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Quantum Meteorites: An Extemporaneous Description of the System of the World

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Journal of Modern Physics 2015年第7期6卷 878-889页

作者： jean-paul Auffray Courant Institute of Mathematical Sciences New York University New York NY USA

We extemporaneously summarize the theoretical scheme we have introduced recently in this note to account for the (hidden) functioning of the System of the World at the quantum level. We further explore the relevance, the pertinence and the potential validity of this scheme. We obtain new fundamental results, bearing notably on the nature and the origin of the “virtual particles” conventionally called upon in quantum field theories to explain the Casimir Effect. We define the concept of quantum meteorites in this context. We disable the Heisenberg Uncertainty Principle, judged to be a (mis) interpretation of otherwise legitimate observations, and we replace it with our new XQP Absolute Certainty Principle.

关键词： Xonic Quantum Physics Casimir Effect Virtual Photons Uncertainty Principle Planck Length Quantum Meteorites

<i>E</i>Infinity, the Zero Set, Absolute Space and the Photon Spin

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Journal of Modern Physics 2015年第5期6卷 536-545页

作者： jean-paul Auffray ex: Courant Institute of Mathematical Sciences New York University New York USA ex: American Institute of Physics New York USA

As defined and used in General Relativity calculations, spacetime is a strictly classical construct which does not incorporate in any way, shape or form the concept of quantum. While reviewing the efforts that Alexandria theoretician M. S. El Naschie has made to resolve the dichotomy, we discovered that his E infinity theory contains a Cantor set which has characteristics specified by Isaac Newton for Absolute space. We show that this unexpected connection leads to an understanding of the mysterious origin of the one and only attribute that all particles listed in the Standard Model of Elementary Particles possess—including notably the photon—and which has remained unexplained hitherto: spin. This most rewarding result reinforces our belief in the relevance of the E infinity basic concepts in relation to our own Xonic Quantum Physics (XQP) which places dynamical action rather spacetime and energy at the core of the System of the World.

关键词： Quantum Foam E Infinity Xonic Quantum Physics Newton Absolute Space Photon Spin

Comparative research on integrated development of large river basins:a case study of the Yangtze and the Rhone

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Journal of Geographical Sciences 2006年第3期16卷 378-382页

作者： LIU Hui jean-paul Bravard CAI Zongxia Thierry Sanjuan Institute of Geographic Sciences and Natural Resources Research CAS Beijing 100101 China Lyon 2 University U.M.R. 5600 France Paris 1 University U.M.R. 8561 Paris F-75005 France

Since 2001, the French and Chinese researchers have done a cooperative research on the comparison of integrated development of large fiver basins. The Yangtze River was chosen as a crux of this research and linked with other older river experiments like the Rhone, the Nile and the Mississippi. This research includes not only the environmental issues but also economic and social issues. One special issue journal has been published in French for our research results. Other two collective and comparative books in French and Chinese will be finished at the end of this year. In the future, the comparison should be widened to Italy （the Po）, Egypt （the Nile development planning） and the United States （the Mississippi Basin） and we would like to enlarge our research group and want to link up different teams and research projects, in order to get a global understanding of large fiver regions phenomenon.

关键词： large river basin integrated development Yangtze River Rhone

Telehealth in the management of diabetes mellitus in China

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Chinese Medical Journal 2012年第23期125卷 4307-4311页

作者： ZHU Bin LIU Mai-lan XU Shu-qiang Jun Chen Collet jean-paul Collet Scott A Lear LI Ping Institute of Clinical Medical Sciences China-Japan Friendship Hospital Beijing 100029 China Child and Family Research Institute Vancouver Canada Acupuncture and Tuina College Chengdu University of Traditional Chinese Medicine Chengdu Sichuan 610072 China Infection Prevention and Control Service Provincial Health Service Authority British Columbia Canada UBC Department of Pediatrics Child and Family Research Institute Vancouver Canada Faculty of Health Sciences Simon Fraser University Harbour Centre Campus Vancouver Canada

Telehealth was defined as the use of information, computers and telecommunication technologies to provide health related services when health professionals and patients are separated by a distance This new medical model involves video-conference, transmission of images, e-health portals, remote monitoring of vital signs, and continuing medical education as a whole to help patients to improve health care. It should consist of three parts, including the patient client, the specialist and the connector （platform and intemet）.

关键词： telehealth diabetes mellitus management of diabetes

Disaster Risk Management Through the Design Safe Cyberinfrastructure

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International Journal of Disaster Risk Science 2020年第6期11卷 719-734页

作者： jean-paul Pinelli Maria Esteva Ellen M.Rathje David Roueche Scott J.Brandenberg Gilberto Mosqueda Jamie Padgett Frederick Haan Department of Mechanical and Civil Engineering Florida Institute of TechnologyMelbourneFL 32901USA Texas Advanced Computing Center University of Texas at AustinAustinTX 78712USA Department of Civil Engineering University of Texas at AustinAustinTX 78712USA Department of Civil Engineering Auburn UniversityAuburnAL 36849USA Department of Civil and Environmental Engineering University of California in Los AngelesLos AngelesCA 90095USA Department of Structural Engineering University of California in San DiegoLa JollaCA 92093USA Department of Civil and Environmental Engineering Rice UniversityHoustonTX 77005USA Engineering Department Calvin CollegeGrand RapidsMI 49546USA

Design Safe addresses the challenges of supporting integrative data-driven research in natural hazards *** is an end-to-end data management,communications,and analysis platform where users collect,generate,analyze,curate,and publish large data sets from a variety of sources,including experiments,simulations,field research,and post-disaster *** achieves key objectives through:(1)integration with high performance and cloud-computing resources to support the computational needs of the regional risk assessment community;(2)the possibility to curate and publish diverse data structures emphasizing relationships and understandability;and(3)facilitation of real time communications during natural hazards events and disasters for data and information *** resultant services and tools shorten data cycles for resiliency evaluation,risk modeling validation,and forensic *** article illustrates salient features of the *** summarizes its design principles,architecture,and *** focus is on case studies to show the impact of Design Safe on the disaster risk *** Next Generation Liquefaction project collects and standardizes case histories of earthquake-induced soil liquefaction into a relational database—Design Safe—to permit users to interact with the *** can correlate in Design Safe building dynamic characteristics based on data from building sensors,with observed damage based on ground motion *** groups upload,curate,and publish wind,seismic,and coastal damage data they gather during field reconnaissance missions,so these datasets are available shortly after a *** a part of the education and community outreach efforts of Design Safe,training materials and collaboration space are also offered to the disaster risk management community.

关键词： Cyberinfrastructure Design Safe Disaster risk management Natural hazard data management

Differences in characteristics of patients with and without known risk factors for hepatocellular carcinoma in the United States

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World Journal of Gastroenterology 2007年第5期13卷 781-784页

作者： Jon D Dorfman Richard Schulick Michael A Choti jean-Francois H Geschwind Ihab Kamel Michael Torbenson paul J Thuluvath Department of Surgery The Johns Hopkins University School of Medicine Baltimore MD 21205 United States Department of Radiology The Johns Hopkins University School of Medicine Baltimore MD 21205 United States Department of Pathology The Johns Hopkins University School of Medicine Baltimore MD 21205 United States Department of Medicine The Johns Hopkins University School of Medicine Baltimore MD 21205 United States

AIM： To examine the clinical characteristics of a subgroup of patients with hepatocellular carcinoma （HCC） and compare them to those with known risk factors. METHODS： We used the HCC database of 306 patients seen at our institution from January 1, 1995 to December 31, 2001. Of the 306 patients, 63 （20%, group 1） had no known risk factors （hepatitis C virus, hepatitis B virus, alcohol, hemochromatosis or cirrhosis from any cause） and 243 （group 2） had one or more risk factors. RESULTS： The median age was similar in both groups, but there were disproportionate numbers of younger （〈 30 years old）, older （〉 80 years） patients, women （33% vs 18%）, and Caucasians （81% vs 52%） in group 1 as compared to group 2. There were fewer Asians （2% vs 11%） and African Americans （13% vs 27%） in group 1. Abdominal pain （70% vs 37%） was more common while gastrointestinal bleeding （0% vs 11%） and ascites （4% vs17%） were less common in group i compared to group 2. Group 1 had larger tumor burden （median size 9.4 cm vs 5.7 cm） at the time of presentation, but there were no differences in the site （right, left or bilateral lesions）, or number of tumors between the two groups. CONCLUSION： HCC patients without identifiable risk factors have different characteristics and clinical presentation compared to those with known risk *** of cirrhosis and larger tumor burden may explain the differences in the presenting symptoms.

关键词： Hepatocellular carcinoma Patient charaocteristics Risk factors

Petrogenesis, LA-ICP-MS zircon U-Pb geochronology and geodynamic implications of the Kribi metavolcanic rocks,Nyong Group, Congo craton

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Acta Geochimica 2022年第3期41卷 470-495页

作者： Hermine Mvodo Sylvestre Ganno Gus Djibril Kouankap Nono Donald Hermann Fossi Philomene Estelle Nga Essomba Marvine Nzepang Tankwa jean paul Nzenti Department of Earth Sciences University of YaoundéIP.O.Box 812YaoundeCameroon Department of Geology HTTCUniversity of BamendaP.O.Box 39BambiliBamendaCameroon Institute for Geological and Mining Research P.O.Box 4110YaoundéCameroon Faculty of Mines and Petroleum Industries University of MarouaKaélé08MarouaCameroon

Metavolcanic rocks are well-exposed in the Kribi area within the Nyong Group, Congo craton, but their origin, age, and tectonic significance are poorly *** we report integrated field mapping and petrography,geochemistry, and LA-ICP-MS zircon U-Pb ages of these metavolcanic rocks to constrain their petrogenesis and geodynamic implications. The studied rocks consist of mafic granulite, garnet-amphibole gneiss, and garnet-biotite gneiss, and occur interbanded with sharp contact and intruded by syenite dyke. These metavolcanic rocks are classified as MORB-like tholeiitic to calc-alkaline basalts,basaltic andesite, and rhyodacite rocks with within-plate setting geochemical signatures. The metabasite rocks(basalt to basaltic andesite protolith) are likely the equivalent of a spinel peridotite product representing ~ 2–5 %partial melting of metasomatized mantle source, while the metarhyodacite rocks are derived from the fractional crystallization of the same parental magma. Zircon U-Pb data revealed that the rhyodacite rocks initially formed at2671 ± 51 Ma and underwent later metamorphism at2065 ± 55 Ma. The Neoarchean protolith age is comparable to the ca. 2628 Ma tholeiitic magmatism and ca.2666 Ma high-K granites, suggesting bimodal Neoarchean magmatic event within the Ntem Complex, while the metamorphic ages fall within the ca. 2100–2000 Ma highgrade tectono-metamorphic event attributed to Eburnean/Trans-Amazonian orogeny. At the regional scale,metavolcanic rocks with similar origins and ages are documented in the Sa o Francisco Craton in Brazil, suggesting comparable geodynamic evolution on both sides of the south Atlantic during the Paleoproterozoic.

关键词： Metavolcanic rocks MORB Within plate volcanic zone Mantle source Fractional crystallization Congo craton Cameroon

Compound screening platform using human induced pluripotent stem cells to identify small molecules that promote chondrogenesis

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Protein & Cell 2012年第12期3卷 934-942页

作者： Sheng-Lian Yang Erica Harnish Thomas Leeuw Uwe Dietz Erika Batchelder paul SWright Jane Peppard paul August Cecile Volle-Challier Francoise Bono jean-Marc Herbert Juan Carlos Izpisua Belmonte Gene Expression Laboratories The Salk Institute for Biological Studies10010 N.Torrey Pines Rd.La JollaCA 92037USA Sanofi US R&DEarly to Candidate UnitTucson Research Center2090 E.Innovation Park DriveTucsonAZ 85755USA Sanofi Deutschland GmbH R&DTSU Aging Quality of LifeIndustriepark HoechstFrankfurt am Main 65926Germany Sanofi R&D Early to Candidate Unit195Route d'Espagne-BP 13669ToulouseFrance Center of Regeneration Medicine Dr.Aiguader 88Barcelona 08003Spain

Articular cartilage,which is mainly composed of collagen Ⅱ,enables smooth skeletal *** of collagen Ⅱ can be caused by various events,such as injury,but degeneration especially increases over the course of normal ***,the body does not fully repair itself from this type of degeneration,resulting in impaired ***,an articular cartilage repair surgical technique,has been commonly used in the clinic to induce the repair of tissue at damage *** stem cells(MSC)have also been used as cell therapy to repair degenerated ***,the therapeutic outcomes of all these techniques vary in different patients depending on their age,health,lesion size and the extent of damage to the *** repairing tissues either form fibrocartilage or go into a hypertrophic stage,both of which do not reproduce the equivalent functionality of endogenous hyaline *** of the reasons for this is inefficient chondrogenesis by endogenous and exogenous *** that promote chondrogenesis could be used to induce self-repair of damaged cartilage as a non-invasive approach alone,or combined with other techniques to greatly assist the therapeutic *** recent development of human induced pluripotent stem cell(iPSCs),which are able to self-renew and differentiate into multiple cell types,provides a potentially valuable cell resource for drug screening in a“more relevant”cell *** we report a screening platform using human iPSCs in a multi-well plate format to identify compounds that could promote chondrogenesis.

关键词： hESC hiPSC chondrogenesis compound screening platform

Expert group syndrome at high altitude

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Sports Medicine and Health Science 2022年第3期4卷 215-218页

作者： jean-paul Richalet Marie-Anne Magnan Alice Gavet Pierre Lafère UniversitéSorbonne Paris Nord Laboratoire Hypoxie et PoumonUMR INSERM U1272BobignyFrance Institut National des Sports de l’Expertise et de la PerformancePôle médicalParisFrance Hôpitaux universitaires de Genève Département de médecine aiguëUnitéde médecine subaquatique et hyperbareGenevaSwitzerland Hôpitaux du Mont-Blanc Soins de suite et réadaptationChamonixFrance Universitéde Bretagne Occidentale Laboratoire ORPHYEA 44324BrestFrance HauteÉcole Bruxelles-Brabant(HE2B) EnvironmentalOccupationalAgeing(Integrative)Physiology LaboratoryBrusselsBelgium

During a training session for the university diploma of Mountain medicine delivered by University Sorbonne Paris Nord for medical doctors,one of the participants developed signs of maladaptation to high altitude at 3600 m,the severity of which was incorrectly *** was sparingly given by the patient(an anesthetist)to several of his colleagues and no one was in charge to collect clinical data,take a history,and provide appropriate *** combination of the absence of designation of a supervising doctor and the difficulty of communicating with the patient led to a lack of coordinated management and to an evolution of the symptoms towards severe acute mountain ***,the very rapid management of the patient and a rapid helicopter evacuation,as soon as the symptoms worsened towards the onset of a suspected high altitude cerebral and/or pulmonary edema,allowed rapid resolution without ***,medical,psychological,and managerial factors led to this Expert Group Syndrome.

关键词： Acute mountain sickness High altitude cerebral edema Psychology Group management