a sudden viral pandemic,where the pathogenesis and nature of the infection are unclear,early and accurate identification of the patients infected with the pandemiccausing pathogen is crucial to prevent excess mortality.During the coronavirus disease 2019(COvID-19)pandemic,early diagnosis of severe acute respiratory syndrome virus-2(SARS-CoV-2)is limited by the incidence of the symptoms that are shared with acute respiratory illnesses(ARl)caused by other pathogens.

关键词： acute diagnosis respiratory

Role of fecal microbiota transplant in management of hepatic encephalopathy: Current trends and future directions

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World Journal of Hepatology 2024年第1期16卷 17-32页

作者： Yash R Shah Hassam Ali Angad Tiwari David Guevara-Lazo Natalia Nombera-Aznaran Bhanu Siva Mohan Pinnam Manesh Kumar Gangwani Harishankar Gopakumar Amir H Sohail SriLakshmiDevi Kanumilli Ernesto Calderon-Martinez Geetha krishnamoorthy Nimish Thakral Dushyant Singh Dahiya Department of Internal Medicine Trinity Health Oakland/Wayne State UniversityPontiacMI 48341United States Division of Gastroenterology and Hepatology East Carolina University/Brody School of MedicineGreenvilleNC 27858United States Department of Internal Medicine Maharani Laxmi Bai Medical CollegeJhansi 284001India Faculty of Medicine Universidad Peruana Cayetano HerediaLima 15102Peru Department of Internal Medicine John H.Stroger Hospital of Cook CountyChicagoIL 60612United States Department of Internal Medicine The University of ToledoToledoOH 43606United States Department of Gastroenterology and Hepatology University of Illinois College of Medicine at PeoriaPeoriaIL 61605United States Department of Surgery University of New MexicoAlbuquerqueNM 87106United States Department of Internal Medicine GSL Medical CollegeRajamahendravaram 533296India Department of Internal Medicine Universidad Nacional Autonoma de MexicoCiudad De Mexico 04510Mexico Department of Digestive Diseases and Nutrition University of KentuckyLexingtonKY 40536United States Division of Gastroenterology Hepatology&MotilityThe University of Kansas School of MedicineKansas CityKS 66160United States

Fecal microbiota transplantation(FMT)offers a potential treatment avenue for hepatic encephalopathy(HE)by leveraging beneficial bacterial displacement to restore a balanced gut microbiome.The prevalence of HE varies with liver disease severity and comorbidities.HE pathogenesis involves ammonia toxicity,gut-brain communication disruption,and inflammation.FMT aims to restore gut microbiota balance,addressing these factors.FMT's efficacy has been explored in various conditions,including HE.Studies suggest that FMT can modulate gut microbiota,reduce ammonia levels,and alleviate inflammation.FMT has shown promise in alcohol-associated,hepatitis B and C-associated,and non-alcoholic fatty liver disease.Benefits include improved liver function,cognitive function,and the slowing of disease progression.However,larger,controlled studies are needed to validate its effectiveness in these contexts.Studies have shown cognitive improvements through FMT,with potential benefits in cirrhotic patients.Notably,trials have demonstrated reduced serious adverse events and cognitive enhancements in FMT arms compared to the standard of care.Although evidence is promising,challenges remain:Limited patient numbers,varied dosages,administration routes,and donor profiles.Further large-scale,controlled trials are essential to establish standardized guidelines and ensure FMT's clinical applications and efficacy.While FMT holds potential for HE management,ongoing research is needed to address these challenges,optimize protocols,and expand its availability as a therapeutic option for diverse hepatic conditions.

关键词： Hepatic encephalopathy Fecal microbiota transplant Cognitive impairment Liver cirrhosis Chronic liver disease

The theory of pathological simile:unveiling the essence of homoeopathy

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History & Philosophy of Medicine 2024年第1期6卷 1-2页

作者： Sibin Ramabhadran Anandavally Sruthi Krishna Gopukumar Sivakumar Thangam Nivedha krishnamoorthy Sajitha Kumari Department of Organon of Medicine Sarada Krishna Homoeopathic Medical College(Affiliated to The Tamil Nadu Dr.M.G.R.Medical UniversityChennai)Tamilnadu 629161India Department of Repertory Sarada Krishna Homoeopathic Medical College(Affiliated to The Tamil Nadu Dr.M.G.R.Medical UniversityChennai)Tamilnadu 629161India Research Facilitation Centre Sarada Krishna Homoeopathic Medical College(Affiliated to The Tamil Nadu Dr.M.G.R.Medical UniversityChennai)Tamilnadu 629161India

Background Homoeopathy,a therapeutic method based on the principle of‘Similia Similibus Curentur’(like cures like),has been widely practiced and studied since its discovery by Dr.Samuel Hahnemann in the late 18th century.Over time,numerous homoeopathic stalwarts have contributed to the development and understanding of this system of medicine.Dr.Richard Hughes,a remarkable figure in the field of homoeopathy,has left an indelible mark on the development and understanding of this extraordinary system of medicine.

关键词： simile has since

Modeling ash deposition and shedding during oxy-combustion of coal/rice husk blends at 70%inlet O_(2)

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International Journal of Coal Science & Technology 2023年第2期10卷 196-209页

作者： Gautham krishnamoorthy Department of Chemical Engineering UPSON Ⅱ Room 365241 Centennial DriveUniversity of North DakotaGrand ForksND 58202-7101USA

Co-firing rice husk(RH)and coal with carbon capture using oxy-combustion presents a net carbon negative energy produc-tion opportunity.In addition,the high fusion temperature of the non-sticky,silica rich,RH can mitigate ash deposition as well as promote shedding of deposits.To identify the optimum operating conditions,fuel particle sizes,and blend ratios that minimize ash deposition,a Computational Fluid Dynamic methodology with add-on ash deposition and shedding models were employed to predict outer ash deposition and shedding rates during co-combustion of coal/RH in AIR and O2/CO_(2)(70/30 vol%,OXY70)oxidizer compositions.After ensuring that the fly-ash particle size distributions and particle Stokes numbers near the deposition surface were accurately represented(to model impaction),appropriate models for coal ash and RH ash viscosities that were accurate in the temperature region(1200-1300 K)of interest in this study were identified.A particle viscosity and kinetic energy(PKE)based capture criterion was enforced to model the ash capture.An erosion/shed-ding criterion that takes the deposit melt fraction and the energy consumed during particle impact into account was also implemented.Deposition rate predictions as well as the deposition rate enhancement(OXY70/AIR)were in good agreement with measured values.While the OXY70 scenario was associated with a significant reduction(60%-70%)in flue gas velocities,it also resulted in larger fly-ash particles.As a result,the PKE distributions of the erosive RH ash were similar in both scenarios and resulted in similar shedding rates.

关键词： CFD Oxy-Combustion Ash Deposition Shedding Co-firing

SMS Encryption and Decryption Using Modified Vigenere Cipher Algorithm

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Journal of the Operations Research Society of China 2022年第4期10卷 835-848页

作者： B.Bazeer Ahamed Murugan krishnamoorthy Department of Information Technology Al Musanna College of TechnologyMuladdah314Sultanate of Oman School of Computer Science and Engieering Vellore Institute of TechnologyVelloreTamil Nadu632014India

Despite many online messaging services,short message service(SMS)is still used because of its simplicity.However,such services can be easily cracked,making SMS more vulnerable to send confidential information.Therefore,appropriate cryptographic algorithms must be applied to ensure security.One of the most common cryptographic techniques used for encrypting and decrypting messages is the Vigenere cipher.However,Vigenere cipher can be cracked easily because the previous approach involved 26×10 matrixes,and the key comprised of alphabets.If the key length is small,then it becomes easier to crack the plain text by permutation.So here in this work,we have proposed a modified Vigenere cipher technique to enhance its security standards.Existing Vigenere cipher attack is not more secured,and thus we developed a method that improves the security in Vigenere cipher using Rivest-Shamir-Adleman(RSA).RSA is an asymmetric algorithm that has public and private keys.The advantage of using this algorithm is that finding factors for the large composite numbers is difficult.This method is secured but time consuming.In this proposed method,we combined RSA with Vigenere cipher so that the proposed algorithm is secured and consumes less time than RSA algorithm.This approach is widely used to encrypt SMS.

关键词： Cipher Rivest-Shamir-Adleman(RSA) Short message service(SMS) Security

Improvised Seagull Optimization Algorithm for Scheduling Tasks in Heterogeneous Cloud Environment

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Computers, Materials & Continua 2023年第2期74卷 2461-2478页

作者： Pradeep Krishnadoss Vijayakumar Kedalu Poornachary Parkavi krishnamoorthy Leninisha Shanmugam Vellore Institute of Technology Chennai632014India

Well organized datacentres with interconnected servers constitute the cloud computing infrastructure.User requests are submitted through an interface to these servers that provide service to them in an on-demand basis.The scientific applications that get executed at cloud by making use of the heterogeneous resources being allocated to them in a dynamic manner are grouped under NP hard problem category.Task scheduling in cloud poses numerous challenges impacting the cloud performance.If not handled properly,user satisfaction becomes questionable.More recently researchers had come up with meta-heuristic type of solutions for enriching the task scheduling activity in the cloud environment.The prime aim of task scheduling is to utilize the resources available in an optimal manner and reduce the time span of task execution.An improvised seagull optimization algorithm which combines the features of the Cuckoo search(CS)and seagull optimization algorithm(SOA)had been proposed in this work to enhance the performance of the scheduling activity inside the cloud computing environment.The proposed algorithm aims to minimize the cost and time parameters that are spent during task scheduling in the heterogeneous cloud environment.Performance evaluation of the proposed algorithm had been performed using the Cloudsim 3.0 toolkit by comparing it with Multi objective-Ant Colony Optimization(MO-ACO),ACO and Min-Min algorithms.The proposed SOA-CS technique had produced an improvement of 1.06%,4.2%,and 2.4%for makespan and had reduced the overall cost to the extent of 1.74%,3.93%and 2.77%when compared with PSO,ACO,IDEA algorithms respectively when 300 vms are considered.The comparative simulation results obtained had shown that the proposed improvised seagull optimization algorithm fares better than other contemporaries.

关键词： Cloud computing task scheduling cuckoo search(CS) seagull optimization algorithm(SOA)

Improved Specificity for Breast Cancer Screening Using an Oncogenic(miRNA-21)and a Gene Suppressor(miRNA-195)miRNA in the Serum for a Point of Care(POC)Screening Solution

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Biomedical and Environmental Sciences 2023年第6期36卷 549-552页

作者： krishnamoorthy Kokilavani Ancy Terryna Chanayiltharayil John Bindu Salim Madhulika Vijayakumar Sankar Ganesh Jeyaraj PSG Institute of Advanced Studies Avinashi RoadPeelameduCoimbatore641004 PSG Institute of Medical Science and Research Avinashi Road PeelameduCoimbatore641004 PSG Center for Molecular Medicine and Therapeutics PSG Institute of Medical Sciences and ResearchCoimbatoreTamil Nadu641004India PSG Centre for Genetics and Molecular Biology Off Avinashi RoadPeelameduCoimbatoreTamil Nadu641004India

The overall incidence and burden caused by breast cancer is increasing,affecting the global socio-economic development and life expectancy[1].According to“WHO Global Breast Cancer Initiative(GBCI)reports”,if the mortality rate due to breast cancer can be reduced by 2.4%annually,we may prevent 2.5 million breast cancer deaths between2020-2040.

关键词： Breast Cancer Serum

Implications of turbulent shear on clay floc break-up along the Atlantic estuary(Bouregreg),Morocco

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International Journal of Sediment Research 2022年第2期37卷 248-257页

作者： krishnamoorthy Lakshmi Ammal Priya Soufiane Haddout Joan Cecilia Catubig Casila Department of Civil Engineering TKM College of Engineering Department of Physics Faculty of Science Ibn Tofail University Land and Water Resources Division IABE CEAT University of the Philippines Los Ba?os

Water depth,salinity,current,and suspended sediment concentration(SSC) were measured along with the grain size distribution of bed sediment along an estuarine longitudinal section.The floc size increased with increase in the percentage of clay and silt,while decreased with increase in the percentage of sand content of bed sediment.The turbulent shear,G,had a direct effect on floc size with its value increasing with increase in G up to a G value of 15 s,while an inverse relation existed between floc size and G at higher G(C> 15 s).Further,higher turbulence enabled sand to get resuspended and cause additional shear leading to the break-up of flocs.An attempt was made to modify G to account for the combined effect of water turbulence(C) and shear imparted by sand(C) and the impact of the modification of G on the predictability of floc size was evaluated.A new model was developed which explains floc size in terms of sediment concentration(C),salinity gradient(S),and G for different scenarios based on the value of G.Sensitivity analysis was done for observed floc size(FS) and predicted floc size using four approaches:(Ⅰ) FS β C~χ;(Ⅱ) FS α C~χS;(Ⅲ) FS α C~χSG~z for G 15 s; and(Ⅳ) FS α C~χSGfor G> 15 sand G=G+G,where x,y,and z are determined by calibration.It was observed that the predictability of the floc size improved when the turbulence was modified to account for shear imparted by sand so that the coefficient of determination was increased from 0.78 for model Ⅲ to 0.89 for model Ⅳ.Further,the settling velocity was expressed as a function of suspended sediment concentration,turbulent shear,and salinity gradient.The predictability of settling velocity was improved(R~2 increased from 0.77 to 0.86) when the additional turbulence created by sand was incorporated in the non-dimensional empirical equation.The study highlights the influence of sand in causing the break-up of flocs and suggests that for turbulence shear values high enough to resuspend sand,and G has to be modified to account for th

关键词： Floc size Settling velocity Turbulent shear Non-cohesive sediment Bouregreg estuary Morocco

Recent trends,challenges,and perspectives in piezoelectric-driven self-chargeable electrochemical supercapacitors

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Carbon Energy 2022年第5期4卷 833-855页

作者： Karthikeyan krishnamoorthy Parthiban Pazhamalai Sindhuja Manoharan Noor Ul Haq Liyakath Ali Sang-Jae Kim Nanomaterials&System Lab Major of Mechatronics EngineeringFaculty of Applied Energy SystemJeju National UniversityJejuSouth Korea Research Institute of Energy New Industry Jeju National UniversityJejuSouth Korea Nanomaterials&System Lab Major of Mechanical System EngineeringCollege of EngineeringJeju National UniversityJejuSouth Korea

The increasing demand for wearable electronic devices has resulted in tremendous progress in research on energy harvesting and storage devices/technologies.Energy storage devices require a power source to charge them,whereas energy harvesting devices require a storage compartment to store the harvested energy for sustainable delivery.Recently,a piezoelectrically driven self-charging supercapacitor power cell(SCSPC)was developed to harvest and store electrical energy in a solitary system to determine the potential impact of these two types of energy devices for wearable electronic applications.This review describes the recent advances in piezoelectric-driven SCSPCs in terms of device configuration,piezoelectric separator,electrolyte types,electrode materials,current collectors,and system integration.This review focuses specifically on the principles and mechanism of the self-charging process that occurred in the SCSPCs and the use of a promising piezo electrochemical spectroscopic tool to realize the piezo electrochemical energy transfer and storage process in the SCSPCs.Further,the current challenges and new perspectives for future developments in the emerging area of SCSPCs or integrated energy devices are discussed.

关键词： electrospinning integrated energy cell mechanical energy piezoelectric separators piezoelectrochemical spectroscopy self-charging supercapacitor power cell