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Biomedical and Environmental Sciences 2023年第6期36卷 549-552页

作者： krishnamoorthy kokilavani Ancy Terryna Chanayiltharayil John Bindu Salim Madhulika Vijayakumar Sankar Ganesh Jeyaraj PSG Institute of Advanced Studies Avinashi RoadPeelameduCoimbatore641004 PSG Institute of Medical Science and Research Avinashi Road PeelameduCoimbatore641004 PSG Center for Molecular Medicine and Therapeutics PSG Institute of Medical Sciences and ResearchCoimbatoreTamil Nadu641004India PSG Centre for Genetics and Molecular Biology Off Avinashi RoadPeelameduCoimbatoreTamil Nadu641004India

The overall incidence and burden caused by breast cancer is increasing,affecting the global socio-economic development and life expectancy[1].According to“WHO Global Breast Cancer Initiative(GBCI)reports”,if the mortality rate due to breast cancer can be reduced by 2.4%annually,we may prevent 2.5 million breast cancer deaths between2020-2040.

关键词： Breast Cancer Serum

Modeling ash deposition and shedding during oxy-combustion of coal/rice husk blends at 70%inlet O_(2)

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International Journal of Coal Science & Technology 2023年第2期10卷 196-209页

作者： Gautham krishnamoorthy Department of Chemical Engineering UPSON Ⅱ Room 365241 Centennial DriveUniversity of North DakotaGrand ForksND 58202-7101USA

Co-firing rice husk(RH)and coal with carbon capture using oxy-combustion presents a net carbon negative energy produc-tion *** addition,the high fusion temperature of the non-sticky,silica rich,RH can mitigate ash deposition as well as promote shedding of *** identify the optimum operating conditions,fuel particle sizes,and blend ratios that minimize ash deposition,a Computational Fluid Dynamic methodology with add-on ash deposition and shedding models were employed to predict outer ash deposition and shedding rates during co-combustion of coal/RH in AIR and O2/CO_(2)(70/30 vol%,OXY70)oxidizer *** ensuring that the fly-ash particle size distributions and particle Stokes numbers near the deposition surface were accurately represented(to model impaction),appropriate models for coal ash and RH ash viscosities that were accurate in the temperature region(1200-1300 K)of interest in this study were identified.A particle viscosity and kinetic energy(PKE)based capture criterion was enforced to model the ash *** erosion/shed-ding criterion that takes the deposit melt fraction and the energy consumed during particle impact into account was also *** rate predictions as well as the deposition rate enhancement(OXY70/AIR)were in good agreement with measured *** the OXY70 scenario was associated with a significant reduction(60%-70%)in flue gas velocities,it also resulted in larger fly-ash *** a result,the PKE distributions of the erosive RH ash were similar in both scenarios and resulted in similar shedding rates.

关键词： CFD Oxy-Combustion Ash Deposition Shedding Co-firing

Guided cell migration on a graded micropillar substrate

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Bio-Design and Manufacturing 2020年第1期3卷 60-70页

作者： Srikumar krishnamoorthy Zhengyi Zhang Changxue Xu Department of Industrial Manufacturingand Systems EngineeringTexas Tech UniversityLubbockTX 79409USA School of Naval Architecture and Ocean Engineering Huazhong University of Science and TechnologyWuhan 430074China

Cell migration is facilitated by the interaction of living cells and their local *** local topography is one of the key factors regulating cell *** between the surface topography and the cell behaviors is critical to understanding tissue development and *** this study,a dynamic mask photolithography technique has been utilized to fabricate a surface with graded *** has been demonstrated that the cells have been successfully guided to migrate from the sparse zone to the dense *** cell polarization angle has been characterized in both sparse zone and the dense *** to the dense zone,the cells in the sparse zone are more aligned along the direction of the micropillar spacing gradient,which enables the guided cell ***,the effects of the micropillar spacing gradient,micropillar diameter,and micropillar height have been investigated in terms of the cell migration speed and cell spreading ***,two issues significantly affecting the cell migration have been discussed:trapped cells between the micropillars and cell clusters.

关键词： Guided cell migration Graded microtopography Cell polarization

Sedimentation model and analysis for differential settling of two-particle-size suspensions in the Stokes region

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International Journal of Sediment Research 2010年第2期25卷 119-133页

作者： P. krishnamoorthy Department of Chemistry.Arignar Anna Government Arts College

A model is developed for predicting the settling velocity in suspensions of particles of two different sizes based on experimental data for the settling rate of two-size suspensions in various liquids using particles of equal density. In these experiments, the retarding effect of the smaller particles on the settling velocities of the larger ones is taken into account. The model considers Steinour’s fundamental equation and assumes a fixed arrangement of particles and constant velocity in a single-size suspension under creeping flow conditions and the flow spaces changing in shape and size with the volumetric concentration of solids. Based on the foregoing, a simplified model equation is proposed for the settling of particles in a suspension as a function of their free fall velocity and of the solids concentration. Different experimental conditions are used to show the effect of solids concentration, liquid density, and viscosity on the settling behaviour of the glass beads with low particle Reynolds numbers and bed porosity ranging from 0.62 to 0.95. The present study involves the lower and upper interface velocities of two-size suspensions of solids in liquids (concentrated and dilute suspensions) covering a wide range in the properties of the liquids and solids, and more specifically in solids concentration (Glass beads and Sand).

关键词： Settling velocity Suspended sediment Fluid properties Solid concentration

Study on the Effect of Surface Modification on the Mechanical and Thermal Behaviour of Flax,Sisal and Glass Fiber

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Journal of Renewable Materials 2019年第2期7卷 153-169页

作者： C.M.Meenakshi A.krishnamoorthy Department of Mechanical Engineering Sathyabama Institute of Science and TechnologyChennaiTamil NaduIndia

Natural fiber-reinforced hybrid composites can be a better replacement for plastic composites since these plastic composites pose a serious threat to the *** aim of this study is to analyze the effect of surface modification of the natural fibers on the mechanical,thermal,hygrothermal,and water absorption behaviors of flax,sisal,and glass fiber-reinforced epoxy hybrid *** mechanical properties of alkaline treated sisal and flax fibers were found to increase ***,flexural and impact strength of glass/flax-fiber-reinforced hybrid samples improved by 58%,36%,and 51%,respectively,after surface alkaline *** addition,the hygrothermal analysis and water absorption capacity are studied and also the Interfacial bonding properties were analyzed using Scanning Electron Microscopic *** thermal analysis using thermogravimetric analyzer reveals that the decomposition temperature for hybrid fiber reinforced composites are between 306 and 312℃.In conclusion,surface treatment improves the performance of natural fiber in hybrid fiber-reinforced composites,particularly flax fiber.

关键词： Hybrid composite surface treatments mechanical testing thermal analysis hygrothermal testing water absorption SEM analysiss

SMS Encryption and Decryption Using Modified Vigenere Cipher Algorithm

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Journal of the Operations Research Society of China 2022年第4期10卷 835-848页

作者： B.Bazeer Ahamed Murugan krishnamoorthy Department of Information Technology Al Musanna College of TechnologyMuladdah314Sultanate of Oman School of Computer Science and Engieering Vellore Institute of TechnologyVelloreTamil Nadu632014India

Despite many online messaging services,short message service(SMS)is still used because of its ***,such services can be easily cracked,making SMS more vulnerable to send confidential ***,appropriate cryptographic algorithms must be applied to ensure *** of the most common cryptographic techniques used for encrypting and decrypting messages is the Vigenere ***,Vigenere cipher can be cracked easily because the previous approach involved 26×10 matrixes,and the key comprised of *** the key length is small,then it becomes easier to crack the plain text by *** here in this work,we have proposed a modified Vigenere cipher technique to enhance its security *** Vigenere cipher attack is not more secured,and thus we developed a method that improves the security in Vigenere cipher using Rivest-Shamir-Adleman(RSA).RSA is an asymmetric algorithm that has public and private *** advantage of using this algorithm is that finding factors for the large composite numbers is *** method is secured but time *** this proposed method,we combined RSA with Vigenere cipher so that the proposed algorithm is secured and consumes less time than RSA *** approach is widely used to encrypt SMS.

关键词： Cipher Rivest-Shamir-Adleman(RSA) Short message service(SMS) Security

Histidine‑Stabilized Copper Nanoclusters as a Fluorescent Probe for Selective and Sensitive Determination of Vitamin B_(12)

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Journal of Analysis and Testing 2018年第2期2卷 168-174页

作者： krishnamoorthy Shanmugaraj Thangarasu Sasikumar Malaichamy Ilanchelian Centre for Nanoscience and Nanotechnology Department of ChemistryThe Gandhigram Rural InstituteGandhigramDindigulTamil Nadu 624302India Department of Chemistry Bharathiar UniversityCoimbatoreTamil Nadu 641046India

Herein,we report the highly sensitive and selective determination of vitamin B_(12)(VB_(12))using histidine-stabilized copper nanoclusters(His-CuNCs)as a fluorescent probe by the spectrofluorometry *** as-synthesized His-CuNCs were characterized by UV–Vis absorption,steady-state emission,and high-resolution transmission electron microscopy ***-CuNCs exhibited an emission maximum around 443 nm,when excited at 350 *** emission intensity of His-CuNCs was significantly quenched by the addition of VB_(12),hinting that the synthesized probe can be employed for sensing of VB_(12).Based on the decrease in emission intensity,the concentration of VB_(12) was determined and the emission intensity of His-CuNCs can be quenched by VB_(12) via fluorescence resonance energy-transfer ***-CuNCs showed high selectivity toward the determination of VB_(12) in the presence of other potentially interfering vitamins,cations,and *** addition,the proposed sensing platform displayed a sensitive response to VB_(12) in the linear range of 4.00–28.00×10^(−6) mol dm^(−3) with a limit of detection of 3.30×10^(−9) mol dm^(−3).The proposed sensing system is simple,low cost,selective,and sensitive for the determination of VB_(12) in biological samples.

关键词： Histidine-stabilized copper nanoclusters Energy transfer Spectrofluorometry Emission quenching Vitamin B_(12)

Identification of gene classifier and modules associated with SARS-CoV-2 ARI in nasal swab

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Genes & Diseases 2024年第1期11卷 38-41页

作者： Pandikannan krishnamoorthy Athira S.Raj Himanshu Kumar Department of Biological Sciences Laboratory of Immunology and Infectious Disease BiologyIndian Institute of Science Education and Research(llSER)BhopalBhopalMP 462066India Laboratory of Host Defense WPl ImmunologyFrontier ResearchCentreOsakaUniversityOsaka 5650871Japan

During a sudden viral pandemic,where the pathogenesis and nature of the infection are unclear,early and accurate identification of the patients infected with the pandemiccausing pathogen is crucial to prevent excess *** the coronavirus disease 2019(COvID-19)pandemic,early diagnosis of severe acute respiratory syndrome virus-2(SARS-CoV-2)is limited by the incidence of the symptoms that are shared with acute respiratory illnesses(ARl)caused by other pathogens.

关键词： acute diagnosis respiratory

Improvised Seagull Optimization Algorithm for Scheduling Tasks in Heterogeneous Cloud Environment

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Computers, Materials & Continua 2023年第2期74卷 2461-2478页

作者： Pradeep Krishnadoss Vijayakumar Kedalu Poornachary Parkavi krishnamoorthy Leninisha Shanmugam Vellore Institute of Technology Chennai632014India

Well organized datacentres with interconnected servers constitute the cloud computing *** requests are submitted through an interface to these servers that provide service to them in an on-demand *** scientific applications that get executed at cloud by making use of the heterogeneous resources being allocated to them in a dynamic manner are grouped under NP hard problem *** scheduling in cloud poses numerous challenges impacting the cloud *** not handled properly,user satisfaction becomes *** recently researchers had come up with meta-heuristic type of solutions for enriching the task scheduling activity in the cloud *** prime aim of task scheduling is to utilize the resources available in an optimal manner and reduce the time span of task *** improvised seagull optimization algorithm which combines the features of the Cuckoo search(CS)and seagull optimization algorithm(SOA)had been proposed in this work to enhance the performance of the scheduling activity inside the cloud computing *** proposed algorithm aims to minimize the cost and time parameters that are spent during task scheduling in the heterogeneous cloud *** evaluation of the proposed algorithm had been performed using the Cloudsim 3.0 toolkit by comparing it with Multi objective-Ant Colony Optimization(MO-ACO),ACO and Min-Min *** proposed SOA-CS technique had produced an improvement of 1.06%,4.2%,and 2.4%for makespan and had reduced the overall cost to the extent of 1.74%,3.93%and 2.77%when compared with PSO,ACO,IDEA algorithms respectively when 300 vms are *** comparative simulation results obtained had shown that the proposed improvised seagull optimization algorithm fares better than other contemporaries.

关键词： Cloud computing task scheduling cuckoo search(CS) seagull optimization algorithm(SOA)

Autonomous reinforcement learning agent for chemical vapor deposition synthesis of quantum materials

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npj Computational Materials 2021年第1期7卷 983-991页

作者： Pankaj Rajak Aravind krishnamoorthy Ankit Mishra Rajiv Kalia Aiichiro Nakano Priya Vashishta Argonne Leadership Computing Facility Argonne National LaboratoryArgonneILUSA Collaboratory for Advanced Computing and Simulations University of Southern CaliforniaLos AngelesCAUSA Department of Chemical Engineering&Materials Science University of Southern CaliforniaLos AngelesCAUSA Department of Physics&Astronomy University of Southern CaliforniaLos AngelesCAUSA Department of Computer Science University of Southern CaliforniaLos AngelesCAUSA

Predictive materials synthesis is the primary bottleneck in realizing functional and quantum *** for synthesis of promising materials are currently identified by time-consuming trial and error and there are no known predictive schemes to design synthesis parameters for *** use offline reinforcement learning(RL)to predict optimal synthesis schedules,i.e.,a time-sequence of reaction conditions like temperatures and concentrations,for the synthesis of semiconducting monolayer MoS2 using chemical vapor *** RL agent,trained on 10,000 computational synthesis simulations,learned threshold temperatures and chemical potentials for onset of chemical reactions and predicted previously unknown synthesis schedules that produce well-sulfidized crystalline,phase-pure *** model can be extended to multi-task objectives such as predicting profiles for synthesis of complex structures including multi-phase heterostructures and can predict long-time behavior of reacting systems,far beyond the domain of molecular dynamics simulations,making these predictions directly relevant to experimental synthesis.

关键词： materials synthesis synthesis