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Fibrinogen degradation product levels on arrival for trauma patients requiring a transfusion even without head injury

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World Journal of Emergency Medicine 2017年第2期8卷 106-109页

作者： Youichi Yanagawa kouhci ishikawa Kci Jitsuiki Toshihiko Yoshizawa Yasumasa Oodc Kazuhiko Omori Hiromichi Ohsaka Department of Acute Critical Care Medicine Shizuoka HospitalJuntendo UniversityNagaoka Izunokuni City ShizuokaJapan

BACKGROUND: There have been few reports on the clinical significance of the fibrinogen degradation product(FDP) level in trauma patients with and without head injury. We retrospectively analyzed trauma patients with or without head injury to investigate the clinical signifi cance of the FDP ***: From April 2013 to June 2015, a medical chart review was retrospectively performed for all patients with trauma. The exclusion criteria included patients who did not receive a transfusion. The patients were divided into two groups: a FDP>100 group, which included patients who had an FDP level on arrival over 100 ng/m L, and a FDP≤100 ***: The ratio of open fractures and the prothrombin ratio in the FDP>100 group were significantly smaller than those observed in the FDP≤100 group. The average age, ratio of blunt injury, Injury Severity Score(ISS), volume of transfusion and mortality ratio in the FDP>100 group were signifi cantly greater than those in the FDP≤100 group. There was a weakly positive correlation between the FDP level and ISS(R=0.35, P=0.002), but it was not associated with the transfusion volume. The results of an analysis excluding patients with head injury showed a similar ***: The FDP levels may be a useful biochemical parameter for the initial evaluation of the severity of trauma and mortality even in blunt traumatized patients without head injury or with stable vital signs.

关键词： Fibrinogen degradation product Injury Severity Score Transfusion Mortality

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