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A matched-pair analysis of laparoscopic versus open pancreaticoduodenectomy: oncological outcomes using Leeds Pathology Protocol

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Hepatobiliary & Pancreatic Diseases International 2014年第4期13卷 435-441页

作者： Abdul R Hakeem Caroline S verbeke Alison Cairns Amer Aldouri Andrew M Smith krishna v menon Department of HPB and Transplant Surgery St James's University Hospital NHS TrustLeeds Teaching Hospitals Beckett street Leeds LS9 7TF United Kingdom Division of Pathology Department of Laboratory Medicine Karolinska Institutet Stockholm Sweden Department of Histopathology St James's University Hospital NHS TrustLeeds Teaching Hospitals Beckett street Leeds LS9 7TF United Kingdom

BACKGROUND： Laparoscopic pancreaticoduodenectomy（LPD）is a safe procedure. Oncological safety of LPD is still a matter for debate. This study aimed to compare the oncological outcomes,in terms of adequacy of resection and recurrence rate following LPD and open pancreaticoduodenectomy（OPD）.METHODS： Between November 2005 and April 2009, 12LPDs（9 ampullary and 3 distal common bile duct tumors）were performed. A cohort of 12 OPDs were matched for age,gender, body mass index（BMI） and American Society of Anesthesiologists（ASA） score and tumor ***： Mean tumor size LPD vs OPD（19.8 vs 19.2 mm,P=0.870）. R0 resection was achieved in 9 LPD vs 8 OPD（P=1.000）. The mean number of metastatic lymph nodes and total number resected for LPD vs OPD were 1.1 vs 2.1（P=0.140）and 20.7 vs 18.5（P=0.534） respectively. Clavien complications grade I/II（5 vs 8）, III/Iv（2 vs 6） and pancreatic leak（2 vs 1）were statistically not significant（LPD vs OPD）. The mean high dependency unit（HDU） stay was longer in OPD（3.7 vs 1.4 days,P〈0.001）. There were 2 recurrences each in LPD and OPD（logrank,P=0.983）. Overall mortality for LPD vs OPD was 3 vs 6（log-rank, P=0.283） and recurrence-related mortality was 2 vs *** was one death within 30 days in the OPD group secondary to severe sepsis and none in the LPD ***： Compared to open procedure, LPD achieved a similar rate of R0 resection, lymph node harvest and longterm recurrence for tumors less than 2 cm. Though technically challenging, LPD is safe and does not compromise oncological outcome.

关键词： pancreaticoduodenectomy minimally invasive laparoscopic open oncological outcomes resection margins pathology

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New variation of median arcuate ligament compression causing hepatic arterial hypoperfusion during liver transplantation

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Hepatobiliary & Pancreatic Diseases International 2020年第4期19卷 394-395页

作者： Noel Cassar Stephen Gregory krishna menon Institute of Liver Studies King’s Healthcare PartnersDenmark Hill SiteLondon SE59RSUK

Satisfactory blood flow after hepatic arterial anastomosis in liver transplantation is a critical point of the *** with this anastomosis can result in hepatic artery thrombosis with resultant graft failure and patient morbidity and *** of hepatic artery thrombosis include problematic technique,hepatic artery dissection,external compression(*** hematoma),hypercoagulable state,splenic arterial steal and rarer causes such as median arcuate ligament compression(MALC).A careful review of preoperative radiology and imaging will reveal these rare instances and enable a proper intraoperative plan.

关键词： hepatic arterial ligament

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The Rationale for Reviewing Current Concepts of Urban Planning and Developing New Ones in India

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Built Heritage 2017年第3期1卷 34-43页

作者： A.G.krishna menon Departments of Architecture and Urban Design School of Planning and ArchitectureNew DelhiIndia

Urban planning in India is heir to a colonial paradigm that imposed practices developed from the experiences of Western urbanisation to the local Indian *** paper suggests that this paradigm exacerbates the complex problems of contemporary urbanisation,but there is little attempt among Indian urban planners to acknowledge and address the consequences of their colonial *** forces of globalisation are reinforcing this postcolonial intellectual malaise by reposing greater faith in capital-and technology-intensive solutions to solve problems instead of reforming the inherited processes of urban *** paper argues that the nascent field of urban conservation in India offers the potential to review the dominant paradigms of urban planning and develop more context-specific and appropriate strategies for tackling the problems of Indian urbanisation.

关键词： historic space historic metropolitan context evolution reflection

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Comparative efficacy of hyperbaric bupivacaine vs hyperbaric ropivacaine in spinal anesthesia for cesarean section:A metaanalysis

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World Journal of Methodology 2025年第2期15卷 154-165页

作者： Rishi Anand Deb Sanjay Nag Roushan Patel Prashant Sharma vamsi krishna Uppalapati Umesh Kumar Singh Department of Anaesthesiology Tata Main HospitalJamshedpur 831001JhārkhandIndia

BACKGROUND Intrathecal bupivacaine is the traditional anesthetic drug used in spinal anesthesia for caesarean sections(CSs),but ropivacaine has emerged as a potential *** meta-analysis compares the efficacy and safety of intrathecal hyper-baric bupivacaine vs hyperbaric ropivacaine for cesarean *** To systematically evaluate and compare the efficacy and safety of intrathecal hyperbaric bupivacaine and hyperbaric ropivacaine for spinal anesthesia in *** A thorough search of electronic databases was carried out to find pertinent randomized controlled trials(RCTs)comparing intrathecal hyperbaric ropi-vacaine and hyperbaric bupivacaine during ***,Cochrane database,Google Scholar,and Scopus were searched,and papers from January 2000 to January 2024 were deemed eligible and filtered using predetermined inclusion and exclusion *** were assessed for methodological quality,and data were extracted for time to adequate anesthesia(sensory and motor blockade),duration of sensory and motor block,hemodynamic changes and side effect *** standardized mean difference with 95%CI was used for continuous *** variables were assessed using the Mantel-Haenszel test and the random effect model to compute the odds *** Total 8 RCTs were selected from a pool of 119 search results for *** meta-analysis evaluated pooled effect sizes and assessed heterogeneity among the *** primary objective was to compare key outcomes to identify any significant variances in efficacy and safety profiles between two local *** analysis revealed that the difference in the onset of sensory blockade between the two local anesthetics was statistically insignificant(P=0.1586).However,the onset of motor blockade appeared to be faster with bupivacaine(P=0.03589).Additionally,the regression of sensory and motor blockade occurred earlier in the ropivacaine ***,the duration of the first analgesic

关键词： Ropivacaine Bupivacaine Anesthesia Spinal Cesarean section Meta-analysis

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Enhanced saturation magnetization in La^(3+) doped NiCo ferrites prepared by sol-gel auto-combustion method

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Journal of Rare Earths 2024年第8期42卷 1546-1554,I0005页

作者： Maddileti Jelli vidyasagar Thopudurthy krishna Reddy C.v. Department of Physics Rayalaseema UniversityKurnoolA.P518007.Iindia Department of Physics Government PolytechnicRayachotiA.P516269India

Lanthanum doped nickel-cobalt nano ferrites with chemical formula Ni_(0.5)Co_(0.5)LaxFe_(2-x)O_(4)(x=0.05,0,10,0.15 and 0,20) were prepared using a simple sol-gel auto combustion *** basic structural properties were determined by X-ray diffraction method and the formation of single phased spinel ferrite was *** crystalline size decreased from 25 to 11 nm and lattice parameter a increases with increase of La *** surface morphology of these ferrites was observed by field-emission scanning electron microscopy(FESEM) and agglomerated irregular grains are observed with increase of the rare earth element La ***-dispersive X-ray spectroscopy(EDX) result confirms the presence of the required *** Fourier transform infrared spectroscopy(FTIR) spectrum indicates the formation of the spinel ferrite structure with M-O *** direct band measurements from ultraviolet-visible spectroscopy(Uv-vis) spectroscopy indicate that the direct band gap decreases from 1.39 to 1.19 ev for x=0.05 to x=0.15,then increases to 1.28 ev for x=*** room temperature magnetic properties of these ferrites were studied by a vibrating sample magnetometer(vSM).The enhanced saturation magnetization of 49.73 emu/g is observed for x=0.10 and then saturation magnetizations are gradually decreased for x=0.15 and x=*** the remanent magnetization and coercivity also follow the same trend.

关键词： Ferrites Sol-gel auto combustion La doping Magnetic properties Rare earths

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Selective Removal of Photocatalytically Active Anatase TiO_(2)Phase from Mixed-Phase TiO_(2)-ZnO Nanocomposites:Impact on Physicochemical Properties and Photocatalytic Activity

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Energy & Environmental Materials 2020年第4期3卷 548-559页

作者： Nambath Gayathri menon Sankara Sarma v.Tatiparti Suparna Mukherji Centre for Research in Nanotechnology and Science Indian Institute of Technology BombayMumbai Maharashtra 400076India Department of Energy Science and Engineering Indian Institute of Technology BombayMumbai Maharashtra 400076India Environmental Science and Engineering Department Indian Institute of Technology BombayMumbai Maharashtra 400076India

TiO_(2)-ZnO nanocomposites were synthesized by varying Ti:Zn molar ratio from 1:0.1(TZ-1:0.1)to 1:1(TZ-1:1).With increase in Zn content,from TZ-1:0.1 to TZ-1:0.2,anatase transformed to rutile ***-1:0.3,which contained a blend of phases,including rutile and anatase TiO_(2),ZnO,and zinc titanates,exhibited the narrowest bandgap(2.5±0.1 e v),and showed the highest photocatalytic ***-1:1 was predominated by zinc *** the nanocomposites exhibited narrower bandgaps compared to pure TiO_(2)nanoparticles,facilitating visible light *** study was designed to explore whether a method targeting the removal of a specific crystalline phase(anatase)influenced the properties and photocatalytic activity of the *** dissolution not only removed anatase phase,but also led to significant loss of crystallinity,widened the bandgap,and adversely affected photocatalytic performance,in nanocomposites that contained>80%anatase phase(TZ-1:0.1 and TZ-1:0.2).However,in nanocomposites that contained less of anatase phase(TZ-1:0.3and TZ-1:1),the morphology,bandgap,crystallinity,and the extent of photocatalytic activity at the end of 240 min remained largely *** activity in TZ-1:0.3 and TZ-1:1 originated from a blend of phases comprising of less photocatalytically active phases,such as rutile TiO_(2),Zn TiO3,and Zn2TiO4,rather than from the anatase *** Ti:Zn molar ratio controlled the phases present in TiO_(2)-ZnO nanocomposites,which,in turn,controlled the physicochemical properties and visible light ***,in nanocomposites that contained a mix of several phases,the properties and photocatalytic activity were not dependent on anatase phase.

关键词： anatase TiO_(2) TiO_(2)–ZnO nanocomposites visible light photocatalysis

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validation of Foreground Emission Model using GALEX Medium Observations

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Research in Astronomy and Astrophysics 2023年第6期23卷 228-237页

作者： Nimmi Narayanan Shivashankar S.menon N.v.Sujatha Department of Physics St.Xavier's College for WomenAluva 683101India Department of Physics Sree Sankara CollegeKaladyErnakulam 683574India CSIS BITS Pilani K.K.Birla Goa CampusZuarinagarGoa 403726India

The study of diffuse ultraviolet(Uv)background radiation is vital in the investigation of stellar and galactic ***-based Uv observations are comprised of both foreground and background *** foreground emission in an observation is a result of solar contamination in the direction of *** our previous work,we modeled airglow(one of the major constituents of the foreground emission)as a function of10.7 cm Solar Flux and Sun Angle with great accuracy using GALEX deep *** adopt a similar methodology to validate the obtained model and run equivalent experiments here using far-Uv(FUv)and nearUv(NUv)GALEX medium imaging surveys(MIS)with a total exposure time greater than 3300 *** obtained a predictive model having excellent compatibility with the earlier *** analysis shows that the total foreground emission varies between 59 and 295 photon units in FUv whereas in NUv,it varies between 671 and1195 photon units depending upon the date and time of *** also noticed a strong correlation between the background emission and optical depth both in FUv and NUv,especially in the low density *** clearly indicates that the major contributor in diffuse background radiation is the starlight scattered by interstellar dust grains.

关键词： instrumentation:detectors Sun:activity ultraviolet:ISM atmospheric effects

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Biomimetics of Campaniform Sensilla:Measuring Strain from the Deformation of Holes

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Journal of Bionic Engineering 2007年第2期4卷 63-76页

作者： Julian F. v. vincent Sally E. Clift Carlo menon Department of Mechanical Engineering The University of BathBath BA2 7AYUK Advanced Concepts Team European Space Agency2201 AZ NoordwijkThe Netherlands

We present a bio-inspired strategy for designing embedded strain sensors in space structures. In insects, the campaniform sensillum is a hole extending through the cuticle arranged such that its shape changes in response to loads. The shape change is rotated through 90° by the suspension of a bell-shaped cap whose deflection is detected by a cell beneath the cuticle. It can be sensitive to displacements of the order of 1 nm. The essential morphology, a hole formed in a plate of fibrous composite mate- rial, was modelled by Skordos et al. who showed that global deformation of the plate （which can be flat, curved or a tube） induces higher local deformation of the hole due to its locally higher compliance. Further developments reported here show that this approach can be applied to groups of holes relative to their orientation. , The morphology of the sensillum in insects suggests that greater sensitivity can be achieved by arranging several holes in a regular pattern; that if the hole is oval it can be ＂aimed＂ to sense specific strain directions; and that either by controlling the shape of the hole or its relationship with other holes it can have a tuned response to dynamic strains. We investigate space applications in which novel bio-inspired strain sensors could successfully be used.

关键词： campaniform sensillum strain displacement compliance hole remote sensing fibrous composite

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AN M/M/C RETRIAL QUEUEING SYSTEM WITH BERNOULLI vACATIONS

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Journal of Systems Science and Systems Engineering 2009年第2期18卷 222-242页

作者： B.krishna KUMAR R.RUKMANI v.THANGARAJ Department of Mathematics College of EngineeringAnna UniversityChennai600 025India Department of Mathematics Pachaiyappa's CollegeChennai600030India Ramanujan Institute for Advanced Study in Mathematics University of MadrasChennai600 005India

In this paper, a steady-state Markovian multi-server retrial queueing system with Bernoulli vacation scheduling service is studied. Using matrix-geometric approach, various interesting and important system performance measures are obtained. Further, the probability descriptors like ideal retrial and vain retrial are provided. Finally, extensive numerical illustrations are presented to indicate the quantifying nature of the approach to obtain solutions to this queueing system.

关键词： Retrial queue Bernoulli vacation matrix-geometric methods busy period vain retrial ideal retrial

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Multi-Scale Compliant Foot Designs and Fabrication for Use with a Spider-Inspired Climbing Robot

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Journal of Bionic Engineering 2008年第3期5卷 189-196页

作者： Dan Sameoto Carlo menon MENRvA Group School of Engineering Science Simon Fraser University Burnaby BC V5A 1S6 Canada

Climbing robots are of potential use for surveillance, inspection and exploration in different environments. In particular, the use of climbing robots for space exploration can allow scientists to explore environments too challenging for traditional wheeled designs. To adhere to surfaces, biomimetic dry adhesives based on gecko feet have been proposed. These biomimetic dry adhesives work by using multi-scale compliant mechanisms to make intimate contact with different surfaces and adhere by using van der Waals forces. Fabrication of these adhesives has frequently been challenging however, due to the difficulty in combining macro, micro and nanoscale compliance. We present an all polymer foot design for use with a hexapod climbing robot and a fabrication method to improve reliability and yield. A high strength, low-modulus silicone, TC-5005, is used to form the foot base and microscale fibres in one piece by using a two part mold. A macroscale foot design is produced using a 3D printer to produce a base mold, while lithographic definition of microscale fibres in a thick photoresist forms the ＇hairs＇ of the polymer foot. The adhesion of the silicone fibres by themselves or attached to the macro foot is examined to determine best strategies for placement and removal of feet to maximize adhesion. Results demonstrate the successful integration of micro and macro compliant feet for use in climbing on a variety of surfaces.

关键词： biomimetics dry adhesive gecko climbing robot MEMS silicone

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